Microparticle adhesive dynamics and rolling mediated by selectin-specific antibodies under flow

Biotechnology and Bioengineering

Volumn 96, Issue 3, 2007, Pages 596-607

  Ham, Anthony Sang Won ^a   Goetz, Douglas J ^b   Klibanov, Alexander L ^c   Lawrence, Michael B ^a  

^a University of Virginia   (United States)

^b Ohio University   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Drug targeting; E selectin; HuEP; Microparticles; P selectin; Rolling

Indexed keywords

DRUG TARGETING; E-SELECTIN; FLOW CHAMBER; FLOW RATES; HUEP; IN VITRO STUDIES; MICROPARTICLES; P-SELECTIN;

ADHESIVES; CARBOHYDRATES; GENETIC ENGINEERING; POLYSTYRENES; ROLLING;

ANTIBODIES;

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY BBIG E4; MONOCLONAL ANTIBODY G1; MONOCLONAL ANTIBODY HAE 1F; MONOCLONAL ANTIBODY HUEP5C7.G2; MONOCLONAL ANTIBODY WAPS12.2; P SELECTIN GLYCOPROTEIN LIGAND 1; PADGEM PROTEIN; POLYSTYRENE; SIALYL LEWIS X ANTIGEN; UNCLASSIFIED DRUG;

ANTIBODY SPECIFICITY; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONTROLLED STUDY; FLOW; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR INTERACTION; MOLECULAR STABILITY; PARTICLE SIZE; PARTICULATE MATTER; PROTEIN BINDING; PROTEIN IMMOBILIZATION; SHEAR RATE;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD FLOW VELOCITY; CELL ADHESION; E-SELECTIN; HUMANS; INFLAMMATION; LEUKOCYTE ROLLING; LIGANDS; MICE; MICROSPHERES; MODELS, IMMUNOLOGICAL; P-SELECTIN; POLYSTYRENES; SHEAR STRENGTH;

EID: 33846922349     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21153     Document Type: Article

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