Reduced expression of the antiapoptotic proteins of Bcl-2 gene family in the lesional epidermis of patients with Darier's disease

Journal of Cutaneous Pathology

Volumn 34, Issue 3, 2007, Pages 234-238

  Pasmatzi, Efi ^a   Badavanis, George ^a   Monastirli, Alexandra ^a   Tsambaos, Dionysios ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2;

ADULT; APOPTOSIS; ARTICLE; CALCIUM DEPLETION; CONTROLLED STUDY; DARIER DISEASE; ENDOPLASMIC RETICULUM; EPIDERMIS; FEMALE; GENE MUTATION; GENODERMATOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PROTEIN EXPRESSION;

ADULT; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; EPIDERMIS; FEMALE; GENES, BCL-2; HUMANS; IMMUNOENZYME TECHNIQUES; KERATOSIS FOLLICULARIS; MALE; MIDDLE AGED;

EID: 33846898005     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2006.00600.x     Document Type: Article

References (19)

1. Munro CS. The phenotype of Darier's disease: penetrance and expressivity in adults and children. Br J Dermatol 1992; 127: 126.
2. 2+ pump, cause Darier disease. Nat Genet 1999; 21: 271.
3. Gniadecki R, Jemec GBE, Thomsen BM, Hansen M. Relationship between keratinocyte adhesion and death: anoikis in akantholytic diseases. Arch Dermatol Res 1998; 290: 528.
4. Wyllie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 68: 251.
5. Majno G & Joris I. Apoptosis, oncosis and necrosis. An overview of cell death. Am J Pathol 1995; 156: 3.
6. Hermiston ML & Gordon JI. In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J Cell Biol 1995; 129: 489.
7. Kuo TH, Kim HR, Zhu L, Yu Y, Lin HM, Tsang W. Modulation of endoplasmic reticulum calcium pump by Bcl-2. Oncogene 1998; 17: 1903.
8. 2+ and bax in cells undergoing apoptosis. J Biol Chem 2001; 276: 32257.
9. 2+ homeostasis by altering expression of inositol 1,4,5-triphosphate receptors. Proc Natl Acad Sci USA 2002; 99: 9830.
10. Monastirli A, Vourekas A, Badavanis G et al. Hsp27 expression coincides with epidermal stratification during human epidermal morphogenesis. Acta Derm Venereol 2005; 85: 389.
11. s-ATPases. J Biol Chem 1997; 272: 28815.
12. 2+-ATPase type 2 isoforms (SERCA2) in normal human skin and mucosa, and Darier's disease skin. Br J Dermatol 2002; 147: 670.
13. 2+ ATPase isoform b cause Darier's disease. J Invest Dermatol 2003; 121: 486.
14. Bongiorno MR & Arico M. The behaviour of Bcl-2, Bax and Bcl-x in Darier's disease. Br J Dermatol 2002; 147: 696.
15. Minn AJ, Kettlun CS, Liang H et al. Bcl-XL regulates apoptosis by heterodimerization-dependent and - independent mechanisms. EMBO J 1999; 18: 632.
16. Yajima H & Suzuki F. Identification of a Bcl-XL binding region within the ATPase domain of Apaf-1. Biochem Biophys Res Commun 2003; 309: 520.
17. White C, Li C, Yang J et al. The endoplasmic reticulum gateway to apoptosis by Bcl-XL modulation of the InsP3R. Nat Cell Biol 2005; 7: 1021.
18. Mikhailov V, Mikhailova M, Pulkrabek DJ, Dong Z, Venkatachalam MA, Saikumar P. Bcl-2 prevents Bax oligomerization in the mitochondrial outer membrane. J Biol Chem 2001; 276: 18361.
19. 2+ stores. J Biol Chem 2002; 277: 9219.