Endometrial evaluation in menopausal women after six months of isoflavones;Avaliação do endométrio em menopausadas após uso de isoflavonas

Revista da Associacao Medica Brasileira

Volumn 52, Issue 6, 2006, Pages 419-423

  Wolff, Luis Paulo Galvão ^a   Martins, Marcos Roberto ^a   Bedone, Aloísio José ^a   Monteiro, Ilza Maria Urbano ^a,b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b NONE   (Brazil)

Author keywords

Endometrium; Hysteroscopy; Isoflavones; Menopause

Indexed keywords

ISOFLAVONE DERIVATIVE;

ADULT; ARTICLE; BIOPSY; DRUG EFFECT; ENDOMETRIUM; ENDOMETRIUM HYPERPLASIA; FEMALE; HOT FLUSH; HUMAN; HYPERPLASIA; HYSTEROSCOPY; MENOPAUSE; MIDDLE AGED; PATHOLOGY; PROSPECTIVE STUDY; TIME; UTERUS BLEEDING; UTERUS DISEASE;

ADULT; BIOPSY; ENDOMETRIAL HYPERPLASIA; ENDOMETRIUM; FEMALE; HOT FLASHES; HUMANS; HYPERPLASIA; HYSTEROSCOPY; ISOFLAVONES; MENOPAUSE; MIDDLE AGED; PROSPECTIVE STUDIES; TIME FACTORS; UTERINE DISEASES; UTERINE HEMORRHAGE;

EID: 33846848090     PISSN: 01044230     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0104-42302006000600022     Document Type: Article

References (37)

1. Ferreira JAS. A perimenopausa. In: Fernandes CE, Melo NR, Wheba S. Climatério feminino. São Paulo: Ed. Lemos; 1999. p.41-56.
2. Navarro PAAS, Gomes FM, Azevedo GD, Costa FS, Ferriani RA, Iannetta O. Fatores locais envolvidos na etiopatogênese da osteoporose pósmenopausa. Reprod Clim. 2001;16:167-72.
3. Colditz GA. Relationship between estrogen levels: use of hormone replacement therapy and breast cancer. J Nat Cancer Inst. 1998;90:814-23.
4. Garnet AL, Howard JL, Kaunitz AM, Andrew M, Barad DH, Beresford SAA, et al. Effects of estrogen plus progestin on gynecologic cancers and associated diagnostic procedures: The Women's Health Initiative Randomized Trial. JAMA. 2003;290:1739-48.
5. Hays J, Ockene JK, Brunner RL, Kotchen JM, Manson JE, Patterson RE, et al. Effects of estrogen plus progestin on health-related quality of life. N Engl J Med. 2003;348:1839-54.
6. American Cancer Society. American cancer statistics 2004 [online]. Atlanta; 2004. Avaliable from: http://www.cancer.org/downloads/STT/ CAF_finalPWSecured.pvx〉 [cited nov 2004].
7. Allred CD, Allred KF, Ju YH, Virant SM, Helferich WG. Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner. Cancer Res. 2001;61:5045-50.
8. Alves DL, Silva CR. Fitohormônios: abordagem natural da terapia hormonal. São Paulo: Atheneu; 2002. p.1-54.
9. Nachtigall LE. Isoflavones in the management of menopause. J Br Menopause Soc. 2001;(Suppl 1):8-11.
10. Wender, M.C.;Campos, L.S. Fitoestrogênios: examinando as evidências do seu emprego no climatério. Reprod Clim. 2001;16:155-62.
11. Lethaby AE, Konenberg F, Roberts H, Eden J. Phytoestrogens for menopausal symptoms (Protocol for a Cochrane Review). Cochrane Library; 1 (1) [online]. Avaliable from: http://www.bireme.br/cgi-bin/wxislind.exe/iah-cochrany. [cited maio 2002].
12. Dornstauder E, Jisa E, Unterrieder I, Krenn, L, Kubelka W, Jungbauer A. Estrogenic activity of two standardized red clover extracts (MenoflavonÒ) intended for large scale use in hormone replacement therapy. J Steroid Biochem Mol Biol. 2001;78:67-75.
13. Boersma BJ, Barnes S, Kirk M, Wang CC, Smith M, Kim H, et al. Soy isoflavonoids and cancer metabolism at the target site. Mutat Res. 2001;480-481:121-7.
14. Lian Z, Niwa K, Tagami K, Hashimoto M, Gao, J, Yokoyama Y, et al. Preventive effects of isoflavones, genistein and daidzein, on estradiol-17b-related endometrial carcinogenesis in mice. Jpn J Cancer Res. 2001;92:726-34.
15. Couse JF, Lindzeu J, Grandien K, Gustafsson JÁ, Korach KS. Tissue distribution and quantitative analysis of estrogen receptor a (ERa) and estrogen receptor b (ERb) messenger ribonucleic acid in the wild-type and ERa-Knockout mouse. Endocrinology. 1997; 138:4613-21.
16. a ed. São Paulo: Ed. Roca; 1999. p.135-47.
17. Utsunomiya H, Suzuki T, Harada N, Kiyoshi I, Matsuzaki S, Konnor R, et al. Analysis of estrogen receptor a and b in endometrial carcinomas: correlation with ERb and clinicopathologic findings in 45 cases. Int J Gynecol Pathol. 2000;19:335-41.
18. Morito K, Hirose T, Kinjo J, Hirakawa T, Okawa M, Nohara T. Interaction of phytoestrogens with estrogen receptors a and b. Biol Pharm Bull 2001;24:351-6.
19. Urbanetz AA, Ribeiro MC. Fitoestrogênios: verdade ou mito? Reprod Clim.2001;16:92-7.
20. Mueller SO, Simon S, Chac K, Metzier M, Korach KS. Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor a (ERa) and b (ERb) in human cells. Toxicol Sci. 2004;80:14-25.
21. Piovesan AC, Simões RS, Mosquete R, Simões Junior MJ, Baracat EC. Efeitos das isoflavonas no tecido mamário. Femina. 2004;32:759-63.
22. Montgomery BE, Daum GS, Dunton CJ. Endometrial hyperplasia: a review. Obstet Gynecol Surv. 2004;59:368-78.
23. a assembléia geral, Edinburgo; 2000. Disponível em: http://wma.net/e/policy/b3.htm. [citado nov 2004].
24. Bourne T, Hamberger L, Hahlin M, Granberg S. Ultrasound in gynecology: endometrium. Int J Gynecol Obstet. 1997;56:115-27.
25. Moura AP, Pastore AR, Cerri GG. Endométrio. In: Pastore AR, Cerri GG. Ultra-sonografia: obstetrícia-ginecologia. São Paulo: Sarvier; 1997. p.555-71.
26. Epstein E, Valentin L. Intraobserver and interobserver reproducibility of ultrasound measurements of endometrial thickness in postmenopausal women. Ultrasound Obstet Gynecol. 2002;20:486-91.
27. a ed. New York: Ed. Springer-Verlag; 1987. p.322-37.
28. Unfer V, Casini ML, Costabile L, Mignosa M, Gerli S, Di Renzo GC. Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study. Fertil Steril. 2004;82:145-8.
29. Grodin JM, Stiiteri PK, Mac-Donald PC. Source of estrogen production in post-menopausal women. J Clin Endocrinol Metab. 1973;36:207-18.
30. Baber RJ, Templeman C, Morton T, Kelly GE, West L. Randomized placebo-controlled trial of an isoflavone supplement and menopausal symptons in women. Climateric. 1999;2:85-92.
31. Han KK, Soares Junior JM, Haidar MA, Lima GR, Baracat EC. Benefits of soy isoflavone therapeutic regimen on menopausal synptoms. Am Col Obstet Gynecol 2002; 99:389-94.
32. Penotti M, Fabio E, Modena BA, Rinaldi M, Omodei U, Vigano P. Effect of soy-derived isoflavones on hot flushes, endometrial thickness, and the pulsatility index of the uterine and cerebral arteries. Fertil Steril. 2003;79:1112-7.
33. Symonds I. Ultrasound, hysteroscopy and endometrial biopsy in the investigation of endometrial cancer. Best Pract Res Clin Obstet Gynaecol. 2001;15:381-91.
34. Diel P, Smolnikar K, Schultz T, Laudenbach-Leschowski U, Michna H, Vollmer G. Phytoestrogens and carcinogenesis - differential effects of genistein in experimental models of normal and malignant rat endometrium. Hum Reprod. 2001;16:997-1006.
35. Hale GE, Hughes CL, Robboy SJ, Argawal SK, Bievre M. A double-blind randomized study on the effects of red clover isoflavone on the endometrium. Menopause. 2001;8:338-46.
36. Bennets HW, Underwood EJ, Shier FL. A specific breeding problem of sheep on subterranean clover pastures in Western Australia. Aust Vet J. 1946;22:2-12.
37. Speroff L. The estrogen receptor: changing conceps. Clinical lessons from molecular biology. In: Coutinho EM, Spinola P. Reproductive medicine: a millennium review. New York: The Parthenon Publishing Group; 1999. p.155-61.