Influence of different intravenous lipid emulsions on hepatobiliary dysfunction in a rabbit model

Journal of Pediatric Gastroenterology and Nutrition

Volumn 44, Issue 2, 2007, Pages 237-244

  Kohl, Martina ^a   Wedel, Thilo ^a   Entenmann, Andreas ^a   Stuttmann, Julia ^a   Bendiks, Meike ^a   Loff, Steffan ^b,c   Köster, Stefan ^a   Ortfeld, Stefan ^a   Bos, Inge ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Hepatobiliary dysfunction; Intravenous lipid emulsion; n 3 fatty acids; Total parenteral nutrition

Indexed keywords

FISH OIL; LIPID EMULSION; OLIVE OIL; OMEGA 3 FATTY ACID; SOYBEAN OIL EMULSION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DISEASE SEVERITY; ENTERIC FEEDING; EXPERIMENTAL MODEL; HEPATOBILIARY DISEASE; HISTOLOGY; LIVER FIBROSIS; LIVER INJURY; LIVER TOXICITY; LONG TERM CARE; MALE; NONHUMAN; PREPUBERTY; PRIORITY JOURNAL; RABBIT; TREATMENT OUTCOME;

ANIMALS; BILIARY TRACT; DISEASE MODELS, ANIMAL; FAT EMULSIONS, INTRAVENOUS; HEPATOCYTES; LIVER; LIVER CIRRHOSIS; MALE; PARENTERAL NUTRITION, TOTAL; RABBITS;

ANIMALIA; GLYCINE MAX; ORYCTOLAGUS CUNICULUS;

EID: 33846646548     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpg.0000252193.99331.03     Document Type: Article

References (31)

1. Moss RL, Das JB, Raffensperger JG. Total parenteral nutrition-associated cholestasis: clinical and histopathologic correlation. J Pediatr Surg 1993;28:1270-5.
2. Beath SV, Davies P, Papadopoulou A, et al. Parenteral nutrition-related cholestasis in postsurgical neonates: multivariate analysis of risk factors. J Pediatr Surg 1996;31:604-6.
3. Kaufman SS. Prevention of parenteral nutrition-associated liver disease in children. Pediatr Transplant 2002;6:37-42.
4. Loff S, Kabs F, Witt K, et al. Polyvinylchloride infusion lines expose infants to large amounts of toxic plasticizers. J Pediatr Surg 2000;35:1775-81.
5. Iyer KR, Spitz L, Clayton P. BAPS prize lecture: new insight into mechanisms of parenteral nutrition-associated cholestasis: role of plant sterols. British Association of Paediatric Surgeons. J Pediatr Surg 1998;33:1-6.
6. Colomb V, Jobert-Giraud A, Lacaille F, et al. Role of lipid emulsions in cholestasis associated with long-term parenteral nutrition in children. JPEN J Parenter Enteral Nutr 2000;24: 345-350.
7. Cavicchi M, Crenn P, Beau P, et al. Severe liver complications associated with long-term parenteral nutrition are dependent on lipid parenteral input. Transplant Proc 1998;30:2547.
8. Mayer K, Meyer S, Reinholz-Muhly M, et al. Short-time infusion of fish oil-based lipid emulsions, approved for parenteral nutrition, reduces monocyte proinflammatory cytokine generation and adhesive interaction with endothelium in humans. J Immunol 2003;171: 4837-43.
9. Jones A, Selby PJ, Viner C, et al. Tumour necrosis factor, cholestatic jaundice, and chronic liver disease. Gut 1990;31:938-9.
10. Curran TJ, Uzoaru I, Das JB, et al. The effect of cholecystokininoctapeptide on the hepatobiliary dysfunction caused by total parenteral nutrition. J Pediatr Surg 1995;30:242-7.
11. Loff S, Kranzlin B, Moghadam M, et al. Parenteral nutrition-induced hepatobiliary dysfunction in infants and prepubertal rabbits. Pediatr Surg Int 1999;15:479-82.
12. Loff S, Waag KL, Kranzlin B, et al. Long-term total parenteral nutrition-induced hepatobiliary dysfunction in a rabbit model. J Pediatr Surg 1998;33:694-9.
13. Jeppesen PB, Hoy CE, Mortensen PB. Essential fatty acid deficiency in patients receiving home parenteral nutrition. Am J Clin Nutr 1998;68:126-33.
14. Cavicchi M, Beau P, Crenn P, et al. Prevalence of liver disease and contributing factors in patients receiving home parenteral nutrition for permanent intestinal failure. Ann Intern Med 2000;132:525-32.
15. Parola M, Leonarduzzi G, Robino G, et al. On the role of lipid peroxidation in the pathogenesis of liver damage induced by longstanding cholestasis. Free Radic Biol Med 1996;20:351-9.
16. Pitkanen OM, Luukkainen P, Andersson S. Attenuated lipid peroxidation in preterm infants during subsequent doses of intravenous lipids. Biol Neonate 2004;85:184-7.
17. Pironi L, Ruggeri E, Zolezzi C, et al. Lipid peroxidation and antioxidant status in adults receiving lipid-based home parenteral nutrition. Am J Clin Nutr 1998;68:888-93.
18. Weinberger B, Watorek K, Strauss R, et al. Association of lipid peroxidation with hepatocellular injury in preterm infants. Crit Care 2002;6:521-5.
19. Ok E, Yilmaz Z, Karakucuk I, et al. Use of olive oil based emulsions as an alternative to soybean oil based emulsions in total parenteral nutrition and their effects on liver regeneration following hepatic resection in rats. Ann Nutr Metab 2003;47:221-7.
20. Gobel Y, Koletzko B, Bohles HJ, et al. Parenteral fat emulsions based on olive and soybean oils: a randomized clinical trial in preterm infants. J Pediatr Gastroenterol Nutr 2003;37:161-7.
21. Goulet O, de Potter S, Antebi H, et al. Long-term efficacy and safety of a new olive oil-based intravenous fat emulsion in pediatric patients: a double-blind randomized study. Am J Clin Nutr 1999;70:338-45.
22. Trauner M, Fickert P, Stauber RE. Inflammation-induced cholestasis. J Gastroenterol Hepatol 1999;14:946-59.
23. Benyon RC, Arthur MJ. Mechanisms of hepatic fibrosis. J Pediatr Gastroenterol Nutr 1998;27:75-85.
24. Ling PR, Khaodhiar L, Bistrian BR, et al. Inflammatory mediators in patients receiving long-term home parenteral nutrition. Dig Dis Sci 2001;46:2484-9.
25. Bistrian BR. Clinical aspects of essential fatty acid metabolism: Jonathan Rhoads Lecture. JPEN J Parenter Enteral Nutr 2003;27: 168-75.
26. Mayer K, Grimm H, Grimminger F, et al. Parenteral nutrition with n-3 lipids in sepsis. Br J Nutr 2002;87:S69-75.
27. Koller M, Senkal M, Kemen M, et al. Impact of omega-3 fatty acid enriched TPN on leukotriene synthesis by leukocytes after major surgery. Clin Nutr 2003;22:59-64.
28. Mayer K, Gokorsch S, Fegbeutel C, et al. Parenteral nutrition with fish oil modulates cytokine response in patients with sepsis. Am J Respir Crit Care Med 2003;167:1321-8.
29. Furst P, Kuhn KS. Fish oil emulsions: what benefits can they bring? Clin Nutr 2000;19:7-14.
30. Hata S, Kamata S, Nezu R, et al. A newborn rabbit model for total parenteral nutrition: effects of nutritional components on cholestasis. JPEN J Parenter Enteral Nutr 1989;13:265-71.
31. Moss RL, Haynes AL, Pastuszyn A, et al. Methionine infusion reproduces liver injury of parenteral nutrition cholestasis. Pediatr Res 1999;45:664-8.