Cost-effectiveness analysis of treatment options for acute otitis media

Annals of Family Medicine

Volumn 5, Issue 1, 2007, Pages 29-38

  Coco, Andrew S ^a  

^a LANCASTER GENERAL HOSPITAL   (United States)

Author keywords

Acute otitis media; Antibiotics; Children; Cost effectiveness analysis; Decision analysis; Disease management; Health care use; Watchful waiting

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; CEFTRIAXONE;

ACUTE OTITIS MEDIA; ANTIBIOTIC THERAPY; ARTICLE; COST EFFECTIVENESS ANALYSIS; DRUG COST; DRUG EFFICACY; DRUG SENSITIVITY; GASTROINTESTINAL DISEASE; HUMAN; MASTOIDITIS; NETHERLANDS; PRESCRIPTION; PRIMARY MEDICAL CARE; QUALITY ADJUSTED LIFE YEAR; RASH;

ACUTE DISEASE; AMOXICILLIN; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; COST OF ILLNESS; COST-BENEFIT ANALYSIS; DECISION SUPPORT TECHNIQUES; HUMANS; INFANT; NETHERLANDS; OTITIS MEDIA; QUALITY-ADJUSTED LIFE YEARS; UNITED STATES;

EID: 33846695153     PISSN: 15441709     EISSN: 15441717     Source Type: Journal    
DOI: 10.1370/afm.626     Document Type: Article

References (62)

1. Centers for Disease Control and Prevention. NAMCS, National Ambulatory Medical Care Survey. Available at: http://www.cdc.gov/nchs/about/major/ahcd/ surinst.htm#Survey%20Instrument%20 NAMCS.
2. Takata G, Chan L, Ernst R, Shekelle P, Marcy S. Management of Acute Otitis Media. Evidence Report/Technology Assessment No. 15. Rockville, MD: Agency for Health Care Policy and Research, Public Health Service, US Department of Health and Human Services; AHRQ Publication No. 01-E010.
3. McCaig LF, Hughes JM. Trends in antimicrobial drug prescribing among office-based physicians in the United States. JAMA. 1995;273(3):214-219.
4. Paradise JL, Rockette HE, Colborn DK, et al. Otitis media in 2253 Pittsburgh-area infants: prevalence and risk factors during the first two years of life. Pediatrics. 1997;99(3):318-333.
5. Froom J, Culpepper L, Jacobs M, et al. Antimicrobials for acute otitis media? A review from the International Primary Care Network. BMJ. 1997;315(7100):98-102.
6. Culpepper L, Froom J. Routine antimicrobial treatment of acute otitis media: is it necessary? JAMA. 1997;278(20):1643-1645.
7. McConaghy JR, Smith SR. Controversy in otitis media management: should we follow the CDC recommendations? Am Fam Physician. 2000;61(2):317-318.
8. Del Mar C, Glasziou P, Hayem M. Are antibiotics indicated as initial treatment for children with acute otitis media? A meta-analysis. BMJ. 1997;314(7093):1526-1529.
9. Glasziou PP, Hayem M, Del Mar CB. Antibiotics for acute otitis media in children. Cochrane Database Syst Rev. 2000;(2):CD000219.
10. Takata GS, Chan LS, Shekelle P, et al. Evidence assessment of management of acute otitis media: I. The role of antibiotics in treatment of uncomplicated acute otitis media. Pediatrics. 2001;108(2): 239-247.
11. Rosenfeld RM, Vertrees JE, Carr J, et al. Clinical efficacy of antimicrobial drugs for acute otitis media: metaanalysis of 5400 children from thirty-three randomized trials. J Pediatr. 1994;124(3):355-367.
12. Chan LS, Takata GS, Shekelle P, et al. Evidence assessment of management of acute otitis media: II. Research gaps and priorities for future research. Pediatrics. 2001;108(2):248-254.
13. van Buchem FL, Peeters MF, van 't Hof MA. Acute otitis media: a new treatment strategy. Br Med J (Clin Res Ed). 1985;290(6474):1033-1037.
14. Dowell SF, Schwartz B. Resistant pneumococci: protecting patients through judicious use of antibiotics. Am Fam Physician. 1997;55(5): 1647-1654, 1657-1658.
15. Block SL, Harrison CJ, Hedrick JA, et al. Penicillin-resistant Streptococcus pneumoniae in acute otitis media: risk factors, susceptibility patterns and antimicrobial management. Pediatr Infect Dis J. 1995;14(9):751-759.
16. Reichler MR, Allphin AA, Breiman RF, et al. The spread of multiply resistant Streptococcus pneumoniae at a day care center in Ohio. J Infect Dis. 1992;166(6):1346-1353.
17. Arason VA, Kristinsson KG, Sigurdsson JA, et al. Do antimicrobials increase the carriage rate of penicillin resistant pneumococci in children? Cross sectional prevalence study. BMJ. 1996;313(7054): 387-391.
18. Stephenson J. Icelandic researchers are showing the way to bring down rates of antibiotic-resistant bacteria. JAMA. 1996;275(3):175.
19. Whitney CG, Farley MM, Hadler J, et al. Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States. N Engl J Med. 2000;343(26):1917-1924.
20. Schwartz B, Bell DM, Hughes JM. Preventing the emergence of antimicrobial resistance. A call for action by clinicians, public health officials, and patients. JAMA. 1997;278(11):944-945.
21. Little P, Gould C, Williamson I, et al. Pragmatic randomised controlled trial of two prescribing strategies for childhood acute otitis media. BMJ. 2001;322(7282):336-342.
22. Siegel RM, Kiely M, Bien JP, et al. Treatment of otitis media with observation and a safety-net antibiotic prescription. Pediatrics. 2003;112(3 Pt 1):527-531.
23. McCormick DP, Chonmaitree T, Pittman C, et al. Nonsevere acute otitis media: a clinical trial comparing outcomes of watchful waiting versus immediate antibiotic treatment. Pediatrics. 2005;115(6): 1455-1465.
24. Marchetti F, Ronfani L, Nibali SC, Tamburlini G. Delayed prescription may reduce the use of antibiotics for acute otitis media: a prospective observational study in primary care. Arch Pediatr Adolesc Med. 2005;159(7):679-684.
25. American Academy of Pediatrics Subcommittee on Management of Acute Otitis Media. Diagnosis and management of acute otitis media. Pediatrics. 2004;113(5):1451-1465.
26. Appelman C, Bossen P, Dunk J, et al. Nederlands Huisarts en Genootschap standaard Otitis Media Acuta. Huisarts Wet. 1990;33:242-245.
27. Froom J, Culpepper L, Green LA, et al. A cross-national study of acute otitis media: risk factors, severity, and treatment at initial visit. Report from the International Primary Care Network (IPCN) and the Ambulatory Sentinel Practice Network (ASPN). J Am Board Fam Pract. 2001;14(6):406-417.
28. Kaleida PH, Casselbrant ML, Rockette HE, et al. Amoxicillin or myringotomy or both for acute otitis media: results of a randomized clinical trial. Pediatrics. 1991;87(4):466-474.
29. Kozyrskyj AL, Hildes-Ripstein GE, Longstaffe SE, et al. Treatment of acute otitis media with a shortened course of antibiotics: a meta-analysis. JAMA. 1998;279(21):1736-1742.
30. Burke P, Bain J, Robinson D, Dunleavey J. Acute red ear in children: controlled trial of non-antibiotic treatment in general practice. BMJ. 1991;303(6802):558-562.
31. Damoiseaux RA, van Balen FA, Hoes AW, Verheij TJ, de Melker RA. Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. BMJ. 2000;320(7231):350-354.
32. Ruben R. Sequelae of antibiotic therapy. In: Rosenfeld R, Bluestone C, eds. Evidence-Based Otitis Media. Hamilton, Ontario: BC Decker Inc; 1999:303-314.
33. Van Zuijlen DA, Schilder AG, Van Balen FA, Hoes AW. National differences in incidence of acute mastoiditis: relationship to prescribing patterns of antibiotics for acute otitis media? Pediatr Infect Dis J. 2001;20(2):140-144.
34. Hamill PV, Drizd TA, Johnson CL, et al. Physical growth: National Center for Health Statistics percentiles. Am J Clin Nutr. 1979;32(3): 607-629.
35. Staff ME, ed. Drug Topics: 2001 Red Book. Oradell, NJ: Medical Economics Company; 2002.
36. Pennsylvania Department of Public Welfare. Office of Medical Assistance Programs Web site. Available at: http://www.dpw.state.pa.us/omap/dpwomap.asp. Accessed April 2003.
37. Briggs AH. Handling uncertainty in cost-effectiveness models. Pharmacoeconomics. 2000;17(5):479-500.
38. Callahan CW Jr. Cost effectiveness of antibiotic therapy for otitis media in a military pediatric clinic. Pediatr Infect Dis J. 1988;7(9): 622-625.
39. Amadasun J. The cost-effective medical treatment of suppurative otitis media in a Nigerian environment. W African J Med. 1997; 16:185-187.
40. Oh PI, Maerov P, Pritchard D, et al. A cost-utility analysis of second-line antibiotics in the treatment of acute otitis media in children. Clin Ther. 1996;18(1):160-182.
41. Luntz M, Brodsky A, Nusem S, et al. Acute mastoiditis - the antibiotic era: a multicenter study. Int J Pediatr Otorhinolaryngol. 2001;57(1):1-9.
42. Harley EH, Sdralis T, Berkowitz RG. Acute mastoiditis in children: a 12-year retrospective study. Otolaryngol Head Neck Surg. 1997; 116(1):26-30.
43. Gliklich RE, Eavey RD, Iannuzzi RA, Camacho AE. A contemporary analysis of acute mastoiditis. Arch Otolaryngol Head Neck Surg. 1996;122(2):135-139.
44. Hoppe JE, Koster S, Bootz F, Niethammer D. Acute mastoiditis - relevant once again. Infection. 1994;22(3):178-182.
45. Centers for Medicare and Medicaid. National Procedures Summary File. Available at: http;/www.cms.hhs.gov/ICD9ProviderDiagnosticCode. Accessed March 2003.
46. Agency for Healthcare Research and Quality. HCUPnet, Healthcare Cost and Utilization Project. Available at: http://hcupnet.ahrq.gov/.
47. Marx J, Hockberger R, Walls R, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 5th ed. Philadelphia, Pa: Elsevier Science; 2002.
48. Capra AM, Lieu TA, Black SB, et al. Costs of otitis media in a managed care population. Pediatr Infect Dis J. 2000;19(4):354-355.
49. Bureau of Labor Statistics. National Compensation Survey. 2001. Available at: http://www.bls.gov/ncs/home.htm. Accessed March 2003.
50. US Department of Labor, Bureau of Labor Statistics. Consumer Price Indexes. Available at: http://www.bls.gov/cpi/. Accessed March 2003.
51. Little P, Gould C, Williamson I, et al. Reattendance and complications in a randomised trial of prescribing strategies for sore throat: the medicalising effect of prescribing antibiotics. BMJ. 1997;315(7104):350-352.
52. Little P, Rumsby K, Kelly J, et al. Information leafl et and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial. JAMA. 2005;293(24):3029-3035.
53. Bisonni RS, Lawler FH, Pierce L. Recurrent otitis media: a cost-utility analysis of simulated treatment using tympanostomy tubes vs antibiotic prophylaxis. Fam Pract Res J. 1991;11(4):371-378.
54. Alsarraf R, Jung CJ, Perkins J, et al. Measuring the indirect and direct costs of acute otitis media. Arch Otolaryngol Head Neck Surg. 1999;125(1):12-18.
55. Berman S, Roark R, Luckey D. Theoretical cost effectiveness of management options for children with persisting middle ear effusions. Pediatrics. 1994;93(3):353-363.
56. Gates GA. Cost-effectiveness considerations in otitis media treatment. Otolaryngol Head Neck Surg. 1996;114(4):525-530.
57. Kaplan B, Wandstrat TL, Cunningham JR. Overall cost in the treatment of otitis media. Pediatr Infect Dis J. 1997;16(2 Suppl):S9-11.
58. Stool SE, Field MJ. The impact of otitis media. Pediatr Infect Dis J. 1989;8(1 Suppl):S11-14.
59. Branthaver B, Greiner DL, Eichelberger B. Determination of costeffective treatment of acute otitis media from HMO records. Am J Health Syst Pharm. 1997;54(23):2736-2740.
60. Landholt TF, Kotschwar TR. A pharmacoeconomic comparison of amoxicillin/clavulanate and cefpodoxime proxetil in the treatment of acute otitis media. Clin Ther. 1994;16(2):327-333; discussion 271-322.
61. Weiss JC, Melman ST. Cost effectiveness in the choice of antibiotics for the initial treatment of otitis media in children: a decision analysis approach. Pediatr Infect Dis J. 1988;7(1):23-26.
62. Gold M, Siegel G, Russell L, Weinstein M, eds. Cost-Effectiveness in Health and Medicine. New York, NY: Oxford University Press; 1996.