Plasma concentration of organochlorine compounds is associated with age and not obesity

Chemosphere

Volumn 67, Issue 7, 2007, Pages 1463-1467

  Hue, Olivier ^a   Marcotte, Julie ^a   Berrigan, Félix ^a   Simoneau, Martin ^a   Doré, Jean ^a   Marceau, Picard ^a,b   Marceau, Simon ^a,b   Tremblay, Angelo ^a   Teasdale, Normand ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Age; BMI; Obesity; Organochlorines; Pesticides

Indexed keywords

CHLORINE COMPOUNDS; CONCENTRATION (PROCESS); DISEASES; REGRESSION ANALYSIS; TOXIC MATERIALS; TOXICITY;

AGE; OBESITY; ORGANOCHLORINES;

PESTICIDES;

ORGANOCHLORINE DERIVATIVE;

CHLORINE COMPOUNDS; CONCENTRATION (PROCESS); DISEASES; PESTICIDES; REGRESSION ANALYSIS; TOXIC MATERIALS; TOXICITY;

AGE-RELATED DIFFERENCE; BODY MASS; FAT RESERVE; HEALTH RISK; HEMATOLOGY; OBESITY; ORGANOCHLORINE; PESTICIDE; PLASMA; RISK ASSESSMENT; TOXIC MATERIAL;

ADULT; AGE; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; CORRELATION ANALYSIS; DILUTION; DISEASE ASSOCIATION; DRUG BLOOD LEVEL; HUMAN; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; OBESITY; PARKINSON DISEASE; STEADY STATE;

EID: 33846911279     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2006.10.033     Document Type: Article

References (18)

1. Charlier C., Desaive C., and Plomteux G. Human exposure to endocrine disrupters: consequences of gastroplasty on plasma concentration of toxic pollutants. Int. J. Obes. Relat. Metab. Disord. 26 (2002) 1465-1468
2. Chevrier J., Dewailly E., Ayotte P., Mauriege P., Despres J.-P., and Tremblay A. Body weight loss increases plasma and adipose tissue concentrations of potentially toxic pollutants in obese individuals. Int. J. Obes. Relat. Metab. Disord. 24 (2000) 1272-1278
3. Corrigan F.M., Murray L., Wyatt C.L., and Shore R.F. Diothosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease. Exp. Neurol. 150 (1998) 339-342
4. Corrigan F.M., Wienburg C.L., Shore R.F., Daniel S.E., and Mann D. Organochlorine insecticides in substantia nigra in Parkinson's disease. J. Toxicol. Environ. Health A 59 (2000) 229-234
5. Dellinger J. Exposure assessment and initial intervention regarding fish consumption to tribal members of the Upper Great Lakes region in the United States. Environ. Res. 95 (2004) 325-340
6. Dewailly E., Mulvad G., Pedersen H.S., Ayotte P., Demers A., Weber J.P., and Hansen J.C. Concentration of organochlorines in human brain, liver, and adipose tissue autopsy samples from Greenland. Environ. Health Perspect. 107 (1999) 823-828
7. Imbeault P., Chevrier J., Dewailly E., Ayotte P., Despres J.-P., Tremblay A., and Mauriege P. Increase in plasma pollutant levels in response to weight loss is related in vitro subcutaneous adipocyte basal lipolysis. Int. J. Obes. Relat. Metab. Disord. 25 (2001) 1585-1591
8. Kamel F., and Hoppin J.A. Association of pesticide exposure with neurologic dysfunction and disease. Environ. Health Perspect. 112 (2004) 950-958
9. Kiviranta H., Tuomisto J.T., Tuomisto J., Tukiainen E., and Vartiainen T. Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in the general population in Finland. Chemosphere 60 (2005) 854-869
10. Kopelman P.G. Obesity as a medical problem. Nature 404 (2000) 635-643
11. Luotamo M., Jarvisalo J., and Aitio A. Assessment of exposure to polychlorinated biphenyls: analysis of selected isomers in blood and adipose tissue. Environ. Res. 54 (1991) 121-134
12. Muhlebach S., Wyss P.A., and Bickel M.H. The use of 2,4,5,2′,4′,5′-hexachlorobiphenyl (6-CB) as an unmetabolizable lipophilic model compound. Pharmacol. Toxicol. 69 (1991) 410-415
13. Must A., Spadano J., Coakley E.H., Field A.E., Colditz G., and Dietz W.H. The disease burden associated with overweight and obesity. J.A.M.A. 282 (1999) 1523-1529
14. Patterson Jr. D.G., Isaacs S.G., Alexander L.R., Turner W.E., Hampton L., Bernert J.T., and Needham L.L. Determination of specific polychlorinated dibenzo-p-dioxins and dibenzofurans in blood and adipose tissue by isotope dilution-high-resolution mass spectrometry. IARC Sci. Publ. 108 (1991) 299-342
15. Pelletier C., Després J.-P., and Tremblay A. Palsma organochlorine concentration in endurance athletes and obese individuals. Med. Sci. Sports Exerc. 4 (2002) 1971-1975
16. Pi-Sunyer F.X. The obesity epidemic: pathophysiology and consequences of obesity. Obes. Res. 10 (2002) 97-104
17. Turci R., Mariani G., Marinaccio A., Balducci C., Bettinelli M., Fanelli R., Nichetti S., and Minoia C. Critical evaluation of a high-throughput analytical method for polychlorinated biphenyls in human serum: which detector for the establishment of the reference values?. Rapid. Commun. Mass Spectrom. 18 (2004) 421-434
18. Voorspoels S., Covaci A., Maervoet J., and Schepens P. Relationship between age and levels of organochlorine contaminants in human serum of a belgian population. Bull. Environ. Contam. Toxicol. 69 (2002) 22-29