Umckaloabo® in acute bronchitis;Umckaloabo® bei akuter bronchitis

Deutsche Apotheker Zeitung

Volumn 147, Issue 1, 2007, Pages 87-91

  Conrad, Andreas ^a   Schulz, Volker ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 6; UMBELLIFERONE;

BRONCHITIS; HUMAN; IMMUNOMODULATION; SHORT SURVEY;

EID: 33846874127     PISSN: 00119857     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (29)

1. Anonymus: Pelargonium (Umckaloabo) hepatotoxisch? Arznei-telegramm 37, 41-42 (2006).
2. Anonymus: Periodic Safety Update Report on the Tolerability of Pelargonium sidoides Extract EPs 7630. ISO Pharma, Ettlingen 2004.
3. Beil, W.; Kilian, P.: EPs® 7630, an extract from Pelargonium sidoides roots inhibits adherence of Helicobacter pylori to gastric epithelial cells. Phytomedicine Suppl VI 2007; 14: in press
4. Bent, B.; Saint, S.; Vittinghoff, E.; Grady, D.: Antibiotics in acute bronchitis: a metaanalysis. Am. J. Med. 107; 62-67 (1999).
5. Blochin, B.; Haidvogl, M.; Heger, M.: Umckaloabo im Vergleich zu Acetylcystein bei Kindern mit akuter Bronchitis. Der Kassenarzt 49, 46-49 (1999).
6. Butterweck, V.; Derendorf, H.; Gaus, W.; Nahrstedt, A.; Schulz, V.; Unger, M.: Pharmacokinetic herb-drug interactions: Are preventive screenings necessary and appropriate? Planta Med. 70, 784-91 (2004).
7. Chuchalin, A.G.; Berman, B.; Lehmacher, W.: Treatment of acute bronchitis in adults with a Pelargonium sidoides preparation (EPs® 7630): A randomized, double-blind, placebo-controlled trial. Explore 1, 437-445 (2005).
8. Conrad, A.; Hansmann, C.; Engels, I.; Daschner, F. D.; Frank, U.: Extract of Pelargonium sidoides (EPs® 7630) improves phagocytosis, oxidative burst, and intracellular killing of human peripheral blood phagocytes in-vitro. Phytomedicine Suppl. VI 14, in press (2007)
9. Conrad, A.; Jung, I.; Tioua, D.; Lallemand, C.; Carrapatoso, F.; Engels, I.; Daschner, D. D.; Frank, U.: Extract of Pelargonium sidoides (EPs® 7630) inhibits the interactions of group A streptococci and host epithelia in-vitro. Phytomedicine Suppl VI 14, in press (2007).
10. Dietl, R.; Müller, J.: Anwendungsbeobachtung gemäß § 67.6 AMG mit EPs 7630. Biometrischer Bericht. Dr. Willmar Schwabe Arzneimittel GmbH, Karlsruhe 2002.
11. Haidvogl, M.; Heger M, Barti BJ: Treatment of Acute Bronchitis in Children with EPs® 7630-Solution, in Comparison with Acetylcysteine: A Randomized, Multicenter, Double-Blind Double Dummy Active Comparator Controlled Study. in preparation (2007).
12. Haidvogl, M.; Heger, M.: Treatment Effect and Safety of EPs® 7630 solution in Acute Bronchitis in Childhood - Report of a multicentre observational study. Phytomedicine Suppl VI 14, in press (2007).
13. IMS Health: Pharma Scope Analyse. Institut für Medizinische Statistik (IMS), Frankfurt, 2006
14. Kayser, O.; Kolodziej, H.; Kiderlen, A. F.: Immunomodulatory Principles of Pelargonium sidoides. Phytother. Res. X 15, 122-126 (2007).
15. Koch, E.: Untersuchungen zu möglichen hepatotoxischen Effekten von Umckaloabo®. Z. Phytother. Suppl. 27, 25 (2006).
16. Koch, K.; Biber, A.: Treatment of rats with the Pelargonium sidoides extract EPs® 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine Suppl VI 2007; 14: in press
17. Kolodziej, H.; Burmeister, A.; Trun, W.; Radtke, O. A.: Kiderlen, A. F.; Ito, H.; Hatano, T.; Yoshida, T.; Foo, L. Y.: Tannins and related compounds induce nitric oxide synthase and cytokines gene expression in Leishmania major-infected macrophage-like RAW 264.7 cells. Bioorg. & Med. Chem. 13, 6470-6476 (2005).
18. Kolodziej, H.; Kiderlen, A. F.: In vitro Evaluation of Antibacterial and Immunomodulatory Activities of Pelargonium reniforme, Pelargonium sidoides and the related herbal drug preparation EPs® 7630. Phytomedicine Suppl. VI 13, in press (2007).
19. Kolodziej, H.; Schulz, V.: Umckaloabo. Dtsch. Apoth. Ztg. 143, 1303-1312(2003).
20. König, I.: Von der Umckaloabo®-Droge zur Therapie von Atemwegsinfekten. Therapiewoche 19, 1123-26(1995).
21. Matthys, H.; Heger, M.: EPs® 7630 solution - an effective therapeutic option in acute and exacerbating bronchitis. Phytomedicine Suppl VI 14: in press (2007).
22. Matthys, H.; Heger, M.: Treatment of Acute Bronchitis with a Liquid Herbal Drug Preparation from Pelargonium sidoides (EPs® 7630): A Randomised, Double-Blind, Placebo-Controlled, Multi-Centre Study. in preparation (2007).
23. Matthys, H.; Kamin, W.; Funk, P.; Heger, M.: Pelargonium sidoides preparation (EPs® 7630) in the treatment of acute bronchitis in adults and children. Phytomedicine Suppl VI 14, in press (2007).
24. Neugebauer, P.; Mickenhagen, A.; Siefer, O.; Walger, M.: A new approach to pharmacological effects on ciliary beat frequency in cell cultures - exemplary measurements under Pelargonium sidoides extract. Phytomedicine 12, 47-52 (2005).
25. Nöldner, M.; Schötz, K.: Inhibition of Lipopolysaccharid- Induced Sickness Behavior by a Dry Extract from the Roots of Pelargonium Sidoides (EPs® 7630) in Mice. Phytomedicine Suppl. VI 14, in press (2007).
26. Radtke, O.A.; Kiderlen, A. F.; Kayser, O.; Kolodziej, H.: Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania majir-infected macrophage-like RAW 264.7 cells treated with gallic acid. Planta Medica 70, 924-928 (2005).
27. Roots, I.; Arold, G.; Dienel, A.; Meng, G.; Wollny, A.; Bauer, S.: Placebokontrollierte doppelblinde Interaktions-studie mit Pelargonium-sidoides- Extrakt und Penicillin V bei gesunden Probanden. Phytopharmaka und Phytotherapie 2004 - Forschung und Praxis, Berlin 2004. Abstract.
28. Schötz, K.; Nöldner, M.: Mass spectroscopic characterization of oligomeric proanthocyanidins derived from an extract of Pelargonium sidoides roots (EPs® 7630) and pharmacological screening in CNS models. Phytomedicine Suppl. VI 14, in press (2007).
29. Trun, W.; Kiderlen, A. F.; Kolodziej, H.: Nitric oxide synthase and cytokines gene expression analyses in Leishmania-infected RAW 264.7 cells treated with an extract of Pelargonium sidoides (EPs® 7630). Phytomedicine Suppl. VI 14, in press (2007).