Brain lipid peroxidation and antioxidant systems of young rats in chronic fluoride intoxication

Fluoride

Volumn 35, Issue 3, 2002, Pages 197-203

  Shivarajashankara, Y M ^a   Shivashankara, A R ^a   Gopalakrishna Bhat, P ^a   Hanumanth Rao, S ^a  

^a M R MEDICAL COLLEGE   (India)

Author keywords

Albino rats; Antioxidants; Ascorbic acid; Fluoride intoxication; Glutathione; Glutathione peroxidase; Glutathione S transferase; Lipid peroxidation; Oxidative stress; Sodium fluoride

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; DRINKING WATER; FLUORIDE; FLUORIDE SODIUM; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID; MALONALDEHYDE;

ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOASSAY; BRAIN HOMOGENATE; BRAIN METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; FLUOROSIS; LIPID PEROXIDATION; NEUROPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; RAT;

EID: 0036694579     PISSN: 00154725     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Bhussry BR, Demole V, Hodge HC, Jolly SS, Singh A, Taves DR. Toxic effects of larger doses of fluoride. In: Fluorides and human health. Geneva: WHO; 1970. p. 225-73.
2. Zhavoronkov AA. Non-skeletal forms of fluorosis. Arch Pathol 1977;39: 83-91.
3. Monsour PA, Kruger BJ. Effect of fluoride on soft tissues in vertebrates. Fluoride 1985;18:53-61.
4. Waldbott GL, Burgstahler AW, McKinney HL. Fluoridation: the great dilemma. Lawrence, Kansas: Coronado Press; 1978.
5. Mullenix PJ, Denbesten PK, Schunior A, Keman WJ. Neurotoxicity of sodium fluoride in rats. Neurotoxicol Teratol 1995;17:169-77.
6. Shivarajashankara YM, Shivashankara AR, Gopalakrishna Bhat P, Muddanna Rao S, Hanumanth Rao S. Histological changes in the brain of young fluoride-intoxicated rats. Fluoride 2002;35:12-21.
7. Vani ML, Reddy KP. Effect of fluoride accumulation on some enzymes of brain and gastrocnemius muscle of mice. Fluoride 2000;33:17-26.
8. Shashi A. Studies on alterations in brain lipid metabolism following experimental fluorosis. Fluoride 1992;25:77-84.
9. Shashi A, Singh JP, Thapar SP. Effect of long-term administration of fluoride on levels of proteins, free amino acids and RNA in rabbit brain. Fluoride 1994;27:155-9.
10. Patel PD, Chinoy NJ. Influence of fluoride on biological free radical reactions in ovary of mice and its reversal. Fluoride 1998;31:S27.
11. Rzeuski R, Chlubek D, Machoy Z. Interactions between fluoride and biological free radical reactions. Fluoride 1998;31:43-5.
12. Sharma A, Chinoy NJ. Role of free radicals in fluoride-induced toxicity in liver and kidney of mice and its reversal. Fluoride 1998;31:S26.
13. Shivarajashankara YM, Shivashankara AR, Gopalakrishna Bhat P, Hanumanth Rao S. Effect of fluoride intoxication on lipid peroxidation and antioxidant systems in rats. Fluoride 2001;34:108-13.
14. Shivarajashankara YM, Shivashankara AR, Hanumanth Rao S, Gopalakrishna Bhat P. Oxidative stress in children with endemic skeletal fluorosis. Fluoride 2001;34:103-7.
15. Shivashankara AR, Shivarajashankara YM, Gopalakrishna Bhat P, Hanumanth Rao S. Lipid peroxidation and antioxidant defense systems in liver of rats in chronic fluoride toxicity. Bull Environ Contam Toxicol 2002;68:612-6.
16. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8.
17. Akarboom TPM, Sies H. Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples. In: Jakoby WB, editor. Methods in enzymology, Vol. 77. New York: Academic Press; 1981. p. 373-82.
18. Beutler E, Duron O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med 1963;61:882-8.
19. Wendel A. Glutathione peroxidase. In: Jakoby WB, editor. Methods in enzymology, Vol. 77. New York: Academic Press; 1981. p. 325-33.
20. Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferase: the first enzymatic step in mercapturic acid formation. J Biol Chem 1974;249:7130-9.
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with folin-phenol reagent. J Biol Chem 1951;193:265-75.
22. Omaye ST, Turnbull JD, Sauberlich HE. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. In: MaCormick DB, Wright LD, editors. Methods in enzymology, Vol. 62. New York: Academic Press; 1979. p. 3-8.
23. Halliwell B, Gutteridge JMC. Oxygen radicals and the nervous system. Trends Neurosci 1985;8:22-6.
24. th Ed. Philadelphia: Lippincott Raven; 1985.
25. Saralakumari D, Ramakrishna Rao P. Red cell membrane alterations in human chronic fluoride toxicity. Biochem Int 1991;23:639-48.
26. Zhi-Zhong G, Pei-Si Y, Nai-Den Y, Zong-Jie Z. An experimental study of blood biochemical diagnostic indices for chronic fluorosis. Fluoride 1989;22: 112-8.
27. Chow CK, Tappel AL. An enzymatic protective mechanism against lipid peroxidation damage to lungs of ozone-exposed rats. Lipids 1972;7:518-24.
28. Edes I, Piros G, Toth GK, Csanady M, Kovacs K. Effects of long-term alcohol ingestion on glutathione metabolizing enzymes and taurine contents in the myocardium of rats. Cardiovasc Res 1986;20:918-21.
29. Dierickx PJ. Activation by sodium fluoride of drug-metabolizing enzymes in rat hepatoma-derived Fa 32 cells. FEBS Lett 1998;422:185-8.
30. Pickett CB, Lu YHA. Glutathione S-transferases: gene structure, regulation and biological function. In: Richardson CC, editor. Annual review of biochemistry, Vol. 58. California: Annual Reviews Inc; 1989. p. 743-64.
31. Jacob RA, Buri RJ. Oxidative damage and defense. Am J Clin Nutr 1996;63: 985S-90S.
32. Chinoy NJ. Metabolic significances of ascorbic acid in animal and human tissues. J Animal Morphol Physiol (Silver jubilee commemorative volume) 1978; 68-75.
33. Chinoy NJ, Sharma M, Michael M. Beneficial effects of ascorbic acid and calcium on reversal of fluoride toxicity in male rats. Flouride 1993;26:45-56.