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Volumn 120, Issue 3, 2007, Pages 424-432

Fcγ receptors are crucial for the expression of acquired resistance to virulent Salmonella enterica serovar Typhimurium in vivo but are not required for the induction of humoral or T-cell-mediated immunity

Author keywords

Antibody; Fc receptors; Immunity; Infection; Salmonella

Indexed keywords

ANTIBODY; FC RECEPTOR; LIVE VACCINE; SALMONELLOSIS VACCINE; BACTERIUM ANTIBODY;

EID: 33846897842     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2006.02527.x     Document Type: Article
Times cited : (22)

References (52)
  • 2
    • 0030807629 scopus 로고    scopus 로고
    • Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo
    • Richter-Dahlfors A, Buchan AMJ, Finlay BB. Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo. J Exp Med 1997; 186:569-80.
    • (1997) J Exp Med , vol.186 , pp. 569-580
    • Richter-Dahlfors, A.1    Buchan, A.M.J.2    Finlay, B.B.3
  • 3
    • 0011736531 scopus 로고
    • Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
    • Fields PI, Swanson RV, Haidaris CG, Heffron F. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc Natl Acad Sci USA 1986; 83:5189-93.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5189-5193
    • Fields, P.I.1    Swanson, R.V.2    Haidaris, C.G.3    Heffron, F.4
  • 4
    • 0032913015 scopus 로고    scopus 로고
    • Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium
    • Mastroeni P, Clare S, Khan S, Harrison JA, Hormaeche CE, Okamura H, Kurimoto M, Dougan G. Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium. Infect Immun 1999; 67:478-83.
    • (1999) Infect Immun , vol.67 , pp. 478-483
    • Mastroeni, P.1    Clare, S.2    Khan, S.3    Harrison, J.A.4    Hormaeche, C.E.5    Okamura, H.6    Kurimoto, M.7    Dougan, G.8
  • 5
    • 0026185217 scopus 로고
    • Serum TNF alpha in mouse typhoid and enhancement of a Salmonella infection by anti-TNF alpha antibodies
    • Mastroeni P, Arena A, Costa GB, Liberto MC, Bonina L, Hormaeche CE. Serum TNF alpha in mouse typhoid and enhancement of a Salmonella infection by anti-TNF alpha antibodies. Microb Pathog 1991; 11:33-8.
    • (1991) Microb Pathog , vol.11 , pp. 33-38
    • Mastroeni, P.1    Arena, A.2    Costa, G.B.3    Liberto, M.C.4    Bonina, L.5    Hormaeche, C.E.6
  • 6
    • 0030033426 scopus 로고    scopus 로고
    • Effect of interleukin 12 neutralization on host resistance and gamma interferon production in mouse typhoid
    • Mastroeni P, Harrison JA, Chabalgoity JA, Hormaeche CE. Effect of interleukin 12 neutralization on host resistance and gamma interferon production in mouse typhoid. Infect Immun 1996; 64:189-96.
    • (1996) Infect Immun , vol.64 , pp. 189-196
    • Mastroeni, P.1    Harrison, J.A.2    Chabalgoity, J.A.3    Hormaeche, C.E.4
  • 7
    • 0031707737 scopus 로고    scopus 로고
    • Interleukin-12 is required for control of the growth of attenuated aromatic-compound-dependent salmonellae in BALB/c mice: Role of gamma interferon and macrophage activation
    • Mastroeni P, Harrison JA, Robinson JH, Clare S, Khan S, Maskell DJ, Dougan G, Hormaeche CE. Interleukin-12 is required for control of the growth of attenuated aromatic-compound-dependent salmonellae in BALB/c mice: role of gamma interferon and macrophage activation. Infect Immun 1998; 66:4767-76.
    • (1998) Infect Immun , vol.66 , pp. 4767-4776
    • Mastroeni, P.1    Harrison, J.A.2    Robinson, J.H.3    Clare, S.4    Khan, S.5    Maskell, D.J.6    Dougan, G.7    Hormaeche, C.E.8
  • 8
    • 0031841730 scopus 로고    scopus 로고
    • Susceptibility to Salmonella typhimurium infection and effectiveness of vaccination in mice deficient in the tumor necrosis factor alpha p55 receptor
    • Everest P, Roberts M, Dougan G. Susceptibility to Salmonella typhimurium infection and effectiveness of vaccination in mice deficient in the tumor necrosis factor alpha p55 receptor. Infect Immun 1998; 66:3355-64.
    • (1998) Infect Immun , vol.66 , pp. 3355-3364
    • Everest, P.1    Roberts, M.2    Dougan, G.3
  • 9
    • 0025100394 scopus 로고
    • The role of IFN-gamma in murine Salmonella typhimurium infection
    • Muotiala A, Makela PH. The role of IFN-gamma in murine Salmonella typhimurium infection. Microb Pathog 1990; 8:135-41.
    • (1990) Microb Pathog , vol.8 , pp. 135-141
    • Muotiala, A.1    Makela, P.H.2
  • 10
    • 0027495106 scopus 로고
    • Role of gamma interferon in late stages of murine salmonellosis
    • Muotiala A, Makela PH. Role of gamma interferon in late stages of murine salmonellosis. Infect Immun 1993; 61:4248-53.
    • (1993) Infect Immun , vol.61 , pp. 4248-4253
    • Muotiala, A.1    Makela, P.H.2
  • 11
    • 0026354288 scopus 로고
    • Role of gamma interferon and tumor necrosis factor alpha in resistance to Salmonella typhimurium infection
    • Nauciel C, Espinasse-Maes F. Role of gamma interferon and tumor necrosis factor alpha in resistance to Salmonella typhimurium infection. Infect Immun 1992; 60:450-4.
    • (1992) Infect Immun , vol.60 , pp. 450-454
    • Nauciel, C.1    Espinasse-Maes, F.2
  • 12
    • 0036625997 scopus 로고    scopus 로고
    • Immunity to systemic Salmonella infections
    • Mastroeni P. Immunity to systemic Salmonella infections. Current Mol Med 2002; 2:393-406.
    • (2002) Current Mol Med , vol.2 , pp. 393-406
    • Mastroeni, P.1
  • 13
    • 0012061574 scopus 로고    scopus 로고
    • Endogenous IL-15 might be responsible for early protection by natural killer cells against infection with an avirulent strain of Salmonella choleraesuis in mice
    • Hirose K, Nishimura H, Matsuguchi T, Yoshikai Y. Endogenous IL-15 might be responsible for early protection by natural killer cells against infection with an avirulent strain of Salmonella choleraesuis in mice. J Leukoc Biol 1999; 66:382-90.
    • (1999) J Leukoc Biol , vol.66 , pp. 382-390
    • Hirose, K.1    Nishimura, H.2    Matsuguchi, T.3    Yoshikai, Y.4
  • 14
    • 0018308610 scopus 로고
    • The natural resistance of radiation chimeras to S. typhimurium C5
    • Hormaeche CE. The natural resistance of radiation chimeras to S. typhimurium C5. Immunology 1979; 37:329-32.
    • (1979) Immunology , vol.37 , pp. 329-332
    • Hormaeche, C.E.1
  • 15
    • 0025329138 scopus 로고
    • T cells do not mediate the initial suppression of a Salmonella infection in the RES
    • Hormaeche CE, Mastroeni P, Arena A, Uddin J, Joysey HS. T cells do not mediate the initial suppression of a Salmonella infection in the RES. Immunology 1990; 70:247-50.
    • (1990) Immunology , vol.70 , pp. 247-250
    • Hormaeche, C.E.1    Mastroeni, P.2    Arena, A.3    Uddin, J.4    Joysey, H.S.5
  • 16
    • 0029886029 scopus 로고    scopus 로고
    • + TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location
    • + TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location. J Immunol 1996; 156:3321-6.
    • (1996) J Immunol , vol.156 , pp. 3321-3326
    • Hess, J.1    Ladel, C.2    Miko, D.3    Kaufmann, S.H.4
  • 17
    • 0025150320 scopus 로고
    • + T cells and T-independent mechanisms in acquired resistance to Salmonella typhimurium infection
    • + T cells and T-independent mechanisms in acquired resistance to Salmonella typhimurium infection. J Immunol 1990; 145:1265-9.
    • (1990) J Immunol , vol.145 , pp. 1265-1269
    • Nauciel, C.1
  • 18
    • 0027185279 scopus 로고
    • Adoptive transfer of immunity to oral challenge with virulent salmonellae in innately susceptible BALB/c mice requires both immune serum and T cells
    • Mastroeni P, Villarreal-Ramos B, Hormaeche CE. Adoptive transfer of immunity to oral challenge with virulent salmonellae in innately susceptible BALB/c mice requires both immune serum and T cells. Infect Immun 1993; 61:3981-4.
    • (1993) Infect Immun , vol.61 , pp. 3981-3984
    • Mastroeni, P.1    Villarreal-Ramos, B.2    Hormaeche, C.E.3
  • 20
    • 0345363054 scopus 로고    scopus 로고
    • Value of a single-tube widal test in diagnosis of typhoid fever in Vietnam
    • Parry CM, Hoa NT, Diep TS et al. Value of a single-tube widal test in diagnosis of typhoid fever in Vietnam. J Clin Microbiol 1999; 37:2882-6.
    • (1999) J Clin Microbiol , vol.37 , pp. 2882-2886
    • Parry, C.M.1    Hoa, N.T.2    Diep, T.S.3
  • 21
    • 0031969678 scopus 로고    scopus 로고
    • Quantitation of bacteria in blood of typhoid fever patients and relationship between counts and clinical features, transmissibility, and antibiotic resistance
    • Wain J, Diep TS, Ho VA, Walsh AM, Nguyen TT, Parry CM, White NJ. Quantitation of bacteria in blood of typhoid fever patients and relationship between counts and clinical features, transmissibility, and antibiotic resistance. J Clin Microbiol 1998; 36:1683-7.
    • (1998) J Clin Microbiol , vol.36 , pp. 1683-1687
    • Wain, J.1    Diep, T.S.2    Ho, V.A.3    Walsh, A.M.4    Nguyen, T.T.5    Parry, C.M.6    White, N.J.7
  • 22
    • 0016064933 scopus 로고
    • The route of enteric infection in normal mice
    • Carter PB, Collins FM. The route of enteric infection in normal mice. J Exp Med 1974; 139:1189-203.
    • (1974) J Exp Med , vol.139 , pp. 1189-1203
    • Carter, P.B.1    Collins, F.M.2
  • 23
    • 1642330260 scopus 로고    scopus 로고
    • Salmonella infections in the mouse model: Host resistance factors and in vivo dynamics of bacterial spread and distribution in the tissues
    • Mastroeni P, Sheppard M. Salmonella infections in the mouse model: host resistance factors and in vivo dynamics of bacterial spread and distribution in the tissues. Microbes Infect 2004; 6:398-405.
    • (2004) Microbes Infect , vol.6 , pp. 398-405
    • Mastroeni, P.1    Sheppard, M.2
  • 24
    • 0035057022 scopus 로고    scopus 로고
    • Ravetch JV, Bolland S. IgG Fc receptors. Annu Rev Immunol 2001; 19:275-90.
    • Ravetch JV, Bolland S. IgG Fc receptors. Annu Rev Immunol 2001; 19:275-90.
  • 25
    • 22544487815 scopus 로고    scopus 로고
    • FcγRIV. A novel FcR with distinct IGg subclass specificity
    • Nimmerjahn F, Bruhns P, Horiuchi K, Ravetch JV. FcγRIV. A novel FcR with distinct IGg subclass specificity. Immunity 2005; 23:41-51.
    • (2005) Immunity , vol.23 , pp. 41-51
    • Nimmerjahn, F.1    Bruhns, P.2    Horiuchi, K.3    Ravetch, J.V.4
  • 27
    • 0034679577 scopus 로고    scopus 로고
    • Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro
    • Vazquez-Torres A, Jones-Carson J, Mastroeni P, Ischiropoulos H, Fang FC. Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro. J Exp Med 2000; 192:227-36.
    • (2000) J Exp Med , vol.192 , pp. 227-236
    • Vazquez-Torres, A.1    Jones-Carson, J.2    Mastroeni, P.3    Ischiropoulos, H.4    Fang, F.C.5
  • 28
    • 0034679699 scopus 로고    scopus 로고
    • Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. II. Effects on microbial proliferation and host survival in vivo
    • Mastroeni P, Vazquez-Torres A, Fang FC, Xu Y, Khan S, Hormaeche CE, Dougan G. Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. II. Effects on microbial proliferation and host survival in vivo. J Exp Med 2000; 192:237-48.
    • (2000) J Exp Med , vol.192 , pp. 237-248
    • Mastroeni, P.1    Vazquez-Torres, A.2    Fang, F.C.3    Xu, Y.4    Khan, S.5    Hormaeche, C.E.6    Dougan, G.7
  • 29
    • 33748753316 scopus 로고    scopus 로고
    • Effect of immune serum and role of individual Fcgamma receptors on the intracellular distribution and survival of Salmonella enterica serovar Typhimurium in murine macrophages
    • Uppington H, Menager N, Boross P, Wood J, Sheppard M, Verbeek S, Mastroeni P. Effect of immune serum and role of individual Fcgamma receptors on the intracellular distribution and survival of Salmonella enterica serovar Typhimurium in murine macrophages. Immunology 2006; 119:147-58.
    • (2006) Immunology , vol.119 , pp. 147-158
    • Uppington, H.1    Menager, N.2    Boross, P.3    Wood, J.4    Sheppard, M.5    Verbeek, S.6    Mastroeni, P.7
  • 30
    • 0019407618 scopus 로고
    • Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
    • Hoiseth SK, Stocker BA. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 1981; 291:238-9.
    • (1981) Nature , vol.291 , pp. 238-239
    • Hoiseth, S.K.1    Stocker, B.A.2
  • 31
    • 0018294108 scopus 로고
    • Natural resistance to Salmonella typhimurium in different inbred mouse strains
    • Hormaeche CE. Natural resistance to Salmonella typhimurium in different inbred mouse strains. Immunology 1979; 37:311-18.
    • (1979) Immunology , vol.37 , pp. 311-318
    • Hormaeche, C.E.1
  • 32
    • 0026935285 scopus 로고
    • Proliferative and T-cell specific interleukin (IL-2/IL-4) production responses in spleen cells from mice vaccinated with aroA live attenuated Salmonella vaccines
    • Villarreal B, Mastroeni P, de Hormaeche RD, Hormaeche CE. Proliferative and T-cell specific interleukin (IL-2/IL-4) production responses in spleen cells from mice vaccinated with aroA live attenuated Salmonella vaccines. Microb Pathog 1992; 13:305-15.
    • (1992) Microb Pathog , vol.13 , pp. 305-315
    • Villarreal, B.1    Mastroeni, P.2    de Hormaeche, R.D.3    Hormaeche, C.E.4
  • 33
    • 0023940990 scopus 로고
    • Gonococcal variants selected by growth in vivo or in vitro have antigenically different LPS
    • Demarco de Hormaeche R, Jessop H, Senior K. Gonococcal variants selected by growth in vivo or in vitro have antigenically different LPS. Microb Pathog 1988; 4:289-97.
    • (1988) Microb Pathog , vol.4 , pp. 289-297
    • Demarco de Hormaeche, R.1    Jessop, H.2    Senior, K.3
  • 34
    • 0030929805 scopus 로고    scopus 로고
    • Fc receptor biology
    • Daeron M. Fc receptor biology. Annu Rev Immunol 1997; 15:203-34.
    • (1997) Annu Rev Immunol , vol.15 , pp. 203-234
    • Daeron, M.1
  • 35
    • 0026017326 scopus 로고
    • Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies
    • Manca F, Fenoglio D, Li Pira G, Kunkl A, Celada F. Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies. J Exp Med 1991; 173:37-48.
    • (1991) J Exp Med , vol.173 , pp. 37-48
    • Manca, F.1    Fenoglio, D.2    Li Pira, G.3    Kunkl, A.4    Celada, F.5
  • 37
    • 4644333888 scopus 로고    scopus 로고
    • Salmonella escape from antigen presentation can be overcome by targeting bacteria to Fc gamma receptors on dendritic cells
    • Tobar JA, Gonzalez PA, Kalergis AM. Salmonella escape from antigen presentation can be overcome by targeting bacteria to Fc gamma receptors on dendritic cells. J Immunol 2004; 173:4058-65.
    • (2004) J Immunol , vol.173 , pp. 4058-4065
    • Tobar, J.A.1    Gonzalez, P.A.2    Kalergis, A.M.3
  • 39
    • 0029915320 scopus 로고    scopus 로고
    • Protection against oral challenge three months after i.v. Immunization of BALB/c mice with live Aro Salmonella typhimurium and Salmonella enteritidis vaccines is serotype (species)-dependent and only partially determined by the main LPS O antigen
    • Hormaeche CE, Mastroeni P, Harrison JA. Demarco de Hormaeche R, Svenson S, Stocker BA. Protection against oral challenge three months after i.v. Immunization of BALB/c mice with live Aro Salmonella typhimurium and Salmonella enteritidis vaccines is serotype (species)-dependent and only partially determined by the main LPS O antigen. Vaccine 1996; 14:251-9.
    • (1996) Vaccine , vol.14 , pp. 251-259
    • Hormaeche, C.E.1    Mastroeni, P.2    Harrison, J.A.3    Demarco de Hormaeche, R.4    Svenson, S.5    Stocker, B.A.6
  • 40
    • 0026147350 scopus 로고
    • A 'safe-site' for Salmonella typhimurium is within splenic cells during the early phase of infection in mice
    • Dunlap NE, Benjamin WH Jr, McCall RD Jr, Tilden AB. Briles DE. A 'safe-site' for Salmonella typhimurium is within splenic cells during the early phase of infection in mice. Microb Pathog 1991; 10:297-310.
    • (1991) Microb Pathog , vol.10 , pp. 297-310
    • Dunlap, N.E.1    Benjamin Jr, W.H.2    McCall Jr, R.D.3    Tilden, A.B.4    Briles, D.E.5
  • 41
    • 0034741924 scopus 로고    scopus 로고
    • In vivo activation of dendritic cells and T cells during Salmonella enterica serovar Typhimurium infection
    • Yrlid U, Svensson M, Hakansson A, Chambers BJ, Ljunggren HG, Wick MJ. In vivo activation of dendritic cells and T cells during Salmonella enterica serovar Typhimurium infection. Infect Immun 2001; 69:5726-35.
    • (2001) Infect Immun , vol.69 , pp. 5726-5735
    • Yrlid, U.1    Svensson, M.2    Hakansson, A.3    Chambers, B.J.4    Ljunggren, H.G.5    Wick, M.J.6
  • 42
    • 0034848892 scopus 로고    scopus 로고
    • Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo
    • Salcedo SP, Noursadeghi M, Cohen J, Holden DW. Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo. Cell Microbiol 2001; 3:587-97.
    • (2001) Cell Microbiol , vol.3 , pp. 587-597
    • Salcedo, S.P.1    Noursadeghi, M.2    Cohen, J.3    Holden, D.W.4
  • 43
    • 0031601954 scopus 로고    scopus 로고
    • Comparative effect of gentamicin and pefloxacin treatment on the late stages of mouse typhoid
    • Bonina L, Costa GB, Mastroeni P. Comparative effect of gentamicin and pefloxacin treatment on the late stages of mouse typhoid. New Microbiol 1998; 21:9-14.
    • (1998) New Microbiol , vol.21 , pp. 9-14
    • Bonina, L.1    Costa, G.B.2    Mastroeni, P.3
  • 44
    • 18344370440 scopus 로고    scopus 로고
    • FcγRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection
    • Ioan-Facsinay A, de Kimpe SJ, Hellwig SM et al. FcγRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 2002; 16:391-402.
    • (2002) Immunity , vol.16 , pp. 391-402
    • Ioan-Facsinay, A.1    de Kimpe, S.J.2    Hellwig, S.M.3
  • 45
    • 0026587743 scopus 로고
    • CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes
    • Carter RH, Fearon DT. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 1992; 256:105-7.
    • (1992) Science , vol.256 , pp. 105-107
    • Carter, R.H.1    Fearon, D.T.2
  • 46
    • 0033559145 scopus 로고    scopus 로고
    • Modulation of the humoral immune response by antibody-mediated antigen targeting to complement receptors and Fc receptors
    • Baiu DC, Prechl J, Tchorbanov A, Molina HD, Erdei A, Sulica A, Capel PJ, Hazenbos WL. Modulation of the humoral immune response by antibody-mediated antigen targeting to complement receptors and Fc receptors. J Immunol 1999; 162:3125-30.
    • (1999) J Immunol , vol.162 , pp. 3125-3130
    • Baiu, D.C.1    Prechl, J.2    Tchorbanov, A.3    Molina, H.D.4    Erdei, A.5    Sulica, A.6    Capel, P.J.7    Hazenbos, W.L.8
  • 47
    • 0032534584 scopus 로고    scopus 로고
    • Complement opsonization is required for presentation of immune complexes by resting peripheral blood B cells
    • Boackle SA, Morris MA, Holers VM, Karp DR. Complement opsonization is required for presentation of immune complexes by resting peripheral blood B cells. J Immunol 1998; 161:6537-43.
    • (1998) J Immunol , vol.161 , pp. 6537-6543
    • Boackle, S.A.1    Morris, M.A.2    Holers, V.M.3    Karp, D.R.4
  • 48
    • 0032147101 scopus 로고    scopus 로고
    • CD21/CD35 in B cell activation
    • Carroll MC. CD21/CD35 in B cell activation. Semin Immunol 1998; 10:279-86.
    • (1998) Semin Immunol , vol.10 , pp. 279-286
    • Carroll, M.C.1
  • 49
    • 0029994402 scopus 로고    scopus 로고
    • Function of C3 in a humoral response: IC3b/C3dg bound to an immune complex generated with natural antibody and a primary antigen promotes antigen uptake and the expression of co-stimulatory molecules by all B cells, but only stimulates immunoglobulin synthesis by antigen-specific B cells
    • Thornton BP, Vetvicka V, Ross GD. Function of C3 in a humoral response: iC3b/C3dg bound to an immune complex generated with natural antibody and a primary antigen promotes antigen uptake and the expression of co-stimulatory molecules by all B cells, but only stimulates immunoglobulin synthesis by antigen-specific B cells. Clin Exp Immunol 1996; 104:531-7.
    • (1996) Clin Exp Immunol , vol.104 , pp. 531-537
    • Thornton, B.P.1    Vetvicka, V.2    Ross, G.D.3
  • 50
    • 0033964726 scopus 로고    scopus 로고
    • -/- (B-cell-deficient) mice fail to mount solid acquired resistance to oral challenge with virulent Salmonella enterica serovar Typhimurium and show impaired Th1 T-cell responses to Salmonella antigens
    • -/- (B-cell-deficient) mice fail to mount solid acquired resistance to oral challenge with virulent Salmonella enterica serovar Typhimurium and show impaired Th1 T-cell responses to Salmonella antigens. Infect Immun 2000; 68:46-53.
    • (2000) Infect Immun , vol.68 , pp. 46-53
    • Mastroeni, P.1    Simmons, C.2    Fowler, R.3    Hormaeche, C.E.4    Dougan, G.5
  • 52
    • 1542313883 scopus 로고    scopus 로고
    • FcγRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis
    • Clatworthy MR, Smith KG. FcγRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis. J Exp Med 2004; 199:717-23.
    • (2004) J Exp Med , vol.199 , pp. 717-723
    • Clatworthy, M.R.1    Smith, K.G.2


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