Deficits in eye movement control in children with fetal alcohol spectrum disorders

Alcoholism: Clinical and Experimental Research

Volumn 31, Issue 3, 2007, Pages 500-511

  Green, Courtney R ^a   Munoz, Douglas P ^a,b   Nikkel, Sarah M ^c   Reynolds, James N ^a,b  

^a QUEEN S UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

Diagnostic Tool; Executive Function; Eye Movement; FASD; Saccade

Indexed keywords

ARTICLE; CHILD; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EYE MOVEMENT CONTROL; EYE MOVEMENT DISORDER; FEMALE; FETAL ALCOHOL SPECTRUM DISORDER; FETAL ALCOHOL SYNDROME; FRONTAL LOBE; HUMAN; MALE; MOTOR CONTROL; PERIPHERAL VISION; PRIORITY JOURNAL; REACTION TIME; SACCADIC EYE MOVEMENT; VISUAL FIELD;

CHILD; EYE MOVEMENT MEASUREMENTS; FEMALE; FETAL ALCOHOL SYNDROME; HUMANS; MALE; PREGNANCY; SACCADES;

EID: 33846907513     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2006.00335.x     Document Type: Article

References (70)

1. Aman CJ, Roberts RJ Jr., Pennington BF (1998) A neuropsychological examination of the underlying deficit in attention deficit hyperactivity disorder: frontal lobe versus right parietal lobe theories. Dev Psychol 34:956-969.
2. Armstrong IT, Munoz DP (2003) Inhibitory control of eye movements during oculomotor countermanding in adults with attention-deficit hyperactivity disorder. Exp Brain Res 152:444-452.
3. Astley SJ, Clarren SK (2000) Diagnosing the full spectrum of fetal alcohol-exposed individuals: introducing the 4-digit diagnostic code. Alcohol Alcohol 35:400-410.
4. Bailey CD, Brien JF, Reynolds JN (1999) Altered GABA(A)-benzodiazepine receptor number and pharmacology in the adult guinea pig cerebral cortex after chronic prenatal ethanol exposure. Alcohol Clin Exp Res 23:1816-1824.
5. Bailey CD, Brien JF, Reynolds JN (2001) Chronic prenatal ethanol exposure increases GABA(A) receptor subunit protein expression in the adult guinea pig cerebral cortex. J Neurosci 21:4381-4389.
6. Cairney S, Maruff P, Vance A, Barnett R, Luk E, Currie J (2001) Contextual abnormalities of saccadic inhibition in children with attention deficit hyperactivity disorder. Exp Brain Res 141:507-518.
7. Chan F, Armstrong IT, Pari G, Riopelle RJ, Munoz DP (2005) Deficits in saccadic eye-movement control in Parkinson's disease. Neuropsychologia 43:784-796.
8. Chudley AE, Conry J, Cook JL, Loock C, Rosales T, LeBlanc N (2005) Fetal alcohol spectrum disorder: Canadian guidelines for diagnosis. Can Med Assoc J 172:S1-S21.
9. Clarren SK, Smith DW (1978) The fetal alcohol syndrome. N Engl J Med 298:1063-1067.
10. Coles CD, Platzman KA, Raskind-Hood CL, Brown RT, Falek A, Smith IE (1997) A comparison of children affected by prenatal alcohol exposure and attention deficit, hyperactivity disorder. Alcohol Clin Exp Res 21:150-161.
11. Condy C, Wattiez N, Rivaud-Pechoux S, Tremblay L, Gaymard B (2007) Antisaccade deficit after inactivation of the principal sulcus in monkeys. Cereb Cortex 17:221-229.
12. Connor PD, Sampson PD, Bookstein FL, Barr HM, Streissguth AP (2000) Direct and indirect effects of prenatal alcohol damage on executive function. Dev Neuropsychol 18:331-354.
13. Crawford TJ, Henderson L, Kennard C (1989) Abnormalities of non-visually-guided eye movements in Parkinson's disease. Brain 112 (part 6): 1573-1586.
14. Crawford TJ, Higham S, Renvoize T, Patel J, Dale M, Suriya A, Tetley S (2005) Inhibitory control of saccadic eye movements and cognitive impairment in Alzheimer's disease. Biol Psychiatry 57:1052-1060.
15. Currie J, Joyce S, Maruff P, Ramsden B, McArthur-Jackson C, Malone V (1993) Selective impairment of express saccade generation in patients with schizophrenia. Exp Brain Res 97:343-348.
16. Dias EC, Segraves MA (1999) Muscimol-induced inactivation of monkey frontal eye field: effects on visually and memory-guided saccades. J Neurophysiol 81:2191-2214.
17. Dorris MC, Pare M, Munoz DP (1997) Neuronal activity in monkey superior colliculus related to the initiation of saccadic eye movements. J Neurosci 17:8566-8579.
18. Fischer B, Biscaldi M, Gezeck S (1997) On the development of voluntary and reflexive components in human saccade generation. Brain Res 754:285-297.
19. Fischer B, Ramsperger E (1984) Human express saccades: extremely short reaction times of goal directed eye movements. Exp Brain Res 57:191-195.
20. Funahashi S (2001) Neuronal mechanisms of executive control by the prefrontal cortex. Neurosci Res 39:147-165.
21. Gaymard B, Ploner CJ, Rivaud S, Vermersch AI, Pierrot-Deseilligny C (1998) Cortical control of saccades. Exp Brain Res 123:159-163.
22. Green CR, Munoz DP, Reynolds JN (2004) Evaluation of saccadic eye movement as a new diagnostic tool for fetal alcohol syndrome (FAS). Perinatal Investigators 28th Annual Meeting, Kingston, Ontario, Canada.
23. Green CR, Munoz DP, Reynolds JN (2005) Saccadic eye movements: a novel diagnostic approach to fetal alcohol syndrome (FAS). Society for Neuroscience 35th Annual Meeting, Washington, DC.
24. Green CR, Munoz DP, Reynolds JN (2006) Children with fetal alcohol spectrum disorders display a unique pattern of deficits in eye movement behaviours. International Society for Biomedical Research on Alcoholism, Sydney, Australia.
25. Guitton D, Buchtel HA, Douglas RM (1985) Frontal lobe lesions in man cause difficulties in suppressing reflexive glances and in generating goal-directed saccades. Exp Brain Res 58:455-472.
26. Hallett PE (1978) Primary and secondary saccades to goals defined by instructions. Vision Res 18:1279-1296.
27. Hanisch C, Radach R, Holtkamp K, Herpertz-Dahlmann B, Konrad K (2006) Oculomotor inhibition in children with and without attention-deficit hyperactivity disorder (ADHD). J Neural Transm 113:671-684.
28. Hays AV, Richmond RJ, Optician LM (1982) A UNIX-based multiple process system for real-time data acquisition and control. WESCON 2:1-10.
29. Hikosaka O, Takikawa Y, Kawagoe R (2000) Role of the basal ganglia in the control of purposive saccadic eye movements. Physiol Rev 80:953-978.
30. Katzung BG (1998) Basic & Clinical Pharmacology. Appleton & Lange, Stamford.
31. Kimmig H, Haussmann K, Mergner T, Lucking CH (2002) What is pathological with gaze shift fragmentation in Parkinson's disease? J Neurol 249:683-692.
32. Klein CH, Raschke A, Brandenbusch A (2003) Development of pro- and antisaccades in children with attention-deficit hyperactivity disorder (ADHD) and healthy controls. Psychophysiology 40:17-28.
33. Kopera-Frye K, Dehaene S, Streissguth AP (1996) Impairments of number processing induced by prenatal alcohol exposure. Neuropsychologia 34:1187-1196.
34. Koren G, Nulman I, Chudley AE, Loock C (2003) Fetal alcohol spectrum disorder. Can Med Assoc J 169:1181-1185.
35. Le Heron CJ, MacAskill MR, Anderson TJ (2005) Memory-guided saccades in Parkinson's disease: long delays can improve performance. Exp Brain Res 161:293-298.
36. Leichnetz GR (1981) The prefrontal cortico-oculomotor trajectories in the monkey. J Neurol Sci 49:387-396.
37. Leigh RJ, Kennard C (2004) Using saccades as a research tool in the clinical neurosciences. Brain 127:460-477.
38. Leigh RJ, Zee DS (1999) The Neurology of Eye Movements. Davis, Philadelphia, PA.
39. LeVasseur AL, Flanagan JR, Riopelle RJ, Munoz DP (2001) Control of volitional and reflexive saccades in Tourette's syndrome. Brain 124:2045-2058.
40. Lezak MD (1995) Neuropsychological Assessment, 3rd ed., Oxford University Press Inc., New York.
41. Luce RD (1986) Response Times: Their Role in Inferring Elementary Mental Organization. Oxford Press, Oxford.
42. Mattson SN, Goodman AM, Caine C, Delis DC, Riley EP (1999) Executive functioning in children with heavy prenatal alcohol exposure. Alcohol Clin Exp Res 23:1808-1815.
43. Mattson SN, Schoenfeld AM, Riley EP (2001) Teratogenic effects of alcohol on brain and behavior. Alcohol Res Health 25:185-191.
44. Mostofsky SH, Lasker AG, Cutting LE, Denckla MB, Zee DS (2001) Oculomotor abnormalities in attention deficit hyperactivity disorder: a preliminary study. Neurology 57:423-430.
45. Munoz DP, Armstrong IT, Coe B (2007) Using eye movements to probe development and dysfunction, in Eye Movements: A Window on Mind and Brain (van Gompel RPG, Fischer MH, Murray WS, Hill RL eds), Elsevier, Oxford, UK, in press.
46. Munoz DP, Armstrong IT, Hampton KA, Moore KD (2003) Altered control of visual fixation and saccadic eye movements in attention-deficit hyperactivity disorder. J Neurophysiol 90:503-514.
47. Munoz DP, Broughton JR, Goldring JE, Armstrong IT (1998) Age-related performance of human subjects on saccadic eye movement tasks. Exp Brain Res 121:391-400.
48. Munoz DP, Dorris MC, Pare M, Everling S (2000) On your mark, get set: brainstem circuitry underlying saccadic initiation. Can J Physiol Pharmacol 78:934-944.
49. Munoz DP, Everling S (2004) Look away: the anti-saccade task and the voluntary control of eye movement. Nat Rev Neurosci 5:218-228.
50. Munoz DP, Schall JD (2004) Concurrent, Distributed Control of Saccad Initiation in the Frontal Eye Field and Superior Colliculus, in The Superior Colliculus: New Approaches for Studying Sensorimotor Integration (Hall WC, Moschovakis A, eds), pp 55-82. CRC Press, Boca Raton, FL.
51. Muri RM, Rivaud S, Gaymard B, Ploner CJ, Vermersch AI, Hess CW, Pierrot-Deseilligny C (1999) Role of the prefrontal cortex in the control of express saccades. A transcranial magnetic stimulation study. Neuropsychologia 37:199-206.
52. Nazir TA, Jacobs AM (1991) The effects of target discriminability and retinal eccentricity on saccade latencies: an analysis in terms of variable-criterion theory. Psychol Res 53:281-289.
53. O'Driscoll GA, Depatie L, Holahan AL, Savion-Lemieux T, Barr RG, Jolicoeur C, Douglas VI (2005) Executive functions and methylphenidate response in subtypes of attention-deficit/hyperactivity disorder. Biol Psychiatry 57:1452-1460.
54. Pare M, Munoz DP (1996) Saccadic reaction time in the monkey: advanced preparation of oculomotor programs is primarily responsible for express saccade occurrence. J Neurophysiol 76:3666-3681.
55. Pierrot-Deseilligny C, Milea D, Muri RM (2004) Eye movement control by the cerebral cortex. Curr Opin Neurol 17:17-25.
56. Rasmussen C (2005) Executive functioning and working memory in fetal alcohol spectrum disorder. Alcohol Clin Exp Res 29:1359-1367.
57. Ratcliff R (2006) A theory of memory retrieval. Psychoanal Rev 85:59-108.
58. Rivaud S, Muri RM, Gaymard B, Vermersch AI, Pierrot-Deseilligny C (1994) Eye movement disorders after frontal eye field lesions in humans. Exp Brain Res 102:110-120.
59. Salman MS, Sharpe JA, Eizenman M, Lillakas L, Westall C, To T, Dennis M, Steinbach MJ (2006) Saccades in children. Vision Res 46:1432-1439.
60. Schall JD (2004) On the role of frontal eye field in guiding attention and saccades. Vision Res 44:1453-1467.
61. Schonfeld AM, Mattson SN, Lang AR, Delis DC, Riley EP (2001) Verbal and nonverbal fluency in children with heavy prenatal alcohol exposure. J Stud Alcohol 62:239-246.
62. Scudder CA, Kaneko CS, Fuchs AF (2002) The brainstem burst generator for saccadic eye movements: a modern synthesis. Exp Brain Res 142:439-462.
63. Sommer MA, Tehovnik EJ (1997) Reversible inactivation of macaque frontal eye field. Exp Brain Res 116:229-249.
64. Sowell ER, Thompson PM, Mattson SN, Tessner KD, Jernigan TL, Riley EP, Toga AW (2002a) Regional brain shape abnormalities persist into adolescence after heavy prenatal alcohol exposure. Cereb Cortex 12:856-865.
65. Sowell ER, Thompson PM, Mattson SN, Tessner KD, Jernigan TL, Riley EP, Toga AW (2002b) Regional brain shape abnormalities persist into adolescence after heavy prenatal alcohol exposure. Cereb Cortex 12:856-865.
66. Sparks DL (2002) The brainstem control of saccadic eye movements. Nat Rev Neurosci 3:952-964.
67. Trappenberg TP, Dorris MC, Munoz DP, Klein RM (2001) A model of saccade initiation based on the competitive integration of exogenous and endogenous signals in the superior colliculus. J Cogn Neurosci 13:256-271.
68. Wass TS, Persutte WH, Hobbins JC (2001) The impact of prenatal alcohol exposure on frontal cortex development in utero. Am J Obstet Gynecol 185:737-742.
69. Willford JA, Luna B, Day NL (2005) Prenatal alcohol exposure impairs inhibitory and cognitive control in young adulthood. Alcohol Clin Exp Res 29:128A.
70. Zanelli J, Simon H, Rabe-Hesketh S, Walshe M, McDonald C, Murray RM, Maccabe JH (2005) Eye tracking in schizophrenia: does the antisaccade task measure anything that the smooth pursuit task does not. Psychiatry Res 136:181-188.