Isolation and transplantation of dopaminergic neurons and neural stem cells

Parkinsonism and Related Disorders

Volumn 9, Issue 1, 2002, Pages 23-28

  Okano, Hideyuki ^a,b   Yoshizaki, Takahito ^a,b   Shimazaki, Takuya ^a,b   Sawamoto, Kazunobu ^c,d  

^a KEIO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dopaminergic neurons; Neural stem cells; Parkinson's disease

Indexed keywords

AMPHETAMINE; DOPAMINE TRANSPORTER; GREEN FLUORESCENT PROTEIN; KI 67 ANTIGEN; NESTIN;

BIOLOGICAL MODEL; CELL ASSAY; CELL ISOLATION; CELL LABELING; CONFERENCE PAPER; DOPAMINERGIC NERVE CELL; ENZYME CHEMISTRY; MESENCEPHALON; NERVE FIBER; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; STEM CELL; STEM CELL TRANSPLANTATION; TECHNIQUE; TISSUE CULTURE CELL; TRANSGENIC MOUSE;

ANIMALS; BRAIN TISSUE TRANSPLANTATION; CELL SEPARATION; DOPAMINE; HUMANS; NEURONS; PARKINSON DISEASE; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 0036825060     PISSN: 13538020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1353-8020(02)00041-X     Document Type: Conference Paper

References (35)

1. Nagatsu T., Yamaguchi T., Rahman M.K., Trocewicz J., Oka K., Hirata Y., Nagatsu I., Narabayashi H., Kondo T., Iizuka R. Catecholamine-related enzymes and the biopterin cofactor in Parkinson's disease and related extrapyramidal diseases. Hasseler R.G., Christ J.F. Advances in neurology. vol. 40:1984;467-473 Raven, New York.
2. Agid Y., Javoy-Agid F., Ruberg M. Biochemistry of neurotransmitter in Parkinson's disease. Marsden C.D., Fahn S. Movement disorders. vol. 2:1987;166-230 Butterworths, London.
3. Damier P., Hirsch E.C., Agid Y., Graybiel A.M. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain. 122:1999;1437-1448.
4. Bjorklund A., Stenevi U. Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants. Brain Res. 177:1979;555-560.
5. Brundin P., Strecker R.E., Widner H., Clarke D.J., Nilsson O.G., Astedt B., Lindvall O., Bjorklund A. Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behavior, and dopamine release. Exp Brain Res. 70:1988;192-208.
6. Sauer H., Brundin P. Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts. Restor Neurol Neurosci. 2:1991;123-135.
7. Lindvall O. Neural transplants in Parkinson's disease. Dunnett S.B., Bjorklund A. Functional neural transplantation. 1994;103-137 Raven, New York.
8. Frodl E.M., Duan W.M., Sauer H., Kupsch A., Brundin P. Human embryonic dopamine neurons xenografted to the rat: effects of cryopreservation and varying regional source of donor cells on transplant survival, morphology, and function. Brain Res. 647:1994;286-298.
9. Nakao N., Frodl E.M., Duan W.M., Widner H., Brundin P. Lazaroids improve the survival of grafted rat embryonic dopaminergic neurons. Proc Natl Acad Sci USA. 91:1994;12408-12412.
10. Haque N.S., LeBlanc C.J., Isacson O. Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDA-lesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons. Cell Transplant. 6:1997;239-248.
11. Bjorklund A., Lindvall O. Cell replacement therapies for central nervous system disorders. Nat Neurosci. 3:2000;537-544.
12. Sawamoto K., Nakao N., Kakishita K., Ogawa Y., Toyama Y., Yamamoto A., Yamaguchi M., Mori K., Goldman S.A., Itakura T., Okano H. Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci. 21:2001;3895-3903.
13. Sawamoto K., Nakao N., Kobayashi K., Matsushita N., Takahashi H., Kakishita K., Yamamoto A., Yoshizaki T., Terashima T., Murakami F., Itakura T., Okano H. Visualization and direct isolation of midbrain dopaminergic neurons expressing GFP. Proc Natl Acad Sci USA. 98:2001;6423-6428.
14. Hynes M., Rosenthal A. Specification of dopaminergic and serotonergic neurons in the vertebrate CNS. Curr Opin Neurobiol. 9:1999;26-36.
15. Studer L., Tabar V., McKay R.D. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci. 1:1998;290-295.
16. Zimmerman L., Parr B., Lendahl U., Cunningham M., McKay R., Gavin B., Mann J., Vassileva G., McMahon A. Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron. 12:1994;11-24.
17. Lothian C., Lendahl U. An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells. Eur J Neurosci. 9:1997;452-462.
18. Kawaguchi A., Miyata T., Sawamoto K., Takashita N., Murayama A., Akamatsu W., Ogawa M., Okabe M., Tano Y., Goldman S.A., Okano H. Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Mol Cell Neurosci. 17:2001;259-273.
19. Roy N.S., Wang S., Jiang L., Kang J., Benraiss A., Harrison-Restelli C., Fraser R.A., Couldwell W.T., Kawaguchi A., Okano H., Nedergaard M., Goldman S.A. In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nat Med. 6:2000;271-277.
20. Yamaguchi M., Saito H., Suzuki M., Mori K. Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice. NeuroReport. 11:2000;1991-1996.
21. Reynolds B.A., Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science. 255:1992;1707-1710.
22. Kawano H., Ohyama K., Kawamura K., Nagatsu I. Migration of dopaminergic neurons in the embryonic mesencephalon of mice. Brain Res Dev Brain Res. 86:1995;101-113.
23. Gerdes J., Schwab U., Lemke H., Stein H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer. 31:1983;13-20.
24. Schmidt R.H., Björklund A., Stenevi U., Dunnett S.B., Gage F.H. Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism. Acta Physiol. 522:(Suppl. 2):1983;19-28.
25. Min N., Joh T.H., Kim K.S., Pen C., Son J.H. 5′ upstream DNA sequence of the rat tyrosine hydroxylase gene directs high-level and tissue-specific expression to catecholaminergic neurons in the central nervous system of transgenic mice. Mol Brain Res. 27:1994;281-289.
26. Kim S.J., Lee J.W., Chun H.S., Joh T.H., Son J.H. Monitoring catecholamine differentiation in the embryonic brain and peripheral neurons using E. coli lacZ as a reporter gene. Mol Cells. 7:1997;394-398.
27. Kalsbeek A., Voorn P., Buijs R.M. Development of dopamine-containing systems in the CNS. Björklund A., Hökfelt T., Tohyama T. Handbook of chemical neuroanatomy. vol. 10:1992;63-112 Elsevier, Amsterdam.
28. Studer L., Tabar V., McKay R.D. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci. 1:1998;290-295.
29. Wagner J., Akerud P., Castro D.S., Holm P.C., Canals J.M., Snyder E.Y., Perlmann T., Arenas E. Induction of a midbrain dopaminergic phenotype in Nurrl-overexpressing neural stem cells by type 1 astrocytes. Nat Biotechnol. 7:1999;653-659.
30. Lee S.H., Lumelsky N., Studer L., Auerbach J.M., McKay R.D. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol. 18:2000;675-679.
31. Kawasaki H., Mizuseki K., Nishikawa S., Kaneko S., Kuwana Y., Nakanishi S., Nishikawa S., Sasai Y. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron. 28:2000;31-40.
32. Svendsen C.N., Clarke D.J., Rosser A.E., Dunnett S.B. Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system. Exp Neurol. 137:1996;376-388.
33. Svendsen C.N., Caldwell M.A., Shen J., ter Borg M.G., Rosser A.E., Tyers P., Karmiol S., Dunnett S.B. Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease. Exp Neurol. 148:1997;135-146.
34. Brundin P., Björklund A. Survival of expanded dopaminergic precursors is critical for clinical trials. Nat Neurosci. 1:1998;537.
35. Okono H. Strategies of regenerative medicine. KAST Report. 13:2001;24-29.