Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 50, 2006, Pages 18917-18922

  Hagemeier, Christoph H ^a   Krüer, Markus ^a   Thauer, Rudolf K ^a   Warkentin, Eberhard ^b   Ermler, Ulrich ^b  

^a MAX PLANCK INSTITUTE FOR TERRESTRIAL MICROBIOLOGY   (Germany)

^b MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

Author keywords

Conformational change; Methanol metabolism; X ray structure; Zinc

Indexed keywords

CARBON; COBALAMIN; METHANOL; METHYLTRANSFERASE; OXYGEN; ZINC; CYANOCOBALAMIN; METHANOL 2 MERCAPTOETHANESULFONIC ACID METHYLTRANSFERASE; METHANOL-2-MERCAPTOETHANESULFONIC ACID METHYLTRANSFERASE;

ALCOHOL METABOLISM; ARTICLE; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; METHANOSARCINA BARKERI; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

METHANOSARCINA BARKERI;

BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; METHANOL; METHANOSARCINA BARKERI; METHYLTRANSFERASES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; VITAMIN B 12; ZINC;

EID: 33846809521     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0603650103     Document Type: Article

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