Substrate specificity of Escherichia coli thymidine phosphorylase

Biochemistry (Moscow)

Volumn 72, Issue 1, 2007, Pages 21-28

  Panova, N G ^a   Alexeev, C S ^a   Kuzmichov, A S ^a   Shcheveleva, E V ^a   Gavryushov, S A ^a   Polyakov, K M ^a   Kritzyn, A M ^a   Mikhailov, S N ^a   Esipov, R S ^b   Miroshnikov, A I ^b  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Analysis in terms of steric interactions; Inhibitors; Substrate specificity; Thymidine derivatives; Thymidine phosphorylase

Indexed keywords

AMINES; CHEMICAL MODIFICATION; DERIVATIVES; ESCHERICHIA COLI; MOLECULAR DYNAMICS; REACTION KINETICS;

STERIC INTERACTIONS; SUBSTRATE SPECIFICITY; THYMIDINE DERIVATIVES; THYMIDINE PHOSPHORYLASE;

ENZYMES;

ESCHERICHIA COLI;

NUCLEOSIDE; THYMIDINE; THYMIDINE PHOSPHORYLASE;

AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; METABOLISM; PH; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THYMIDINE; THYMIDINE PHOSPHORYLASE;

EID: 33846865559     PISSN: 00062979     EISSN: 16083040     Source Type: Journal    
DOI: 10.1134/S0006297907010026     Document Type: Article

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