Calciotropic hormones and arterial physiology: "D"-lightful insights

Journal of the American Society of Nephrology

Volumn 18, Issue 2, 2007, Pages 369-373

  Towler, Dwight A ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BARNES JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; HORMONE; PARATHYROID HORMONE; PHOSPHATE; TESTOSTERONE; VITAMIN D;

ARTERY COMPLIANCE; BLOOD VESSEL CALCIFICATION; BLOOD VESSEL COMPLIANCE; BONE MINERALIZATION; BRACHIAL ARTERY; CALCIUM BLOOD LEVEL; CHRONIC KIDNEY DISEASE; EDITORIAL; HEART WORK; HUMAN; KIDNEY FAILURE; NONHUMAN; NUTRITIONAL STATUS; OSSIFICATION; OSTEOBLAST; OSTEOPOROSIS; OXIDATIVE STRESS; PHOSPHATE BLOOD LEVEL; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SECONDARY HYPERPARATHYROIDISM; SIGNAL TRANSDUCTION; SYSTOLIC HYPERTENSION; VASCULAR SMOOTH MUSCLE; VITAMIN D DEFICIENCY;

EID: 33846677722     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2006121367     Document Type: Editorial

References (43)

1. Abedin M, Tintut Y, Demer LL: Vascular calcification: Mechanisms and clinical ramifications. Arterioscler Thromb Vasc Biol 24: 1161-1170, 2004
2. Bostrom K, Watson KE, Horn S, Wortham C, Herman IM, Demer LL: Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest 91: 1800-1809, 1993
3. Shao JS, Cai J, Towler DA: Molecular mechanisms of vascular calcification: Lessons learned from the aorta. Arterioscler Thromb Vasc Biol 26: 1423-1430, 2006
4. Caira FC, Stock SR, Gleason TG, McGee EC, Huang J, Bonow RO, Spelsberg TC, McCarthy PM, Rahimtoola SH, Rajamannan NM: Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation. J Am Coll Cardiol 47: 1707-1712, 2006
5. Towler DA: Inorganic pyrophosphate: A paracrine regulator of vascular calcification and smooth muscle phenotype. Arterioscler Thromb Vasc Biol 25: 651-654, 2005
6. Collett GD, Canfield AE: Angiogenesis and pericytes in the initiation of ectopic calcification. Circ Res 96: 930-938, 2005
7. Moe SM, Chen NX: Pathophysiology of vascular calcification in chronic kidney disease. Circ Res 95: 560-567, 2004
8. London GM, Marchais SJ, Guerin AP, Metivier F: Arteriosclerosis, vascular calcifications and cardiovascular disease in uremia. Curr Opin Nephrol Hypertens 14: 525-531, 2005
9. London GM, Marty C, Marchais SJ, Guerin AP, Metivier F, de Vernejoul MC: Arterial calcifications and bone histomorphometry in end-stage renal disease. J Am Soc Nephrol 15: 1943-1951, 2004
10. Safar ME, Boudier HS: Vascular development, pulse pressure, and the mechanisms of hypertension. Hypertension 46: 205-209, 2005
11. London GM, Guerin AP, Verbeke FH, Pannier B, Boutouyrie P, Marchais SJ, Metivier F: Mineral metabolism and arterial functions in end-stage renal disease: Potential role of 25-hydroxyvitamin D deficiency. J Am Soc Nephrol 18: 613-620, 2007
12. Niederhoffer N, Lartaud-Idjouadiene I, Giummelly P, Duvivier C, Peslin R, Atkinson J: Calcification of medial elastic fibers and aortic elasticity. Hypertension 29: 999-1006, 1997
13. Blacher J, Safar ME: Large-artery stiffness, hypertension and cardiovascular risk in older patients. Nat Clin Pract Cardiovasc Med 2: 450-455, 2005
14. Feldman D, Glorieux FH, Pike JW: Vitamin D, 2nd Ed., Amsterdam, Elsevier Academic Press, 2005
15. Holick MF: Sunlight and vitamin D: Both good for cardiovascular health. J Gen Intern Med 17: 733-735, 2002
16. Haffner D, Hocher B, Muller D, Simon K, Konig K, Richter CM, Eggert B, Schwarz J, Godes M, Nissel R, Querfeld U: Systemic cardiovascular disease in uremic rats induced by 1,25(OH)2D3. J Hypertens 23: 1067-1075, 2005
17. Jono S, Nishizawa Y, Shioi A, Morii H: 1,25-Dihydroxyvitamin D3 increases in vitro vascular calcification by modulating secretion of endogenous parathyroid hormone-related peptide. Circulation 98: 1302-1306, 1998
18. Jono S, Nishizawa Y, Shioi A, Morii H: Parathyroid hormone-related peptide as a local regulator of vascular calcification. Its inhibitory action on in vitro calcification by bovine vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 17: 1135-1142, 1997
19. Henley C, Colloton M, Cattley RC, Shatzen E, Towler DA, Lacey D, Martin D: 1,25-Dihydroxyvitamin D3 but not cinacalcet HCl (Sensipar/Mimpara) treatment mediates aortic calcification in a rat model of secondary hyperparathyroidism. Nephrol Dial Transplant 20: 1370-1377, 2005
20. Price PA, Faus SA, Williamson MK: Warfarin-induced artery calcification is accelerated by growth and vitamin D. Arterioscler Thromb Vasc Biol 20: 317-327, 2000
21. Reynolds JL, Joannides AJ, Skepper JN, McNair R, Schurgers LJ, Proudfoot D, Jahnen-Dechent W, Weissberg PL, Shanahan CM: Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol 15: 2857-2867, 2004
22. Reynolds JL, Skepper JN, McNair R, Kasama T, Gupta K, Weissberg PL, Jahnen-Dechent W, Shanahan CM: Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. J Am Soc Nephrol 16: 2920-2930, 2005
23. Fritsch S, Lindner V, Welsch S, Massfelder T, Grima M, Rothhut S, Barthelmebs M, Helwig JJ: Intravenous delivery of PTH/PTHrP type 1 receptor cDNA to rats decreases heart rate, blood pressure, renal tone, renin angiotensin system, and stress-induced cardiovascular responses. J Am Soc Nephrol 15: 2588-2600, 2004
24. Crass MF 3rd, Jayaseelan CL, Darter TC: Effects of parathyroid hormone on blood flow in different regional circulations. Am J Physiol 253: R634-R639, 1987
25. Kosch M, Hausberg M, Vormbrock K, Kisters K, Gabriels G, Rahn KH, Barenbrock M: Impaired flow-mediated vasodilation of the brachial artery in patients with primary hyperparathyroidism improves after parathyroidectomy. Cardiovasc Res 47: 813-818, 2000
26. Kosch M, Hausberg M, Barenbrock M, Posadzy-Malaczynska A, Kisters K, Rahn KH: Arterial distensibility and pulse wave velocity in patients with primary hyperparathyroidism before and after parathyroidectomy. Clin Nephrol 55: 303-308, 2001
27. Weber K, Kaschig C, Erben RG: 1 Alpha-hydroxyvitamin D2 and 1 alpha-hydroxyvitamin D3 have anabolic effects on cortical bone, but induce intracortical remodeling at toxic doses in ovariectomized rats. Bone 35: 704-710, 2004
28. Coen G, Mantella D, Manni M, Balducci A, Nofroni I, Sardella D, Ballanti P, Bonucci E: 25-Hydroxyvitamin D levels and bone histomorphometry in hemodialysis renal osteodystrophy. Kidney Int 68: 1840-1848, 2005
29. Moselewski F, Ferencik M, Achenbach S, Abbara S, Cury RC, Booth SL, Jang IK, Brady TJ, Hoffmann U: Threshold-dependent variability of coronary artery calcification measurements: Implications for contrast-enhanced multi-detector row-computed tomography. Eur J Radiol 57: 390-395, 2006
30. Hoffmann U, Kwait DC, Handwerker J, Chan R, Lamuraglia G, Brady TJ: Vascular calcification in ex vivo carotid specimens: Precision and accuracy of measurements with multi-detector row CT. Radiology 229: 375-381, 2003
31. Demer LL: Effect of calcification on in vivo mechanical response of rabbit arteries to balloon dilation. Circulation 83: 2083-2093, 1991
32. Li YC, Qiao G, Uskokovic M, Xiang W, Zheng W, Kong J: Vitamin D: A negative endocrine regulator of the reninangiotensin system and blood pressure. J Steroid Biochem Mol Biol 89-90: 387-392, 2004
33. Rey FE, Pagano PJ: The reactive adventitia: Fibroblast oxidase in vascular function. Arterioscler Thromb Vasc Biol 22: 1962-1971, 2002
34. Lyakh LA, Sanford M, Chekol S, Young HA, Roberts AB: TGF-beta and vitamin D3 utilize distinct pathways to suppress IL-12 production and modulate rapid differentiation of human monocytes into CD83+ dendritic cells. J Immunol 174: 2061-2070, 2005
35. Schleithoff SS, Zittermann A, Tenderich G, Berthold HK, Stehle P, Koerfer R: Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 83: 754-759, 2006
36. Fahrleitner A, Dobnig H, Obernosterer A, Pilger E, Leb G, Weber K, Kudlacek S, Obermayer-Pietsch BM: Vitamin D deficiency and secondary hyperparathyroidism are common complications in patients with peripheral arterial disease. J Gen Intern Med 17: 663-669, 2002
37. Lips P: Vitamin D physiology. Prog Biophys Mol Biol 92: 4-8, 2006
38. Zerwekh JE, Ruml LA, Gottschalk F, Pak CY: The effects of twelve weeks of bed rest on bone histology, biochemical markers of bone turnover, and calcium homeostasis in eleven normal subjects. J Bone Miner Res 13: 1594-1601, 1998
39. van Driel M, Koedam M, Buurman CJ, Hewison M, Chiba H, Uitterlinden AG, Pols HAP, van Leeuwen JPTM: Evidence for auto/paracrine actions of vitamin D in bone: lalpha-hydroxylase expression and activity in human bone cells. FASEB J 20: E1811-E1819, 2006
40. Zehnder D, Bland R, Chana RS, Wheeler DC, Howie AJ, Williams MC, Stewart PM, Hewison M: Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: A novel autocrine determinant of vascular cell adhesion. J Am Soc Nephrol 13: 621-629, 2002
41. Esteban L, Vidal M, Dusso A: 1Alpha-hydroxylase transactivation by gamma-interferon in murine macrophages requires enhanced C/EBPbeta expression and activation. J Steroid Biochem Mol Biol 89-90: 131-137, 2004
42. Lai CF, Seshadri V, Huang K, Shao JS, Cai J, Vattikuti R, Schumacher A, Loewy AP, Denhardt DT, Rittling SR, Towler DA: An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells. Circ Res 98: 1479-1489, 2006
43. Kato S, Matsumoto T, Kawano H, Sato T, Takeyama K: Function of androgen receptor in gene regulations. J Steroid Biochem Mol Biol 89-90: 627-633, 2004