Flexible strategy for differentially 3,5-disubstituted 4-oxypyridin-2(1H)- ones based on site-selective Pd-catalyzed cross-coupling reactions

Organic Letters

Volumn 9, Issue 2, 2007, Pages 271-274

  Conreaux, David ^a   Bossharth, Emmanuel ^a   Monteiro, Nuno ^a   Desbordes, Philippe ^b   Vors, Jean Pierre ^b   Balme, Geneviève ^a  

^a UNIVERSITÉ LYON 1   (France)

^b BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; PALLADIUM; PYRIDONE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ACETATES; CATALYSIS; MOLECULAR STRUCTURE; PALLADIUM; PYRIDONES; STEREOISOMERISM;

EID: 33846581473     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol062721u     Document Type: Article

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34. The structure of 3 has been secured by X-ray analysis. See Supporting Information.
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42. For metal-free methods, see: Olivi, N.; Thomas, E.; Peyrat, J.-F.; Alami, M.; Brion, J.-D. Synlett 2004, 2175 and references therein.
43. 3-Acetyl-4-oxypyridones have been used as intermediates in the syntheses of tenellin and ilicicolin H. See refs 2a,b. For other approaches to 3-acetyl-5-aryl-4-oxypyridones, see refs 2c and 3a,b.