메뉴 건너뛰기




Volumn 14, Issue SUPPL. 1, 2007, Pages 18-26

In vitro evaluation of antibacterial and immunomodulatory activities of Pelargonium reniforme, Pelargonium sidoides and the related herbal drug preparation EPs® 7630

Author keywords

Antibacterial activity; Cytokines; Gene expressions; Immunomodulation; Nitric oxides; Pelargonium sidoides

Indexed keywords

5,6,7 TRIMETHOXYCOUMARIN; 6,8 DIHYDROXY 5,7 DIMETHOXYCOUMARIN; AGLYCONE; ALPHA INTERFERON; COUMARIN DERIVATIVE; CYTOKINE; EPS 7630; GALLIC ACID; GALLIC ACID METHYL ESTER; GAMMA INTERFERON; GLYCOSIDE; HERBACEOUS AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; MESSENGER RNA; NITRIC OXIDE; PELARGONIUM RENIFORME EXTRACT; PELARGONIUM SIDOIDES EXTRACT; PLANT EXTRACT; PROANTHOCYANIDIN DERIVATIVE; SCOPOLETIN; STIBOGLUCONATE SODIUM; TUMOR NECROSIS FACTOR ALPHA; UMCKALIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 33846833861     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2006.11.020     Document Type: Review
Times cited : (102)

References (41)
  • 1
    • 0034954034 scopus 로고    scopus 로고
    • Interferons α and ß as immune regulators - a new look
    • Biron C.A. Interferons α and ß as immune regulators - a new look. Immunity 41 (2001) 661-664
    • (2001) Immunity , vol.41 , pp. 661-664
    • Biron, C.A.1
  • 2
    • 0017373084 scopus 로고
    • ® - Droge der afrikanischen Volksmedizin
    • ® - Droge der afrikanischen Volksmedizin. Dtsch. Apoth. Ztg. 117 (1977) 1655-1660
    • (1977) Dtsch. Apoth. Ztg. , vol.117 , pp. 1655-1660
    • Bladt, S.1
  • 3
    • 0038570341 scopus 로고    scopus 로고
    • ® versus symptomatische Therapie in der Behandlung der Angina catarrhalis
    • ® versus symptomatische Therapie in der Behandlung der Angina catarrhalis. Päd 6 (2000) 2-8
    • (2000) Päd , vol.6 , pp. 2-8
    • Blochin, B.1    Heger, M.2
  • 4
    • 0037894053 scopus 로고    scopus 로고
    • ® im Vergleich mit Acetylcystein bei Kindern mit akuter Bronchitis
    • ® im Vergleich mit Acetylcystein bei Kindern mit akuter Bronchitis. Der. Kassenarzt. 49 (1999) 46-49
    • (1999) Der. Kassenarzt. , vol.49 , pp. 46-49
    • Blochin, B.1    Haidvogl, M.2    Heger, M.3
  • 5
    • 33846849128 scopus 로고    scopus 로고
    • ® 7630) inhibits the interactions of group A streptococci and host epithelia in-vitro. Phytomedicine, this issue.
  • 6
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
    • Ding A.H., Nathan C.F., and Stuehr D.J. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141 (1988) 2407-2412
    • (1988) J. Immunol. , vol.141 , pp. 2407-2412
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 7
    • 0005403305 scopus 로고    scopus 로고
    • Umckaloabo-eine phytotherapeutische Alternative bei akuter Bronchitis im Kindesalter
    • Dome L., and Schuster R. Umckaloabo-eine phytotherapeutische Alternative bei akuter Bronchitis im Kindesalter. Ärztezeitschr. Naturheilv. 37 (1996) 216-222
    • (1996) Ärztezeitschr. Naturheilv. , vol.37 , pp. 216-222
    • Dome, L.1    Schuster, R.2
  • 8
    • 0344193087 scopus 로고    scopus 로고
    • IFN-γ expression in macrophages and its possible biological significance
    • Gessani S., and Belardelli F. IFN-γ expression in macrophages and its possible biological significance. Cytokine Growth Factor Rev. 9 (1998) 117-123
    • (1998) Cytokine Growth Factor Rev. , vol.9 , pp. 117-123
    • Gessani, S.1    Belardelli, F.2
  • 9
    • 33846818495 scopus 로고    scopus 로고
    • Gödecke, T., 2005. Phytochemische und pharmakologische Untersuchungen an Pelargonium sidoides DC. Dissertation, Freie Universität. Berlin.
  • 10
    • 0038231624 scopus 로고    scopus 로고
    • ® 7630) versus Placebo bei akuter Bronchitis
    • Schulz V., Rietbrock N., Roots I., and Loew D. (Eds), Steinkopff-Verlag, Darmstadt
    • ® 7630) versus Placebo bei akuter Bronchitis. In: Schulz V., Rietbrock N., Roots I., and Loew D. (Eds). Phytopharmaka VII - Forschung und klinische Anwendung (2002), Steinkopff-Verlag, Darmstadt 3-12
    • (2002) Phytopharmaka VII - Forschung und klinische Anwendung , pp. 3-12
    • Golovatiouk, A.1    Chuchalin, A.G.2
  • 12
    • 0038570342 scopus 로고    scopus 로고
    • ® 7630) im Vergleich zu Placebo
    • Schulz V., Rietbrock N., Roots I., and Loew D. (Eds), Steinkopff-Verlag, Darmstadt
    • ® 7630) im Vergleich zu Placebo. In: Schulz V., Rietbrock N., Roots I., and Loew D. (Eds). Phytopharmaka VII - Forschung und klinische Anwendung (2002), Steinkopff-Verlag, Darmstadt 13-25
    • (2002) Phytopharmaka VII - Forschung und klinische Anwendung , pp. 13-25
    • Heger, M.1    Bereznoy, V.V.2
  • 14
    • 0008642981 scopus 로고    scopus 로고
    • ® - Late vindication of a secret remedy
    • ® - Late vindication of a secret remedy. Pharm. Historian 26 (1996) 2-4
    • (1996) Pharm. Historian , vol.26 , pp. 2-4
    • Helmstädter, A.1
  • 15
    • 0029060728 scopus 로고
    • Inhibition of intestinal chloride secretion by proanthocyanidins from Guazuma ulmifolia
    • Hör M., Rimpler H., and Heinrich M. Inhibition of intestinal chloride secretion by proanthocyanidins from Guazuma ulmifolia. Planta Med. 61 (1995) 208-212
    • (1995) Planta Med. , vol.61 , pp. 208-212
    • Hör, M.1    Rimpler, H.2    Heinrich, M.3
  • 16
    • 0003755578 scopus 로고    scopus 로고
    • Natal University Press, Pietermaritzburg
    • Hutchings A. Zulu Medicinal Plants (1996), Natal University Press, Pietermaritzburg
    • (1996) Zulu Medicinal Plants
    • Hutchings, A.1
  • 17
    • 0031439361 scopus 로고    scopus 로고
    • Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme
    • Kayser O., and Kolodziej H. Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme. Planta Med. 63 (1997) 508-510
    • (1997) Planta Med. , vol.63 , pp. 508-510
    • Kayser, O.1    Kolodziej, H.2
  • 18
    • 0035067136 scopus 로고    scopus 로고
    • Immunomodulatory principles of Pelargonium sidoides
    • Kayser O., Kolodziej H., and Kiderlen A.F. Immunomodulatory principles of Pelargonium sidoides. Phytother. Res. 15 (2001) 122-126
    • (2001) Phytother. Res. , vol.15 , pp. 122-126
    • Kayser, O.1    Kolodziej, H.2    Kiderlen, A.F.3
  • 19
    • 0037894050 scopus 로고    scopus 로고
    • Pelargonium reniforme and Pelargonium sidoides: their botany, chemistry and medicinal use
    • Lis-Balchin M. (Ed), Taylor & Francis, London
    • Kolodziej H. Pelargonium reniforme and Pelargonium sidoides: their botany, chemistry and medicinal use. In: Lis-Balchin M. (Ed). Geranium and Pelargonium (2002), Taylor & Francis, London 262-290
    • (2002) Geranium and Pelargonium , pp. 262-290
    • Kolodziej, H.1
  • 20
    • 0031809068 scopus 로고    scopus 로고
    • Pelargonium sidoides DC. - Neueste Erkenntnisse zum Verständnis des Phytotherapeutikums Umckaloabo
    • Kolodziej H., and Kayser O. Pelargonium sidoides DC. - Neueste Erkenntnisse zum Verständnis des Phytotherapeutikums Umckaloabo. Z. Phytother. 19 (1998) 141-151
    • (1998) Z. Phytother. , vol.19 , pp. 141-151
    • Kolodziej, H.1    Kayser, O.2
  • 21
    • 0343452257 scopus 로고
    • Arzneilich verwendete Pelargonien aus Südafrika
    • Kolodziej H., Kayser O., and Gutmann M. Arzneilich verwendete Pelargonien aus Südafrika. Dtsch. Apoth. Ztg. 135 (1995) 853-864
    • (1995) Dtsch. Apoth. Ztg. , vol.135 , pp. 853-864
    • Kolodziej, H.1    Kayser, O.2    Gutmann, M.3
  • 22
    • 0034827105 scopus 로고    scopus 로고
    • Proanthocyanidins and related compounds: antileishmanial activity and modulatory effects on nitric oxide and tumor necrosis factor-α-release in the murine macrophage-like cell line RAW 264.7
    • Kolodziej H., Kayser O., Kiderlen A.F., Ito H., Hatano T., Yoshida T., and Foo L.Y. Proanthocyanidins and related compounds: antileishmanial activity and modulatory effects on nitric oxide and tumor necrosis factor-α-release in the murine macrophage-like cell line RAW 264.7. Biol. Pharm. Bull. 24 (2001) 1016-1021
    • (2001) Biol. Pharm. Bull. , vol.24 , pp. 1016-1021
    • Kolodziej, H.1    Kayser, O.2    Kiderlen, A.F.3    Ito, H.4    Hatano, T.5    Yoshida, T.6    Foo, L.Y.7
  • 23
    • 0037573531 scopus 로고    scopus 로고
    • Pharmacological profile of extracts of Pelargonium sidoides and their constituents
    • Kolodziej H., Kayser O., Radtke O.A., Kiderlen A.F., and Koch E. Pharmacological profile of extracts of Pelargonium sidoides and their constituents. Phytomedicine 10 Suppl. IV (2003) 18-24
    • (2003) Phytomedicine , vol.10 , Issue.SUPPL. IV , pp. 18-24
    • Kolodziej, H.1    Kayser, O.2    Radtke, O.A.3    Kiderlen, A.F.4    Koch, E.5
  • 24
    • 27544505238 scopus 로고    scopus 로고
    • Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells
    • Kolodziej H., Burmeister A., Trun W., Radtke O.A., Kiderlen A.F., Ito H., Hatano T., Yoshida T., and Foo L.Y. Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells. Bioorg. Med. Chem. 13 (2005) 6470-6476
    • (2005) Bioorg. Med. Chem. , vol.13 , pp. 6470-6476
    • Kolodziej, H.1    Burmeister, A.2    Trun, W.3    Radtke, O.A.4    Kiderlen, A.F.5    Ito, H.6    Hatano, T.7    Yoshida, T.8    Foo, L.Y.9
  • 25
    • 3242758868 scopus 로고    scopus 로고
    • Antioxidant properties of phenolic compounds from Pelargonium reniforme
    • Latté K.P., and Kolodziej H. Antioxidant properties of phenolic compounds from Pelargonium reniforme. J. Agric. Food Chem. 52 (2004) 4899-4902
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 4899-4902
    • Latté, K.P.1    Kolodziej, H.2
  • 26
    • 0019972123 scopus 로고
    • Production of high titers of interferon gamma by prestimulated spleen cells
    • Marcucci F., Klein B., Kirchner M., and Zawatzky R. Production of high titers of interferon gamma by prestimulated spleen cells. Eur. J. Immunol. 12 (1992) 787-790
    • (1992) Eur. J. Immunol. , vol.12 , pp. 787-790
    • Marcucci, F.1    Klein, B.2    Kirchner, M.3    Zawatzky, R.4
  • 28
    • 0023464378 scopus 로고
    • The interferon-macrophage alliance
    • Mogensen S.C., and Virelizier J.L. The interferon-macrophage alliance. Interferon 8 (1987) 55-84
    • (1987) Interferon , vol.8 , pp. 55-84
    • Mogensen, S.C.1    Virelizier, J.L.2
  • 29
    • 0025883342 scopus 로고
    • Nitric oxide: physiology, pathophysiology, and pharmacology
    • Moncada S., Palmer R.M.J., and Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43 (1991) 109-142
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 30
    • 0026034432 scopus 로고
    • Role of nitric oxide synthesis in macrophage antimicrobial activity
    • Nathan C.F., and Hibbs J.B. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 3 (1991) 65-70
    • (1991) Curr. Opin. Immunol. , vol.3 , pp. 65-70
    • Nathan, C.F.1    Hibbs, J.B.2
  • 31
    • 0027244724 scopus 로고
    • Inflammation, immunoregulation, and inducible nitric oxide synthase
    • Nussler A.K., and Biliar T.R. Inflammation, immunoregulation, and inducible nitric oxide synthase. J. Leukocyte Biol. 54 (1993) 171-178
    • (1993) J. Leukocyte Biol. , vol.54 , pp. 171-178
    • Nussler, A.K.1    Biliar, T.R.2
  • 32
    • 7644221802 scopus 로고    scopus 로고
    • Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania major-infected macrophage-like RAW 264.7 cells treated with gallic acid
    • Radtke O.A., Kiderlen A.F., Kayser O., and Kolodziej H. Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania major-infected macrophage-like RAW 264.7 cells treated with gallic acid. Planta Med. 70 (2004) 924-928
    • (2004) Planta Med. , vol.70 , pp. 924-928
    • Radtke, O.A.1    Kiderlen, A.F.2    Kayser, O.3    Kolodziej, H.4
  • 33
    • 0025940127 scopus 로고
    • Role of inorganic nitrogen oxides and tumor necrosis factor alpha in killing Leishmania donovani amastigotes in gamma interferon-lipopolysaccharide-activated macrophages from Lshs and Lshr congenic mouse strains
    • Roach T.I., Kiderlen A.F., and Blackwell J.M. Role of inorganic nitrogen oxides and tumor necrosis factor alpha in killing Leishmania donovani amastigotes in gamma interferon-lipopolysaccharide-activated macrophages from Lshs and Lshr congenic mouse strains. Infect. Immun. 59 (1991) 3935-3944
    • (1991) Infect. Immun. , vol.59 , pp. 3935-3944
    • Roach, T.I.1    Kiderlen, A.F.2    Blackwell, J.M.3
  • 34
    • 0003214938 scopus 로고
    • Pflanzliche Gerbstoffe - Pharmakologie und Toxikologie
    • Scholz E. Pflanzliche Gerbstoffe - Pharmakologie und Toxikologie. Dtsch. Apoth. Ztg. 34 (1994) 3167-3179
    • (1994) Dtsch. Apoth. Ztg. , vol.34 , pp. 3167-3179
    • Scholz, E.1
  • 35
    • 0033825303 scopus 로고    scopus 로고
    • Interleukin-18 (IL-18) and infectious diseases, with special emphasis on diseases induced by intracellular pathogens
    • Sugawara I. Interleukin-18 (IL-18) and infectious diseases, with special emphasis on diseases induced by intracellular pathogens. Microbes Infect. 2 (2000) 1257-1263
    • (2000) Microbes Infect. , vol.2 , pp. 1257-1263
    • Sugawara, I.1
  • 36
    • 0028970060 scopus 로고
    • Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen specific adaptive immunity
    • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen specific adaptive immunity. Annu. Rev. Immunol. 13 (1995) 251-276
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 37
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3 (2003) 133-146
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 40
    • 0001203684 scopus 로고
    • Assays for immunmodulation and effects on mediators of inflammation
    • Dey P.M., and Harborne J.B. (Eds), Academic Press, London
    • Wagner H., and Jurcic K. Assays for immunmodulation and effects on mediators of inflammation. In: Dey P.M., and Harborne J.B. (Eds). Methods in Plant Biochemistry vol. 6 (1991), Academic Press, London 195-217
    • (1991) Methods in Plant Biochemistry , vol.6 , pp. 195-217
    • Wagner, H.1    Jurcic, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.