Tyrosine phosphatases in steroidogenic cells: Regulation and function

Molecular and Cellular Endocrinology

Volumn 265-266, Issue SUPPL., 2007, Pages 131-137

  Gorostizaga, Alejandra ^a   Cornejo Maciel, Fabiana ^a   Brion, Laura ^a   Maloberti, Paula ^a   Podestá, Ernesto J ^a   Paz, Cristina ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Acyl CoA synthetase; Hydroxylase; MAP kinase phosphatase; StAR; Tyrosine phosphatases

Indexed keywords

CORTICOTROPIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; HORMONE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROTEIN TYROSINE PHOSPHATASE; SERINE; THREONINE;

ADRENAL CORTEX CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; GENE INDUCTION; HORMONE ACTION; HUMAN; LEYDIG CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; STEROIDOGENESIS; TRANSCRIPTION REGULATION;

ADRENAL CORTEX; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION; HUMANS; LEYDIG CELLS; MALE; PROTEIN-TYROSINE-PHOSPHATASE; STEROIDS; TRANSCRIPTION, GENETIC;

EID: 33847044361     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.12.009     Document Type: Review

References (54)

1. Bey P., Gorostizaga A.B., Maloberti P.M., Lozano R.C., Poderoso C., Cornejo Maciel F., Podesta E.J., and Paz C. Adrenocorticotropin induces mitogen-activated protein kinase phosphatase 1 in Y1 mouse adrenocortical tumor cells. Endocrinology 144 (2003) 1399-1406
2. Bourdeau A., Dube N., and Tremblay M.L. Cytoplasmic protein tyrosine phosphatases, regulation and function: the roles of PTP1B and TC-PTP. Curr. Opin. Cell Biol. 17 (2005) 203-209
3. Burridge K., Turner C.E., and Romer L.H. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J. Cell Biol. 119 (1992) 893-903
4. Cano F., Poderoso C., Cornejo Maciel F., Castilla R., Maloberti P., Castillo F., Neuman I., Paz C., and Podesta E.J. Protein tyrosine phosphatases regulate arachidonic acid release, StAR induction and steroidogenesis acting on a hormone-dependent arachidonic acid-preferring acyl-CoA synthetase. J. Steroid Biochem. Mol. Biol. 99 (2006) 197-202
5. Clark B.J., Wells J., King S.R., and Stocco D.M. The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). J. Biol. Chem. 269 (1994) 28314-28322
6. 2+-dependent signal pathways in Rat-1 cells. J. Biol. Chem. 272 (1997) 13309-13319
7. Cornejo Maciel F., Poderoso C., Gorostizaga A., Paz C., and Podesta E.J. LH/chorionic gonadotropin signaling pathway involves protein tyrosine phosphatase activity downstream of protein kinase A activation: evidence of an obligatory step in steroid production by Leydig cells. J. Endocrinol. 170 (2001) 403-411
8. Cornejo Maciel F., Maloberti P., Neuman I., Cano F., Castilla R., Castillo F., Paz C., and Podesta E.J. An arachidonic acid-preferring acyl-CoA synthetase is a hormone-dependent and obligatory protein in the signal transduction pathway of steroidogenic hormones. J. Mol. Endocrinol. 34 (2005) 655-666
9. Crivello J.F., and Jefcoate C.R. Intracellular movement of cholesterol in rat adrenal cells. Kinetics and effects of inhibitors. J. Biol. Chem. 255 (1980) 8144-8151
10. Dowd S., Sneddon A.A., and Keyse S.M. Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterization of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases. J. Cell Sci. 111 (1998) 3389-3399
11. Dufau M.L., Tsuruhara T., Horner K.A., Podesta E., and Catt K.J. Intermediate role of adenosine 3′:5′-cyclic monophosphate and protein kinase during gonadotropin-induced steroidogenesis in testicular interstitial cells. Proc. Natl. Acad. Sci. U.S.A. 74 (1977) 3419-3423
12. Finkielstein C., Maloberti P., Mendez C.F., Paz C., Cornejo Maciel F., Cymeryng C., Neuman I., Dada L., Mele P.G., Solano A., and Podesta E.J. An adrenocorticotropin-regulated phosphoprotein intermediary in steroid synthesis is similar to an acyl-CoA thioesterase enzyme. Eur. J. Biochem. 256 (1998) 60-66
13. Gorostizaga A., Brion L., Maloberti P., Poderoso C., Podesta E.J., Cornejo Maciel F., and Paz C. Molecular events triggered by heat shock in Y1 adrenocortical cells. Endocr. Res. 30 (2004) 655-659
14. Gorostizaga A., Brion L., Maloberti P., Cornejo Maciel F., Podesta E.J., and Paz C. Heat shock triggers MAPK activation and MKP-1 induction in Leydig testicular cells. Biochem. Biophys. Res. Commun. 327 (2005) 23-28
15. Groom L.A., Sneddon A.A., Alessi D.R., Dowd S., and Keyse S.M. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J. 15 (1996) 3621-3632
16. Gyles S.L., Burns C.J., Whitehouse B.J., Sugden D., Marsh P.J., Persaud S.J., and Jones P.M. ERKs regulate cyclic AMP-induced steroid synthesis through transcription of the steroidogenic acute regulatory (StAR) gene. J. Biol. Chem. 276 (2001) 34888-34895
17. Hall P.F., and Almahbobi G. Roles of microfilaments and intermediate filaments in adrenal steroidogenesis. Microsc. Res. Tech. 36 (1997) 463-479
18. Han J.D., and Rubin C.S. Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells. J. Biol. Chem. 271 (1996) 29211-29215
19. Hirakawa T., and Ascoli M. The lutropin/choriogonadotropin receptor-induced phosphorylation of the extracellular signal-regulated kinases in Leydig cells is mediated by a protein kinase a-dependent activation of ras. Mol. Endocrinol. 17 (2003) 2189-2200
20. Hu M.C., Hsu N.C., Pai C.I., Wang C.K., and Chung B. Functions of the upstream and proximal steroidogenic factor 1 (SF-1)-binding sites in the CYP11A1 promoter in basal transcription and hormonal response. Mol. Endocrinol. 15 (2001) 812-818
21. Kelly K., and Chu Y. The regulation of MAP kinase pathways by MAP kinase phosphatases. In: Gutkin J.S. (Ed). Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Another Diseases (2000), Humana Press, New Jersey 165-182
22. Keyse S.M. Protein phosphatases and the regulation of mitogen-activated protein kinase signaling. Curr. Opin. Cell Biol. 12 (2000) 186-192
23. Koritz S.B., and Kumar A.M. On the mechanism of action of the adrenocorticotrophic hormone. The stimulation of the activity of enzymes involved in pregnenolone synthesis. J. Biol. Chem. 245 (1970) 152-159
24. Le T., and Schimmer B.P. The regulation of MAPKs in Y1 mouse adrenocortical tumor cells. Endocrinology 142 (2001) 4282-4287
25. Lee S.L., Sadovsky Y., Swirnoff A.H., Polish J.A., Goda P., Gavrilina G., and Milbrandt J. Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science 273 (1996) 1219-1221
26. Liu Z., and Stocco D.M. Heat shock-induced inhibition of acute steroidogenesis in MA-10 cells is associated with inhibition of the synthesis of the steroidogenic acute regulatory protein. Endocrinology 138 (1997) 2722-2728
27. Maloberti P., Lozano R.C., Mele P.G., Cano F., Colonna C., Mendez C.F., Paz C., and Podesta E.J. Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells. Eur. J. Biochem. 269 (2002) 5599-5607
28. Maloberti P., Castilla R., Castillo F., Cornejo Maciel F., Mendez C.F., Paz C., and Podesta E.J. Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis. FEBS J. 272 (2005) 1804-1814
29. Murphy B.D., Lalli E., Walsh L.P., Liu Z., Soh J., Stocco D.M., and Sassone-Corsi P. Heat shock interferes with steroidogenesis by reducing transcription of the steroidogenic acute regulatory protein gene. Mol. Endocrinol. 15 (2001) 1255-1263
30. Naville D., Penhoat A., Durand P., and Begeot M. Three steroidogenic factor-1 binding elements are required for constitutive and cAMP-regulated expression of the human adrenocorticotropin receptor gene. Biochem. Biophys. Res. Commun. 255 (1999) 28-33
31. Paz C., Dada L., Cornejo Maciel F., Mele P., Cymeryng C., Neuman I., Mendez C., Finkielstein C., Solano A., Minkiyu P., Fisher W.H., Towbin H., Scartazzini R., and Podesta E.J. Purification of a novel 43-kDa protein (p43) intermediary in the activation of steroidogenesis from rat adrenal gland. Eur. J. Biochem. 224 (1994) 709-716
32. Paz C., Cornejo Maciel F., Mendez C., and Podesta E.J. Corticotropin increases protein tyrosine phosphatase activity by a cAMP-dependent mechanism in rat adrenal gland. Eur. J. Biochem. 265 (1999) 911-918
33. Paz C., Cornejo Maciel F., Poderoso C., Gorostizaga A., and Podesta E.J. An ACTH-activated protein tyrosine phosphatase (PTP) is modulated by PKA-mediated phosphorylation. Endocr. Res. 26 (2000) 609-614
34. Paz C., Cornejo Maciel F., Maloberti P., Walsh L.P., Stocco D.M., and Podesta E.J. Protein tyrosine phosphatases are involved in LH/chorionic gonadotropin and 8Br-cAMP regulation of steroidogenesis and StAR protein levels in MA-10 Leydig cells. J. Endocrinol. 175 (2002) 793-801
35. Pearson G., Robinson F., Beers Gibson T., Xu B.E., Karandikar M., Berman K., and Cobb M.H. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 22 (2001) 153-183
36. Podesta E.J., Milani A., Steffen H., and Neher R. Steroidogenesis in isolated adrenocortical cells. Correlation with receptor-bound adenosine e 3′:5′-cyclic monophosphate. Biochem. J. 180 (1979) 355-363
37. Rae P.A., Gutmann N.S., Tsao J., and Schimmer B.P. Mutations in cyclic AMP-dependent protein kinase and corticotropin (ACTH)-sensitive adenylate cyclase affect adrenal steroidogenesis. Proc. Natl. Acad. Sci. U.S.A. 76 (1979) 1896-1900
38. Rocchi S., Gaillard I., van Obberghen E., Chambaz E.M., and Vilgrain I. Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: phosphorylation and activation by cAMP-dependent protein kinase. Biochem. J. 352 (2000) 483-490
39. Rohan P.J., Davis P., Moskaluk C.A., Kearns M., Krutzsch H., Siebenlist U., and Kelly K. PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase. Science 259 (1993) 1763-1766
40. Sala G.B., Hayashi K., Catt K.J., and Dufau M.L. Adrenocorticotropin action in isolated adrenal cells. The intermediate role of cyclic AMP in stimulation of corticosterone synthesis. J. Biol. Chem. 254 (1979) 3861-3865
41. Schimmer B.P. The 1994 Upjohn Award Lecture. Molecular and genetic approaches to the study of signal transduction in the adrenal cortex. Can. J. Physiol. Pharmacol. 73 (1995) 1097-1107
42. Schliess F., Heinrich S., and Haussinger D. Hyperosmotic induction of the mitogen-activated protein kinase phosphatase MKP-1 in H4IIE rat hepatoma cells. Arch. Biochem. Biophys. 351 (1998) 35-40
43. Sewer M.B., and Waterman M.R. Transcriptional complexes at the CYP17 CRS. Endocr. Res. 28 (2002) 551-558
44. Sewer M.B., and Waterman M.R. cAMP-dependent protein kinase enhances CYP17 transcription via MKP-1 activation in H295R human adrenocortical cells. J. Biol. Chem. 278 (2003) 8106-8111
45. Simpson E.R., Lund J., Ahlgren R., and Waterman M.R. Regulation by cyclic AMP of the genes encoding steroidogenic enzymes: when the light finally shines. Mol. Cell. Endocrinol. 70 (1990) C25-C28
46. Stocco D.M., and Clark B.J. Regulation of the acute production of steroids in steroidogenic cells. Endocr. Rev. 17 (1996) 221-244
47. Stoker A.W. Protein tyrosine phosphatases and signalling. J. Endocrinol. 185 (2005) 19-33
48. Sugawara T., Holt J.A., Kiriakidou M., and Strauss III J.F. Steroidogenic factor 1-dependent promoter activity of the human steroidogenic acute regulatory protein (StAR) gene. Biochemistry 35 (1996) 9052-9059
49. Theodosiou A., and Ashworth J.A. MAP kinase phosphatases. Genome Biol. 3 (2002) REVIEWS3009
50. Vilgrain I., Chinn A., Gaillard I., Chambaz E.M., and Feige J.J. Hormonal regulation of focal adhesions in bovine adrenocortical cells: induction of paxillin dephosphorylation by adrenocorticotropic hormone. Biochem. J. 332 (1998) 533-540
51. Walton K.M., and Dixon J.E. Protein tyrosine phosphatases. Annu. Rev. Biochem. 62 (1993) 101-120
52. Watanabe G., Pena P., Albanese C., Wilsbacher L.D., Young J.B., and Pestell R.G. Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo. J. Biol. Chem. 272 (1997) 20063-20069
53. Winnay J.N., and Hammer G.D. Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation. Mol. Endocrinol. 20 (2006) 147-166
54. Wong M., Krolczyk A.J., and Schimmer B.P. The causal relationship between mutations in cAMP-dependent protein kinase and the loss of adrenocorticotropin-regulated adrenocortical functions. Mol. Endocrinol. 6 (1992) 1614-1624