Low hematocrit worsens cerebral injury after prolonged hypothermic circulatory arrest in rats

Canadian Journal of Anesthesia

Volumn 53, Issue 12, 2006, Pages 1220-1229

  Su, Dian San ^a   Wang, Xiang Rui ^a   Zheng, Yongjun ^a   Zhao, Yan Hua ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAL HYDRATE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CARDIOPULMONARY BYPASS; CELL DAMAGE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HEART ARREST; HEMATOCRIT; HEMODILUTION; HIPPOCAMPUS; HYPOTHERMIA; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRION; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PARIETAL LOBE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

EID: 33846948746     PISSN: 0832610X     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03021584     Document Type: Article

References (40)

1. Neptune WB, Bougas JA, Panico FG. Open-heart surgery without the need for donor-blood priming in the pump oxygenator. N Engl J Med 1960; 263: 111-5.
2. Gadboys HL, Slonim R, Litwak RS. Homologous blood syndrome: I. Preliminary observations on its relationship to cardiopulmonary bypass. Ann Surg 1962; 156: 793-804.
3. Nollert G, Sperling J, Sakamoto T, Jaeger BR, Jonas RA. Higher hematocrit improves liver blood flow and metabolism during cardiopulmonary bypass in piglets. Thorac Cardiovasc Surg 2001; 49: 226-30.
4. Cooper JR Jr. Perioperative considerations in Jehovah's Witnesses. Int Anesthesiol Clin 1990; 28: 210-5.
5. Hammon JW, Stump DA, Butterwortb JB, Moody DM. Approaches to reduce neurologic complications during cardiac surgery. Semin Thorac Cardiovasc Surg 2001; 13: 184-91.
6. Duebener LF, Sakamoto T, Hatsuoka S, et al. Effects of hematocrit on cerebral microcirculation and tissue oxygenation during deep hypothermic bypass. Circulation 2001; 104(12 Suppl 1): I-260-4.
7. Shin'oka T, Shum-Tim D, Jonas RA, et al. Higher hematocrit improves cerebral outcome after deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg 1996; 112: 1610-20.
8. Shin'oka T, Shum-Tim D, Laussen PC, et al. Effects of oncotic pressure and hernatocrit on outcome after hypothermia circulatory arrest. Ann Thorac Surg 1998; 65: 155-64.
9. Jonas RA, Wypij D, Roth SJ, et al. The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants. J Thorac Cardiovasc Surg 2003; 126: 1765-74.
10. Habib RH, Zacharias A, Schwann TA, Riordan CJ, Durbam SJ, Shah A. Adverse effects of low hematocrit during cardiopulmonary bypass in the adult: should current practice be changed? J Thorac Cardiovasc Surg 2003; 125: 1438-50.
11. Su DS, Wang XR, Zbeng YJ, Zbao YH, Zhang TJ. Retrograde cerebral perfusion of oxygenated, compacted red blood cells attenuates brain damage after hypothermia circulation arrest of rat. Acta Anaesthesiol Scand 2005; 49: 1172-81.
12. Choi DW. Ischemia-induced neuronal apoptosis. Curr Opin Neurobiol 1996; 6: 667-72.
13. MacManus JP, Linnik MD. Gene expression induced by cerebral ischemia: an apoptotic perspective. J Cereb Blood Flow Metab 1997; 17: 815-32.
14. Chopp M, Li Y. Apoptosis in focal cerebral ischemia. Acta Neurochir Suppl 1996; 66: 21-6.
15. Safar P, Stezoski W, Nemoto EM. Amelioration of brain damage after 12 minutes' cardiac arrest in dogs. Arch Neurol 1976; 33: 91-5.
16. Niazi SA, Lewis FJ. Profound hypothermia. Report of a case. Ann Surg 1958; 147: 264-6.
17. Coselli JS, Buket S, Djukanovic B. Aortic arch operation: current treatment and results. Ann Thorac Surg 1995; 59: 19-27.
18. Koucboukos NT, Daily BB, Rokkas CK, Murpby SF, Bauer S, Abboud N. Hypothermic bypass and circulatory arrest for operations on the descending thoracic and thoracoabdominal aorta. Ann Thorac Surg 1995; 60: 67-77.
19. Kirklin TW, Barratt-Boyes BG. Hypothermia circulatory arrest and cardiopulmonary bypass. In: Krklin JW, Barratt- Boyes BG (Eds). Cardiac Surgery, 3rd ed. New York: Churchill Livingstone Inc., 2003: 66-130.
20. Newburger TW, Jonas RA, Wernovsky G, et al. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. N Engl J Med 1993; 329: 1057-64.
21. Bellinger DC, Jonas RA, Rappaport LA, et al. Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. N Engl J Med 1995; 332: 549-55.
22. Davis EA, Gillinov AM, Cameron DE, Reitz BA. Hypothermic circulatory arrest as a surgical adjunct: a 5-year experience with 60 adult patients. Ann Thorac Surg 1992; 53: 402-7.
23. Chaudhary G, Sinha K, Gupta YK. Protective effect of exogenous administration of alpha-tocopherol in middle cerebral artery occlusion model of cerebral ischemia in rats. Fundam Clin Pharmacol 2003; 17: 703-7.
24. Salman AE, Dal D, Salman MA, Iskit AB, Aypar U. The effect of ketamine on acute muscular ischaemia reperfusion in rats. Eur J Anaesthesiol 2005; 22: 712-6.
25. Hare GM, Mazer CD, Mak W, et al. Hemodilutional anemia is associated with increased cerebral neuronal nitric oxide synthase gene expression. J Appl Physiol 2003; 94: 2058-67.
26. Sakamoto T, Zurakowski D, Duebener LF, et al. Combination of alpha-stat strategy and hemodilution exacerbates neurologic injury in a survival piglet model with deep hypothermic circulatory arrest. Ann Thorac Surg 2002; 73: 180-9.
27. Reasoner DK, Ryu KH, Hindman BJ, Cutkomp J, Smith T. Marked hemodilution increases neurologic injury after focal cerebral ischernia in rabbits. Anesth Analg 1996; 82: 61-7.
28. Groom RC. High or low hematocrits during cardiopulmonary bypass for patients undergoing coronary artery bypass graft surgery? An evidence-based approach to the question. Perfusion 2001; 16: 339-43.
29. MacManus JP, Linnik MD. Gene expression induced by cerebral ischemia: an apoptotic perspective. J Cereb Blood Flow Metab 1997; 17: 815-32.
30. Newman M, Kirchner J, Phillips-Bute B, et al. Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery. N Engl J Med 2001; 344: 395-402.
31. Kurth CD, Priestley M, Golden J, McCann J, Raghupathi R. Regional patterns of neuronal death after deep hypothermic circulatory arrest in newborn pigs. J Thorac Cardiovasc Surg 1999; 118: 1068-77.
32. Kin H, Ishibasbi K, Nitatori T, Kawazoe K. Hippocampal neuronal death following deep hypothermic circulatory arrest in dogs: involvement of apoptosis. Cardiovasc Surg 1999, 7: 558-64.
33. Krajewska M, Rosenthal RE, Mikolajczyk J, et al. Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation. Exp Neurol 2004; 189: 261-79.
34. Sato Y, Laskowitz DT, Bennett ER, Newman MF, Warner DS, Grocott HP. Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis? Anesth Anaig 2002; 94: 1389-94.
35. Yeh CH, Wang YC, Wu YC, Lin YM, Lin PJ. Ischemic preconditioning or heat shock pretreatment ameliorates neuronal apoptosis following hypothermic circulatory arrest. J Thorac Cardiovasc Surg 2004; 128: 203-10.
36. Bokesch PM, Marcband J, Seiraft P, et al. Immediate-early gene expression in ovine brain after cardiopulmonary bypass and hypothermic circulatory arrest. Anesthesiology 1996; 85: 1439-46.
37. Eldadah BA, Faden AI. Caspase pathways, neuronal apoptosis, and CNS injury. J Neurotrauma 2000; 17: 811-29.
38. Siesjo BK. Acidosis and ischernic brain damage. Neurochem Pathol 1988; 9: 31-88.
39. Kawaguchi AT, Yamano M, Naritomi H, Ishibashi-Ueda H, Yamatodani A, Koide S. Neurological function after deep hypothermic circulatory arrest in the rat. Circulation 1998; 98(19 Suppl): 11385-9.
40. Svensson LG, Crawford ES, Hess KR, et al. Deep hypothermia with circulatory arrest. Determinants of stroke and early mortality in 656 patients. J Thorac Cardiuovasc Surg 1993; 106: 19-31.