Immunization with non-replicating E. coli minicells delivering both protein antigen and DNA protects mice from lethal challenge with lymphocytic choriomeningitis virus

Vaccine

Volumn 25, Issue 12, 2007, Pages 2279-2287

  Giacalone, Matthew J ^a,b   Zapata, Juan C ^c   Berkley, Neil L ^a   Sabbadini, Roger A ^a,b   Chu, Yen Lin ^b   Salvato, Maria S ^c   McGuire, Kathleen L ^a,b  

^a VaxiionTherapeutics   (United States)

^b SAN DIEGO STATE UNIVERSITY   (United States)

^c INSTITUTE OF HUMAN VIROLOGY   (United States)

Author keywords

Immune response; LCMV; Minicells; Mucosal delivery; Vaccine

Indexed keywords

BACTERIAL VACCINE; DNA VACCINE; VIRUS PROTEIN; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CELL; BACTERIAL STRAIN; CELL STRAIN COS7; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG DELIVERY SYSTEM; ESCHERICHIA COLI; FEMALE; IMMUNIZATION; INFECTION PREVENTION; LETHALITY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA VIRUS INFECTION;

ADMINISTRATION, INTRANASAL; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; DRUG DELIVERY SYSTEMS; ESCHERICHIA COLI; IMMUNIZATION; INJECTIONS, INTRAMUSCULAR; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; NUCLEOPROTEINS; VACCINES, DNA; VERO CELLS; VIRAL VACCINES;

EID: 33846885685     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.11.069     Document Type: Article

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