Epidermodysplasia verruciformis and cutaneous human papillomavirus DNA, but not genital human papillomavirus DNAs, are frequently detected in vulvar and vaginal melanoma

American Journal of Dermatopathology

Volumn 29, Issue 1, 2007, Pages 13-17

  Rohwedder, Angela ^a   Slominski, Andrzej ^b   Wolff, Marisa ^c   Kredentser, Daniel ^d   Carlson, J Andrew ^c  

^a Biomed Molec Serv   (Germany)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c ALBANY MEDICAL COLLEGE   (United States)

^d St Peter's Hospital Albany   (United States)

Author keywords

HPV; Melanoma; Vagina; Virus; Vulva

Indexed keywords

VIRUS DNA;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BLUE NEVUS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; EPIDERMODYSPLASIA VERRUCIFORMIS; FEMALE; HUMAN; HUMAN TISSUE; LICHEN SCLEROSUS ET ATROPHICUS; MELANOMA; MUCOSA INFLAMMATION; POLYMERASE CHAIN REACTION; POSTMENOPAUSE; PRIORITY JOURNAL; TUMOR DIAGNOSIS; TUMOR GROWTH; VAGINA MUCOSA; VAGINA TUMOR; VIRUS STRAIN; VULVA TUMOR; WART VIRUS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; DNA PROBES, HPV; DNA, VIRAL; EPIDERMODYSPLASIA VERRUCIFORMIS; FEMALE; GENITAL DISEASES, FEMALE; HUMAN PAPILLOMAVIRUS 16; HUMANS; INFANT; MELANOMA; MIDDLE AGED; MUCOUS MEMBRANE; VAGINAL NEOPLASMS; VULVAR NEOPLASMS;

EID: 33846863114     PISSN: 01931091     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.dad.0000245202.59762.09     Document Type: Article

References (34)

1. McLaughlin CC, Wu XC, Jemal A, et al. Incidence of noncutaneous melanomas in the U.S. Cancer. 2005;103:1000-1007.
2. Ragnarsson-Olding BK. Primary malignant melanoma of the vulva: an aggressive tumor for modeling the genesis of non-UV light-associated melanomas. Acta Oncol. 2004;43:421-435.
3. Zaffar M, Scott HJ. Vaginal melanoma: a current review. J Obstet Gynaecol. 1998;18:516-519.
4. Rohwedder A, Philips B, Malfetano J, et al. Vulvar malignant melanoma associated with human papillomavirus DNA: report of two cases and review of literature. Am J Dermatopathol. 2002;24:230-240.
5. La Placa ML, Ambretti S, Bonvicini F, et al. Presence of high-risk mucosal human papillomavirus genotypes in primary melanoma and in acquired dysplastic melanocytic naevi. Br J Dermatol. 2005;152:909-914.
6. Forslund O, Ly H, Reid C, et al. A broad spectrum of human papillomavirus types is present in the skin of Australian patients with nonmelanoma skin cancers and solar keratosis. Br J Dermatol. 2003;149:64-73.
7. Orth G. Human papillomaviruses and the skin: more to be learned. J Invest Dermatol. 2004;123:XI-XIII.
8. Antonsson A, Erfurt C, Hazard K, et al. Prevalence and type spectrum of human papillomaviruses in healthy skin samples collected in three continents. J Gen Virol. 2003;84(pt 7):1881-1886.
9. Orth G. Human papillomaviruses associated with epidermodysplasia verruciformis in non-melanoma skin cancers: guilty or innocent? J Invest Dermatol. 2005;125:xii-xiii.
10. Shibata D. The polymerase chain reaction and the molecular genetic analysis of tissue biopsies. In: Herrington C, McGee JD, eds. Diagnostic Molecular Pathology: A Practical Approach. Oxford, England: IRL Press; 1992:85-111.
11. Chan SY, Delius H, Halpern AL, et al. Analysis of genomic sequences of 95 papillomavirus types: uniting typing, phylogeny, and taxonomy. J Virol. 1995;69:3074-3083.
12. Berkhout RJ, Bouwes Bavinck JN, ter Schegget J. Persistence of human papillomavirus DNA in benign and (pre)malignant skin lesions from renal transplant recipients. J Clin Microbiol. 2000;38:2087-2096.
13. Jablonska S, Orth G, Obalek S, et al. Cutaneous warts: clinical, histologic, and virologic correlations. Clin Dermatol. 1985;3:71-82.
14. Meisels A, Fortin R, Roy M. Condylomatous lesions of the cervix, II: cytologic, colposcopic and histopathologic study. Acta Cytol. 1977;21:379-390.
15. Morrison C, Eliezri Y, Magro C, et al. The histologic spectrum of epidermodysplasia verruciformis in transplant and AIDS patients. J Cutan Pathol. 2002;29:480-489.
16. Forslund O, Lindelof B, Hradil E, et al. High prevalence of cutaneous human papillomavirus DNA on the top of skin tumors but not in "stripped" biopsies from the same tumors. J Invest Dermatol. 2004;123:388-394.
17. Doorbar J. The papillomavirus life cycle. J Clin Virol. 2005;32(Suppl 1):S7-15.
18. Carlson JA, Mu XC, Slominski A, et al. Melanocytic proliferations associated with lichen sclerosus. Arch Dermatol. 2002;138:77-87.
19. Jablonska S, Orth G, Jarzabek-Chorzelska M, et al. Epidermodysplasia verruciformis versus disseminated verrucae planae: is epidermodysplasia verruciformis a generalized infection with wart virus? J Invest Dermatol. 1979;72:114-119.
20. Jablonska S, Majewski S. Epidermodysplasia verruciformis: immunological and clinical aspects. Curr Top Microbiol Immunol. 1994;186:157-175.
21. Egawa K, Honda Y, Inaba Y, et al. Pigmented viral warts: a clinical and histopathological study including human papillomavirus typing. Br J Dermatol. 1998;138:381-389.
22. Blessing K, McLaren KM, Maloney DJ, et al. Melanocytic proliferation in condylomata acuminata: a report of two cases and investigation by in situ hybridisation. Acta Derm Venereol. 1989;69:238-241.
23. Baron JM, Rubben A, Grussendorf-Conen EI. HPV 18-induced pigmented bowenoid papulosis of the neck. J Am Acad Dermatol. 1999;40:633-634.
24. Clavel CE, Huu VP, Durlach AP, et al. Mucosal oncogenic human papillomaviruses and extragenital Bowen disease. Cancer. 1999;86:282-287.
25. Carlson JA, Grabowski R, Chichester P, et al. Comparative immunophenotypic study of lichen sclerosus: epidermotropic CD57+ lymphocytes are numerous: implications for pathogenesis. Am J Dermatopathol. 2000;22:7-16.
26. Carlson JA, Malfetano J, Rohwedder A. Genital and epidermodysplasia verruciformis associated HPV DNA is frequently found in lichen sclerosus. J Cutan Pathol. 2000;27:552.
27. Steenbergen RD, de Wilde J, Wilting SM, et al. HPV-mediated transformation of the anogenital tract. J Clin Virol. 2005;32(Suppl 1):S25-33.
28. Ueda Y, Enomoto T, Miyatake T, et al. Analysis of clonality and HPV infection in benign, hyperplastic, premalignant, and malignant lesions of the vulvar mucosa. Am J Clin Pathol. 2004;122:266-274.
29. Lotem M, Anteby S, Peretz T, et al. Mucosal melanoma of the female genital tract is a multifocal disorder. Gynecol Oncol. 2003;88:45-50.
30. Kerley SW, Blute ML, Keeney GL. Multifocal malignant melanoma arising in vesicovaginal melanosis. Arch Pathol Lab Med. 1991;115:950-952.
31. Spatz A, Zimmermann U, Bachollet B, et al. Malignant blue nevus of the vulva with late ovarian metastasis. Am J Dermatopathol. 1998;20:408-412.
32. Requena L, Carlson J. Melanoma arising from a blue nevus. In: LeBoit P, Burg G, Weedon D, Sarasin A, eds. WHO Classification of Tumors: Pathology & Genetics of Skin Tumors. Lyon, France: IARC Press; 2006 p. 79-82.
33. Hassanein AM, Mrstik ME, Hardt NS, et al. Malignant melanoma associated with lichen sclerosus in the vulva of a 10-year-old. Pediatr Dermatol. 2004;21:473-476.
34. Buscher K, Trefzer U, Hofmann M, et al. Expression of human endogenous retrovirus K in melanomas and melanoma cell lines. Cancer Res. 2005;65:4172-4180.