메뉴 건너뛰기




Volumn 4, Issue 5, 2006, Pages 220-226

Cultivated black cumin: Nigella sativa L. (Ranunculaceae);La nigelle cultivée: Nigella sativa L. (Ranunculaceae)

Author keywords

Nigella sativa; Pharmacological actions; Seeds; Thymoquinone; Toxicity

Indexed keywords

ACETYLSALICYLIC ACID; ALKALOID; ALPHA HEDERINE; CISPLATIN; DITHYMOQUINONE; ESSENTIAL OIL; NIGELLA SATIVA EXTRACT; NIGELLICINE; NIGELLIMINE; SAPONIN; THYMOHYDROQUINONE; THYMOL; THYMOQUINONE; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

EID: 33846896451     PISSN: 16248597     EISSN: 17652847     Source Type: Journal    
DOI: 10.1007/s10298-006-0187-1     Document Type: Article
Times cited : (10)

References (77)
  • 1
    • 0034648056 scopus 로고    scopus 로고
    • Antinociceptive effects of Nigella sativa oil and its major components in mice
    • Abdel Fatah M, Matsumoto K, Watanake H (2000) Antinociceptive effects of Nigella sativa oil and its major components in mice. Eur J Pharmacol 400: 89-97
    • (2000) Eur J Pharmacol , vol.400 , pp. 89-97
    • Abdel Fatah, M.1    Matsumoto, K.2    Watanake, H.3
  • 2
    • 0018611973 scopus 로고
    • Antimicrobial and anthelmintic activities of the essential oil of Nigella sativa Linn
    • Agrawal R, Kharya MD, Shrivastava R (1979) Antimicrobial and anthelmintic activities of the essential oil of Nigella sativa Linn. Indian J Exp Biol 17: 1264-1265
    • (1979) Indian J Exp Biol , vol.17 , pp. 1264-1265
    • Agrawal, R.1    Kharya, M.D.2    Shrivastava, R.3
  • 4
    • 0030037348 scopus 로고    scopus 로고
    • Antiulcer effects of aqueous extracts of Nigella sativa and Pongamia pinnata in rats
    • Akhtar AH, Ahmad KD, Gilani SN, et al. (1996) Antiulcer effects of aqueous extracts of Nigella sativa and Pongamia pinnata in rats. Fitoterapia 38: 195-199
    • (1996) Fitoterapia , vol.38 , pp. 195-199
    • Akhtar, A.H.1    Ahmad, K.D.2    Gilani, S.N.3
  • 5
    • 0026269341 scopus 로고
    • The effect of a plant mixture extract on liver gluconeogenesis in streptozotocin induced diabetic rats
    • AI-Awadi F, Fatania H, Shamte U (1991) The effect of a plant mixture extract on liver gluconeogenesis in streptozotocin induced diabetic rats. Diab Res 18: 163-168
    • (1991) Diab Res , vol.18 , pp. 163-168
    • AI-Awadi, F.1    Fatania, H.2    Shamte, U.3
  • 6
    • 0034987355 scopus 로고    scopus 로고
    • The anti-inflammatory, analgesic and anti-pyretic activity of Nigella sativa
    • AI-Ghamdi MS (2001) The anti-inflammatory, analgesic and anti-pyretic activity of Nigella sativa. J Ethnopharmacol 76: 45-48
    • (2001) J Ethnopharmacol , vol.76 , pp. 45-48
    • AI-Ghamdi, M.S.1
  • 7
    • 0027309568 scopus 로고
    • Hypoglycemic effects of the volatile oil of Nigella sativa seeds
    • AI-Hader A, Aqel M, Hasan Z (1993) Hypoglycemic effects of the volatile oil of Nigella sativa seeds. Int J Pharmacog 31: 96-100
    • (1993) Int J Pharmacog , vol.31 , pp. 96-100
    • AI-Hader, A.1    Aqel, M.2    Hasan, Z.3
  • 8
    • 24644476612 scopus 로고    scopus 로고
    • Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone
    • Aljabre SHM, Randhawa MA, Akhtar N, et al. (2005) Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone. J Ethnopharmacol 101: 116-119
    • (2005) J Ethnopharmacol , vol.101 , pp. 116-119
    • Aljabre, S.H.M.1    Randhawa, M.A.2    Akhtar, N.3
  • 9
    • 29744465529 scopus 로고    scopus 로고
    • Levels of selenium, DL-α-tocopherol, DL-γ-tocopherol, all-trans-retinol, thymoquinone and thymol in different brands of Nigella sativa seeds
    • Al-Saleh IA, Billedo G, El-Doush II (2006) Levels of selenium, DL-α-tocopherol, DL-γ-tocopherol, all-trans-retinol, thymoquinone and thymol in different brands of Nigella sativa seeds. Journal of Food Composition and Analysis 19: 167-175
    • (2006) Journal of Food Composition and Analysis , vol.19 , pp. 167-175
    • Al-Saleh, I.A.1    Billedo, G.2    El-Doush II3
  • 10
    • 23844532345 scopus 로고    scopus 로고
    • Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylene-tetrazol- induced kindling in mice
    • Ilhan A, Gurel A, Armutcu F, et al. (2005) Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylene-tetrazol- induced kindling in mice. Neuropharmacology 49: 456-464
    • (2005) Neuropharmacology , vol.49 , pp. 456-464
    • Ilhan, A.1    Gurel, A.2    Armutcu, F.3
  • 11
    • 33846931504 scopus 로고    scopus 로고
    • Atta-ur-Rahman, Malik S, Ahmed S, et al. (1985) Nigellimine-N-oxide a new isoquinoline alkaloid from the seeds of Nigella sativa. Heterocycles 23: 953-955
    • Atta-ur-Rahman, Malik S, Ahmed S, et al. (1985) Nigellimine-N-oxide a new isoquinoline alkaloid from the seeds of Nigella sativa. Heterocycles 23: 953-955
  • 12
    • 0021886538 scopus 로고    scopus 로고
    • Atta-ur-Rahman, Malik S, Cun-heng H, et al. (1985) Isolation and structure determination of nigellicine, a novel alkaloid from the seeds of Nigella sativa. Tetrahedron Lett 23: 2759-2762
    • Atta-ur-Rahman, Malik S, Cun-heng H, et al. (1985) Isolation and structure determination of nigellicine, a novel alkaloid from the seeds of Nigella sativa. Tetrahedron Lett 23: 2759-2762
  • 13
    • 0028954707 scopus 로고    scopus 로고
    • Atta-ur-Rahman, Malik S, Hasan SS, et al. (1995) Nigellidine, a new indazole alkaloid from the seeds of Nigella sativa. Tetrahedron Lett 36: 1993-1996
    • Atta-ur-Rahman, Malik S, Hasan SS, et al. (1995) Nigellidine, a new indazole alkaloid from the seeds of Nigella sativa. Tetrahedron Lett 36: 1993-1996
  • 14
    • 0026683271 scopus 로고    scopus 로고
    • Atta-ur-Rahman, Malik S, Zaman K (1992) Nigellimine, a new isoquinoline alkaloid from the seeds of Nigella sativa. J Nat Prod 55: 676-678
    • Atta-ur-Rahman, Malik S, Zaman K (1992) Nigellimine, a new isoquinoline alkaloid from the seeds of Nigella sativa. J Nat Prod 55: 676-678
  • 15
    • 0031431309 scopus 로고    scopus 로고
    • Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity
    • Badary OA, Nagi MN, AI-Shabanah OA, et al. (1997) Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Can J Physiol Pharmacol 75: 1356-1361
    • (1997) Can J Physiol Pharmacol , vol.75 , pp. 1356-1361
    • Badary, O.A.1    Nagi, M.N.2    AI-Shabanah, O.A.3
  • 16
    • 0031680253 scopus 로고    scopus 로고
    • Acute and subchronic toxicity of thymoquinone in mice
    • Badary OA, AI-Shabanah OA, Nagi MN, et al. (1998) Acute and subchronic toxicity of thymoquinone in mice. Drug Develop Res 44: 56-61
    • (1998) Drug Develop Res , vol.44 , pp. 56-61
    • Badary, O.A.1    AI-Shabanah, O.A.2    Nagi, M.N.3
  • 17
    • 0033379794 scopus 로고    scopus 로고
    • Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone
    • Badary OA, AI-Shabanah OA, Nagi MN, et al. (1999) Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone. Eur J Cancer Prev 8: 435-440
    • (1999) Eur J Cancer Prev , vol.8 , pp. 435-440
    • Badary, O.A.1    AI-Shabanah, O.A.2    Nagi, M.N.3
  • 18
    • 0035237915 scopus 로고    scopus 로고
    • Inhibitory effects of thymoquinone against 20-methylcholantherene-induced fibrosarcoma tumorigenesis
    • Badary OA, Gamal AM (2001) Inhibitory effects of thymoquinone against 20-methylcholantherene-induced fibrosarcoma tumorigenesis. Cancer Detec Prev 25: 362-368
    • (2001) Cancer Detec Prev , vol.25 , pp. 362-368
    • Badary, O.A.1    Gamal, A.M.2
  • 21
    • 33846932237 scopus 로고    scopus 로고
    • Bouquet J (1921) Matière médicale indigène de l'Afrique du Nord. Trav. Off. Nat. Matières premières végétales. Notice 8: 1-29
    • Bouquet J (1921) Matière médicale indigène de l'Afrique du Nord. Trav. Off. Nat. Matières premières végétales. Notice 8: 1-29
  • 22
    • 0033837710 scopus 로고    scopus 로고
    • Antioxidant activity of Nigella sativa essential oil
    • Burits M, Bucar F (2000) Antioxidant activity of Nigella sativa essential oil. Phytother Res 14: 323-328
    • (2000) Phytother Res , vol.14 , pp. 323-328
    • Burits, M.1    Bucar, F.2
  • 23
    • 0000959715 scopus 로고
    • The pharmacologically active principle in Nigella sativa
    • Canonica L, Jommi G, Scolastico C, et al. (1963) The pharmacologically active principle in Nigella sativa. Gazz Chim Ital 93(11): 1404-1407
    • (1963) Gazz Chim Ital , vol.93 , Issue.11 , pp. 1404-1407
    • Canonica, L.1    Jommi, G.2    Scolastico, C.3
  • 24
    • 0027528479 scopus 로고
    • Inhibition of histamine release from mast cells by nigellone
    • Chakravarty N (1993) Inhibition of histamine release from mast cells by nigellone. Ann Allergy 70: 237-242
    • (1993) Ann Allergy , vol.70 , pp. 237-242
    • Chakravarty, N.1
  • 25
    • 0032584004 scopus 로고    scopus 로고
    • Hepatoprotective activity of thymoquinone in isolated rat hepatocytes
    • Daba MH, Abdel Rahman MS (1998) Hepatoprotective activity of thymoquinone in isolated rat hepatocytes. Toxicol Lett 95: 23-29
    • (1998) Toxicol Lett , vol.95 , pp. 23-29
    • Daba, M.H.1    Abdel Rahman, M.S.2
  • 27
    • 0037298005 scopus 로고    scopus 로고
    • Gastroprotective activity of Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia reperfusion in rats
    • El-Abhar HS, Abdullah DM, Saleh S (2003) Gastroprotective activity of Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia reperfusion in rats. J Ethnopharmacol 84: 251-258
    • (2003) J Ethnopharmacol , vol.84 , pp. 251-258
    • El-Abhar, H.S.1    Abdullah, D.M.2    Saleh, S.3
  • 28
    • 0000988920 scopus 로고
    • Studies on the chemical constituents of Egyptian Nigella sativa L. seeds. The essential oil
    • EI-Dakhakhny M (1963) Studies on the chemical constituents of Egyptian Nigella sativa L. seeds. The essential oil. Planta Med 11: 465-470
    • (1963) Planta Med , vol.11 , pp. 465-470
    • EI-Dakhakhny, M.1
  • 29
    • 0034284791 scopus 로고    scopus 로고
    • EI-Dakhakhny M, Barakat M, Abd EI-Halim, et al. (2000) Effect of Nigella sativa oil on gastric secretion and ethanol induced ulcer in rats. J Ethnopharmacol 72: 299-304
    • EI-Dakhakhny M, Barakat M, Abd EI-Halim, et al. (2000) Effect of Nigella sativa oil on gastric secretion and ethanol induced ulcer in rats. J Ethnopharmacol 72: 299-304
  • 30
    • 0033800305 scopus 로고    scopus 로고
    • Nigella sativa L. protects against induced hepatotoxicity and improves serum lipid profile in rats
    • EI-Dakhakhny M, Mady NI, Halim MA (2000) Nigella sativa L. protects against induced hepatotoxicity and improves serum lipid profile in rats. Arzneimittelforsch 50: 832-836
    • (2000) Arzneimittelforsch , vol.50 , pp. 832-836
    • EI-Dakhakhny, M.1    Mady, N.I.2    Halim, M.A.3
  • 31
    • 0036273437 scopus 로고    scopus 로고
    • The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions
    • EI-Dakhakhny M, Mady NI, Lembert N, et al. (2002) The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions. Planta Med 65: 465-466
    • (2002) Planta Med , vol.65 , pp. 465-466
    • EI-Dakhakhny, M.1    Mady, N.I.2    Lembert, N.3
  • 32
    • 0036277862 scopus 로고    scopus 로고
    • Nigella sativa oil, nigellone and derived thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats
    • EI-Dakhakhny M, Mady NI, Lembert N, et al. (2002) Nigella sativa oil, nigellone and derived thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats. J Ethnopharmacol 81(2): 161-164
    • (2002) J Ethnopharmacol , vol.81 , Issue.2 , pp. 161-164
    • EI-Dakhakhny, M.1    Mady, N.I.2    Lembert, N.3
  • 33
    • 0031863041 scopus 로고    scopus 로고
    • Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in rats
    • El Daly ES (1998) Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in rats. J Pharm Bel 53: 87-95
    • (1998) J Pharm Bel , vol.53 , pp. 87-95
    • El Daly, E.S.1
  • 34
    • 0038713648 scopus 로고
    • The black seed (Nigella sativa) and immunity: Its effect on human Tcell subset
    • EI-Kadi A, Kandil O (1987) The black seed (Nigella sativa) and immunity: its effect on human Tcell subset. Fed Proc 46: 1222
    • (1987) Fed Proc , vol.46 , pp. 1222
    • EI-Kadi, A.1    Kandil, O.2
  • 36
    • 0031932976 scopus 로고    scopus 로고
    • Anti-bacterial properties of essential oils from Nigella sativa seeds, Cymbopogon citatus leaves and Pulicaria undulata aerial parts
    • EI-Kamali HH, Ahmed AH, Mohammed AS, et al. (1998) Anti-bacterial properties of essential oils from Nigella sativa seeds, Cymbopogon citatus leaves and Pulicaria undulata aerial parts. Fitoterapia 34: 77-78
    • (1998) Fitoterapia , vol.34 , pp. 77-78
    • EI-Kamali, H.H.1    Ahmed, A.H.2    Mohammed, A.S.3
  • 37
    • 10344235988 scopus 로고    scopus 로고
    • Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism
    • El-Mahmoudy A, Shimizu Y, Shiina T, et al. (2005) Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism. Int Immunopharmacol 5(1): 195-207
    • (2005) Int Immunopharmacol , vol.5 , Issue.1 , pp. 195-207
    • El-Mahmoudy, A.1    Shimizu, Y.2    Shiina, T.3
  • 38
    • 0027290046 scopus 로고
    • The respiratory effects of the volatile oil of the black seed (Nigella sativa) in guinea pigs: Elucidation of the mechanism(s) of action
    • EI-Tahir KE, Ashour MM, AI-Harbi MM (1993) The respiratory effects of the volatile oil of the black seed (Nigella sativa) in guinea pigs: elucidation of the mechanism(s) of action. Gen Pharmacol 24: 1115-1122
    • (1993) Gen Pharmacol , vol.24 , pp. 1115-1122
    • EI-Tahir, K.E.1    Ashour, M.M.2    AI-Harbi, M.M.3
  • 39
    • 0027264732 scopus 로고
    • The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: Elucidation of the mechanism of action
    • EI-Tahir KE, Ashour MM, AI-Harbi MM (1993) The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: elucidation of the mechanism of action. Gen Pharmacol 24: 1123-1131
    • (1993) Gen Pharmacol , vol.24 , pp. 1123-1131
    • EI-Tahir, K.E.1    Ashour, M.M.2    AI-Harbi, M.M.3
  • 40
    • 0037699276 scopus 로고    scopus 로고
    • Effect of Nigella sativa on blood level and structure of liver and pancreas in adult male albino rats
    • El-Zawahrawy B, Fatma AI, Zahraa AH (1998) Effect of Nigella sativa on blood level and structure of liver and pancreas in adult male albino rats. AI-Azhar Med J 27: 479-483
    • (1998) AI-Azhar Med , vol.J 27 , pp. 479-483
    • El-Zawahrawy, B.1    Fatma, A.I.2    Zahraa, A.H.3
  • 41
    • 0035080283 scopus 로고    scopus 로고
    • Hematological studies on black cumin oil from the seeds of Nigella sativa L
    • Enomoto S, Asano R, Iwahori Y, et al. (2001) Hematological studies on black cumin oil from the seeds of Nigella sativa L. Biol Pharm Bull 24: 307-310
    • (2001) Biol Pharm Bull , vol.24 , pp. 307-310
    • Enomoto, S.1    Asano, R.2    Iwahori, Y.3
  • 42
    • 0033120349 scopus 로고    scopus 로고
    • High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.)
    • Ghosheh OA, Houdi AA, Crooks PA (1999) High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.). J Pharm Biomed Anal 19(5): 757-62
    • (1999) J Pharm Biomed Anal , vol.19 , Issue.5 , pp. 757-762
    • Ghosheh, O.A.1    Houdi, A.A.2    Crooks, P.A.3
  • 44
    • 2342626583 scopus 로고    scopus 로고
    • Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug
    • Hajhashemi V, Ghannadi A, Jafarabadi H (2004) Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. Phytother Res 18(3): 195-199
    • (2004) Phytother Res , vol.18 , Issue.3 , pp. 195-199
    • Hajhashemi, V.1    Ghannadi, A.2    Jafarabadi, H.3
  • 45
    • 0025914525 scopus 로고
    • Studies on the antimicrobial activity of Nigella sativa seed (black cumin)
    • Hanafy MS, Hatem ME (1991) Studies on the antimicrobial activity of Nigella sativa seed (black cumin). J Ethnopharmacol 34(2-3): 275-278
    • (1991) J Ethnopharmacol , vol.34 , Issue.2-3 , pp. 275-278
    • Hanafy, M.S.1    Hatem, M.E.2
  • 46
    • 0029100394 scopus 로고
    • Nigella sativa: Effect on human lymphocytes and polymorphonuclear leukocyte phagocytic activity
    • Haq A, Abdullatif M, Lobo PI, et al. (1995) Nigella sativa: effect on human lymphocytes and polymorphonuclear leukocyte phagocytic activity. Immunopharmacol 30: 147-155
    • (1995) Immunopharmacol , vol.30 , pp. 147-155
    • Haq, A.1    Abdullatif, M.2    Lobo, P.I.3
  • 47
    • 0033012875 scopus 로고    scopus 로고
    • Immunomodulatory effect of Nigella sativa proteins by ion exchange chromatography
    • Haq A, Lobo P, AI-Tufail M, et al. (1999) Immunomodulatory effect of Nigella sativa proteins by ion exchange chromatography. Int J Immunopharmacol 21: 283-295
    • (1999) Int J Immunopharmacol , vol.21 , pp. 283-295
    • Haq, A.1    Lobo, P.2    AI-Tufail, M.3
  • 48
    • 0035719313 scopus 로고    scopus 로고
    • Effect of Nigella sativa (Black seed) and thymoquinone on blood glucose in albino rats
    • Hawsawi ZA, Ali BA, Bamosa AO (2001) Effect of Nigella sativa (Black seed) and thymoquinone on blood glucose in albino rats. Ann Saudi Med 21(3-4): 242-244
    • (2001) Ann Saudi Med , vol.21 , Issue.3-4 , pp. 242-244
    • Hawsawi, Z.A.1    Ali, B.A.2    Bamosa, A.O.3
  • 49
    • 0028852880 scopus 로고
    • Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation
    • Houghton PJ, Zarka R, de las Heras B, et al. (1995) Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med 61: 33-36
    • (1995) Planta Med , vol.61 , pp. 33-36
    • Houghton, P.J.1    Zarka, R.2    de las Heras, B.3
  • 50
    • 0027379097 scopus 로고
    • CNS and analgesic studies on Nigella sativa
    • Khanna T, Zaidi FA, Dandiya PC (1993) CNS and analgesic studies on Nigella sativa. Fitoterapia 64: 407-410
    • (1993) Fitoterapia , vol.64 , pp. 407-410
    • Khanna, T.1    Zaidi, F.A.2    Dandiya, P.C.3
  • 51
    • 0035098984 scopus 로고    scopus 로고
    • Extraction, isolation and characterization of antitumor principle, alpha-hederin, from the seeds of Nigella sativa
    • Kumara SS, Huât BT (2001) Extraction, isolation and characterization of antitumor principle, alpha-hederin, from the seeds of Nigella sativa. Planta Med 67: 29-32
    • (2001) Planta Med , vol.67 , pp. 29-32
    • Kumara, S.S.1    Huât, B.T.2
  • 53
    • 0036136661 scopus 로고    scopus 로고
    • The effects of Nigella sativa oil against the liver damage induced by Schistosoma mansonii mice
    • Mahmoud MR, EI-Abhar HS, Saieh S (2002) The effects of Nigella sativa oil against the liver damage induced by Schistosoma mansonii mice. J Ethnopharmacol 79: 1-11
    • (2002) J Ethnopharmacol , vol.79 , pp. 1-11
    • Mahmoud, M.R.1    EI-Abhar, H.S.2    Saieh, S.3
  • 54
    • 33846906435 scopus 로고
    • In Salah et le Tidikelt oriental, Etude historique, géographique et médicale
    • Maire A, Savelli A (1955) In Salah et le Tidikelt oriental, Etude historique, géographique et médicale. Arch Inst Pasteur Alger 33(4): 367-432
    • (1955) Arch Inst Pasteur Alger , vol.33 , Issue.4 , pp. 367-432
    • Maire, A.1    Savelli, A.2
  • 55
    • 0014859993 scopus 로고
    • Studies on the antihistaminic effects of thymoquinone, thymohydroquinone and quercitin
    • Marozzi FJ, Koclalski AB, Malone MH (1970) Studies on the antihistaminic effects of thymoquinone, thymohydroquinone and quercitin. Drug Res 20: 1574-1577
    • (1970) Drug Res , vol.20 , pp. 1574-1577
    • Marozzi, F.J.1    Koclalski, A.B.2    Malone, M.H.3
  • 56
    • 0035752777 scopus 로고    scopus 로고
    • Effect of Nigella sativa on glucose concentration, lipid peroxidation, anti-oxidant defence system and liver damage in experimentally-induced diabetic rabbits
    • Meral I, Yener Z, Kahraman T, et al. (2001) Effect of Nigella sativa on glucose concentration, lipid peroxidation, anti-oxidant defence system and liver damage in experimentally-induced diabetic rabbits. J Vet Med A 48: 593-599
    • (2001) J Vet Med A , vol.48 , pp. 593-599
    • Meral, I.1    Yener, Z.2    Kahraman, T.3
  • 57
    • 0030815142 scopus 로고    scopus 로고
    • Flavonoid triglycerides from seeds of Nigella sativa
    • Merfort I, Wray V, Barakat HH, et al. (1997) Flavonoid triglycerides from seeds of Nigella sativa. Phytochemistry 46: 359-363
    • (1997) Phytochemistry , vol.46 , pp. 359-363
    • Merfort, I.1    Wray, V.2    Barakat, H.H.3
  • 58
    • 0033945636 scopus 로고    scopus 로고
    • Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria
    • Morsi NM (2000) Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria. Acta Microbiol Pol 49: 63-74
    • (2000) Acta Microbiol Pol , vol.49 , pp. 63-74
    • Morsi, N.M.1
  • 59
    • 0030778952 scopus 로고    scopus 로고
    • A study of the anti-inflammatory activity of Nigella sativa L. and thymoquinone in rats
    • Mutabagani A, EI-Mahdi SM (1997) A study of the anti-inflammatory activity of Nigella sativa L. and thymoquinone in rats. Saudi Pharmacol J 5: 110-113
    • (1997) Saudi Pharmacol J , vol.5 , pp. 110-113
    • Mutabagani, A.1    EI-Mahdi, S.M.2
  • 60
    • 33751319611 scopus 로고
    • Indian Materia Medica
    • Bombay, India, p
    • Nadkarni AK (1976) Indian Materia Medica. Popular Parkishan: Bombay, India, p 854
    • (1976) Popular Parkishan , pp. 854
    • Nadkarni, A.K.1
  • 61
    • 0033065662 scopus 로고    scopus 로고
    • Thymoquinone protects against carbon tetrachloride hepatotoxicity in mice via an antioxidant mechanism
    • Nagi MM, Alam K, Badary OA (1999) Thymoquinone protects against carbon tetrachloride hepatotoxicity in mice via an antioxidant mechanism. Biochem Mol Biol Int 47: 143-159
    • (1999) Biochem Mol Biol Int , vol.47 , pp. 143-159
    • Nagi, M.M.1    Alam, K.2    Badary, O.A.3
  • 62
    • 0025956720 scopus 로고
    • Modulatory effects of Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in mice
    • Nair SC, Salomi MJ, Panikkar B, et al. (1991) Modulatory effects of Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in mice. J Ethnopharmacol 31: 16-20
    • (1991) J Ethnopharmacol , vol.31 , pp. 16-20
    • Nair, S.C.1    Salomi, M.J.2    Panikkar, B.3
  • 63
    • 1542588292 scopus 로고
    • Taghit (Sahara oranais) : Étude historique, géographique et médicale
    • Passager P, Barbançon S (1956) Taghit (Sahara oranais) : étude historique, géographique et médicale. Arch Inst Pasteur Alger 34(3): 404-475
    • (1956) Arch Inst Pasteur Alger , vol.34 , Issue.3 , pp. 404-475
    • Passager, P.1    Barbançon, S.2
  • 64
    • 33846904935 scopus 로고
    • El Golea (Sahara algérois) : Étude historique, géographique et médicale
    • Passager P, Dorey R (1958) El Golea (Sahara algérois) : étude historique, géographique et médicale. Arch Inst Pasteur Alger 36(1): 74-152
    • (1958) Arch Inst Pasteur Alger , vol.36 , Issue.1 , pp. 74-152
    • Passager, P.1    Dorey, R.2
  • 65
    • 33846929810 scopus 로고
    • Le Gourara : Étude historique, géographique et médicale
    • Reboul E (1953) Le Gourara : étude historique, géographique et médicale. Arch Inst Pasteur Alger 31(2): 164-246
    • (1953) Arch Inst Pasteur Alger , vol.31 , Issue.2 , pp. 164-246
    • Reboul, E.1
  • 66
    • 0025774015 scopus 로고
    • Anti-tumor principles from Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis in mice
    • Salomi NJ, Nair SC, Jayawardhanan KK, et al. (1992) Anti-tumor principles from Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis in mice. Nutr Cancer 16: 67-72
    • (1992) Nutr Cancer , vol.16 , pp. 67-72
    • Salomi, N.J.1    Nair, S.C.2    Jayawardhanan, K.K.3
  • 67
    • 0018870971 scopus 로고
    • Traditional medicine in health care
    • Sayed MD (1980) Traditional medicine in health care. J Ethnopharmacol 2: 19-22
    • (1980) J Ethnopharmacol , vol.2 , pp. 19-22
    • Sayed, M.D.1
  • 70
    • 0034108281 scopus 로고    scopus 로고
    • Cytotoxic and immunopotentiating effects of ethanolic extract of Nigella sativa L. seeds
    • Swamy SMK, Tan BKH (2000) Cytotoxic and immunopotentiating effects of ethanolic extract of Nigella sativa L. seeds. J Ethnopharmacol 70: 1-7
    • (2000) J Ethnopharmacol , vol.70 , pp. 1-7
    • Swamy, S.M.K.1    Tan, B.K.H.2
  • 71
    • 0035098984 scopus 로고    scopus 로고
    • Extraction, isolation and characterisation of antitumor principle, α-hederin, from the seeds of Nigella sativa
    • Swamy SMK, Benny TKH (2001) Extraction, isolation and characterisation of antitumor principle, α-hederin, from the seeds of Nigella sativa. Planta Med 67: 29-32
    • (2001) Planta Med , vol.67 , pp. 29-32
    • Swamy, S.M.K.1    Benny, T.K.H.2
  • 72
    • 0037357643 scopus 로고    scopus 로고
    • Intracellular glutathione depletion and reactive oxygen species generation are important in alpha-hederin-induced apoptosis of P388 cells
    • Swamy SM, Huat BT (2003) Intracellular glutathione depletion and reactive oxygen species generation are important in alpha-hederin-induced apoptosis of P388 cells. Mol Cell Biochem 245(1-2): 127-39
    • (2003) Mol Cell Biochem , vol.245 , Issue.1-2 , pp. 127-139
    • Swamy, S.M.1    Huat, B.T.2
  • 74
    • 0034186616 scopus 로고    scopus 로고
    • Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat
    • Zaoui A, Cherrah Y, Lacaille-Dubois MA, et al. (2000) Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat. Thérapie 55: 379-382
    • (2000) Thérapie , vol.55 , pp. 379-382
    • Zaoui, A.1    Cherrah, Y.2    Lacaille-Dubois, M.A.3
  • 75
    • 0036136675 scopus 로고    scopus 로고
    • Effects of Nigella sativa fixed oil on blood homeostasis in rat
    • Zaoui A, Cherrah Y, Alaoui K, et al. (2002) Effects of Nigella sativa fixed oil on blood homeostasis in rat. J Ethnopharmacol 79: 23-26
    • (2002) J Ethnopharmacol , vol.79 , pp. 23-26
    • Zaoui, A.1    Cherrah, Y.2    Alaoui, K.3
  • 76
    • 0036184031 scopus 로고    scopus 로고
    • Acute and chronic toxicity of Nigella sativa fixed oil
    • Zaoui A, Cherrah Y, Mahassine N, et al. (2002) Acute and chronic toxicity of Nigella sativa fixed oil. Phytomedicine 9: 69-74
    • (2002) Phytomedicine , vol.9 , pp. 69-74
    • Zaoui, A.1    Cherrah, Y.2    Mahassine, N.3
  • 77
    • 33846932487 scopus 로고    scopus 로고
    • http://www.uni-graz.at/~Ekatzer/engl/Nige_sat.html


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.