Inhibition of lipid peroxidation by anthocyanins, anthocyanidins and their phenolic degradation products

European Journal of Lipid Science and Technology

Volumn 109, Issue 1, 2007, Pages 66-71

  Brown, Jonathan E ^a   Kelly, Mary F ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Anthocyanidin; Anthocyanin; Copper chelation; Lipid oxidation; Phenolic acid

Indexed keywords

EID: 33846690522     PISSN: 14387697     EISSN: 14389312     Source Type: Journal    
DOI: 10.1002/ejlt.200600166     Document Type: Article

References (29)

1. R. L. Jackman, R. Y. Yada, M. A. Tung, R. A. Speers: Anthocyanins as food colorants - a review. J Food Biochem. 1987, 11, 201-247.
2. P. Bridle, C. F. Timberlake: Anthocyanins as natural food colours - selected aspects. Food Chem. 1997, 58, 103-109.
3. M. Dell'Agli, A. Busciala, E. Bosisio: Vascular effects of wine polyphenols. Cardiovasc Res. 2004, 63, 593-602.
4. L. Pilaczynska-Szczesniak, A. Skarpanska-Steinborn, E. Deskur, P. Basta, M. Horoszkiewicz-Hassan: The influence of chokeberry juice supplementation on the reduction of oxidative stress resulting from an incremental rowing ergometer exercise. Int J Sports Nutr Exerc Metab. 2005, 15, 48-58.
5. M. P. Kahkonen, M. Heinonen: Antioxidant activity of anthocyanins and their aglycons. J Agric Food Chem. 2003, 51, 628-633.
6. J. Kuhnau: The flavonoids. A class of semi-essential food components: Their role in human nutrition. World Rev Nutr Dietet. 1976, 24, 117-191.
7. M. N. Clifford: Anthocyanins - nature, occurrence and dietary burden. J Sci Food Agric. 2000, 80, 1063-1072.
8. C. F. Timberlake: The biological properties of anthocyanins. Nat Assoc Colourers Quart Inf Bull. 1988, 4-15.
9. T. Tsuda, F. Horio, T. Osawa: Absorption and metabolism of cyanidin 3-O-β-glucoside in rats. FEBS Lett. 1999, 449, 179-182.
10. T. Miyazawa, K. Nakagawa, M. Kudo, K. Muraishi, K. Someya: Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside, into rats and humans. J Agric Food Chem. 1999, 47, 1083-1091.
11. K. Keppler, H. U. Humpf: Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora. Bioorg Medic Chem. 2005, 13, 5195-5205.
12. A. M. Aura, M. Marin-Lopez, K. A. O'Leary, G. Williamson, K. M. Oksman-Caldentey, K. Poutanen, C. Satos-Buegla: In vitro metabolism of anthocyanins by gut microflora. Eur J Nutr. 2005, 44, 133-142.
13. N. P. Seeram, L. D. Bourquin, M. G. Nair: Degradation products of cyanidin glycosides from tart cherries and their bioactivities. J Agric Food Chem. 2001, 49, 4924-4929.
14. M. Abd El Mohsen, J. Marks, G. Kuhnle, K. Moore, E. Debnam, K. S. Srai, C. Rice-Evans, J. P. E. Spencer: Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats. Br J Nutr. 2006, 95, 51-58.
15. C. D. Kay, G. Mazza, B. J. Holub, J. Wang: Anthocyanin metabolites in human urine and serum. Br J Nutr. 2004, 91, 933-942.
16. G. Cao, H. U. Muccitelli, C. Sanchez-Moreno, R. L. Prior: Anthocyanins are absorbed in glycated forms in elderly women: A pharmacokinetic study. Am J Clin Nutr. 2001, 73, 920-926.
17. B. H. Chung, T. Wilkinson, J. C. Geer, J. P. Segrest: Preparative and quantitative isolation of plasma lipoproteins: Rapid, single discontinuous density gradient ultra-centrifugation in a vertical rotor. J Lipid Res. 1980, 21, 284-291.
18. M. A. Markwell, S. M. Haas, N. E. Tolbert, L. L. Bieber: Protein determination in membrane and lipoprotein samples: Manual and automated procedures. Meth Enzymol. 1981, 72, 296-303.
19. H. Esterbauer, J. Gebicki, H. Puhl, G. Jurgens: The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med. 1992, 13, 341-390.
20. 2+ ions: Implications for their antioxidant properties. Biochem J. 1998, 330, 1173-1178.
21. S. J. Duthie, A. M. Jenkinson, A. Crozier, A. Mullen, L. Pirie, J. Kyle, L. S. Yap, P. Christen, G. G. Duthie: The effects of cranberry juice consumption on antioxidant status and biomarkers relating to heart disease and cancer in healthy human volunteers. Eur J Nutr. 2005, 45, 113-122.
22. R. Abu Amsha Cacetta, K. D. Croft, L. J. Beilin, I. A. Puddey. Ingestion of red wine significantly increases plasma phenolic acid concentrations but does not acutely affect ex vivo lipoprotein oxidizability. Am J Clin Nutr. 2000, 71, 67-74.
23. C. A. Rice Evans, N. J. Miller, G. Paganga: Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med. 1996, 20, 933-956.
24. C. Siquet, F. Paiva-Martins, J. F. L. C. Lima, S. Reis, F. Borges: Antioxidant profile of dihydroxy- and trihydroxyphenolic acids. A structure-activity relationship study. Free Rad Res. 2006, 40, 433-442.
25. R. P. Patel, D. Svistuneko, M. T. Wilson, V. M. Darley-Usmar: Reduction of Cu(II) by lipid peroxides: Implications for copper-dependent oxidation of low-density lipoprotein. Biochem J. 1997, 322, 425-433.
26. L. C. Bourne, C. A. Rice-Evans: The effect of the phenolic antioxidant ferulic acid on the oxidation of low density lipoprotein depends on the pro-oxidant used. Free Rad Res. 1997, 27, 337-344.
27. N. P. Seeram, M. G. Nair: Inhibition of lipid peroxidation and structure-activity related studies of the dietary constituents anthocyanins, anthocyanidins and catechins. J Agric Food Chem. 2002, 50, 5308-5312.
28. M. T. Satué-Gracia, M. Heinonen, E. N. Frankel: Anthocyanins as antioxidants on human low-density lipoprotein and lecithin-liposome system. J Agric Food Chem. 1997, 45, 3362-3367.
29. T. Tsuda, M. Watanabe, K. Oshima, S. Norinobu, S. W. Choi, S. Kawakishi, T. Osawa: Antioxidant activity of the anthocyanin pigments cyanidin 3-O-β- D -glucoside and cyanidin. J Agric Food Chem. 1994, 42, 2407-2410.