Glomerular volume and the glomerular vascular pole area in patients with insulin-dependent diabetes mellitus

Virchows Archiv

Volumn 431, Issue 5, 1997, Pages 351-357

  Østerby, Ruth ^a   Asplund, Johan ^b   Bangstad, Hans Jacob ^c   Nyberg, Gudrun ^d   Rudberg, Susanne ^e   Viberti, GianCarlo ^f   Walker, James D ^f  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b FALUN HOSPITAL   (Sweden)

^c AKER UNIVERSITY HOSPITAL   (Norway)

^d SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^e KAROLINSKA INSTITUTE   (Sweden)

^f GUY S HOSPITAL   (United Kingdom)

Author keywords

Diabetic glomerulopathy; Glomerular hypertrophy; Glomerular vascular pole; Insulin dependent diabetes mellitus (IDDM); Stereology

Indexed keywords

ALBUMIN;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; FEMALE; GLOMERULUS; HUMAN; HUMAN TISSUE; HYPERTROPHY; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY BIOPSY; KIDNEY DONOR; LIVING DONOR; MALE; PRIORITY JOURNAL; URINARY EXCRETION;

ADOLESCENT; ADULT; BIOPSY; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; FEMALE; HUMANS; HYPERTROPHY; KIDNEY GLOMERULUS; MALE; MIDDLE AGED;

EID: 0030700558     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050110     Document Type: Article

References (26)

1. Bangstad H-J, Østerby R, Dahl-Jørgensen K, Berg KJ, Hartmann A, Nyberg G, Bjørn SF, Hanssen KF (1993) Early glomerulopathy is present in young, type 1 (insulin-dependent) diabetic patients with microalbuminuria. Diabetologia 36:523-529
2. Bilous RW, Mauer SM, Sutherland DE, Steffes MW (1989) Mean glomerular volume and rate of development of diabetic nephropathy. Diabetes 38:1142-1147
3. Brenner BM, Lawler EV, Mackenzie HS (1996) The hyperfiltration theory: a paradigm shift in nephroloey. Kidney Int 49:1774-1777
4. Christiansen JS, Gammelgaard J, Frandsen M, Parving H-H (1981) Increased kidney size, glomerular filtration rate and renal plasma flow in short-term insulin-dependent diabetics. Diabetologia 20:451-456
5. Elias H, Henning A (1967) Stereology of the human renal glomerulus. In: Weibel ER, Elias H (eds) Quantitative methods in morphology. Springer, Berlin Heidelberg New York, pp 130-166
6. Flyvbjerg A (1993) The role of insulin-like growth factor 1 in initial renal hypertrophy in experimental diabetes. In: Flyvbierg A, Ørskov H, Alberti KGMM (eds) Growth hormone and insulin-like growth factor 1. Wiley, New York London Sydney, pp 271-306
7. Gøtzsche O, Gundersen HJ, Østerby R (1981) Irreversibility of glomerular basement membrane accumulation despite reversibility of renal hypertrophy with islet transplantation in early experimental diabetes. Diabetes 30:481-485
8. Gulmann C, Østerby R, Rudberg S, Asplund J, Nyberg G (1996) Enlargement of the juxtaglomerular apparatus in IDDM patients with microalbuminuria (abstract). Eur J Endocrinol 134 [Suppl 1]:11-11
9. Gundersen HJ, Østerby R (1977) Glomerular size and structure in diabetes mellitus. II. Late abnormalities. Diabetologia 13:43-48
10. Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Moøller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sørensen FB, Vesterby A (1988) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96:379-394
11. Hirose K, Tsuchida H, Østerby R, Gundersen HJ (1980) A strong correlation between glomerular filtration rate and filtration surface in diabetic kidney hyperfunction. Lab Invest 43:434-437
12. Hirose K, Østerby R, Nozawa M, Gundersen HJ (1982) Development of glomerular lesions in experimental long-term diabetes in the rat. Kidney Int 21:889-895
13. Lane PH, Steffes MW, Mauer SM (1992) Estimation of glomerular volume: a comparison of four methods. Kidney Int 41:1085-1089
14. Mogensen CE (1989) Hyperfiltration, hypertension, and diabetic nephropathy in IDDM patients. Diabetes Nutr Metab 2:227-244
15. Mogensen CE, Østerby R, Gundersen HJ (1979) Early functional and morphologic vascular renal consequences of the diabetic state. Diabetologia 17:71-76
16. Nyengaard JR, Rasch R (1993) The impact of experimental diabetes mellitus in rats on glomerular capillary number and sizes. Diabetologia 36:189-194
17. Østerby R (1995) Research methodologies related to renal complications: structural changes. In: Mogensen CE, Standl E (eds) Research methodologies in human diabetes, vol. 2. Diabetes forum series, V II. de Gruyter, Berlin New York, pp 289-309
18. Østerby R, Gundersen HJ (1975) Glomerular size and structure in diabetes mellitus. I. Early abnormalities. Diabetologia 11:225-229
19. Østerby R, Parving H-H, Nyberg G, Hommel E, Jørgensen HE, Løkkegaard H, Svalander C (1988) A strong correlation between glomerular filtration rate and filtration surface in diabetic nephropathy. Diabetologia 31:265-270
20. Østerby R, Parving H-H, Hommel E, Jørgensen HE, Løkkegaard H (1990) Glomerular structure and function in diabetic nephropathy. Early to advanced stages. Diabetes 39:1057-1063
21. Rudberg S, Østerby R (1997) Decreasing glomerular filtration rate - an indicator of more advanced diabetic glomerulopathy in the early course of microalbuminuria in IDDM adolescents? Nephrol Dial Transplant 12:1149-1154
22. Rudberg S, Østerby R, Dahlquist G, Nyberg G, Persson B (1997) Predictors of renal morphological changes in the early stage of microalbuminuria in adolescents with IDDM. Diabetes Care 20:265-271
23. Seyer-Hansen K, Hansen J, Gundersen HJ (1980) Renal hypertrophy in experimental diabetes. A morphometric study. Diabetologia 18:501-505
24. Teppo AM (1982) Immunoturbidimetry of albumin and globulin in urine. Clin Chem 28:1359-1361
25. Walker JD, Close CF, Jones SL, Rafftery M, Keen H, Viberti GC, Østerby R (1992) Glomerular structure in type-1 (insulin-dependent) diabetic patients with normo- and microalbuminuria. Kidney Int 41:741-748
26. Zatz R, Fujihara CK (1994) Glomerular hypertrophy and progressive glomerulopathy. Is there a definite pathogenetic correlation? Kidney Int Suppl 45:S27-S29