Proteomic discovery of 21 proteins expressed in human plasma-derived but not platelet-derived microparticles

Thrombosis and Haemostasis

Volumn 97, Issue 1, 2007, Pages 67-80

  Smalley, David M ^a,b   Root, Karen E ^a,b   Cho, HyungJun ^a,d   Ross, Mark M ^a,b   Ley, Klaus ^b,c  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c University of Virginia School of Medicine   (United States)

^d Korea University   (South Korea)

Author keywords

Platelet activation markers; Secretion exocytosis; Vascular cell markers

Indexed keywords

ACTIN; ALBUMIN; ALPHA 2 MACROGLOBULIN; ALPHA2 INTEGRIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN B100; APOLIPOPROTEIN C3; APOLIPOPROTEIN E3; BLOOD CLOTTING FACTOR 8; CD5 ANTIGEN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4A; COMPLEMENT COMPONENT C4B; GALECTIN 3; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HAPTOGLOBIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; PLECKSTRIN; PROFILIN; PROTEIN S; PROTEIN SH3; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RAS PROTEIN; TENASCIN; TRANSFERRIN; TRANSFERRIN RECEPTOR; VON WILLEBRAND FACTOR;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; EXOCYTOSIS; HUMAN; HUMAN CELL; ISOTOPE LABELING; MICROPARTICLE ENZYME IMMUNOASSAY; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; QUANTITATIVE ANALYSIS; SPECTROSCOPY; THROMBOCYTE;

APOPTOSIS; BLOOD COAGULATION; BLOOD PLATELETS; CELL MEMBRANE; HUMANS; IMMUNITY; IRON; PARTICLE SIZE; PLASMA; PROTEINS; PROTEOMICS;

EID: 33846951816     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH06-02-0066     Document Type: Article

References (58)

1. Hugel B, Martinez MC, Kunzelmann C, et al. Membrane microparticles: two sides of the coin. Physiology 2005; 20: 22-7.
2. Pilzer D, Gasser O, Moskovich O, et al. Emission of membrane vesicles: roles in complement resistance, immunity and cancer. Semin Immunopathol 2005; 1-13.
3. Wolf P. The nature and significance of platelet products in human plasma. Br J Haematol 1967; 13: 269-88.
4. Horstman LL, Ahn YS. Platelet microparticles: a wide-angle perspective. Crit Rev Oncol Hematol 1999; 30: 111-42.
5. VanWijk MJ, VanBavel E, Sturk A, et al. Microparticles in cardiovascular diseases. Cardiovasc Res 2003; 59: 277-87.
6. Mallat Z, Hugel B, Ohan J, et al. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation 1999; 99: 348-53.
7. Gasser O, Hess C, Miot S, et al. Characterisation and properties of ectosomes released by human poly-morphonuclear neutrophils. Exp Cell Res 2003; 285: 243-57.
8. Jimenez JJ, Jy W, Mauro L., et al. Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis. Thromb Res 2003; 109: 175-80.
9. Watanabe J, Marathe G K, Neilsen PO, et al. Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles. J Biol Chem 2003; 278: 33161-8.
10. MacKenzie A, Wilson HL, Kiss-Toth E, et al. Rapid secretion of interleukin-1beta by microvesicle shedding. Immunity 2001; 15: 825-35.
11. Morel O, Toti F, Hugel B, et al. Cellular microparticles: a disseminated storage pool of bioactive vascular effectors. Curr Opin Hematol 2004; 11: 156-64.
12. Barry OP, Pratico D, Savani RC, et al. Modulation of monocyte-endothelial cell interactions by platelet microparticles. J Clin Invest 1998; 102: 136-44.
13. Mesri M, Altieri DC. Leukocyte microparticles stimulate endothelial cell cytokine release and tissue factor induction in a JNK1 signaling pathway. J Biol Chem 1999; 274: 23111-8.
14. Distler JH, Jungel A, Huber LC, et al. The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. Proc Natl Acad Sci USA 2005; 102: 2892-7.
15. Pfister SL. Role of platelet microparticles in the production of thromboxane by rabbit pulmonary artery. Hypertension 2004; 43: 428-33.
16. Brill A, Dashevsky O, Rivo J, et al. Platelet-derived microparticles induce angiogenesis and stimulate postischemic revascularization. Cardiovasc Res 2005; 67: 30-8.
17. Gasser O, Schifferli JA. Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis. Blood 2004; 104: 2543-8.
18. Falati S, Liu Q, Gross P, et al. Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin. J Exp Med 2003; 197: 1585-98.
19. Hrachovinova I, Cambien B, Hafezi-Moghadam A, et al. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nat Med 2003; 9: 1020-5.
20. Garcia BA, Smalley DM, Cho H, et al. The Platelet Microparticle Proteome. J Proteome Res 2005; 4: 1516-21.
21. Shevchenko A, Wilm M, Vorm O, et al. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 1996; 68: 850-8.
22. Washburn MP, Wolters D, Yates JR 3rd. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol 2001; 19: 242-7.
23. Palagi PM, Walther D, Quadroni M, et al. MSight: an image analysis software for liquid chromatography-mass spectrometry. Proteomics 2005; 5: 2381-4.
24. Martinez MC, Tesse A, Zobairi F, et al. Shed membrane microparticles from circulating and vascular cells in regulating vascular function. Am J Physiol Heart Circ Physiol 2005; 288: H1004-1009.
25. Forlow SB, McEver RP, Nollert MU. Leukocyte-leukocyte interactions mediated by platelet microparticles under flow. Blood 2000; 95: 1317-23.
26. Thery C, Zitvogel L, Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol 2002; 2: 569-79.
27. Shet AS, Aras O, Gupta K, et al. Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Blood 2003; 102: 2678-83.
28. Jin M, Drwal G, Bourgeois T, et al. Distinct proteome features of plasma microparticles. Proteomics 2005; 5: 1940-52.
29. Zellner M, Winkler W, Hayden H, et al. Quantitative validation of different protein precipitation methods in proteome analysis of blood platelets. Electrophoresis 2005; 26: 2481-9.
30. Johnstone RM. Revisiting the road to the discovery of exosomes. Blood Cells Mol Dis 2005; 34: 214-9.
31. Fishelson Z, Attali G, Mevorach D. Complement and apoptosis. Mol Immunol 2001; 38: 207-19.
32. Morgan BP. Regulation of the complement membrane attack pathway. Crit Rev Immunol 1999; 19: 173-98.
33. Dighiero G, Rose NR. Critical self-epitopes are key to the understanding of self-tolerance and autoimmunity. Immunol Today 1999; 20: 423-8.
34. Binder CJ, Horkko S, Dewan A, et al. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med 2003; 9: 736-43.
35. Blom AM, Villoutreix BO, Dahlback B. Complement inhibitor C4b-binding protein-friend or foe in the innate immune system? Mol Immunol 2004; 40: 1333-46.
36. Anderson HA, Maylock CA, Williams JA, et al. Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells. Nat Immunol 2003; 4: 87-91.
37. Joseph SB, Bradley MN, Castrillo A, et al. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell 2004; 119: 299-309.
38. Miyazaki T, Hirokami Y, Matsuhashi N, et al. Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily. J Exp Med 1999; 189: 413-22.
39. Krzeslak A, Lipinska A. Galectin-3 as a multifunctional protein. Cell Mol Biol Lett 2004; 9: 305-28.
40. Akahani S, Nangia-Makker P, Inohara H, et al. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res 1997; 57: 5272-6.
41. Aisen P. Transferrin receptor 1. Int J Biochem Cell Biol 2004; 36: 2137-43.
42. Pan BT, Teng K, Wu C, et al. Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes. J Cell Biol 1985; 101: 942-8.
43. Harding C, Heuser J, Stahl P. Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. J Cell Biol 1983; 97: 329-39.
44. Madsen M, Graversen JH, Moestrup SK. Haptoglobin and CD163: captor and receptor gating hemoglobin to macrophage lysosomes. Redox Rep 2001; 6: 386-8.
45. Lim SK, Kim H, Lim SK, et al. Increased susceptibility in Hp knockout mice during acute hemolysis. Blood 1998; 92: 1870-7.
46. Koppelman SJ, Hackeng TM, Sixma JJ, et al. Inhibition of the intrinsic factor X activating complex by protein S: evidence for a specific binding of protein S to factor VIII. Blood 1995; 86: 1062-71.
47. Padilla A, Moake JL, Bernardo A, et al. P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface. Blood 2004; 103: 2150-6.
48. Kroll MH, Harris TS, Moake JL, et al. von Willebrand factor binding to platelet GpIb initiates signals for platelet activation. J Clin Invest 1991; 88: 1568-73.
49. Goto S, Ikeda Y, Saldivar E, et al. Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions. J Clin Invest 1998; 101: 479-86.
50. Reininger AJ, Heijnen HF, Schumann H, et al. Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress. Blood 2006;
51. Jimenez JJ, Jy W, Mauro LM, Horstman LL et al. Endothelial microparticles released in thrombotic thrombocytopenic purpura express von Willebrand factor and markers of endothelial activation. Br J Haematol 2003; 123: 896-902.
52. Lopez JA, Dong JF. Cleavage of von Willebrand factor by ADAMTS-13 on endothelial cells. Semin Hematol 2004; 41: 15-23.
53. Rubin DC, Swietlicki EA, Iordanov H, et al. Novel goblet cell gene related to IgGFcγBP is regulated in adapting gut after small bowel resection. Am J Physiol Gastrointest Liver Physiol 2000; 279: G1003-1010.
54. Harada N, Iijima S, Kobayashi K, et al. Human IgGFc binding protein (FcγBP) in colonic epithelial cells exhibits mucin-like structure. J Biol Chem 1997; 272: 15232-41.
55. Kobayashi K, Ogata H, Morikawa M, et al. Distribution and partial characterisation of IgG Fc binding protein in various mucin producing cells and body fluids. Gut 2002; 51: 169-76.
56. Hsia HC, Schwarzbauer JE. Meet the tenascins: multifunctional and mysterious. J Biol Chem 2005; 280: 26641-4.
57. Schecter AD, Spirn B, Rossikhina M, et al. Release of active tissue factor by human arterial smooth muscle cells. Circ Res 2000; 87: 126-32.
58. Martin DM, Boys CW, Ruf W. Tissue factor: molecular recognition and cofactor function. Faseb J 1995; 9: 852-9.