Hypothyroidism and myxedema coma

Compendium: Continuing Education For Veterinarians

Volumn 29, Issue 1, 2007, Pages 19-32

  Finora, Kevin ^a,b   Greco, Deborah ^a  

^a ANIMAL MEDICAL CENTER   (United States)

^b Veterinary Emergency Clinic   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

THYROTROPIN; THYROXINE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CAT; CAT DISEASE; DOG; DOG DISEASE; HYPOTHYROIDISM; METHODOLOGY; MYXEDEMA; THYROID FUNCTION TEST;

ANIMALS; CAT DISEASES; CATS; DOG DISEASES; DOGS; HYPOTHYROIDISM; MYXEDEMA; THYROID FUNCTION TESTS; THYROTROPIN; THYROXINE;

CANIS FAMILIARIS;

EID: 33847033029     PISSN: 19408307     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (74)

1. Feldman ED, Nelson RW (eds): Canine and Feline Endocrinology and Reproduction. St. Louis, Elsevier Saunders, 2004, pp 86-151.
2. Scott-Moncrieff JCR, Guptill-Yoran L: Hypothyroidism, in Ettinger SJ, Feldman EC (eds): Textbook of Veterinary Internal Medicine. St. Louis, Elsevier Saunders, 2005, pp 1535-1544.
3. Guyton AC, Hall JE (eds): Textbook of Medical Physiology. St. Louis, Elsevier Saunders, 2005, pp 858-869.
4. Cunningham JG (ed): Textbook of Veterinary Physiology. New York, WB Saunders, 2002, pp 341-372.
5. Gulikers KP, Panciera DL: Influence of various medications on canine thyroid function. Campend Contin Educ Pract Vet 24(7):511-521, 2002.
6. Gosselin SJ, Capen CC, Martin SL: Histologic und ultrastructural evaluation of thyroid lesions associated with hypothyroidism in dogs. Vet Parbol 18(3): 299-309, 1981.
7. Kemppainen RJ, Clark TP: Etiopathogenesis of canine hypothyroidism. Vet Clin North Am Small Anim Pract 24(3):467-476, 1994.
8. Tews MC, Shah SM, Gossain VV: Hypothyroidism: Mimicker of common complaints. Emerg Med Clin North Am 23(3):649-667, 2005.
9. Nachreiner F, Refsal KR, Graham PA, et al: Prevalence of autoantibodics to thyroglobulin in dogs with nonthyroidal illness. Am J Vet Res 59(8):951-955, 1998.
10. Patzl M, Mostl E: Determination of autoantibodics to thyroglobulin, thyroxine and triiodothyronine in canine scrum. J Vet Mid A Physiol Pathol Clin Med 50(2):72-78, 2003.
11. Rajatanavin R, Fang SL, Pino S, et al: Thyroid hormone antibodies and Hashimoto's thyroiditis in mongrel dogs. Endocrinology 124(5):2535-2540, 1989.
12. Chastain CB, Young DW, Kemppainen RJ: Anti-triiudothyronine antibodies associated with hypothyroidism and lymphocytic thyroiditis in a dog. JAVMA 194(4):531-534, 1989.
13. Scott-Moncrieff JC, Azcona-Olivera J, Glickman NW, et al: Evaluation of antithyroglobulin antibodies after routine vaccination in pet and research dogs. JAVMA 221(4):515-521, 2002.
14. Young DW, Sartin JL, Kemppainen RJ: Abnormal canine triiodothyronine- binding factor characterized as a possible triiodothyronine autoantibody. Am J Vet Res 46(6):1346-1350, 1985.
15. Nachreiner RF, Refsal KR, Graham PA, et al: Prevalence of serum thyroid hormone autoantibodies in dogs with clinical signs of hypothyroidism. JAVMA 220(4):466-471, 2002.
16. Benjamin SA, Stephens LC, Hamilton BF, et al: Associations between lymphocytic thyroiditis, hypothyroidism, and thyroid ncoplasia in beagles. Vet Pathol 33(5):486-494, 1996.
17. Meric SM, Rubin SI: Serum thyroxine concentrations following fixed-dose radioactive iodine treatment in hyperthyroid cats: 62 cases (1986-1989). JAVMA 197(5):621-623, 1990.
18. Daminet S, Ferguson DC: Influence of drugs on thyroid function in dogs, J Vet Intern Med 17(4):463-472, 2003.
19. Meeking SA: Thyroid disorders in the geriatric patient. Vet Clin North Am Small Anim Pract 35(3):635-653, 2005.
20. Fyfe JC, Kampschmidt K, Dang V, et al: Congenital hypothyroidism with goiter in toy fox terriers., J Vet Intern Med 17(1):50-57, 2003.
21. Greco DS, Feldman EC, Peterson ME, et al: Congenital hypothyroid dwarfism in a family of giant schnauzers. J Vet Intern Med 5(2):57-65, 1991.
22. Jones BR, Gruffydd-Jones TJ, Sparkes AH, et al: Preliminary studies on congenital hypothyroidism in a family of Abyssinian cats. Vet Rec 131(7):145-148, 1992.
23. Panciera DL: Conditions associated with canine hypothyroidism. Vet Clin North Am Small Anim Pract 31(5):935-950, 2001.
24. Rosychuk RAW: Dermatologie manifestations of canine hypothyroidism and the usefulness of dermatohistopathology in establishing a diagnosis. Canine Pwr22(l):2S-26,1997.
25. Credille KM, Slater MR, Moriello KA, et al: The effects of thyroid hormones on the skin of beagle dogs. J Vtt Intern Med 15(6):539-546, 2001.
26. Chen Y: Effect of thyroxine on the immune response of mice in vivo and in vitro. Immunol Commun 9(3):260-276, 1980.
27. Bichsel P, Jacobs G, Oliver JE: Neurologic manifestations associated with hypothyroidism in four dogs. JAVMA 192(12):1745-1747, 1988.
28. Beghi E, Delodovici ML, Bogliun G, et al: Hypothyroidism and polyncuropathy. J Neurol Neurosurg Psychiatry 52(12):1420-1423, 1989.
29. Gaynor AR, Shofer FS, Washabau RJ: Risk factors for Acquired megacsophagus gus in dogs. JAMVA 211(11):1406-1412, 1997.
30. Greco DS, Rosychuk RAW, Ogilvie GK, et al; The effect of levothyroxine treatment on resting energy expenditure of hyputhyroid dogs, J Vet Intern Med 12(1);7-10, 1998.
31. Panciera DL: A retrospective study of 66 cases of canine hypothyroidism (1987-1992). JAVMA 204(5):761-767, 1994.
32. Fliers E, Wiersinga WM: Myxcdema coma. Rev Endso Metab Disord 4(2);137-141, 2003.
33. Wall CR: Myxedema coma: Diagnosis and treatment. Am Film Physician 62(11):2485S-2490, 2000.
34. Johnson C, Olivier NB, Nachreiner R, et al: Effect of -induced hypothyroidism on indices of reproductive function in adult male dogs. J Vet Intern Med 13(2):104-110, 1999.
35. Beale KM, Bloomberg MS, Van Gilder J, et al: Correlation of racing and reproductive performance in greyhounds with response to thyroid function testing. JAAHA 28(3):263-269, 1992.
36. Hawthorn MH, Gengo P, Wei XY: Effect of thyroid status on beta-adrenoceptors and calcium channels in rat cardiac and vascular tissue. Naunyn Schmiededbergs Arch Pharmacol 337(5):539-544, 1988.
37. Danzi S, Klein I: Thyroid hormone and the cardiovascular system. Minerva Endocrinol 29(3):139-150, 2004.
38. Dixon RM, Reid SWJ, Mooney CT: Epidemiological, clinical, haematological and biochemical characteristics of canine hypothyroidism. Vet Res 145(17):481-487, 1999.
39. Hess RS, Kass PH, Van Winkle TJ: Association between diabetes mellitus, hypothyroidism or hyperadrenocorticism, and atherosclerosis in dogs. J Vet Intern Med 17(4):489-494, 2003.
40. Liu SK, Tilley LP, Tappe JP, et al: Clinical and pathologic findings in dogs with atherosclerosis; 21 cases (1970-1983). JAVMA 189(2):227-232, 1986.
41. Sainteny F, Larras-Regard E, Frindel F: Thyroid hormones induce hematopoietic pluripotent stem cell differentiation toward erythropoiesis through the production of pluripoietin-like factors. Exp Cell Res 187(1):174-176, 1990.
42. Dixon RM: Canine hypothyroidism, in Mooney CT, Peterson ME (eds): BSAVA Manual of Canine and Feline Endocrinology. Gloucester, British Small Animal Veterinary Association, 2004, pp 76-94.
43. Kemppainen RJ, Behrend EN: Diagnosis of canine hypothyroidism perspectives from a testing laboratory. Vet Clin North Am Small Anim Pract 31(5):951-962, 2001.
44. Lurye JC, Behrend EN, Kemppainen RJ: Evaluation of an in-house enzymelinked immunosorbent assay for quantitative measurement of serum total thyroxine concentration in dogs and cat. JAVMA 221(2):243-249, 2002.
45. Rayalam S, Eizenstat LD, Davis RR, et al: Expression and purification of feline thyrotropin (fTSH): Immunological detection and bioactivity of heterodimeric and yoked glycoproteins. Domest Anim Endocrinol 30(3):185-202, 2006.
46. Peterson ME, Melian C, Nichols R: Measurement of serum total thyroxine, triiodothyronine, free thyroxine, and thyrotropin concentrations for diagnosis of hypothyroidism in dogs. JAVMA 211(11):1396-1402, 1997.
47. Dixon RM, Mooney CT: Evaluation of serum free thyroxine and thyrotropin concentrations in the diagnosis of canine hypothyroidism. J Small Anim Pract 40(2):72-78, 1999.
48. Ferguson DC, Peterson ME: Serum free and total iodothyronine concentra tions in dogs with hyperadrenocorticism. Am J Vet Res 53(9):1636-1640, 1992
49. Kantrowitz LB, Peterson ME, Trepanier LA, et al: Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in epileptic dogs treated with anticonvulsants. JAVMA 214(12):1804-1808, 1999.
50. Schachter S, Nelson RW, Scott-Moncrieff C, et al: Comparison of serum-free thyroxine concentrations determined by standard equilibrium dialysis, modified equilibrium dialysis, and 5 radioimmunoassays in dogs. J Vet Intern Med 8(3):259-264, 2004.
51. Dixon RM, Mooney CT: Canine serum thyroglobulin autoantibodies in health, hypothyroidism and non-thyroidal illness. Rss Vet Sci 66(3):243-246, 1999.
52. Panciera DL: Thyroid function tests: What do they really tell us? J Vet Intern Med 15(1):86-88, 2001.
53. Kantrowitz LB, Peterson ME, Melian C, et al: Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in dogs with nonthyroidal disease. JAVMA 219(6):765-769, 2001.
54. Sauve F, Paradis M: Use of recombinant human thyroid-stimulating hormone for thyrotropin stimulation test in euthyroid dogs. Can Vet J 41(March):215-219, 2000.
55. Stegeman JR, Graham PA, Hauptman JG: Use of recombinant human thyroid-stimulating hormone for thyrotropin-stimulation testing of euthyroid cats. Am J Vet Res 64(2): 149-152, 2003.
56. Reese S, Breyer U, Deeg C, et al: Thyroid sonography as an effective tool to discriminate between euthyroid sick and hypothyroid dogs. J Vet Intern Med 19(4):491-498, 2005.
57. Bromel C, Pollard RE, Kass PH, et al: Ultrasonographic evaluation of the thyroid gland in healthy, hypothyroid, and euthyroid golden retrievers with nonthyroidal illness. J Vet Intern Med 19(4):499-506, 2005.
58. Williamson NL, Frank LA, Hnilica KA: Effects of short-term trimethoprim-sulfamethoxazole administration on thyroid function in dogs. JAVMA 221(6):802-806, 2002.
59. Franks LA, Hnilica KA, May ER, et al: Effects of sulfamethoxazole- trimethoprim on thyroid function in dogs. Am J Vet Res 66(2):256-259, 2005.
60. Torres SM, McKeever PJ, Johnston SD: Effect of oral administration of prednisolone on thyroid function in dogs. Am J Vet Res 52(3):416-421, 1991.
61. Daminet S, Paradis M, Refsal KR, et al: Short-term influence of prednisone and phenobarbital on thyroid function in euthyroid dogs. Can Vet J 40(6):411-415, 1999.
62. Muller PB, Wolfsheimer KJ, Taboada J, et al: Effects of long-term phenobar-bird treatment on the thyroid and adrenal axis and adrenal function tests in dogs. J Vet Intern Med 14(2):157-164, 2000.
63. Gieger TL, Hosgood G, Taboado J, et al: Thyroid function and serum hepatic enzyme activity in dogs after phenobarbital administration. J Vet Intern Med 14(3):277-281, 2000.
64. Gulikers KP, Panciera DL: Evaluation of the effects of clomipramine on canine thyroid function tests. J Vet Intern Med 17(1):44-49, 2003.
65. Daminet S, Croubels S, Duchateau L, et al: Influence of acetylsalicylic acid and ketoprofen on canine thyroid function tests. Vet J 166(3):224-232, 2003.
66. Evason MD, Carr AP, Taylor SM, et al: Alterations in thyroid hormone concentrations in healthy sled dogs before and after athletic conditioning. Am J Vet Res 65(3):333-337, 2004.
67. Lee JA, Hinchcliff KW, Piercy RJ, et al: Effects of racing and nontraining on plasma thyroid hormone concentrations in sled dogs. JAVMA 224(2):226-231, 2004.
68. Panciera DL, Hinchcliff KW, Olson J, et al: Plasma thyroid hormone concentrations in dogs competing in a long-distance sled dog race. J Vet Intern Med 17(4):593-596, 2003.
69. Hill RC, Fox LE, Lewis DD, et al: Effects of racing and training on serum thyroid hormone concentrations in racing greyhounds. Am J Vet Res 62(12):1969-1972, 2001.
70. Gaughan KR, Bruyette DS: Thyroid function testing in greyhounds. Am J Vet Res 62(7):1130-1133, 2001.
71. Davies TF: Thyroid hormone replacement in dogs. Thyroid 11(4):299, 2001.
72. Dixon RM, Reid SWJ, Mooney CT: Treatment and therapeutic monitoring of canine hypothyroidism. J Small Anim Pract 43(8):334-340, 2002.
73. Atkinson K, Aubert I: Myxedema coma leading to respiratory depression in a dog. Can Vet J 45(4):318-320, 2004.
74. Henik RA, Dixon RM: Intravenous administration of levothyroxine for treatment of suspected myxedema coma complicated by severe hypothermia in a dog. JAVMA 216(5):713-717, 2000.