메뉴 건너뛰기




Volumn 6, Issue 1, 2007, Pages 173-183

HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID DERIVATIVE; CASPASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; GYRASE INHIBITOR; HU 331; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 33846840690     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0039     Document Type: Article
Times cited : (65)

References (42)
  • 1
    • 0034321937 scopus 로고    scopus 로고
    • Clinical applications of quinone-containing alkylating agents
    • Begleiter A. Clinical applications of quinone-containing alkylating agents. Front Biosci 2000;5:E153-71.
    • (2000) Front Biosci , vol.5
    • Begleiter, A.1
  • 4
    • 0036046302 scopus 로고    scopus 로고
    • Induction of apoptosis by redox-cycling quinones
    • Ollinger K, Kagedal K. Induction of apoptosis by redox-cycling quinones. Subcell Biochem 2002;36:151-70.
    • (2002) Subcell Biochem , vol.36 , pp. 151-170
    • Ollinger, K.1    Kagedal, K.2
  • 5
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics Adriamycin and daunomycin
    • Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics Adriamycin and daunomycin. Biochem Pharmacol 1999;57:727-41.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 6
    • 0037274873 scopus 로고    scopus 로고
    • Cardiac toxicity of antineoplastic anthracyclines
    • Zucchi R, Danesi R. Cardiac toxicity of antineoplastic anthracyclines. Curr Med Chem Anti-Canc Agents 2003; 3:151-71.
    • (2003) Curr Med Chem Anti-Canc Agents , vol.3 , pp. 151-171
    • Zucchi, R.1    Danesi, R.2
  • 7
    • 0036938433 scopus 로고    scopus 로고
    • Anthracycline-related toxicity requiring cardiac transplantation in long-term disease-free survivors with acute promyelocytic leukemia
    • Thomas X, Le QH, Fiere D. Anthracycline-related toxicity requiring cardiac transplantation in long-term disease-free survivors with acute promyelocytic leukemia. Ann Hematol 2002;81:504-7.
    • (2002) Ann Hematol , vol.81 , pp. 504-507
    • Thomas, X.1    Le, Q.H.2    Fiere, D.3
  • 8
    • 3142618434 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of quinonoid derivatives of cannabinoids
    • Kogan NM, Rabinowitz R, Levi P, et al. Synthesis and antitumor activity of quinonoid derivatives of cannabinoids. J Med Chem 2004; 47:3800-6.
    • (2004) J Med Chem , vol.47 , pp. 3800-3806
    • Kogan, N.M.1    Rabinowitz, R.2    Levi, P.3
  • 9
    • 0034905822 scopus 로고    scopus 로고
    • Regulation of the expression of CD45 isoforms in the Farage human B cell lymphoma line and its 10.6.1. subline
    • Rabinowitz R, Yu Y, Belov E, Shubinsky G, Ben-Bassat H, Schlesinger M. Regulation of the expression of CD45 isoforms in the Farage human B cell lymphoma line and its 10.6.1. subline. Leuk Lymphoma 2001;41: 643-54.
    • (2001) Leuk Lymphoma , vol.41 , pp. 643-654
    • Rabinowitz, R.1    Yu, Y.2    Belov, E.3    Shubinsky, G.4    Ben-Bassat, H.5    Schlesinger, M.6
  • 10
    • 0023130372 scopus 로고
    • Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
    • Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 1987;47:936-42.
    • (1987) Cancer Res , vol.47 , pp. 936-942
    • Carmichael, J.1    DeGraff, W.G.2    Gazdar, A.F.3    Minna, J.D.4    Mitchell, J.B.5
  • 11
    • 0025367455 scopus 로고
    • Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines
    • Rubinstein LV, Shoemaker RH, Paull KD, et al. Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines. J Natl Cancer Inst 1990;82:1113-8.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1113-1118
    • Rubinstein, L.V.1    Shoemaker, R.H.2    Paull, K.D.3
  • 12
    • 0034910124 scopus 로고    scopus 로고
    • Suppressors of cancer cell proliferation from fig (Ficus carica) resin: Isolation and structure elucidation
    • Rubnov S, Kashman Y, Rabinowitz R, Schlesinger M, Mechoulam R. Suppressors of cancer cell proliferation from fig (Ficus carica) resin: isolation and structure elucidation. J Nat Prod 2001; 64:993-6.
    • (2001) J Nat Prod , vol.64 , pp. 993-996
    • Rubnov, S.1    Kashman, Y.2    Rabinowitz, R.3    Schlesinger, M.4    Mechoulam, R.5
  • 13
    • 0026505943 scopus 로고
    • NAD(P)H:Quinone oxidoreductase gene expression in human colon carcinoma cells: Characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity
    • Traver RD, Horikoshi T, Danenberg KD, et al. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. Cancer Res 1992;52:797-802.
    • (1992) Cancer Res , vol.52 , pp. 797-802
    • Traver, R.D.1    Horikoshi, T.2    Danenberg, K.D.3
  • 14
    • 0028072167 scopus 로고
    • Inhibition of topoisomerase I activity by tyrphostin derivatives, protein tyrosine kinase blockers: Mechanism of action
    • Aflalo E, Seri I, Segal S, Gazit A, Priel E. Inhibition of topoisomerase I activity by tyrphostin derivatives, protein tyrosine kinase blockers: mechanism of action. Cancer Res 1994;54:5138-42.
    • (1994) Cancer Res , vol.54 , pp. 5138-5142
    • Aflalo, E.1    Seri, I.2    Segal, S.3    Gazit, A.4    Priel, E.5
  • 15
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 16
    • 0034431467 scopus 로고    scopus 로고
    • Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction
    • Ayala-Torres S, Chen Y, Svoboda T, Rosenblatt J, Van Houten B. Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction. Methods 2000;22:135-47.
    • (2000) Methods , vol.22 , pp. 135-147
    • Ayala-Torres, S.1    Chen, Y.2    Svoboda, T.3    Rosenblatt, J.4    Van Houten, B.5
  • 17
    • 0002130423 scopus 로고    scopus 로고
    • PCR-based assays for the detection and quantitation of DNA damage and repair
    • In: Pfeifer GP, editor. New York and London: Plenum Press
    • Yakes FM, Chen Y, Van Houten B. PCR-based assays for the detection and quantitation of DNA damage and repair, In: Pfeifer GP, editor. Technologies for detection of DNA damage and mutations. New York and London: Plenum Press; 1996. p. 171-84.
    • (1996) Technologies for Detection of DNA Damage and Mutations , pp. 171-184
    • Yakes, F.M.1    Chen, Y.2    Van Houten, B.3
  • 19
    • 0035422139 scopus 로고    scopus 로고
    • Inhibition of glioma growth in vivo by selective activation of CB2 cannabinoid receptor
    • Sanchez C, de Ceballos ML, Gomez del Pulgar T, et al. Inhibition of glioma growth in vivo by selective activation of CB2 cannabinoid receptor. Cancer Res 2001;61:5784-9.
    • (2001) Cancer Res , vol.61 , pp. 5784-5789
    • Sanchez, C.1    de Ceballos, M.L.2    Gomez del Pulgar, T.3
  • 20
    • 0032493378 scopus 로고    scopus 로고
    • The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation
    • De Petrocellis L, Melck D, Palmisano A, et al. The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. Proc Natl Acad Sci U S A 1998;95:8375-80.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8375-8380
    • De Petrocellis, L.1    Melck, D.2    Palmisano, A.3
  • 21
    • 0033405883 scopus 로고    scopus 로고
    • Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells
    • Melck D, Rueda D, Galve-Roperh I, De Petrocellis L, Guzman M, Di Marzo V. Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. FEBS Lett 1999;463: 235-40.
    • (1999) FEBS Lett , vol.463 , pp. 235-240
    • Melck, D.1    Rueda, D.2    Galve-Roperh, I.3    De Petrocellis, L.4    Guzman, M.5    Di Marzo, V.6
  • 22
    • 0002117840 scopus 로고
    • DT-diaphorase, a historical review
    • Ernster L. DT-diaphorase, a historical review. Chem Scripta 1987;27: 1-13.
    • (1987) Chem Scripta , vol.27 , pp. 1-13
    • Ernster, L.1
  • 23
    • 0020464384 scopus 로고
    • DT-diaphorase as a quinone reductase: A cellular control device against serniquinone and superoxide radical formation
    • Lind C, Hochstein P, Ernster L. DT-diaphorase as a quinone reductase: a cellular control device against serniquinone and superoxide radical formation. Arch Biochem Biophys 1992;216:178-85.
    • (1992) Arch Biochem Biophys , vol.216 , pp. 178-185
    • Lind, C.1    Hochstein, P.2    Ernster, L.3
  • 24
    • 0032571361 scopus 로고    scopus 로고
    • Disruption of the DT-diaphorase (NQO1) gene in mice leads to increased menadione toxicity
    • Radjendirane V, Joseph P, Lee YH, et al. Disruption of the DT-diaphorase (NQO1) gene in mice leads to increased menadione toxicity. J Biol Chem 1998;273:7382-9.
    • (1998) J Biol Chem , vol.273 , pp. 7382-7389
    • Radjendirane, V.1    Joseph, P.2    Lee, Y.H.3
  • 25
    • 13444273546 scopus 로고    scopus 로고
    • DNA repair: The importance of phosphorylating histone H2AX
    • Lowndes NF, Toh GW. DNA repair: the importance of phosphorylating histone H2AX. Curr Biol 2005; 15:1399-402.
    • (2005) Curr Biol , vol.15 , pp. 1399-1402
    • Lowndes, N.F.1    Toh, G.W.2
  • 27
    • 0000191348 scopus 로고    scopus 로고
    • DNA Topoisomerase II rescue by catalytic inhibitors
    • Jensen PB, Sehestedf M. DNA Topoisomerase II rescue by catalytic inhibitors. Biochem Pharmacol 1997;54:755-9.
    • (1997) Biochem Pharmacol , vol.54 , pp. 755-759
    • Jensen, P.B.1    Sehestedf, M.2
  • 28
    • 0030877010 scopus 로고    scopus 로고
    • Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents
    • Wang HK, Morris-Natschke SL, Lee KS. Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents. Med Res Rev 1997;17:367-425.
    • (1997) Med Res Rev , vol.17 , pp. 367-425
    • Wang, H.K.1    Morris-Natschke, S.L.2    Lee, K.S.3
  • 30
    • 24944465781 scopus 로고    scopus 로고
    • Cannabinoids and cancer
    • Kogan NM. Cannabinoids and cancer. Mini Rev Med Chem 2005;5: 941-52.
    • (2005) Mini Rev Med Chem , vol.5 , pp. 941-952
    • Kogan, N.M.1
  • 31
    • 33745250125 scopus 로고    scopus 로고
    • A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells
    • Kogan NM, Blázquez C, Álvarez L, et al. A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells. Mol Pharmacol 2006;70:51-9.
    • (2006) Mol Pharmacol , vol.70 , pp. 51-59
    • Kogan, N.M.1    Blázquez, C.2    Álvarez, L.3
  • 33
    • 3543092021 scopus 로고    scopus 로고
    • Pathways of apoptotic and non-apoptotic death in tumor cells
    • Okada H, Mak TW. Pathways of apoptotic and non-apoptotic death in tumor cells. Nat Rev Cancer 2004;4:592-603.
    • (2004) Nat Rev Cancer , vol.4 , pp. 592-603
    • Okada, H.1    Mak, T.W.2
  • 34
    • 5044249067 scopus 로고    scopus 로고
    • Paraptosis: Mediation by MAP kinases and inhibition by AIP-1/Alix
    • Sperandio S, Poksay K, de Belle I, et al. Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix. Cell Death Differ 2004;11:1066-75.
    • (2004) Cell Death Differ , vol.11 , pp. 1066-1075
    • Sperandio, S.1    Poksay, K.2    de Belle, I.3
  • 35
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: Dual roles in life and death?
    • Baehrecke EH. Autophagy: dual roles in life and death? Nat Mol Cell Biol 2005;6:505-10.
    • (2005) Nat Mol Cell Biol , vol.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 38
    • 2642536197 scopus 로고    scopus 로고
    • Alkylating DNA damage stimulates a regulated form of necrotic cell death
    • Zong WX, Distrworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004; 18:1272-82.
    • (2004) Genes Dev , vol.18 , pp. 1272-1282
    • Zong, W.X.1    Distrworth, D.2    Bauer, D.E.3    Wang, Z.Q.4    Thompson, C.B.5
  • 39
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: From caspases to alternative mechanisms
    • Leist M, Jaatela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001;2:589-98.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 589-598
    • Leist, M.1    Jaatela, M.2
  • 40
    • 0033045065 scopus 로고    scopus 로고
    • Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by beta-lapachone in human carcinoma cells
    • Li YZ, Li CJ, Pinto AV, Pardee AB. Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by beta-lapachone in human carcinoma cells. Mol Med 1999;5:232-9.
    • (1999) Mol Med , vol.5 , pp. 232-239
    • Li, Y.Z.1    Li, C.J.2    Pinto, A.V.3    Pardee, A.B.4
  • 41
    • 0022504993 scopus 로고
    • Antitumor agents. 78. Inhibition of human DNA topoisomerase II by podophyllotoxin and alpha-peltatin analogues
    • Thurston LS, Irie H, Tani S, et al. Antitumor agents. 78. Inhibition of human DNA topoisomerase II by podophyllotoxin and alpha-peltatin analogues. J Med Chem 1986;29:1547-50.
    • (1986) J Med Chem , vol.29 , pp. 1547-1550
    • Thurston, L.S.1    Irie, H.2    Tani, S.3
  • 42
    • 0027323945 scopus 로고
    • Stereo (C7)-dependent topoisomerase II inhibition and tumor growth suppression by a new quinolone, BO-2367
    • Yoshinari T, Mano E, Arakawa H, et al. Stereo (C7)-dependent topoisomerase II inhibition and tumor growth suppression by a new quinolone, BO-2367. Jpn J Cancer Res 1993;84:800-6.
    • (1993) Jpn J Cancer Res , vol.84 , pp. 800-806
    • Yoshinari, T.1    Mano, E.2    Arakawa, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.