The behaviour of Bcl-2, Bax and Bcl-x in Darier's disease

British Journal of Dermatology

Volumn 147, Issue 4, 2002, Pages 696-700

  Bongiorno, Maria Rita ^a   Arico M ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

Apoptosis; Bax; Bcl 2; Bcl x; Darier's disease; SERCA2

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ION; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; SARCOENDOPLASMIC RETICULUM CALCIUM ATPASE 2; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CLINICAL ARTICLE; CONTROLLED STUDY; DARIER DISEASE; EPIDERMIS; EPIDERMIS CELL; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KERATINOCYTE; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FAMILY; PROTEIN FUNCTION; REGULATORY MECHANISM;

ADULT; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; EPIDERMIS; FEMALE; HUMANS; KERATINOCYTES; KERATOSIS FOLLICULARIS; MALE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0036408779     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2002.04963.x     Document Type: Article

References (24)

1. 2+ pump, cause Darier disease. Nat Genet 1999; 21: 271-7.
2. Takahashi H, Atsuta Y, Sato K et al. Novel mutations of ATP 'A' gene in Japanese patients of Darier's disease. J Dermatol Sci 2001; 26: 169-72.
3. 2+ ATPases. J Biol Chem 1997; 272: 28815-28.
4. Sakuntabhai A, Burge S, Monk S, Hovnanian A. Spectrum of novel ATP2A2 mutations in patients with Darier's disease. Hum Mol Genet 1999; 8: 1611-19.
5. 2+ ATPase, are associated with Brody disease. Nat Genet 1996; 14: 191-4.
6. 2+ ATPase gene cause deafness in the deafwaddler mice. Nat Genet 1998; 19: 390-4.
7. Jackisch C, Hahm HA, Tombal B et al. Delayed micromolar elevation in intracellular calcium precedes induction of apoptosis in thapsigargin-treated breast cancer cells. Clin Cancer Res 2000; 6: 2844-50.
8. Ma TS, Mann DL, Lee JH, Gallinghouse GJ. SR compartment calcium and cell apoptosis in SERCA overexpression. Cell Calcium 1999; 26: 25-36.
9. McConkey DJ, Orrenius S. The role of calcium in the regulation of apoptosis. Biochem Biophys Res Commun 1997; 239: 357-66.
10. He H, Lam M, McCormick TS, Distelhorst CW. Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2. J Cell Biol 1997; 138: 1219-28.
11. Shimizu S, Eguchi Y, Kamiika W et al. Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc Natl Acad Sci USA 1998; 95: 1455-9.
12. Wolter KY, Hsu YT, Smith CL et al. Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol 1997; 139: 1281-92.
13. 2+ responses. Science 1998; 280: 1763-6.
14. Hashimoto K, Fujiwara K, Harada M et al. Junctional proteins of keratinocytes in Grover's disease, Hailey-Hailey's disease and Darier's disease. J Dermatol 1995; 22: 159-70.
15. Metze D, Hamm H, Schorat A, Luger T. Involvement of the adherens junction-actin filament system in acantholytic dyskeratosis of Hailey-Hailey disease. A histological, ultrastructural, and histochemical study of lesional and non-lesional skin. J Cutan Pathol 1996; 23: 211-22.
16. Gniadecki R, Jemec GBE, Thomsen BM, Hansen M. Relationship between keratinocyte adhesion and death: Anoikis in acantholytic diseases. Arch Dermatol Res 1998; 290: 528-32.
17. Kowaleswski C, Mackiewicz W, Schmitt D et al. Cell-cell junctions in acantholytic diseases. Junction proteins in nonimmune and autoimmune acantholysis. Arch Dermatol Res 2001; 293: 1-11.
18. Stuart RO, Sun A, Bush KT, Nigam SK. Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium store. J Biol Chem 1996; 271: 13636-41.
19. Kane DJ, Sarafian TA, Anton R et al. Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species. Science 1993; 262: 1274-7.
20. Hockenbery DM, Oltvai ZN, Yin XM et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241-51.
21. Jacobson MD, Raff MC. Programmed cell death and Bcl-2 protection in very low oxygen. Nature 1995; 374: 814-16.
22. 2+. Oncogene 1996; 12: 2259-66.
23. Kuo TH, Kim HR, Zhu L et al. Modulation of endoplasmic reticulum calcium pump by Bcl-2. Oncogene 1998; 15: 1903-10.
24. Zhang QH, Sheng HP, Loh TT. Bcl-2 protects HL-60 cells from apoptosis by stabilizing their intracellular calcium pools. Life Sci 2001; 68: 2873-81.