Topical delivery of N-alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of theophylline (ThH)

International Journal of Pharmaceutics

Volumn 332, Issue 1-2, 2007, Pages 64-71

  Majumdar, Susruta ^a   Sloan, K B ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Lipid solubility; NANAOCAM; Permeation; Prodrugs; Roberts Sloan equation; Theophylline; Water solubility

Indexed keywords

N METHYL N ETHYLOXYCARBONYLAMINOMETHYLTHEOPHYLLINE; OXYCARBONYLAMINOMETHYL DERIVATIVE; PRODRUG; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG SYNTHESIS; FEMALE; HAIRLESS MOUSE; LIPID SOLUBILITY; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL;

ADMINISTRATION, TOPICAL; ALKANES; ANIMALS; BUFFERS; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHARMACEUTICAL; DIFFUSION; DIFFUSION CHAMBERS, CULTURE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; METHYLAMINES; MICE; MICE, INBRED HRS; MODELS, BIOLOGICAL; MYRISTATES; PHOSPHODIESTERASE INHIBITORS; PREDICTIVE VALUE OF TESTS; PRODRUGS; SKIN ABSORPTION; SOLUBILITY; SOLVENTS; THEOPHYLLINE; TRANSITION TEMPERATURE; WATER;

EID: 33846851514     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.09.034     Document Type: Article

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