15-Deoxyspergualin inhibits eukaryotic protein synthesis through eIF2α phosphorylation

Biochemical Journal

Volumn 401, Issue 2, 2007, Pages 411-420

  Ramya, T N C ^a   Surolia, Namita ^b   Surolia, Avadhesha ^a,c  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

^c NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

15 deoxyspergualin; Eukaryotic initiation factor 2 ; Haem regulated inhibitor; Heat shock protein; Protein synthesis

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CELLS; ENZYME INHIBITION; REACTION KINETICS; TUMORS;

DEOXYSPERGUALIN; EUKARYOTIC INITIATION FACTOR; HAEM REGULATED INHIBITOR; HEAT SHOCK PROTEIN; PROTEIN SYNTHESIS;

PROTEINS;

15 DEOXYSPERGUALIN; HEAT SHOCK PROTEIN 70; INITIATION FACTOR 2ALPHA; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; EUKARYOTIC CELL; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RETICULOCYTE LYSATE; THYROID CARCINOMA;

ANIMALS; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; GUANIDINES; HSP70 HEAT-SHOCK PROTEINS; HUMANS; JURKAT CELLS; K562 CELLS; MICE; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RABBITS; RETICULOCYTES; TUMOR CELLS, CULTURED;

EUKARYOTA; MAMMALIA;

EID: 33846536810     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060879     Document Type: Article

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