An adrenocorticotropin-regulated phosphoprotein intermediary in steroid synthesis is similar to an acyl-CoA thioesterase enzyme

European Journal of Biochemistry

Volumn 256, Issue 1, 1998, Pages 60-66

  Finkielstein, Carla ^a   Maloberti, Paula ^a   Mendez, Carlos F ^a   Paz, Cristina ^a   Cornejo Maciel, Fabiana ^a   Cymeryng, Cora ^a   Neuman, Isabel ^a   Dada, Laura ^a   Mele, Pablo G ^a   Solano, Angela ^a   Podestá, Ernesto J ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Acyl CoA thioesterase; Arachidonic acid; Hormone; Phosphorylation; Steroidogenesis

Indexed keywords

ARACHIDONIC ACID; COMPLEMENTARY DNA; CORTICOTROPIN; CYCLOHEXIMIDE; DACTINOMYCIN; DEXAMETHASONE; MESSENGER RNA; PALMITOYL COENZYME A HYDROLASE; PHOSPHOPROTEIN; PROTEIN KINASE; TRIACYLGLYCEROL LIPASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HUMAN; HUMAN TISSUE; LEYDIG CELL; MALE; MOLECULAR CLONING; NONHUMAN; OVARY; PLACENTA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROIDOGENESIS; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR CELL LINE; ZONA FASCICULATA;

ANIMALIA; MAMMALIA;

EID: 15644379252     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2560060.x     Document Type: Article

References (38)

1. Cooke, B. A., Lindh, M. L. & Janszen, F. H. A. (1976) Correlation of protein kinase activation and testosterone production after stimulation of Leydig cells with luteinizing hormone, Biochem. J. 160, 439-446.
2. Podestá, E. J., Dufau, M. L. & Catt, K. J. (1976) Characterization of two forms of cyclic 3′,5′-adenosine monophosphate-dependent protein kinase in rat testicular interstitial cells: hormonal activation and conversion to a single catalytic subunit in vitro, Mol. Cell. Endocrinol. 5, 109-122.
3. Dufau, M. L., Tsuruhara, T., Horner, K., Podestá, E. & Catt, K. (1977) Intermediate role of adenosine 3′:5′-cyclic monophosphate and protein kinase during gonadotropin-induced steroidogenesis in testicular interstitial cells, Proc. Natl Acad. Sci. USA 74, 3419-3423.
4. Podestá, E. J., Dufau, M. L., Solano, A. R. & Catt, K. J. (1978) Hormonal activation of protein kinase in isolated Leydig cells. Electrophoretic analysis of cyclic AMP receptors. J. Biol. Chem. 253, 8994-9001.
5. Rae, P. A., Gutmann, N. S., Tsao, J. & Schimmer, B. P. (1979) Mutations in cyclic AMP-dependent protein kinase and corticotropin (ACTH)-sensitive adenylate cyclase affect adrenal steroidogenesis, Proc. Natl Acad. Sci. USA 76, 1896-1900.
6. Sala, G., Hayoshi, K., Catt, K. & Dufau, M. (1979) Adrenocorticotropin action in isolated adrenal cells. The intermediate role of cyclic AMP in stimulation of corticosterone synthesis. J. Biol. Chem. 254, 3861-3865.
7. Podestá, E., Milani, A., Steffen, H. & Neher, R. (1979) Steroidogenesis in isolated adrenocortical cells. Correlation with receptor-bound adenosine 3′:5′-cyclic monophosphate, Biochem. J. 180, 355-363.
8. Kojima, I., Kojima, K. & Rasmussen, H. (1985) Possible role of phospholipase A2 action and arachidonic acid metabolism in angiotensin II-mediated aldosterone secretion. Endocrinology 117, 1057-1066.
9. Solano, A. R., Dada, L. A. & Podestá, E. J. (1988): Lipoxygenase products as common intermediates in cyclic AMP-dependent and -independent adrenal steroidogenesis in rats, J. Mol. Endocr. 1, 147-154.
10. Cooke, B. A., Dirami, G., Chaudry, L., Choi, M. S. K., Abayasekara, D. R. E. & Phipp, L. (1991) Release of arachidonic acid and the effects of corticosteroids on steroidogenesis in rat testis Leydig cells, J. Steroid Biochem. Mol. Biol. 40, 465-471.
11. Mele, P. G., Dada, L. A., Paz, C., Neuman, I., Cymeryng, C. B., Mendez, C. F., Finkielstein, C. V., Cornejo Maciel, F. & Podestá, E. J. (1997) Involvement of arachidonic acid and the lipoxygenase pathway in mediating luteinizing hormone-induced testosterone synthesis in rat Leydig cells, Endocr. Res. 23, 15-26.
12. Dix, C. J., Habberfield, A. D., Sullivan, M. H. & Cooke, B. A. (1984): Inhibition of steroid production in Leydig cells by non-steroidal anti-inflammatory and related compounds: evidence for the involvement of lipoxygenase products in steroidogenesis, Biochem. J. 219, 529-537.
13. Jones, D. B., Marante, D., Williams, C. & Edwards, C. R. W. (1987) Adrenal synthesis of corticosterone in response to ACTH in rats is influenced by leukotriene A4 and by lipoxygenase intermediates, J. Endocrinol. 112, 253-258.
14. Abayasekara, D. R. E., Band, A. M. & Cooke, B. A. (1990) Evidence for the involvement of phospholipase A2 in the regulation of luteinizing hormone-stimulated steroidogenesis in rat testis Leydig cells. Mol. Cell. Endocrinol. 70, 147-153.
15. Mikami, K., Omura, M., Tamura, Y. & Yoshida, S. (1990) Possible site of action of 5-hydroperoxyeicosatetraenoic acid derived from arachidonic acid in ACTH-stimulated steroidogenesis in rat adrenal glands. J. Endocrinol. 125, 89-96.
16. Lopez-Ruiz, M. P., Choi, M. S. K., Rose, M., West, A. P. & Cooke, B. A. (1992) Direct effect of arachidonic acid on protein kinase C and LH-stimulated steroidogenesis in rat Leydig cells; evidence for tonic inhibitory control of steroidogenesis by protein kinase C, Endocrinology 130, 1122-1130.
17. Dada, L. A., Paz, C., Mele, P. G., Solano, A. R., Cornejo Maciel, F. & Podestá, E. J. (1991) The cytosol as site of phosphorylation of the cyclic AMP-dependent protein kinase in adrenal steroidogenesis, J. Steroid Biochem. Mol. Biol. 39, 889-896.
18. Paz, C., Dada, L. A., Cornejo Maciel, M. F., Mele, P. G., Cymeryng, C. B., Neuman, I., Mendez, C. F., Finkielstein, C. V., Solano, A. R., Park, M., Fischer, W. H., Towbin, H., Scartazzini, R. & Podestá, E. J. (1994) Purification of a novel 43-kDa protein (p43) intermediary in the activation of steroidogenesis from rat adrenal gland, Eur. J. Biochem. 224, 709-716.
19. Finkielstein, C., Cymeryng, C., Paz, C., Neuman, I., Dada, L., Cornejo Maciel, F., Mele, P., Mendez, C. F., Maloberti, P., Solano, A., Schimmer, B. P. & Podestá, E. J. (1996) Characterization of the cDNA corresponding to a phosphoprotein (p43) intermediary in the action of ACTH, Endocr. Res. 22, 521-532.
20. Svensson, L. T., Engberg, S. T., Aoyama, T., Usuda, N., Alexson, S. E. H. & Hashimoto, T. (1998) Molecular cloning and characterization of a mitochondrial peroxisome proliferator-induced acyl-CoA thioesterase from rat liver, Biochem. J. 329, 601-608.
21. Camp, L. A. & Hofmann, S. L. (1993) Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras, J. Biol. Chem. 268, 22566-22574.
22. Dufau, M. L., Podestá, E. J. & Catt, K. J. (1975) Physical characteristics of the gonadotropin receptor-hormone complexes formed in vivo and in vitro, Proc. Natl Acad. Sci. USA 72, 1272-1275.
23. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular cloning: a laboratory manual, 2nd edn, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
24. Sanger, F., Nicklen, S. & Coulson, A. R. (1977) DNA sequencing with chain-terminating inhibitors, Proc. Natl Acad. Sci. USA 74, 5463-5467.
25. Southern, E. M. (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis, J. Mol. Biol. 98, 503-517.
26. Chomczynski, P. & Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal. Biochem. 162, 156-159.
27. Frohman, M. A., Dush, M. K. & Martin, G. R. (1988) Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer, Proc. Natl Acad. Sci. USA 85, 8998-9002.
28. Waterston, R., Martin, C., Craxton, M., Huynh, C., Coulson, A., Hillier, L., Durbin, R., Green, P., Shownkeen, R., Halloran, N., Metzstein, M., Hawkins, T., Wilson, R., Berks, M., Du, Z., Thomas, K., Thierry-Mieg, J. & Sulston, J. (1992) A survey of expressed genes in Caenorhabditis elegans, Nature Genet. 1, 114-123.
29. Warden, C. H., Mehrabian, M., He, K. Y., Yoon, M. Y., Diep, A., Xia, Y. R., Wen, P. Z., Svenson, K. L., Sparkes, R. S. & Lusis, A. J. (1993) Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse, Genomics 18, 295-307.
30. Kennelly, P. J. & Krebs, E. G. (1991) Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases, J. Biol. Chem. 266, 15555-15558.
31. Witkowski, A., Witkowska, H. E. & Smith, S. (1994) Reengineering the specificity of a serine active-site enzyme, Two active-site mutations convert a hydrolase to a transferase, J. Biol. Chem. 269, 379-383.
32. Svensson, L. T., Alexson, S. E. H. & Hiltunen, K. (1995) Very long chain and long chain acyl-CoA thioesterases in rat liver mitochondria, J. Biol. Chem. 270, 12 177-12 183.
33. Engberg, S. T., Aoyama, T., Alexson, S. E. H., Hashimoto, T. & Svensson, L. T. (1997) Peroxisome proliferator-induced acyl-CoA thioesterase from rat liver cytosol: molecular cloning and functional expression in Chinese hamster ovary cells, Biochem. J. 323, 525-531.
34. Raj, N. B. K. & Pitha, P. M. (1981) Analysis of Interferon mRNA in human fibroblast cells induced to produce interferon. Proc. Natl Acad. Sci. USA 78, 7426-7430.
35. Garren, L. D., Ney, R. L. & Davis, W. W. (1965) Studies on the role of protein synthesis in the regulation of corticosterone production by ACTH in vivo. Proc. Natl Acad. Sci. USA 53, 1443-1450.
36. Cymeryng, C. B., Paz, C., Dada, L., Cornejo Maciel, F., Neuman, M. I., Mele, P. G., Finkielstein, C., Solano, A. R., Mendez, C. F., Park, M., Fischer, W., Towbin, H., Scartazzini, R. & Podestá, E. J. (1995) ACTH-dependent proteolytic activity of a novel phosphoprotein (p43) intermediary in the activation of phosphoplipase A2 and steroidogenesis, Endocr. Res. 21, 281-288.
37. Svensson, L. T., Wilcke, M. & Alexson, S. E. H. (1995) Peroxisome proliferators differentially regulate long-chain acyl-CoA thioesterases in rat liver, Eur. J. Biochem. 230, 813-820.
38. Neher, R., Milani, A., Solano, A. R. & Podestá, E. J. (1982) Compartmentalization of corticotropin-dependent steroidogenic factors in adrenal cortex: evidence for a post-translational cascade in stimulation of cholesterol side chain split, Proc. Natl Acad. Sci. USA 79, 1727-1731.