Function of C3 in a humoral response: IC3b/C3dg bound to an immune complex generated with natural antibody and a primary antigen promotes antigen uptake and the expression of co-stimulatory molecules by all B cells, but only stimulates immunoglobulin synthesis by antigen-specific B cells

Clinical and Experimental Immunology

Volumn 104, Issue 3, 1996, Pages 531-537

  Thornton, B P ^a   Vetvicka V ^a   Ross, G D ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

B lymphocytes; C3; CD80; CR2 CD21; LFA 1 CD11a

Indexed keywords

CD8 ANTIGEN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3D; ENDOGENOUS COMPOUND; FC RECEPTOR; KEYHOLE LIMPET HEMOCYANIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; TETANUS TOXOID;

ADULT; ANTIGEN ANTIBODY COMPLEX; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOGLOBULIN PRODUCTION; NORMAL HUMAN; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; ANTIGEN-ANTIBODY COMPLEX; B-LYMPHOCYTES; CELLS, CULTURED; COMPLEMENT C3B; COMPLEMENT C3D; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEMOCYANIN; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; RECEPTORS, COMPLEMENT 3D; RECEPTORS, IGG;

EID: 0029994402     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.57761.x     Document Type: Article

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