Mislocalization of prelamin A Tyr646Phe mutant to the nuclear pore complex in human embryonic kidney 293 cells

Biochemical and Biophysical Research Communications

Volumn 355, Issue 1, 2007, Pages 78-84

  Pan, Yong ^a   Garg, Abhimanyu ^a   Agarwal, Anil K ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

CaaX motif protein; Farnesyl transferase inhibitors; Lamin A C; Lipodystrophy; Nuclear pore complex protein; Prenylation; Progeria; Zinc metalloprotease (ZMPSTE24)

Indexed keywords

COMPLEMENTARY DNA; LAMIN A; LAMIN C; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; NUCLEOPORIN; NUCLEOPORIN 53; NUCLEOPORIN 98; PRELAMIN A; PROTEIN FARNESYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; EMBRYO; ENZYME INHIBITION; GENE; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; LIPODYSTROPHY; LMNA GENE; MOLECULAR CLONING; MUTANT; NUCLEAR PORE COMPLEX; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; WESTERN BLOTTING;

AMINO ACID SUBSTITUTION; CELL LINE; CLONING, MOLECULAR; HUMANS; KIDNEY; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PORE; NUCLEAR PROTEINS; PROTEIN PRECURSORS; RECOMBINANT PROTEINS; RESTRICTION MAPPING; TRANSFECTION;

EID: 33847034347     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.01.116     Document Type: Article

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