Cocaine-induced genital reflexes in paradoxical sleep deprived rats: Indications of mediation by serotonin receptors

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 31, Issue 2, 2007, Pages 496-502

  Andersen, Monica L ^a   Antunes, Isabela B ^a   Tufik, Sergio ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

cocaine; DOI; DPAT; ketanserin; pindolol; serotonin receptors; sexual behavior; sleep deprivation

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; BUSPIRONE; COCAINE; IPSAPIRONE; KETANSERIN; PINDOLOL; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; EJACULATION; LATENT PERIOD; MALE; NONHUMAN; PENIS ERECTION; RAT; RECEPTOR INTRINSIC ACTIVITY; REM SLEEP DEPRIVATION; SEROTONINERGIC SYSTEM; SEXUAL BEHAVIOR;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; DOPAMINE UPTAKE INHIBITORS; DRUG INTERACTIONS; MALE; PENILE ERECTION; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SLEEP DEPRIVATION; SLEEP, REM;

EID: 33846815088     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2006.11.018     Document Type: Article

References (41)

1. Ahlenius S., and Larsson K. New aspects on the serotonergic modulation of male rat sexual behavior. In: Bevan P., Cools A.R., and Archer T. (Eds). Behav Pharmacol of serotonin (1989), Lawrence Erlbaum, Hillsdale 35
2. Ahlenius S., and Larsson K. Evidence for an involvement of 5-HT1B receptors in the inhibition of male rat ejaculatory behavior produced by 5-HTP. Psychopharmacology 137 (1998) 374-382
3. Ahlenius S., Larsson K., Svensson L., Hjorth S., Carlsson A., Lindberg P., et al. Effects of a new type of 5-HT receptor agonist on male rat sexual behavior. Pharmacol Biochem Behav 15 (1981) 785-792
4. Amalric M., and Koob G.F. Functionally selective neurochemical afferents and efferents of the mesocorticolimbic and nigrostriatal dopamine system. In: Arbthnott G.W., and Emson P.C. (Eds). Progress in Brain Res (1993), Elsevier Science, New York 209-226
5. Andersen M.L., and Tufik S. Inhibitory effect of GABAergic drugs in cocaine-induced genital reflexes in paradoxical sleep deprived male rats. Pharmacol Biochem Behav 78 (2004) 301-307
6. Andersen M.L., Bignotto M., and Tufik S. Cocaine-induced genital reflexes during paradoxical sleep deprivation and recovery. Physiol Behav 78 (2003) 255-259
7. Andersen M.L., Bignotto M., Papale L.A., and Tufik S. Age-related effects of genital reflexes induced by paradoxical sleep deprivation and cocaine in rats. Exp Gerontol 39 (2004) 233-237
8. Andersen M.L., Antunes I.B., and Tufik S. Noradrenergic system interacts with genital reflexes-induced by cocaine in paradoxical sleep deprived male rats. Behav Neurosci 119 (2005) 473-482
9. Andersen M.L., Papale L.A., Hipolide D.C., Nobrega J., and Tufik S. Involvement of dopamine receptors in cocaine-induced genital reflexes after paradoxical sleep deprivation. Behav Brain Res 160 (2005) 44-50
10. Andersson K.E. Pharmacology of penile erection. Pharmacol Rev 53 (2001) 417-450
11. Barnes N.M., and Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 38 (1999) 1083-1152
12. Berendsen H.H.G., and Broekkamp C.L.E. Drug-induced penile erections in rats: indications of serotonin 1B receptor mediation. Eur J Pharmacol 135 (1987) 279-287
13. Everitt B.J. Sexual motivation: a neural and behavioral analysis of the mechanisms underlying appetitive and copulatory responses of male rats. Neurosci Biobehav Rev 14 (1990) 217-232
14. Farooqui S.M., Brock J.W., and Zhou J. Changes in monoamines and their metabolite concentrations in REM sleep-deprived rat forebrain nuclei. Pharmacol Biochem Behav 54 (1996) 385-391
15. Faure C., Mnie-Filali O., Scarna H., Debonnel G., and Haddjeri N. Effects of the 5-HT7 receptor antagonist SB-269970 on rat hormonal and temperature responses to the 5-HT1A/7 receptor agonist 8-OH-DPAT. Neurosci Lett 404 (2006) 122-126
16. Fernandez-Guasti A., Escalante A., and Agmo A. Inhibitory action of various 5-HT1B receptor agonists on rat masculine sexual behavior. Pharmacol Biochem Behav 34 (1989) 811-816
17. Foreman M.M., Hall J.L., and Love R.L. The role of the 5-HT2 receptor in the regulation of sexual performance of male rats. Life Sci 45 (1989) 1263-1270
18. Glennon R.A. Serotonin receptors: clinical implications. Neurosci Biobehav Rev 14 (1990) 35-47
19. Gorzalka B.B., Mendelson S.D., and Watson N.V. Serotonin receptor subtypes and sexual behavior. Ann NY Acad Sci 600 (1990) 435-446
20. Gorzalka B.B., Hanson L.A., and Hong J.J. Ketanserin attenuates the behavioural effects of corticosterone: implications for 5-HT2a receptor regulation. Eur J Pharmacol 428 (2001) 235-240
21. Herges S., and Taylor D.A. Modulatory effect of p-chlorophenylalanine microinjected into the dorsal and median raphe nuclei on cocaine-induced behaviour in the rat. Eur J Pharmacol 374 (1999) 329-340
22. Hipolide D.C., Nobrega J.N., and Tufik S. Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain. Prog Neuro-Psychopharmacol Biol Psychiatry 29 (2005) 297-303
23. Kelland M.D., Freeman A.S., Rubin J., and Chiodo L.A. Ascending afferent regulation of rat midbrain dopaminergic neurons. Brain Res Bull 31 (1993) 539-546
24. 2 antagonist amperozide attenuates 1-2,5-dimethoxy-4-iodophenyl)-2-aminopropane-induced inhibition of male rat sexual behavior. Eur J Pharmacol 212 (1992) 241-246
25. Koe B.K. Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain. J Pharmacol Exp Ther 199 (1976) 649-661
26. Malmnas C.O., and Meyerson B.J. P-chlorophenylalamine and copulatory behavior in the male rat. Nature 232 (1971) 398-400
27. Mathes C.W., Smith E.R., Popa B.R., and Davidson J.M. Effects of intrathecal and systemic administration of buspirone on genital reflexes and mating behavior in male rats. Pharmacol Biochem Behav 36 (1990) 63-68
28. 4 receptors in the nucleus accumbens shell. J Pharmacol Exp Ther 291 (1999) 300-307
29. McMahon L.R., and Cunningham K.A. Antagonism of 5-hydroxytryptamine 2A receptors attenuates the behavioral effects of cocaine in rats. J Pharmacol Exp Ther 297 (2001) 357-363
30. Mendelson S.D., and Gorzalka B.B. Serotonin antagonist pirenperone inhibits sexual behavior in the male rat: attenuation by quipazine. Pharmacol Biochem Behav 22 (1985) 565-571
31. Morali G., and Larsson K. Differential effects of a new seroninomimetic drug, 8-OH-DPAT, on copulatory behavior and pelvic thrusting pattern in the male rat. Pharmacol Biochem Behav 20 (1984) 185-187
32. A-receptor antagonism blocks behavioural but potentiates serotonergic activation. Synapse 45 (2002) 67-77
33. Parsons L.H., and Justice J.B. Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis. Brain Res 606 (1993) 195-199
34. Peltier R.L., Emmett-Oglesby M.W., Thomas W.H., and Schenk S. Failure of ritanserin to block the discrimative or reinforcing stimulus effects of cocaine. Pharmacol Biochem Behav 48 (1994) 473-478
35. Pradhan S.N., Battacharyya A.K., and Pradhan S. Serotonergic manipulation of the behavioral effects of cocaine in rats. Commun Psychopharmacol 2 (1978) 481-486
36. Scheel-Kruger J., Braestrup C., Nielson M., Golembiowska K., and Moglinicka E. Cocaine: discussion on the role of dopamine in the biochemical mechanism of action. In: Ellinwood E.H., and Kilbey M.M. (Eds). Cocaine and other stimulants (1977), Plenum Press, New York 373-407
37. Tricklebank M.D., Forler C., Middlemiss D.N., and Fozard J.R. Subtypes of the 5-HT receptor mediating the behavioral responses to 5-methoxy-N-N-dimethyltryptamine in the rat. Eur J Pharmacol 117 (1985) 15-24
38. Tufik S., Lindsey C.J., and Carlini E.A. Does REM sleep deprivation induce a supersensitivity of dopaminergic receptors in the rat brain?. Pharmacology 6 (1978) 95-108
39. Walsh S.L., and Cunningham K.A. Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine. Psychopharmacology 130 (1997) 41-58
40. Watson N.V., and Gorzalka B.B. DOI-induced inhibition of copulatory behavior in male rats: reversal by 5-HT 2 antagonists. Pharmacol Biochem Behav 39 (1991) 605-612
41. Wise R.A. Drug-activation of brain pathways. Drug Alcohol Depend 51 (1998) 13-22