Differential cerebral gene expression during cardiopulmonary bypass in the rat: Evidence for apoptosis?

Anesthesia and Analgesia

Volumn 94, Issue 6, 2002, Pages 1389-1394

  Sato, Yukie ^a   Laskowitz, Daniel T ^a   Bennett, Ellen R ^a   Newman, Mark F ^a   Warner, David S ^a   Grocott, Hilary P ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 2; CASPASE 3; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN HOMOGENATE; BRAIN INJURY; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; MALE; MOLECULAR BIOLOGY; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA ANALYSIS;

EID: 0036258643     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-200206000-00003     Document Type: Article

References (36)

1. Neuro-psychological changes after cardiac surgery: A critical review
2. Adverse neurologic events: Risks of intracardiac versus extracardiac surgery
3. Adverse cerebral outcomes after coronary bypass surgery
4. Cerebral injury after cardiac surgery: Identification of a group at extraordinary risk - Multicenter Study of Perioperative Ischemia Research Group (McSPI) and the Ischemia Research Education Foundation (IREF) investigators
5. Neuropsychiatric complications after cardiopulmonary bypass: Cerebral protection by a barbiturate
6. Brain damage and neurological outcome after open-heart surgery
7. Longitudinal assessment of neurocognitive function after coronary bypass surgery
8. The impact of microemboli during cardiopulmonary bypass on neuropsychological functioning
9. Cerebral emboli and cognitive outcome after cardiac surgery
10. Cerebral hypoxia during cardiopulmonary bypass: A magnetic resonance imaging study
11. Cardiopulmonary bypass and the inflammatory response: A role for serine protease inhibitors?
12. Continuous jugular venous versus nasopharyngeal temperature monitoring during hypothermic cardiopulmonary bypass for cardiac surgery
13. Cerebral hyperthermia during cardiopulmonary bypass in adults
14. Randomized trial of normothermic versus hypothermic coronary bypass surgery: The warm heart investigators
15. The effect of temperature management during cardiopulmonary bypass on neurologic and neuropsychologic outcomes in patients undergoing coronary revascularizatlon
16. Preliminary report of a genetic basis for cognitive decline after cardiac operations
17. Immediate-early gene expression in ovine brain after cardiopulmonary bypass and hypothermic circulatory arrest
18. Brain expression of inducible cyclooxygenase 2 messenger RNA in rats undergoing cardiopulmonary bypass
19. Ischemia-induced neuronal apoptosis
20. Gene expression induced by cerebral ischemia: An apoptotic perspective
21. Apoptosis in focal cerebral ischemia
22. Neurological injury during cardiopulmonary bypass in the rat
23. Cardiopulmonary bypass induces neurologic and neurocognitive dysfunction in the rat
24. Extracellular pH, potassium, and calcium activities in progressive ischaemia of rat cortex
25. The effect of magnesium on neurologic outcome following cardiopulmonary bypass in the rat
26. The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes
27. Damage, repair, and mutagenesis in nuclear genes after mouse forebrain ischemia-reperfusion
28. Caspase pathways, neuronal apoptosis, and CNS injury
29. Acidosis and ischemic brain damage
30. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
31. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
32. Activation of caspase-3 in developmental models of programmed cell death in neurons of the substantia nigra
33. Caspase-3 mediated neuronal death after traumatic brain injury in rats
34. Two distinct pathways leading to nuclear apoptosis
35. Regional patterns of neuronal death after deep hypothermic circulatory arrest in newborn pigs