2(S)-(Cycloalk-1-enecarbonyl)-1-(4-phenyl-butanoyl)pyrrolidines and 2(S)-(aroyl)-1-(4-phenylbutanoyl)pyrrolidines as prolyl oligopeptidase inhibitors

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 5, 2007, Pages 2024-2031

  Jarho, Elina M ^a   Venäläinen, Jarkko I ^a   Poutiainen, Sami ^a   Leskinen, Harri ^a   Vepsäläinen, Jouko ^a   Christiaans, Johannes A M ^a   Forsberg, Markus M ^a   Männistö, Pekka T ^a   Wallén, Erik A A ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

, Unsaturated carbonyl group; 1 Cyclopentene; 2 Thiophene; Prolyl oligopeptidase

Indexed keywords

AMIDE; BENZENE DERIVATIVE; CARBONYL DERIVATIVE; CYCLOALKANE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROLYL ENDOPEPTIDASE INHIBITOR; PYRROLIDINE DERIVATIVE; SUAM 1221; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG CONJUGATION; DRUG POTENCY; IC 50; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTUM YIELD; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEASE INHIBITORS; PYRROLIDINES; SERINE ENDOPEPTIDASES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWINE;

EID: 33846608684     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.12.036     Document Type: Article

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