Neural stem cells as therapeutic agents for CNS injuries and disorders

International Congress Series

Volumn 1252, Issue C, 2003, Pages 493-498

  Okano, Hideyuki ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Musashi1; nestin GFP; Neural stem cells (NSCs); Parkinson's disease; Spinal cord injury

Indexed keywords

EID: 33846566986     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0531-5131(03)00097-9     Document Type: Article

References (25)

1. H. Okano Stem cell biology of the central nervous system J. Neurosci. Res. 69 6 2002 698 707
2. D.W. Pincus H.M. Keyoung C. Harrison-Restelli R.R. Goodman R.A. Fraser M. Edgar S. Sakakibara H. Okano M. Nedergaard S.A. Goldman Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells Ann. Neurol. 43 5 1998 576 585
3. N.S. Roy S. Wang L. Jiang J. Kang A. Benraiss C. Harrison-Restelli R.A. Fraser W.T. Couldwell A. Kawaguchi H. Okano M. Nedergaard S.A. Goldman In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus Nat. Med. 6 3 2000 271 277
4. N.S. Roy A. Benraiss S. Wang R.A. Fraser R. Goodman W.T. Couldwell M. Nedergaard A. Kawaguchi H. Okano S.A. Goldman Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone J. Neurosci. Res. 59 3 2000 321 331
5. S. Sakakibara T. Imai K. Hamaguchi M. Okabe J. Aruga K. Nakajima D. Yasutomi T. Nagata Y. Kurihara S. Uesugi T. Miyata M. Ogawa K. Mikoshiba H. Okano Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell Dev. Biol. 176 2 1996 230 242
6. S. Sakakibara H. Okano Expression of neural RNA-binding proteins in the postnatal CNS: implications of their roles in neuronal and glial cell development J. Neurosci. 17 21 1997 8300 8312
7. Y. Kaneko S. Sakakibara T. Imai A. Suzuki Y. Nakamura K. Sawamoto Y. Ogawa Y. Toyama T. Miyata H. Okano Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells Dev. Neurosci. 22 1–2 2000 139 153
8. S. Sakakibara Y. Nakamura H. Satoh H. Okano RNA-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS J. Neurosci. 21 20 2001 8091 8107
9. T. Imai A. Tokunaga T. Yoshida M. Hashimoto K. Mikoshiba G. Weinmaster M. Nakafuku H. Okano The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA Mol. Cell. Biol. 21 12 2001 3888 3900
10. H. Okano T. Imai M. Okabe Musashi: a translational regulator of cell fate J. Cell Sci. 115 2002 1355 1359 Pt 7
11. S. Sakakibara Y. Nakamura M. Koike H. Takano Y. Uchiyama T. Noda H. Okano RNA-binding protein Musashi family, roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation Proc. Natl. Acad. Sci. U. S. A. 99 23 2002 15194 15199
12. A. Kawaguchi T. Miyata K. Sawamoto N. Takashita A. Murayama W. Akamatsu M. Ogawa M. Okabe Y. Tano S.A. Goldman H. Okano Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells Mol. Cell. Neurosci. 17 2 2001 259 273
13. O. Lindvall Neural transplants in Parkinson's disease S.B. Dunnett A. Bjorklund Functional Neural Transplantation 1994 Raven New York
14. J.H. Kordower T.B. Freeman B.J. Snow F.J. Vingerhoets E.J. Mufson P.R. Sanberg R.A. Hauser D.A. Smith G.M. Nauert D.P. Peri Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease N. Engl. J. Med. 332 17 1995 1118 1124
15. K. Sawamoto N. Nakao K. Kakishita Y. Ogawa Y. Toyama A. Yamamoto M. Yamaguchi K. Mori S.A. Goldman T. Itakura H. Okano Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene J. Neurosci. 21 11 2001 3895 3903
16. H. Kawano K. Ohyama K. Kawamura I. Nagatsu Migration of dopaminergic neurons in the embryonic mesencephalon of mice Brain Res. Dev. Brain Res. 86 1–2 1995 101 113
17. K. Sawamoto N. Nakao K. Kobayashi N. Matsushita H. Takahashi K. Kakishita A. Yamamoto T. Yoshizaki T. Terashima F. Murakami T. Itakura H. Okano Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons Proc. Natl. Acad. Sci. U. S. A. 98 11 2001 6423 6428
18. H. Okano T. Yoshizaki T. Shimazaki K. Sawamoto Related Articles, isolation and transplantation of dopaminergic neurons and neural stem cells Parkinsonism Relat. Disord. 9 1 2002 23
19. J.H. Kim J.M. Auerbach J.A. Rodriguez-Gomez I. Velasco D. Gavin N. Lumelsky S.H. Lee J. Nguyen R. Sanchez-Pernaute K. Bankiewicz R. McKay Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease Nature 418 6893 2002 50 56
20. L.M. Bjorklund R. Sanchez-Pernaute S. Chung T. Andersson I.Y. Chen K.S. McNaught A.L. Brownell B.G. Jenkins C. Wahlestedt K.S. Kim O. Isacson Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model Proc. Natl. Acad. Sci. U. S. A. 99 4 2002 2344 2349
21. A. Arvidsson T. Collin D. Kirik Z. Kokaia O. Lindvall Neuronal replacement from endogenous precursors in the adult brain after stroke Nat. Med. 8 9 2002 963 970
22. H. Nakatomi T. Kuriu S. Okabe S. Yamamoto O. Hatano N. Kawahara A. Tamura T. Kirino M. Nakafuku Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors Cell 110 4 2002 429 441
23. Y. Ogawa K. Sawamoto T. Miyata S. Miyao M. Watanabe M. Nakamura B.S. Bregman M. Koike Y. Uchiyama Y. Toyama H. Okano Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats J. Neurosci. Res. 69 6 2002 925 933
24. H. Okano Neural stem cells: progression of basic research and perspective for clinical application Keio J. Med. 51 3 2002 115 128
25. H. Okano Y. Ogawa M. Nakamura S. Kaneko A. Iwanami A. Toyama Transplantation of neural stem cells into the spinal cord after injury Semin. Cell Dev. Biol. 2003 (in press)