-
1
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
-
Palella, F.J. Jr., Delaney, K.M., Moorman, A.C. et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998, 338: 853-60.
-
(1998)
N Engl J Med
, vol.338
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
-
2
-
-
0030923798
-
Impact of combination therapy for HIV infection on inpatient census
-
Torres, R.A., Barr, M. Impact of combination therapy for HIV infection on inpatient census. N Engl J Med 1997, 336: 1531-2.
-
(1997)
N Engl J Med
, vol.336
, pp. 1531-1532
-
-
Torres, R.A.1
Barr, M.2
-
3
-
-
0035423963
-
Reconstitution of CD4p T lymphocytes in HIV-infected individuals following antiretroviral therapy
-
Carcelain, G., Debre, P., Autran, B. Reconstitution of CD4p T lymphocytes in HIV-infected individuals following antiretroviral therapy. Curr Opin Immunol 2001, 13: 483-8.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 483-488
-
-
Carcelain, G.1
Debre, P.2
Autran, B.3
-
4
-
-
0037045011
-
Rapid reconstitution of humoral immunity against cytomegalovirus but not HIV following highly active antiretroviral therapy
-
Deayton, J.R., Sabin, C.A., Britt, W.B. et al. Rapid reconstitution of humoral immunity against cytomegalovirus but not HIV following highly active antiretroviral therapy. AIDS 2002, 16: 2129-35.
-
(2002)
AIDS
, vol.16
, pp. 2129-2135
-
-
Deayton, J.R.1
Sabin, C.A.2
Britt, W.B.3
-
5
-
-
0033010070
-
Immunopathology as a result of highly active antiretroviral therapy in HIV-1-infected patients
-
Foudraine, N.A., Hovenkamp, E., Notermans, D.W. et al. Immunopathology as a result of highly active antiretroviral therapy in HIV-1-infected patients. AIDS 1999, 13: 177-84.
-
(1999)
AIDS
, vol.13
, pp. 177-184
-
-
Foudraine, N.A.1
Hovenkamp, E.2
Notermans, D.W.3
-
6
-
-
0037045011
-
Rapid reconstitution of humoral immunity against cytomegalovirus but not HIV following highly active antiretroviral therapy
-
Deayton, J.R., Sabin, C.A., Britt, W.B. et al. Rapid reconstitution of humoral immunity against cytomegalovirus but not HIV following highly active antiretroviral therapy. AIDS 2002, 16: 2129-35.
-
(2002)
AIDS
, vol.16
, pp. 2129-2135
-
-
Deayton, J.R.1
Sabin, C.A.2
Britt, W.B.3
-
7
-
-
0032941595
-
HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
-
Pitcher, C.J., Quittner, C., Peterson, D.M. et al. HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression. Nat Med 1999, 5: 518-25.
-
(1999)
Nat Med
, vol.5
, pp. 518-525
-
-
Pitcher, C.J.1
Quittner, C.2
Peterson, D.M.3
-
8
-
-
7144229335
-
Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease
-
Piketty, C., Castiel, P., Belec, L. et al. Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease. AIDS 1998, 12: 745-50.
-
(1998)
AIDS
, vol.12
, pp. 745-750
-
-
Piketty, C.1
Castiel, P.2
Belec, L.3
-
9
-
-
0033984368
-
Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic response
-
Connick, E., Lederman, M., Kotzin, B. et al. Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic response. J Infect Dis 2000, 181: 358-63.
-
(2000)
J Infect Dis
, vol.181
, pp. 358-363
-
-
Connick, E.1
Lederman, M.2
Kotzin, B.3
-
10
-
-
0034641205
-
Immune restoration with antiretroviral therapies: Implications for clinical management
-
Lederman, M.M., Valdez, H. Immune restoration with antiretroviral therapies: Implications for clinical management. JAMA 2000, 284: 223-8.
-
(2000)
JAMA
, vol.284
, pp. 223-228
-
-
Lederman, M.M.1
Valdez, H.2
-
11
-
-
0020565302
-
Molecular characterization of interleukin 2
-
Watson, J.D., Gillis, D.Y., Mochizuki, S. Molecular characterization of interleukin 2. Fed Proc 1983, 42: 2747-52.
-
(1983)
Fed Proc
, vol.42
, pp. 2747-2752
-
-
Watson, J.D.1
Gillis, D.Y.2
Mochizuki, S.3
-
12
-
-
0023907493
-
Interleukin-2: Inception, impact, and implications
-
Smith, K.A. Interleukin-2: Inception, impact, and implications. Science 1988, 240: 1169-76.
-
(1988)
Science
, vol.240
, pp. 1169-1176
-
-
Smith, K.A.1
-
13
-
-
0020580976
-
Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets
-
Kasahara, T., Hooks, J.J., Dougherty, S.F., Oppenheim, J.J. Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets. J Immunol 1983, 130: 1784-9.
-
(1983)
J Immunol
, vol.130
, pp. 1784-1789
-
-
Kasahara, T.1
Hooks, J.J.2
Dougherty, S.F.3
Oppenheim, J.J.4
-
14
-
-
0020578618
-
Inter-leukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndrome
-
Rook, A.H., Masur, H., Lane, H.C. et al. Inter-leukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndrome. J Clin Invest 1983, 72: 398-403.
-
(1983)
J Clin Invest
, vol.72
, pp. 398-403
-
-
Rook, A.H.1
Masur, H.2
Lane, H.C.3
-
15
-
-
0021925085
-
Interleukin 2 enhances the natural killer cell activity of acquired immunodeficiency syndrome patients through a gamma-interferon-independent mechanism
-
Rook, A.H., Masur, H., Lane, H.C. et al. Interleukin 2 enhances the natural killer cell activity of acquired immunodeficiency syndrome patients through a gamma-interferon-independent mechanism. J Immunol 1985, 134: 1503-7.
-
(1985)
J Immunol
, vol.134
, pp. 1503-1507
-
-
Rook, A.H.1
Masur, H.2
Lane, H.C.3
-
16
-
-
0036677041
-
Molecular virology and immunology of HIV infection
-
Chinen, J., Shearer, W.T. Molecular virology and immunology of HIV infection. J Allergy Clin Immunol 2002, 110: 189-98.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 189-198
-
-
Chinen, J.1
Shearer, W.T.2
-
17
-
-
0022314094
-
Immunologic abnormalities in the acquired immunodeficiency syndrome
-
Lane, H.C., Fauci, A.S. Immunologic abnormalities in the acquired immunodeficiency syndrome. Annu Rev Immunol 1985, 3: 477-500.
-
(1985)
Annu Rev Immunol
, vol.3
, pp. 477-500
-
-
Lane, H.C.1
Fauci, A.S.2
-
18
-
-
33846975570
-
Immunopathogenesis of the acquired immunodeficiency restored by antiviral or immune-based therapies
-
Bowen, D.L., Lane, H.C., Fauci, A.S. Immunopathogenesis of the acquired immunodeficiency restored by antiviral or immune-based therapies. Nat Med 1997, 3: 533-40.
-
(1997)
Nat Med
, vol.3
, pp. 533-540
-
-
Bowen, D.L.1
Lane, H.C.2
Fauci, A.S.3
-
19
-
-
16944367032
-
HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies
-
Connors, M., Kovacs, J.A., Krevat, S. et al. HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies. Nat Med 1997, 3: 533-40.
-
(1997)
Nat Med
, vol.3
, pp. 533-540
-
-
Connors, M.1
Kovacs, J.A.2
Krevat, S.3
-
20
-
-
0022355372
-
Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome
-
Murray, H.W., Weite, K., Jacobs, J.L., Rubin, B.Y., Mertelsmann, R., Roberts, R.B. Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome. J Clin Invest 1985, 76: 1959-64.
-
(1985)
J Clin Invest
, vol.76
, pp. 1959-1964
-
-
Murray, H.W.1
Weite, K.2
Jacobs, J.L.3
Rubin, B.Y.4
Mertelsmann, R.5
Roberts, R.B.6
-
21
-
-
0026675818
-
Heterogeneous effects of exogenous IL-2 on HIV-specific cell-mediated immunity (CMI)
-
Bell, S.J., Cooper, D.A., Kemp, B.E., Doherty, R.R., Penny, R. Heterogeneous effects of exogenous IL-2 on HIV-specific cell-mediated immunity (CMI). Clin Exp Immunol 1992, 90: 6-12.
-
(1992)
Clin Exp Immunol
, vol.90
, pp. 6-12
-
-
Bell, S.J.1
Cooper, D.A.2
Kemp, B.E.3
Doherty, R.R.4
Penny, R.5
-
22
-
-
23644439060
-
Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients
-
Kovacs, J.A., Lempicki, R.A., Sidorov, I.A. et al. Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients. J Clin Invest 2005, 115: 2139-48.
-
(2005)
J Clin Invest
, vol.115
, pp. 2139-2148
-
-
Kovacs, J.A.1
Lempicki, R.A.2
Sidorov, I.A.3
-
23
-
-
0029923736
-
Interleukin-2 and human immunodeficiency virus infection: Pathogenic mechanisms and potential for immunologic enhancement
-
Kinter, A., Fauci, A.S. Interleukin-2 and human immunodeficiency virus infection: Pathogenic mechanisms and potential for immunologic enhancement. Immunol Res 1996, 15: 1-15.
-
(1996)
Immunol Res
, vol.15
, pp. 1-15
-
-
Kinter, A.1
Fauci, A.S.2
-
24
-
-
0028875759
-
Interleukin 2 induces CD8+ T cell-mediated suppression of human immunodeficiency virus replication in CD4+ T cells and this effect overrides its ability to stimulate virus expression
-
Kinter, A.L., Bende, S.M., Hardy, E.C., Jackson, R., Fauci, A.S. Interleukin 2 induces CD8+ T cell-mediated suppression of human immunodeficiency virus replication in CD4+ T cells and this effect overrides its ability to stimulate virus expression. Proc Natl Acad Sci USA 1995, 92: 10985-9.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10985-10989
-
-
Kinter, A.L.1
Bende, S.M.2
Hardy, E.C.3
Jackson, R.4
Fauci, A.S.5
-
25
-
-
0023933696
-
Effects of interleukin 2 and large envelope glycoprotein (gp 120) of human immunodeficiency virus (HIV) on lymphocyte proliferative responses to cytomegalovirus
-
Krowka, J., Stites, D., Mills, J. et al. Effects of interleukin 2 and large envelope glycoprotein (gp 120) of human immunodeficiency virus (HIV) on lymphocyte proliferative responses to cytomegalovirus. Clin Exp Immunol 1988, 72: 179-85.
-
(1988)
Clin Exp Immunol
, vol.72
, pp. 179-185
-
-
Krowka, J.1
Stites, D.2
Mills, J.3
-
26
-
-
0030293533
-
IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection. Correlation with its ability to block culture-induced down-modulation of Bcl-2
-
Adachi, Y., Oyaizu, N., Than, S., McCloskey, T.W., Pahwa, S. IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection. Correlation with its ability to block culture-induced down-modulation of Bcl-2. J Immunol 1996, 157: 4184-93.
-
(1996)
J Immunol
, vol.157
, pp. 4184-4193
-
-
Adachi, Y.1
Oyaizu, N.2
Than, S.3
McCloskey, T.W.4
Pahwa, S.5
-
27
-
-
22144470799
-
In vivo expansion of CD4+CD45RO-CD25+T cells expressing foxP3 in IL-2-treated HIV-infected patients
-
Sereti, I., Imamichi, H., Natarajan, V. et al. In vivo expansion of CD4+CD45RO-CD25+T cells expressing foxP3 in IL-2-treated HIV-infected patients. J Clin Invest 2005, 115: 1839-47.
-
(2005)
J Clin Invest
, vol.115
, pp. 1839-1847
-
-
Sereti, I.1
Imamichi, H.2
Natarajan, V.3
-
28
-
-
3242773778
-
IL-2-induced CD4+T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation
-
Sereti, I., Anthony, K.B., Martinez-Wilson, H. et al. IL-2-induced CD4+T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation. Blood 2004, 104: 775-80.
-
(2004)
Blood
, vol.104
, pp. 775-780
-
-
Sereti, I.1
Anthony, K.B.2
Martinez-Wilson, H.3
-
29
-
-
0021999943
-
Preliminary clinical observations with recombinant interleukin-2 in patients with AIDS or LAS
-
Kern, P., Toy, J., Dietrich, M. Preliminary clinical observations with recombinant interleukin-2 in patients with AIDS or LAS. Blut 1985, 50: 1-6.
-
(1985)
Blut
, vol.50
, pp. 1-6
-
-
Kern, P.1
Toy, J.2
Dietrich, M.3
-
30
-
-
0022922250
-
Effects of systemic in vivo interleukin-2 (IL-2) reconstitution in patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) on phenotypes and functions of peripheral blood mononuclear cells (PBMC)
-
Ernst, M., Kern, P., Flad, H.D., Ulmer, A.J. Effects of systemic in vivo interleukin-2 (IL-2) reconstitution in patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) on phenotypes and functions of peripheral blood mononuclear cells (PBMC). J Clin Immunol 1986; 6: 170-81.
-
(1986)
J Clin Immunol
, vol.6
, pp. 170-181
-
-
Ernst, M.1
Kern, P.2
Flad, H.D.3
Ulmer, A.J.4
-
31
-
-
0023575616
-
Therapy of acquired immune deficiency syndrome with recombinant interleukin-2
-
Volberding, P., Moody, D.J., Beardslee, D., Bradley, E.C., Wofsy, C.B. Therapy of acquired immune deficiency syndrome with recombinant interleukin-2. AIDS Res Hum Retroviruses 1987, 3: 115-24.
-
(1987)
AIDS Res Hum Retroviruses
, vol.3
, pp. 115-124
-
-
Volberding, P.1
Moody, D.J.2
Beardslee, D.3
Bradley, E.C.4
Wofsy, C.B.5
-
32
-
-
0026097439
-
Safety and effects of interleukin 2 plus zidovudine in asymptomatic individuals infected with human immunodeficiency virus
-
Schwartz, D.H., Skowron, G., Merigan, T.C. Safety and effects of interleukin 2 plus zidovudine in asymptomatic individuals infected with human immunodeficiency virus. J Acquir Immune Defic Syndr 1991, 4: 11-23.
-
(1991)
J Acquir Immune Defic Syndr
, vol.4
, pp. 11-23
-
-
Schwartz, D.H.1
Skowron, G.2
Merigan, T.C.3
-
33
-
-
0031741466
-
Pharmacokinetic modeling of recombinant interleukin-2 in patients with human immunodeficiency virus infection
-
Piscitelli, S.C., Forrest, A., Vogel, S. et al. Pharmacokinetic modeling of recombinant interleukin-2 in patients with human immunodeficiency virus infection. Clin Pharmacol Ther 1998, 64: 492-8.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 492-498
-
-
Piscitelli, S.C.1
Forrest, A.2
Vogel, S.3
-
34
-
-
0345700836
-
A randomized controlled trial evaluating the efficacy and safety of intermittent 3-, 4-, and 5-day cycles of intravenous recombinant human interleukin-2 combined with antiretroviral therapy (ART) versus ART alone in HIV-seropositive patients with 100-300 CD4+ T cells
-
de Boer, A.W., Markowitz, N., Lane, H.C. et al. A randomized controlled trial evaluating the efficacy and safety of intermittent 3-, 4-, and 5-day cycles of intravenous recombinant human interleukin-2 combined with antiretroviral therapy (ART) versus ART alone in HIV-seropositive patients with 100-300 CD4+ T cells. Clin Immunol 2003, 106: 188-96.
-
(2003)
Clin Immunol
, vol.106
, pp. 188-196
-
-
de Boer, A.W.1
Markowitz, N.2
Lane, H.C.3
-
35
-
-
0028912032
-
Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study
-
Kovacs, J.A., Baseler, M., Dewar, R.J. et al. Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study. N Eng J Med 1995, 332: 567-75.
-
(1995)
N Eng J Med
, vol.332
, pp. 567-575
-
-
Kovacs, J.A.1
Baseler, M.2
Dewar, R.J.3
-
36
-
-
0013610170
-
Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus
-
Kovacs, U.A., Vogel, S., Albert, J.M. et al. Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus. N Eng J Med 1996, 335: 1350-6.
-
(1996)
N Eng J Med
, vol.335
, pp. 1350-1356
-
-
Kovacs, U.A.1
Vogel, S.2
Albert, J.M.3
-
37
-
-
0031680651
-
Outpatient continuous intravenous interleukin-2 or subcutaneous, polyethylene glycol-modified interleukin-2 in human immunodeficiency virus-infected patients: A randomized, controlled, multicenter study
-
for the Australian IL-2 Study Group
-
Carr, A., Emery, S., Lloyd, A. et al.; for the Australian IL-2 Study Group. Outpatient continuous intravenous interleukin-2 or subcutaneous, polyethylene glycol-modified interleukin-2 in human immunodeficiency virus-infected patients: A randomized, controlled, multicenter study. J Infect Dis 1998, 178: 992-9.
-
(1998)
J Infect Dis
, vol.178
, pp. 992-999
-
-
Carr, A.1
Emery, S.2
Lloyd, A.3
-
38
-
-
0033526641
-
Comparison of subcutaneous and intravenous interleukin-2 in asymptomatic HIV-1 infection: A randomized controlled trial. ANRS 048 study group
-
Levy, Y., Capitant, C., Houhou, S. et al. Comparison of subcutaneous and intravenous interleukin-2 in asymptomatic HIV-1 infection: A randomized controlled trial. ANRS 048 study group. Lancet 1999, 353: 1923-9.
-
(1999)
Lancet
, vol.353
, pp. 1923-1929
-
-
Levy, Y.1
Capitant, C.2
Houhou, S.3
-
39
-
-
0033836422
-
Pooled analysis of 3 randomized, controlled trials of interleukin-2 therapy in adult human immunodeficiency virus type 1 disease
-
Emery, S., Capra, W.B., Cooper, D.A. et al. Pooled analysis of 3 randomized, controlled trials of interleukin-2 therapy in adult human immunodeficiency virus type 1 disease. J Infect Dis 2000, 182: 428-34.
-
(2000)
J Infect Dis
, vol.182
, pp. 428-434
-
-
Emery, S.1
Capra, W.B.2
Cooper, D.A.3
-
40
-
-
0029766860
-
Pharmacokinetics and pharmacodynamics of subcutaneous interleukin-2 in HIV-infected patients
-
Piscitelli, S.C., Wells, M.J., Metcalf, J.A., Baseler, M., Stevens, R., Davey, R.T. Jr. Pharmacokinetics and pharmacodynamics of subcutaneous interleukin-2 in HIV-infected patients. Pharmacotherapy 1996, 16: 754-9.
-
(1996)
Pharmacotherapy
, vol.16
, pp. 754-759
-
-
Piscitelli, S.C.1
Wells, M.J.2
Metcalf, J.A.3
Baseler, M.4
Stevens, R.5
Davey Jr., R.T.6
-
41
-
-
16944364282
-
Subcutaneous administration of interleukin-2 in human immunodeficiency virus type 1-infected persons
-
Davey, R.T. Jr., Chaitt, D.G., Piscitelli, S.C. et al. Subcutaneous administration of interleukin-2 in human immunodeficiency virus type 1-infected persons. J Infect Dis 1997, 175: 781-9.
-
(1997)
J Infect Dis
, vol.175
, pp. 781-789
-
-
Davey Jr., R.T.1
Chaitt, D.G.2
Piscitelli, S.C.3
-
42
-
-
0001027244
-
A randomized trial of high versus low-dose subcutaneous interleukin-2 outpatient therapy for early human immunodeficiency virus type 1 infection
-
Davey, R.T. Jr., Chaitt, D.G., Albert, J.M. et al. A randomized trial of high versus low-dose subcutaneous interleukin-2 outpatient therapy for early human immunodeficiency virus type 1 infection. J Infect Dis 1999, 179: 849-58.
-
(1999)
J Infect Dis
, vol.179
, pp. 849-858
-
-
Davey Jr., R.T.1
Chaitt, D.G.2
Albert, J.M.3
-
44
-
-
0033738864
-
A randomized, controlled 24-week study of intermittent subcutaneous interleukin-2 in HIV-1 infected patients in Thailand
-
Ruxrungtham, K., Suwanagool, S. Tavel, J.A. et al. A randomized, controlled 24-week study of intermittent subcutaneous interleukin-2 in HIV-1 infected patients in Thailand. AIDS 2000, 14: 2509-13.
-
(2000)
AIDS
, vol.14
, pp. 2509-2513
-
-
Ruxrungtham, K.1
Suwanagool, S.2
Tavel, J.A.3
-
45
-
-
0004781509
-
Immunologic and virologic effects of subcutaneous interleukin 2 in combination with antiretroviral therapy: A randomized controlled trial
-
Davey, R.T. Jr., Murphy, R.L., Graziano, P.M. et al. Immunologic and virologic effects of subcutaneous interleukin 2 in combination with antiretroviral therapy: A randomized controlled trial. JAMA 2000, 284: 183-9.
-
(2000)
JAMA
, vol.284
, pp. 183-189
-
-
Davey Jr., R.T.1
Murphy, R.L.2
Graziano, P.M.3
-
46
-
-
0023038312
-
A phase I/II trial of recombinant interleukin-2 in AIDS/ARC: Alterations of phenotypes of peripheral blood mononuclear cells
-
Flad, H.D., Ernst, M., Kern, P. A phase I/II trial of recombinant interleukin-2 in AIDS/ARC: Alterations of phenotypes of peripheral blood mononuclear cells. Lymphokine Res 1986, 5 (Suppl. 1): S171-6.
-
(1986)
Lymphokine Res
, vol.5
, Issue.SUPPL. 1
-
-
Flad, H.D.1
Ernst, M.2
Kern, P.3
-
47
-
-
0021999943
-
Preliminary clinical observations with recombinant interleukin-2 in patients with AIDS or LAS
-
Kern, P., Toy, J., Dietrich, M. Preliminary clinical observations with recombinant interleukin-2 in patients with AIDS or LAS. Blut 1985, 50: 1-6.
-
(1985)
Blut
, vol.50
, pp. 1-6
-
-
Kern, P.1
Toy, J.2
Dietrich, M.3
-
48
-
-
0023575616
-
Therapy of acquired immune deficiency syndrome with recombinant interleukin-2
-
Volberding, P., Moody, D.J., Beardslee, D., Bradley, E.C., Wofsy, C.B. Therapy of acquired immune deficiency syndrome with recombinant interleukin-2. AIDS Res Human Retroviruses 1987, 3: 115-24.
-
(1987)
AIDS Res Human Retroviruses
, vol.3
, pp. 115-124
-
-
Volberding, P.1
Moody, D.J.2
Beardslee, D.3
Bradley, E.C.4
Wofsy, C.B.5
-
49
-
-
13144252233
-
Regulatory dysfunction of the interleukin-2 receptor during HIV infection and the impact of triple combination therapy
-
David, D., Bani, L., Moreau, J.L. et al. Regulatory dysfunction of the interleukin-2 receptor during HIV infection and the impact of triple combination therapy. Proc Nat Acad Sci USA 1998, 95: 11348-53.
-
(1998)
Proc Nat Acad Sci USA
, vol.95
, pp. 11348-11353
-
-
David, D.1
Bani, L.2
Moreau, J.L.3
-
50
-
-
7844229880
-
Randomized, controlled phase II trial of subcutaneous interleukin-2 in combination with highly active antiretroviral therapy (HAART) in HIV patients
-
Hengge, U.R., Goos, M., Esser, S. et al. Randomized, controlled phase II trial of subcutaneous interleukin-2 in combination with highly active antiretroviral therapy (HAART) in HIV patients. AIDS 1998, 12: F225-34.
-
(1998)
AIDS
, vol.12
-
-
Hengge, U.R.1
Goos, M.2
Esser, S.3
-
51
-
-
0035873085
-
Efficacy of low-dose intermittent subcutaneous interleukin (IL)-2 in antiviral drug-experienced human immunodeficiency virus-infected persons with detectable virus load: A controlled study of 3 IL-2 regimens with antiviral drug therapy
-
Tambussi, G., Ghezzi, S., Nozza, S. et al. Efficacy of low-dose intermittent subcutaneous interleukin (IL)-2 in antiviral drug-experienced human immunodeficiency virus-infected persons with detectable virus load: A controlled study of 3 IL-2 regimens with antiviral drug therapy. J Infect Dis 2001, 183: 1476-84.
-
(2001)
J Infect Dis
, vol.183
, pp. 1476-1484
-
-
Tambussi, G.1
Ghezzi, S.2
Nozza, S.3
-
52
-
-
0037178320
-
Effects of interleukin-2 plus highly active antiretroviral therapy on HIV-1 replication and proviral DNA (COSMIC trial)
-
Stellbrink, H.J., van Lunzen, J., Westby, M. et al. Effects of interleukin-2 plus highly active antiretroviral therapy on HIV-1 replication and proviral DNA (COSMIC trial). AIDS 2002, 16: 1479-87.
-
(2002)
AIDS
, vol.16
, pp. 1479-1487
-
-
Stellbrink, H.J.1
van Lunzen, J.2
Westby, M.3
-
54
-
-
0037436193
-
ANRS 079 Study Group. Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: A randomized controlled trial
-
Levy, Y., Durier, C., Krzysiek, R. et al. ANRS 079 Study Group. Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: A randomized controlled trial. AIDS 2003, 17: 343-51.
-
(2003)
AIDS
, vol.17
, pp. 343-351
-
-
Levy, Y.1
Durier, C.2
Krzysiek, R.3
-
55
-
-
0642347180
-
Terry Beirn Community Program for Clinical Research on AIDS. Nadir CD4+ T cell count predicts response to subcutaneous recombinant interleukin-2
-
Markowitz, N., Bebchuk, J.D., Abrams, D.I.; Terry Beirn Community Program for Clinical Research on AIDS. Nadir CD4+ T cell count predicts response to subcutaneous recombinant interleukin-2. Clin Infect Dis 2003, 37: e115-20.
-
(2003)
Clin Infect Dis
, vol.37
-
-
Markowitz, N.1
Bebchuk, J.D.2
Abrams, D.I.3
-
56
-
-
0035282639
-
Rapid effect of interleukin-2 therapy in human immunodeficiency virus-infected patients whose CD4 cell counts increase only slightly in response to combined antiretroviral treatment
-
David, D., Nait-Ighil, L., Dupont, B., Mara, J., Gachot, B., Theze, J. Rapid effect of interleukin-2 therapy in human immunodeficiency virus-infected patients whose CD4 cell counts increase only slightly in response to combined antiretroviral treatment. J Infect Dis 2001, 183: 730-5.
-
(2001)
J Infect Dis
, vol.183
, pp. 730-735
-
-
David, D.1
Nait-Ighil, L.2
Dupont, B.3
Mara, J.4
Gachot, B.5
Theze, J.6
-
57
-
-
0033017140
-
Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons
-
Arno, A., Ruiz, L., Juan, M. et al. Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons. J Infect Dis 1999, 180: 56-60.
-
(1999)
J Infect Dis
, vol.180
, pp. 56-60
-
-
Arno, A.1
Ruiz, L.2
Juan, M.3
-
58
-
-
0034331263
-
Low-dose daily subcutaneous interleukin-2 in combination with highly active antiretroviral therapy in HIV+ patients: A randomized controlled trial
-
Lalezari, J.P., Beal, J.A., Ruane, P.J. et al. Low-dose daily subcutaneous interleukin-2 in combination with highly active antiretroviral therapy in HIV+ patients: A randomized controlled trial. HIV Clin Trials 2000, 1: 1-15.
-
(2000)
HIV Clin Trials
, vol.1
, pp. 1-15
-
-
Lalezari, J.P.1
Beal, J.A.2
Ruane, P.J.3
-
59
-
-
84878721588
-
-
3: ACTG 328 - Final results at 84 weeks. 8th Conf Retrovir Oppor Infect, Chicago 2001, Abst. 17.
-
3: ACTG 328 - Final results at 84 weeks. 8th Conf Retrovir Oppor Infect, Chicago 2001, Abst. 17.
-
-
-
-
60
-
-
0037131199
-
Interleukin-2 accelerates CD4 cell reconstitution in HIV-infected patients with severe immunosuppression despite highly active antiretroviral therapy: The ILSTIM study - ANRS 082
-
Katlama, C., Carcelain, G., Duvivier, C. et al. Interleukin-2 accelerates CD4 cell reconstitution in HIV-infected patients with severe immunosuppression despite highly active antiretroviral therapy: The ILSTIM study - ANRS 082. AIDS 2002, 16: 2027-34.
-
(2002)
AIDS
, vol.16
, pp. 2027-2034
-
-
Katlama, C.1
Carcelain, G.2
Duvivier, C.3
-
61
-
-
0036720644
-
Low-dose prolonged intermittent interleukin-2 adjuvant therapy: Results of a randomized trial among human immunodeficiency virus-positive patients with advanced immune impairment
-
Marchetti, G., Meroni, L., Varchetta, S. et al. Low-dose prolonged intermittent interleukin-2 adjuvant therapy: Results of a randomized trial among human immunodeficiency virus-positive patients with advanced immune impairment. J Infect Dis 2002, 186: 606-16.
-
(2002)
J Infect Dis
, vol.186
, pp. 606-616
-
-
Marchetti, G.1
Meroni, L.2
Varchetta, S.3
-
62
-
-
84878731048
-
-
Routy, J.P.; for the International SILCAAT Team. Demographics and visit compliance in SILCAAT, a large international phase III clinical endpoint trial with IL-2 as an immune-based therapy adjunctive to ART. XIV Int Conf AIDS, Barcelona 2002, Abst. WePeB5982.
-
Routy, J.P.; for the International SILCAAT Team. Demographics and visit compliance in SILCAAT, a large international phase III clinical endpoint trial with IL-2 as an immune-based therapy adjunctive to ART. XIV Int Conf AIDS, Barcelona 2002, Abst. WePeB5982.
-
-
-
-
63
-
-
0036209488
-
The evaluation of subcutaneous proleukin (interleukin-2) in a randomized international trial: Rationale, design, and methods of ESPRIT
-
Emery, S., Abrams, D.I., Cooper, D.A. et al. The evaluation of subcutaneous proleukin (interleukin-2) in a randomized international trial: Rationale, design, and methods of ESPRIT. Control Clin Trials 2002, 23: 198-220.
-
(2002)
Control Clin Trials
, vol.23
, pp. 198-220
-
-
Emery, S.1
Abrams, D.I.2
Cooper, D.A.3
-
64
-
-
33846944430
-
A randomized trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-Infected patients: The UK-Vanguard Study
-
DOI: 10.1371
-
Youle, M., Emery, S., Fisher, M. et al. A randomized trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-Infected patients: The UK-Vanguard Study. PLoS Clin Trials 2006, 1: e3 DOI: 10.1371.
-
(2006)
PLoS Clin Trials
, vol.1
-
-
Youle, M.1
Emery, S.2
Fisher, M.3
-
65
-
-
0026515571
-
Interleukin-2 by inhalation: Local therapy for metastatic renal cell carcinoma
-
Huland, E., Huland, H., Heinzer, H. Interleukin-2 by inhalation: Local therapy for metastatic renal cell carcinoma. J Urol 1992, 147: 344-8.
-
(1992)
J Urol
, vol.147
, pp. 344-348
-
-
Huland, E.1
Huland, H.2
Heinzer, H.3
-
66
-
-
0031415256
-
Inhaled interleukin-2 therapy in pulmonary metastatic renal cell carcinoma: Six years of experience
-
Huland, E., Heinzer, H., Mir, T.S., Huland, H. Inhaled interleukin-2 therapy in pulmonary metastatic renal cell carcinoma: Six years of experience. Cancer J Sci Am 1997, 3 (Suppl. 1): S98-105.
-
(1997)
Cancer J Sci Am
, vol.3
, Issue.SUPPL. 1
-
-
Huland, E.1
Heinzer, H.2
Mir, T.S.3
Huland, H.4
-
67
-
-
0034355109
-
A comparison of systemic versus inhaled recombinant IL-2 administration for the treatment of metastatic renal cell carcinoma
-
Huland, E., Heinzer, H., Huland, H. A comparison of systemic versus inhaled recombinant IL-2 administration for the treatment of metastatic renal cell carcinoma. Folia Biol (Krakow) 2000, 46: 241-50.
-
(2000)
Folia Biol (Krakow)
, vol.46
, pp. 241-250
-
-
Huland, E.1
Heinzer, H.2
Huland, H.3
-
68
-
-
10744222612
-
Efficacy and safety of inhaled recombinant interleukin-2 in high-risk renal cell cancer patients compared with systemic interleukin-2: An outcome study
-
Huland, E., Burger, A., Fleischer, J. et al. Efficacy and safety of inhaled recombinant interleukin-2 in high-risk renal cell cancer patients compared with systemic interleukin-2: An outcome study. Folia Biol 2003, 49: 183-95.
-
(2003)
Folia Biol
, vol.49
, pp. 183-195
-
-
Huland, E.1
Burger, A.2
Fleischer, J.3
-
69
-
-
0033840128
-
Overview of interleukin-2 inhalation therapy
-
Huland, E., Heinzer, H., Huland, H., Yung, R. Overview of interleukin-2 inhalation therapy. Cancer J Sci Am 2000, 6 (Suppl. 1): S104-12.
-
(2000)
Cancer J Sci Am
, vol.6
, Issue.SUPPL. 1
-
-
Huland, E.1
Heinzer, H.2
Huland, H.3
Yung, R.4
-
70
-
-
0033795671
-
Inhalational interleukin-2 liposomes for pulmonary metastases: A phase I clinical trial
-
Skubitz, K.M., Anderson, P.M. Inhalational interleukin-2 liposomes for pulmonary metastases: A phase I clinical trial. Anticancer Drugs 2000, 11: 555-63.
-
(2000)
Anticancer Drugs
, vol.11
, pp. 555-563
-
-
Skubitz, K.M.1
Anderson, P.M.2
|