High prevalence of cutaneous human papillomavirus DNA on the top of skin tumors but not in "stripped" biopsies from the same tumors

Journal of Investigative Dermatology

Volumn 123, Issue 2, 2004, Pages 388-394

  Forslund, Ola ^a   Lindelöf, Bernt ^b   Hradil, Eva ^a   Nordin, Peter ^c   Stenquist, Bo ^d   Kirnbauer, Reinhard ^e   Slupetzky, Katharina ^e   Dillner, Joakim ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c Dermatology Clinic Läkarhuset   (Sweden)

^d SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

HPV; PCR; Superficial; Tumors

Indexed keywords

VIRUS DNA;

ACTINIC KERATOSIS; ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOCOMPETENCE; MAJOR CLINICAL STUDY; MALE; PATIENT; PREVALENCE; PRIORITY JOURNAL; SAMPLE; SEBORRHEIC KERATOSIS; SKIN BIOPSY; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR BIOPSY; WART VIRUS;

EID: 3242670400     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.23205.x     Document Type: Article

References (47)

1. Antonsson A, Erfurt C, Hazard H, et al: Prevalence and type spectrum of human papillomaviruses in healthy skin samples collected in three continents. J Gen Virol 84:1881-1886, 2003a
2. Antonsson A, Forslund O, Ekberg H, Sterner G, Hansson BG: The ubiquity and impressive genomic diversity of human skin papillomaviruses suggest a commensalic nature of these viruses. J Virol 74:11636-11641, 2000
3. Antonsson A, Karanfilovska S, Lindqvist PG, Hansson BG: General acquisition of human papillomavirus infections of skin occurs in early infancy. J Clin Microbiol 41:2509-2514, 2003b
4. Astori G, Lavergne D, Benton C, Hockmayr B, Egawa K, Garbe C, de Villiers EM: Human papillomaviruses are commonly found in normal skin of immunocompetent hosts. J Invest Dermatol 110:752-755, 1998
5. Bens G, Wieland U, Hofmann A, Hopfl R, Pfister H: Detection of new human papillomavirus sequences in skin lesions of a renal transplant recipient and characterization of one complete genome related to epidermodysplasia verruciformis-associated types. J Gen Virol 79:779-787, 1998
6. Bouwes Bavinck JN, Feltkarmp M, Struijk L, ter Scheggett J: Human papillomavirus infection and skin cancer risk in organ transplant recipients. J Investig Dermatol Symp Proc 6:207-211, 2001
7. Bouwes Bavinck JN, Hardie DR, Green A, et al: The risk of skin cancer in renal transplant recipients in Queensland, Australia. A follow-up study. Transplantation 61:715-721, 1996
8. Boxman IL, Berkhout RJ, Mulder LH, Wolkers MC, Bouwes Bavinck JN, Vermeer BJ, ter Schegget J: Detection of human papillomavirus DNA in plucked hairs from renal transplant recipients and healthy volunteers. J Invest Dermatol 108:712-715, 1997
9. Boxman IL, Mulder LH, Vermeer BJ, Bavinck JN, ter Schegget J, Ponec M: HPV-DNA is not detectable in outgrowing cells from explant cultures of skin lesions established at the air-liquid-interface. J Med Virol 61:281-288, 2000a
10. Boxman IL, Russell A, Mulder LH, Bavinck JN, Schegget JT, Green A: Case-control study in a subtropical Australian population to assess the relation between non-melanoma skin cancer and epidermodysplasia verruciformis human papillomavirus DNA in plucked eyebrow hairs. The Nambour Skin Cancer Prevention Study Group. Int J Cancer 86:118-121, 2000b
11. Burd EM: Human papillomavirus and cervical cancer. Clin Microbiol Rev 16:1-17, 2003
12. Caldeira S, Zehbe I, Accardi R, et al: The E6 and E7 proteins of the cutaneous human papillomavirus type 38 display transforming properties. J Virol 77:2195-2206, 2003
13. Chan SY, Delius H, Halpern AL, Bernard HU: Analysis of genomic sequences of 95 papillomavirus types: Uniting typing, phylogeny, and taxonomy. J Virol 69:3074-3083, 1995
14. Corley E, Pueyo S, Goc B, Diaz A, Zorzopulos J: Papillomaviruses in human skin warts and their incidence in an Argentine population. Diagn Microbiol Infect Dis 10:93-101, 1988
15. de Roda Husman AM, Snijders PJ, Stel HV, van den Brule AJ, Meijer CJ, Walboomers JM: Processing of long-stored archival cervical smears for human papillomavirus detection by the polymerase chain reaction. Br J Cancer 72:412-417, 1995
16. Egawa K: Do human papillomaviruses target epidermal stem cells? Dermatology 207:251-254, 2003
17. Forslund O, Antonsson A, Edlund K, et al: Population-based type-specific prevalence of high-risk human papillomavirus infection in middle-aged Swedish Women. J Med Virol 66:535-541, 2002
18. Forslund O, Antonsson A, Nordin P, Stenquist B, Hansson BG: A broad range of human papillomavirus types detected with a general PCR method suitable for analysis of cutaneous tumours and normal skin. J Gen Virol 80:2437-2443, 1999
19. Forslund O, Ly H, Reid C, Higgins G: A broad spectrum of human papillomavirus types is present in the skin of Australian patients with non-melanoma skin cancers and solar keratosis. Br J Dermatol 149:64-73, 2003
20. Hartevelt MM, Bavinck JN, Kootte AM, Vermeer BJ, Vandenbroucke JP: Incidence of skin cancer after renal transplantation in The Netherlands. Transplantation 49:506-509, 1990
21. Harwood CA, Surentheran T, McGregor JM, Spink PJ, Leigh IM, Breuer J, Proby CM: Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals. J Med Virol 61:289-297, 2000
22. Iftner T, Bierfelder S, Csapo Z, Pfister H: Involvement of human papillomavirus type 8 genes E6 and E7 in transformation and replication. J Virol 62:3655-3661, 1988
23. Iftner T, Elbel M, Schopp B, Hiller T, Loizou JI, Caldecott KW, Stubenrauch F: Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1. EMBO J 21:4741-4748, 2002
24. Jackson S, Harwood C, Thomas M, Banks L, Storey A: Role of bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins. Genes Dev 14:3065-3073, 2000
25. Jackson S, Storey A: E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage. Oncogene 19:592-598, 2000
26. Kawashima M, Favre M, Obalek S, Jablonska S, Orth G: Premalignant lesions and cancers of the skin in the general population: Evaluation of the role of human papillomaviruses. J Invest Dermatol 95:537-542, 1990
27. Kiviat NB: Papillomaviruses in non-melanoma skin cancer: Epidemiological aspects. Semin Cancer Biol 9:397-403, 1999
28. Kiyono T, Nagashima K, Ishibashi M: The primary structure of major viral RNA in a rat cell line transfected with type 47 human papillomavirus DNA and the transforming activity of its cDNA and E6 gene. Virology 173:551-565, 1989
29. Langeveld-Wildschut EG, van Marion AM, Thepen T, Mudde GC, Bruijnzeel PL, Bruijnzeel-Koomen CA: Evaluation of variables influencing the outcome of the atopy patch test. J Allergy Clin Immunol 96:66-73, 1995
30. Leffell DJ: The scientific basis of skin cancer. J Am Acad Dermatol 42:18-22, 2000
31. Lindelof B, Sigurgeirsson B, Gabel H, Stern RS: Incidence of skin cancer in 5356 patients following organ transplantation. Br J Dermatol 143:513-519, 2000
32. Meyer T, Arndt R, Christophers E, Nindl I, Stockfleth E: Importance of human papillomaviruses for the development of skin cancer. Cancer Detect Prev 25:533-547, 2001
33. Meyer J, Arndt R, Christophers E, Stockfleth E: Frequency and spectrum of HPV types detected in cutaneous squamous-cell carcinomas depend on the HPV detection system: A comparison of four PCR assays. Dermatology 201:204-211, 2000
34. Perez-Losada J, Balmain A: Stem-cell hierarchy in skin cancer. Nat Rev Cancer 3:434-443, 2003
35. Pfister H, Fuchs PG, Majewski S, Jablonska S, Pniewska I, Malejczyk M: High prevalence of epidermodysplasia verruciformis-associated human papillomavirus DNA in actinic keratoses of the immunocompetent population. Arch Dermatol Res 295:273-279, 2003
36. Pfister H, Ter Schegget J: Role of HPV in cutaneous premalignant and malignant tumors. Clin Dermatol 15:335-347, 1997
37. Purdie KJ, Pennington J, Proby CM, Khalaf S, de Villiers EM, Leigh IM, Storey A: The promoter of a novel human papillomavirus (HPV77) associated with skin cancer displays UV responsiveness, which is mediated through a consensus p53 binding sequence. EMBO J 18:5359-5369, 1999
38. Purdie KJ, Sexton CJ, Proby CM, Glover MT, Williams AT, Stables JN, Leigh IM: Malignant transformation of cutaneous lesions in renal allograft patients: A role for human papillomavirus. Cancer Res 53:5328-5333, 1993
39. Rohwedder A, Keminer O, Hendricks C, Schaller J: Detection of HPV DNA in Trichilemmomas by polymerase chain reaction. J Med Virol 51:119-125, 1997
40. Ruhland A, de Villiers EM: Opposite regulation of the HPV 20-URR and HPV 27-URR promoters by ultraviolet irradiation and cytokines. Int J Cancer 91:828-834, 2001
41. Sambrook JE, Fritsch F, Maniatis T: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989
42. Schmitt A, Rochat A, Zeltner R, Borenstein L, Barrandon Y, Wettstein FO, Iftner T: The primary target cells of the high-isk cottontail rabbit papillomavirus colocalize with hair follicle stem cells. J Virol 70:1912-1922, 1996
43. Shamanin V, zur Hausen H, Lavergne D, et al: Human papillomavirus infections in nonmelanoma skin cancers from renal transplant recipients and nonimmunosuppressed patients. J Natl Cancer Inst 88:802-811, 1996
44. Steger G, Pfister H: In vitro expressed HPV 8 E6 protein does not bind p53. Arch Virol 125:355-360, 1992
45. Tengvall Linder M, Johansson C, Scheynius A, Wahlgren C: Positive atopy patch test reactions to Pityrosporum orbiculare in atopic dermatitis patients. Clin Exp Allergy 30:122-131, 2000
46. Tommasino M, Accardi R, Caldeira S, Dong W, Malanchi I, Smet A, Zehbe I: The role of TP53 in cervical carcinogenes s. Hum Mutat 21:307-312, 2003
47. Wieland U, Ritzkowsky A, Stoltidis M, et al: Communication: Papillomavirus DNA in basal cell carcinomas of immunocompetent patients: an accidental association. J Invest Dermatol 115:124-128, 2000