Involvement of transglutaminase-2 in pathological changes in renal disease

Nephron - Clinical Practice

Volumn 105, Issue 3, 2007, Pages

  Ikee, Ryota ^a,b   Kobayashi, Shuzo ^b   Hemmi, Noriaki ^a   Saigusa, Takamitsu ^a   Namikoshi, Tamehachi ^a   Yamada, Muneharu ^a   Imakiire, Toshihiko ^a   Kikuchi, Yuichi ^a   Suzuki, Shigenobu ^a   Miura, Soichiro ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b SHONAN KAMAKURA GENERAL HOSPITAL   (Japan)

Author keywords

Crescentic formation; Glomerular sclerosis; Transglutaminase 2; Tubulointerstitial injury; Vascular pole

Indexed keywords

BETA 2 MICROGLOBULIN; CREATININE; N ACETYL BETA GLUCOSAMINIDASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TRANSFORMING GROWTH FACTOR BETA; TRANSGLUTAMINASE 2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BETA 2 MICROGLOBULIN URINE LEVEL; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; FEMALE; GLOMERULOSCLEROSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY TUBULE DAMAGE; MALE; MEDICAL PARAMETERS; MESANGIUM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL;

ADULT; AGED; FEMALE; GLOMERULONEPHRITIS, IGA; GTP-BINDING PROTEINS; HUMANS; KIDNEY; MALE; MIDDLE AGED; TISSUE DISTRIBUTION; TRANSGLUTAMINASES;

EID: 33846807323     PISSN: 16602110     EISSN: None     Source Type: Journal    
DOI: 10.1159/000098646     Document Type: Article

References (31)

1. Griffin M, Casadio R, Bergamini CM: Transglutaminase: nature's glues. Biochem J 2002;368:377-396.
2. Fesus L, Piacentini M: Transglutaminase-2: an enigmatic enzyme with diverse functions. Trends Biochem Sci 2002;27:534-539.
3. Thomazy V, Fesus L: Differential expression of transglutaminase in human cells: an immunohistochemical study. Cell Tissue Res 1989;255:215-224.
4. Hirschberg R, Wang S: Proteinuria and growth factors in the development of tubulointerstitial injury and scarring in kidney disease. Curr Opin Nephrol Hypertens 2005;14:43-52.
5. 1 in normal and transformed human epidermal keratinocytes. J Biol Chem 1990;265:11098-11104.
6. Kojima S, Nara K, Rifkin DB: Requirement for transglutaminase in the activation of latent transforming factor-β in bovine endothelial cells. J Cell Biol 1993;121:439-448.
7. Kikuchi Y, Kobayashi S, Hemmi N, et al: Galectin-3-positive cell infiltration in human diabetic nephropathy. Nephrol Dial Transplant 2004;19:602-607.
8. Ophascharoesuk V, Pippin JW, Gordon KL, Shankland SJ, Couser WG, Johnson RJ: Role of intrinsic renal cells versus infiltrating cells in glomerular crescent formation. Kidney Int 1998;54:416-425.
9. Wada T, Hamakawa S, Hori Y, et al: Immunohistochemical localization of latent transforming growth factor-β binding protein in IgA nephropathy. Kidney Int 1997;52(suppl 63):S182-S184.
10. Kliem V, Johnson RJ, Alpers CE, et al: Mechanisms involved in the pathogenesis of interstitial fibrosis in 5/6-nephrectomaized rats. Kidney Int 1996;49:666-678.
11. Johnson TS, El-Koraie AF, Skill NJ, et al: Tissue transglutaminase and the progression of human renal scarring. J Am Soc Nephrol 2003;14:2052-2062.
12. Skill NJ, Johnson TS, Coutts IG, et al: Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells. J Biol Chem 2004;279:47754-47762.
13. 1 on renal extracellular matrix components and their regulating proteins. J Am Soc Nephrol 1999;10:2109-2119.
14. Howie AJ, Kizaki T, Beaman M, et al: Different types of segmental sclerosing glomerular lesions in six experimental models of proteinuria. J Pathol 1989;157:141-151.
15. Kriz W, Hosser H, Hahnel B, Simons JL, Provoost AP: Development of vascular pole-associated glomerulosclerosis in the Fawn-hooded rat. J Am Soc Nephrol 1998;9:381-396.
16. Harvey JM, Howie AJ, Lee SJ, et al: Renal biopsy findings in hypertensive patients with proteinuria. Lancet 1992;340:1435-1436.
17. Howie AJ: Benign essential hypertension and kidney damage: a histopathologist's view. J Hum Hypertens 1996;10:691-694.
18. Osterby R, Asplund J, Bangstad HJ, et al: Glomerular volume and the vascular pole area in patients with insulin-dependent diabetes mellitus. Virchows Arch 1997;431:351-357.
19. Howie AJ: Pathology of minimal change nephropathy and segmental sclerosing glomerular disorders. Nephrol Dial Transplant 2003;18(suppl 6):vi33-vi38.
20. Bowness JM, Folk JE, Timpl R: Identification of a substrate site for liver transglutaminase on the aminopropeptide of type III collagen. J Biol Chem 1987;262:1022-1024.
21. Razzaque MS, Koji T, Taguchi T, Harada T, Nakane PK: In situ localization of type III and type IV collagen-expressing cells in human diabetic nephropathy. J Pathol 1994;174:131-138.
22. Yoshioka K, Takemura T, Tohda M, et al: Glomerular localization of type III collagen in human kidney disease. Kidney Int 1989;35:1203-1211.
23. Lee LK, Meyer TW, Pollock AS, Lovett DH: Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney. J Clin Invest 1995;96:953-964.
24. Le Hir M, Keller C, Eschmann V, Hahnel B, Hosser H, Kriz W: Podocyte bridges between the tuft and Bowman's capsule: an early event in experimental crescentic glomerulonephritis. J Am Soc Nephrol 2001;12:2060-2071.
25. Kanemoto K, Usui J, Tomari S, et al: Connective tissue growth factor participates in scar formation of crescentic glomerulonephritis. Lab Invest 2003;83:1615-1625.
26. Ng YY, Fan JM, Mu W, et al: Glomerular epithelial-myofibroblast transdifferentiation in the evolution of glomerular crescent formation. Nephrol Dial Transplant 1999;14:2860-2872.
27. Fujigaki Y, Sun DF, Fujimoto T, et al: Mechanism and kinetics of Bowman's epithelialmyofibroblast transdifferentiation in the formation of glomerular crescents. Nephron 2001;92:203-212.
28. Moeller MJ, Soofi A, Hartmann I, et al: Podocytes populate cellular crescents in a murine model of inflammatory glomerulonephritis. J Am Soc Nephrol 2004;15:61-67.
29. Bariety J, Bruneval P, Meyrier A, Mandet C, Hill G, Jacqout C: Podocyte involvement in human immune crescentic glomerulonephritis. Kidney Int 2005;68:1109-1119.
30. Garcia GE, Xia Y, Harrison J, et al: Mononuclear cell-infiltrate inhibition by blocking macrophage-derived chemokine results in attenuation of developing crescentic glomerulonephritis. Am J Physiol 2003;162:1061-1073.
31. Isome M, Fujinaka H, Adhikary LP, et al: Important role for macrophages in induction of crescentic anti-GBM glomerulonephritis in WKY rats. Nephrol Dial Transplant 2004;19:2997-3004.