Adenylyl cyclase system is affected differently by endurance physical training in heart and adipose tissue

Biochemical Pharmacology

Volumn 51, Issue 10, 1996, Pages 1321-1329

  Nieto, José L ^a   Laviada, Inés D ^a   Guillén, Alberto ^a   Haro, Amador ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

adenylyl cyclase; exercise; G proteins; adrenoceptors

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CARBACHOL; CYANOPINDOLOL I 125; CYCLOHEXYLADENOSINE; FLUORIDE; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; MANGANESE; MEMBRANE ENZYME; PROSTAGLANDIN E2; PROTEIN SUBUNIT; RADIOLIGAND; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ADAPTATION; ADENOSINE DIPHOSPHATE RIBOSYLATION; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDURANCE; ENZYME ACTIVITY; EXERCISE; HEART LEFT VENTRICLE; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; TRAINING; TREADMILL EXERCISE;

EID: 0029947573     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00040-8     Document Type: Article

References (38)

1. Portmans JR. Ed. Principles of Exercise Biochemistry, 2nd Edition, Karger, Basel, 1993.
2. Moore RL and Horzick DH, Cellular adaptations of the myocardium to chronic exercise. Prog Cardiovasc Dis 37: 371-396, 1995.
3. Coppack SW, Jensen MD and Miles JM, In vivo regulation of lipolysis in humans. J Lipid Res 35: 177-193,
4. Svedenhag J, Influence of physical training on plasma catecholamine concentrations at rest and during exercise. Acta Physiol Scand 125: 33-37, 1985.
5. Taussig R and Gilman AG, Mammalian membrane-bound adenylyl cyclases. J Biol Chem 270: 1-4, 1995.
6. Williams RS and Bishop T, Enhanced receptor-cyclase coupling and augmented catecholamine-stimulated lipolysis in exercising rats. Am J Physiol 243: E345-E351, 1982.
7. Izawa T, Komabayashi T, Mochizuki T, Suda K and Tsuboi M, Enhanced coupling of adenylate cyclase to lipolysis in permeabilized adipocytes from trained rats. J Appl Physiol 71: 23-29, 1991.
8. Wahrenberg H, Bolinder J and Arner P, Adrenergic regulation of lipolysis in human fat cells during exercise. Eur J Clin Invest 21: 534-541, 1991.
9. 2-adrenoceptor expression in fat cells. J Clin Invest 90: 2175-2186, 1992.
10. Belsham GJ, Denton RM and Tanner MJA, Use of a novel rapid preparation of fat-cell plasma membranes employing Percoll to investigate the effects of insulin and adrenaline on membrane protein phosphorylation within intact fat-cells. Biochem J 192: 457-467, 1980.
11. Nieto JL, Díaz-Laviada I, Guillén A, García-Barreno P and Haro A, Cardiac β-adrenoceptors, G-proteins and adenylate cyclase regulation during myocardial hypertrophy. Cell Signalling 5: 169-179, 1993.
12. Scatchard G, The attraction of proteins for small molecules and ions. Ann NY Acad Sci 51: 660-672, 1949.
13. Díaz-Laviada I, Larrodera P, Nieto JL, Cornet ME, Díaz-Meco MT, Sánchez MJ, Guddal PH, Johansen T, Haro A and Moscat J, Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzes hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C. J Biol Chem 266: 1170-1176, 1991.
14. Guillén A, Jallon J-M, Fehrentz J-A, Pantaloni C, Bockaert J and Homburger V, A Go-like protein in Drosophila melonogaster and its expression in memory mutants. EMBO J 9: 1449-1455, 1990.
15. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ, Protein measurement with Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
16. Bugaisky L and Zak R, Biological mechanisms of hypertrophy. In: The Heart and Cardiovascular System (Eds. Fozzard H, Haber E, Katz A, Jennings R and Morgan HE), pp. 1491-1506. Raven Press, New York, 1986.
17. Sylvestre-Gervais L, Nadeau A, Nguyen MH, Tancrede G and Rousseau-Migneron S, Effects of physical training on beta-adrenergic receptors in rat myocardial tissue. Cardiovasc Res 16: 530-534, 1982.
18. Scarpace PJ, Lowenthal DT and Turner N, Influence of exercise and age on myocardial β-adrenergic receptor properties. Exp Gerontol 27: 169-177, 1992.
19. Plourde G, Rousseau-Migneron S and Nadeau A, β-adrenoceptor adenylate cyclase system adaptation to physical training in rat ventricular tissue. J Appl Physiol 70: 1633-1638, 1991.
20. iα expression in senescence. Am J Physiol (Heart Circ Physiol 33) 264: H805-H814, 1993.
21. Moore RL, Riedy M and Gollnick PD, Effect of training on β-adrenergic receptor number in rat heart. J Appl Physiol 52: 1133-1137, 1982.
22. Hammond HK, Ransnas LA and Insel PA, Noncoordinate regulation of cardiac Gs protein on β-adrenergic receptors by a physiological stimulus, chronic dynamic exercise. J Clin Invest 82: 2168-2171, 1988.
23. Döhm GL, Pennington SN and Barakat H, Effect of exercise training on adenylyl cyclase and phosphodiesterase in skeletal muscle, heart and liver. Biochem Med 16: 138-142, 1976.
24. Pappano AJ and Mubagwa K, Actions of muscarinic agents and adenosine on the heart. In: The Heart and Cardiovascular System. 2nd Ed. (Eds. Fozzard HA et al.) pp. 1765-1776, 1992.
25. Feldman AM, Modulation of adrenergic receptors and G-transduction proteins in failing human ventricular myocardium. Circulation 87 [suppl IV]: IV-27-IV-34, 1993.
26. Scarpace PJ, Shu Y and Turner N, Influence of exercise training on myocardial beta-adrenergic signal transduction: differential regulation with age. J Appl Physiol 77: 737-741, 1994.
27. Limbird LE, Hickey AR and Lefkowitz RJ, Unique uncoupling of the frog erythrocyte adenylate cyclase system by manganese. Loss of hormone and guanine nucleotide-sensitive enzyme activities without loss of nucleotide-sensitive, high affinity agonist binding. J Biol Chem 254: 2677-2683, 1979.
28. Hubbard JW, Conway PG, Nordstrom LC, Hartman HB, Lebedinsky Y, O'Malley GJ and Kosley RW, Cardiac adenylate cyclase activity, positive chronotropic and inotropic effects of forskolin analogs with either low, medium or high binding site affinity. J Pharmacol Exp Ther 256: 621-627, 1991.
29. Eschenhagen T, G proteins and the heart. Cell Biol International 17: 723-749, 1993.
30. i3α in adipocytes of hypothyroid rats. Biochem J 270: 765-769, 1990.
31. Green A, Johnson JL and Milligan G, Down-regulation of Gi sub-types by prolonged incubation of adipocytes with an A1 adenosine receptor agonist. J Biol Chem 265: 5206-5210, 1990.
32. Bristow MR, Kantrowitz NE, Ginsburg R and Fowler MB, β-adrenergic function in heart muscle disease and heart failure. J Mol Cell Cardiol 17: 41-52, 1985.
33. Marquetant R, Brehm B and Strasser RH, Chronic β-blockade transregulates inhibitory A1 adenosine and muscarininc M2 receptors of the adenylyl cyclase system. J Mol Cell Cardiol 24: 535-548, 1992.
34. i and adenylate cyclase in HT29 cells. Biochem J 292: 283-288, 1993.
35. Arner P, Adrenergic receptor function in fat cells. Am J Clin Nutr 55: 228 S-236 S, 1992.
36. 3H]GDP release in adipocyte membranes from exercise-trained rats. Jpn J Physiol 36: 1039-1045, 1986.
37. Izawa T, Komabayashi T, Shinoda S, Suda K, Tsuboi M and Koshimizu E, Possible mechanism of regulating adenylate cyclase activity in adipocyte membranes from exercise-trained male rats. Biochem Biophys Res Commun 151: 1262-1268, 1988.
38. Begin-Heick N, α-subunits of G(s) and G(i) in adipocyte plasma membranes of genetically diabetic (db/db) mice. Am J Physiol 263: C121-C129, 1992.