메뉴 건너뛰기




Volumn 102, Issue 2, 2007, Pages 628-633

Effects of forskolin on inotropic performance and phospholamban phosphorylation in exercise-trained hypertensive myocardium

Author keywords

Diastole; Heart; Hypertrophy; Proteins; Spontaneously hypertensive rat

Indexed keywords

FORSKOLIN; PHOSPHOLAMBAN;

EID: 33846879598     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00449.2006     Document Type: Article
Times cited : (12)

References (52)
  • 1
    • 0029881890 scopus 로고    scopus 로고
    • G-proteins and adenylyl cyclase signaling in hypertension
    • Anand-Srivastava MB. G-proteins and adenylyl cyclase signaling in hypertension. Mol Cell Biochem 157: 163-170, 1996.
    • (1996) Mol Cell Biochem , vol.157 , pp. 163-170
    • Anand-Srivastava, M.B.1
  • 2
    • 0029066798 scopus 로고
    • Modulation of left and right ventricular β-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure
    • Atkins FL, Bing O, Dimauro PG, Conrad CH, Robinson KG, Brooks WW. Modulation of left and right ventricular β-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure. Hypertension 26: 78-82, 1995.
    • (1995) Hypertension , vol.26 , pp. 78-82
    • Atkins, F.L.1    Bing, O.2    Dimauro, P.G.3    Conrad, C.H.4    Robinson, K.G.5    Brooks, W.W.6
  • 3
    • 0030614353 scopus 로고    scopus 로고
    • Beta-adrenoceptors in the hearts of diabetic-hypertensive rats: Radioligand binding and functional experiments
    • Beenan OH, Batink HD, Pfaffendorf M, van Zwieten PA. Beta-adrenoceptors in the hearts of diabetic-hypertensive rats: radioligand binding and functional experiments. Blood Press 6: 44-51, 1997.
    • (1997) Blood Press , vol.6 , pp. 44-51
    • Beenan, O.H.1    Batink, H.D.2    Pfaffendorf, M.3    van Zwieten, P.A.4
  • 7
    • 0028283259 scopus 로고
    • Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure: Marked upregulation of genes encoding extracellular matrix components
    • Boluyt MO, O'Neill L, Meredith AL, Bing OHL, Brooks WW, Conrad CH, Crow MT, Lakatta EG. Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure: marked upregulation of genes encoding extracellular matrix components. Circ Res 75: 23-32, 1994.
    • (1994) Circ Res , vol.75 , pp. 23-32
    • Boluyt, M.O.1    O'Neill, L.2    Meredith, A.L.3    Bing, O.H.L.4    Brooks, W.W.5    Conrad, C.H.6    Crow, M.T.7    Lakatta, E.G.8
  • 8
    • 0022337115 scopus 로고
    • Forskolin: Effects on cyclic AMP and contractile function in the isolated rat and guinea pig heart
    • Buschmans E, Hearse DJ, Manning AS. Forskolin: effects on cyclic AMP and contractile function in the isolated rat and guinea pig heart. Can J Cardiol 1: 385-394, 1985.
    • (1985) Can J Cardiol , vol.1 , pp. 385-394
    • Buschmans, E.1    Hearse, D.J.2    Manning, A.S.3
  • 10
    • 0030798818 scopus 로고    scopus 로고
    • Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase
    • Choi DJ, Koch WJ, Hunter JJ, Rockman HA. Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase. J Biol Chem 272: 17223-17229, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 17223-17229
    • Choi, D.J.1    Koch, W.J.2    Hunter, J.J.3    Rockman, H.A.4
  • 11
    • 0014135269 scopus 로고
    • Effect of chronic exercise on myocardial function
    • Crews J, Aldinger EE. Effect of chronic exercise on myocardial function. Am Heart J 74: 536-542, 1967.
    • (1967) Am Heart J , vol.74 , pp. 536-542
    • Crews, J.1    Aldinger, E.E.2
  • 12
    • 0022540455 scopus 로고
    • Dobutamine-induced cardiac adaptations: Comparison with exercise-trained and sedentary rats
    • Davidson WR, Banerjee SP, Liang CS. Dobutamine-induced cardiac adaptations: comparison with exercise-trained and sedentary rats. Am J Physiol Heart Circ Physiol 250: H725-H730, 1986.
    • (1986) Am J Physiol Heart Circ Physiol , vol.250
    • Davidson, W.R.1    Banerjee, S.P.2    Liang, C.S.3
  • 13
    • 0030832040 scopus 로고    scopus 로고
    • Interactions of forskolin and ATP with the cytosolic domains of mammalian adenylyl cyclase
    • Dessauer CW, Scully TT, Gilman AG. Interactions of forskolin and ATP with the cytosolic domains of mammalian adenylyl cyclase. J Biol Chem 272: 22272-22277, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 22272-22277
    • Dessauer, C.W.1    Scully, T.T.2    Gilman, A.G.3
  • 15
    • 0032127809 scopus 로고    scopus 로고
    • Rat models of hypertension, cardiac hypertrophy and failure
    • Doggrel SA, Brown L. Rat models of hypertension, cardiac hypertrophy and failure. Cardiovasc Res 39: 89-105, 1998.
    • (1998) Cardiovasc Res , vol.39 , pp. 89-105
    • Doggrel, S.A.1    Brown, L.2
  • 16
    • 0017189204 scopus 로고
    • Effect of exercise training on adenylyl cyclase and phosphodiesterase in skeletal muscle, heart, and liver
    • Dohm GL, Pennington SN, Barakat H. Effect of exercise training on adenylyl cyclase and phosphodiesterase in skeletal muscle, heart, and liver. Biochem Med 16: 138-142, 1976.
    • (1976) Biochem Med , vol.16 , pp. 138-142
    • Dohm, G.L.1    Pennington, S.N.2    Barakat, H.3
  • 17
    • 0015890583 scopus 로고
    • Sympathectomy and pharmacological blockade in trained rats
    • Ekblom B, Kilbom A, Soltysiak J. Sympathectomy and pharmacological blockade in trained rats. Acta Physiol Scand 89: 283-285, 1973.
    • (1973) Acta Physiol Scand , vol.89 , pp. 283-285
    • Ekblom, B.1    Kilbom, A.2    Soltysiak, J.3
  • 18
    • 0023192489 scopus 로고
    • Effects of forskolin on contractile responses and protein phosphorylation in the isolated perfused rat heart
    • England PJ, Shahid M. Effects of forskolin on contractile responses and protein phosphorylation in the isolated perfused rat heart. Biochem J 246: 687-695, 1987.
    • (1987) Biochem J , vol.246 , pp. 687-695
    • England, P.J.1    Shahid, M.2
  • 19
    • 0019811396 scopus 로고
    • Effect of an exercise run to exhaustion on cAMP in the rat heart
    • Goldfarb AH, Kendrick ZV. Effect of an exercise run to exhaustion on cAMP in the rat heart. J Appl Physiol 51: 1539-1542, 1981.
    • (1981) J Appl Physiol , vol.51 , pp. 1539-1542
    • Goldfarb, A.H.1    Kendrick, Z.V.2
  • 20
    • 0022549828 scopus 로고
    • Intensity and duration effects of exercise on heart cAMP, phosphorylase, and glycogen
    • Goldfarb AH, Bruno JF, Buckenmeyer PJ. Intensity and duration effects of exercise on heart cAMP, phosphorylase, and glycogen. J Appl Physiol 60: 1268-1273, 1986.
    • (1986) J Appl Physiol , vol.60 , pp. 1268-1273
    • Goldfarb, A.H.1    Bruno, J.F.2    Buckenmeyer, P.J.3
  • 21
    • 0025223081 scopus 로고
    • Turning off the signal: Densensitization of beta-adrenergic function
    • Hausdorff WP, Caron MG, Lefkowitz RJ. Turning off the signal: densensitization of beta-adrenergic function. FASEB J 4: 2881-2890, 1990.
    • (1990) FASEB J , vol.4 , pp. 2881-2890
    • Hausdorff, W.P.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 22
    • 0022499714 scopus 로고
    • Forskolin and myocardial function in the normal, ischemic and reperfused rat heart
    • Hearse DJ, Zucchi R, Buschmans E, Manning AS. Forskolin and myocardial function in the normal, ischemic and reperfused rat heart. Can J Cardiol 2: 303-312, 1986.
    • (1986) Can J Cardiol , vol.2 , pp. 303-312
    • Hearse, D.J.1    Zucchi, R.2    Buschmans, E.3    Manning, A.S.4
  • 26
    • 0011914967 scopus 로고
    • Beta-adrenergic receptor response coupling in hypertrophied hearts
    • Kumano K, Upsher ME, Khairallah PA. Beta-adrenergic receptor response coupling in hypertrophied hearts. Hypertension 5: I175-I183, 1983.
    • (1983) Hypertension , vol.5
    • Kumano, K.1    Upsher, M.E.2    Khairallah, P.A.3
  • 28
    • 0027287547 scopus 로고
    • G-proteins in experimental hypertension: A study of spontaneously hypertensive rat myocardial and renal cortical plasma membranes
    • McLellan AR, Milligan G, Houslay MD, Connell JM. G-proteins in experimental hypertension: a study of spontaneously hypertensive rat myocardial and renal cortical plasma membranes. J Hypertens 11: 365-372, 1993.
    • (1993) J Hypertens , vol.11 , pp. 365-372
    • McLellan, A.R.1    Milligan, G.2    Houslay, M.D.3    Connell, J.M.4
  • 29
    • 0018254830 scopus 로고
    • Increased contractile potential of papillary muscles from exercise-trained rat hearts
    • Mole PA. Increased contractile potential of papillary muscles from exercise-trained rat hearts. Am J Physiol Heart Circ Physiol 234: H421-H425, 1978.
    • (1978) Am J Physiol Heart Circ Physiol , vol.234
    • Mole, P.A.1
  • 30
    • 0019976872 scopus 로고
    • Effect of training on β-adrenergic receptor number in rat heart
    • Moore RL, Riedy M, Gollnick PD. Effect of training on β-adrenergic receptor number in rat heart. J Appl Physiol 52: 1133-1137, 1982.
    • (1982) J Appl Physiol , vol.52 , pp. 1133-1137
    • Moore, R.L.1    Riedy, M.2    Gollnick, P.D.3
  • 31
    • 0027216085 scopus 로고
    • Correlation of myosin heavy chain expression in the rat with cAMP in different models of hypertension-induced cardiac hypertrophy
    • Morano I, Adler K, Weismann K, Knorr A, Erdmann E, Bohm M. Correlation of myosin heavy chain expression in the rat with cAMP in different models of hypertension-induced cardiac hypertrophy. J Mol Cell Cardiol 25: 387-394, 1993.
    • (1993) J Mol Cell Cardiol , vol.25 , pp. 387-394
    • Morano, I.1    Adler, K.2    Weismann, K.3    Knorr, A.4    Erdmann, E.5    Bohm, M.6
  • 32
    • 0027415291 scopus 로고
    • Cardiac beta-adrenoceptors, G-proteins and adenylate cyclase regulation during myocardial hypertrophy
    • Nieto JL, Diaz-Laviada I, Guillen A, Garcia-Barreno P, Haro A. Cardiac beta-adrenoceptors, G-proteins and adenylate cyclase regulation during myocardial hypertrophy. Cell Signal 5: 169-179, 1993.
    • (1993) Cell Signal , vol.5 , pp. 169-179
    • Nieto, J.L.1    Diaz-Laviada, I.2    Guillen, A.3    Garcia-Barreno, P.4    Haro, A.5
  • 33
    • 0029947573 scopus 로고    scopus 로고
    • Adenylyl cyclase system is affected differently by endurance physical training in heart and adipose tissue
    • Nieto JL, Laviada ID, Guillen A, Haro A. Adenylyl cyclase system is affected differently by endurance physical training in heart and adipose tissue. Biochem Pharmacol 51: 1321-1329, 1996.
    • (1996) Biochem Pharmacol , vol.51 , pp. 1321-1329
    • Nieto, J.L.1    Laviada, I.D.2    Guillen, A.3    Haro, A.4
  • 34
    • 0019520264 scopus 로고
    • Endurance training in the rat. I. Myocardial mechanics and biochemistry
    • Nutter DO, Priest RE, Fuller EO. Endurance training in the rat. I. Myocardial mechanics and biochemistry. J Appl Physiol 51: 934-940, 1981.
    • (1981) J Appl Physiol , vol.51 , pp. 934-940
    • Nutter, D.O.1    Priest, R.E.2    Fuller, E.O.3
  • 35
    • 0019391826 scopus 로고
    • Exercise-induced increases in myocardial adenosine 3′,5′-cyclic monophosphate and phosphodiesterase activity
    • Palmer WK, Studney TA, Doukas S. Exercise-induced increases in myocardial adenosine 3′,5′-cyclic monophosphate and phosphodiesterase activity. Biochim Biophys Acta 672: 114-122, 1981.
    • (1981) Biochim Biophys Acta , vol.672 , pp. 114-122
    • Palmer, W.K.1    Studney, T.A.2    Doukas, S.3
  • 36
    • 0024264022 scopus 로고
    • Effect of exercise on cardiac cyclic AMP
    • Palmer WK. Effect of exercise on cardiac cyclic AMP. Med Sci Sports Exerc 20: 525-530, 1988.
    • (1988) Med Sci Sports Exerc , vol.20 , pp. 525-530
    • Palmer, W.K.1
  • 37
    • 0017686605 scopus 로고
    • Response of immunosympathectomized rats in training
    • Paynter DE, Tipton CM, Tcheng T. Response of immunosympathectomized rats in training. J Appl Physiol 42: 935-940, 1977.
    • (1977) J Appl Physiol , vol.42 , pp. 935-940
    • Paynter, D.E.1    Tipton, C.M.2    Tcheng, T.3
  • 38
    • 0032127132 scopus 로고    scopus 로고
    • Lessons from rat models of hypertension: From Goldblatt to genetic engineering
    • Pinto YM, Paul M, Ganten D. Lessons from rat models of hypertension: from Goldblatt to genetic engineering. Cardiovasc Res 39: 77-88, 1998.
    • (1998) Cardiovasc Res , vol.39 , pp. 77-88
    • Pinto, Y.M.1    Paul, M.2    Ganten, D.3
  • 39
    • 0025904872 scopus 로고
    • β-Adrenergic adenylate cyclase system adaptation to physical training in rat ventricular tissue
    • Plourde G, Rousseau-Migneron S, Nadeau A. β-Adrenergic adenylate cyclase system adaptation to physical training in rat ventricular tissue. J Appl Physiol 70: 1633-1638, 1991.
    • (1991) J Appl Physiol , vol.70 , pp. 1633-1638
    • Plourde, G.1    Rousseau-Migneron, S.2    Nadeau, A.3
  • 42
    • 0031933301 scopus 로고    scopus 로고
    • Alterations in myocardial signal transduction due to aging and chronic dynamic exercise
    • Roth DA, White CD, Podolin DA, Mazzeo RS. Alterations in myocardial signal transduction due to aging and chronic dynamic exercise. J Appl Physiol 84: 177-184, 1998.
    • (1998) J Appl Physiol , vol.84 , pp. 177-184
    • Roth, D.A.1    White, C.D.2    Podolin, D.A.3    Mazzeo, R.S.4
  • 43
    • 0027939626 scopus 로고
    • Influence of exercise training on myocardial beta-adrenergic signal transduction: Differential regulation with age
    • Scarpace PJ, Shu Y, Tumer N. Influence of exercise training on myocardial beta-adrenergic signal transduction: differential regulation with age. J Appl Physiol 77: 737-741, 1994.
    • (1994) J Appl Physiol , vol.77 , pp. 737-741
    • Scarpace, P.J.1    Shu, Y.2    Tumer, N.3
  • 44
    • 2342652901 scopus 로고
    • Forskolin: Unique diterpene activator of adenylate cyclase in membranes and in intact cells
    • Seamon KB, Padgett W, Daly JW. Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc Natl Acad Sci USA 78: 3363-3367, 1981.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 3363-3367
    • Seamon, K.B.1    Padgett, W.2    Daly, J.W.3
  • 45
    • 0021358238 scopus 로고
    • Forskolin, a new positive inotropic agent and its influence on myocardial electrogenic cation movements
    • Spah F. Forskolin, a new positive inotropic agent and its influence on myocardial electrogenic cation movements. J Cardiovasc Pharmacol 6: 99-106, 1984.
    • (1984) J Cardiovasc Pharmacol , vol.6 , pp. 99-106
    • Spah, F.1
  • 46
    • 0026566002 scopus 로고
    • Exercise training improves left ventricular contractile response to β-adrenergic agonist
    • Spina RJ, Ogawa T, Coggan AR, Holloszy JO, Ehsani AA. Exercise training improves left ventricular contractile response to β-adrenergic agonist. J Appl Physiol 72: 307-311, 1992.
    • (1992) J Appl Physiol , vol.72 , pp. 307-311
    • Spina, R.J.1    Ogawa, T.2    Coggan, A.R.3    Holloszy, J.O.4    Ehsani, A.A.5
  • 47
    • 77957010982 scopus 로고
    • Citrate synthase
    • Srere PA. Citrate synthase. Methods Enzymol 13: 3-11, 1969.
    • (1969) Methods Enzymol , vol.13 , pp. 3-11
    • Srere, P.A.1
  • 48
    • 0035029169 scopus 로고    scopus 로고
    • Compartmentation of G protein-coupled signaling pathways in cardiac myocytes
    • Steinberg SF, Brunton LL. Compartmentation of G protein-coupled signaling pathways in cardiac myocytes. Annu Rev Pharmacol Toxicol 41: 751-773, 2001.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 751-773
    • Steinberg, S.F.1    Brunton, L.L.2
  • 49
    • 0021970275 scopus 로고
    • The influence of endurance training on mechanical catecholamine responsiveness, β-adrenoceptor density and myosin isozyme pattern of rat ventricular myocardium
    • Takeda N, Dominiak D, Turek D, Rupp H, Jacob R. The influence of endurance training on mechanical catecholamine responsiveness, β-adrenoceptor density and myosin isozyme pattern of rat ventricular myocardium. Basic Res Cardiol 80: 88-99, 1985.
    • (1985) Basic Res Cardiol , vol.80 , pp. 88-99
    • Takeda, N.1    Dominiak, D.2    Turek, D.3    Rupp, H.4    Jacob, R.5
  • 51
    • 0034677823 scopus 로고    scopus 로고
    • Beta-adrenergic receptor signaling: An acute compensatory adjustment-inappropriate for the chronic stress of heart failure? Insights from Gs alpha overexpression and other genetically engineered animal models
    • Vatner SF, Vatner DE, Homcy CJ. Beta-adrenergic receptor signaling: an acute compensatory adjustment-inappropriate for the chronic stress of heart failure? Insights from Gs alpha overexpression and other genetically engineered animal models. Circ Res 86: 502-506, 2000.
    • (2000) Circ Res , vol.86 , pp. 502-506
    • Vatner, S.F.1    Vatner, D.E.2    Homcy, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.