Comparing diffusion-weighted and T2-weighted MR imaging for the quantification of infarct size in a neonatal rat hypoxic-ischemic model at 24 h post-injury

International Journal of Developmental Neuroscience

Volumn 25, Issue 1, 2007, Pages 1-5

  Wang, Yanxin ^a   Cheung, Pik To ^a   Shen, Gary X ^a   Bhatia, Inderjeet ^a   Wu, Ed Xue ^a   Qiu, Deqiang ^a   Khong, Pek Lan ^b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apparent diffusion coefficient; Diffusion weighted; Hypoxic ischemic; Neonatal rat; T2 weighted

Indexed keywords

TRIPHENYLTETRAZOLIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; HEMISPHERE; MULTIPLE LINEAR REGRESSION ANALYSIS; NEWBORN; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; STAINING;

ANIMALS; ANIMALS, NEWBORN; BRAIN INFARCTION; DISEASE MODELS, ANIMAL; HYPOXIA-ISCHEMIA, BRAIN; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 33846474269     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2006.12.003     Document Type: Article

References (35)

1. Adcock K.H., Nedelcu J., Loenneker T., Martin E., Wallimann T., and Wagner B.P. Neuroprotection of creatine supplementation in neonatal rats with transient cerebral hypoxia-ischemia. Dev. Neurosci. 24 (2002) 382-388
2. Albensi B.C., Schweizer M.P., Rarick T.M., and Filloux F. Magnetic resonance imaging of hypoxic-ischemic brain injury in the neonatal rat. Invest. Radiol. 33 (1998) 377-385
3. Albensi B.C., Schweizer M.P., Rarick T.M., and Filloux F. Unilateral hypoxic-ischemic injury in the neonatal rat brain evaluated by in vivo MRI. Correlation with histopathology and neuroprotection by MK-801. Invest. Radiol. 34 (1999) 249-261
4. Balduini W., De A.V., Mazzoni E., and Cimino M. Simvastatin protects against long-lasting behavioral and morphological consequences of neonatal hypoxic/ischemic brain injury. Stroke 32 (2001) 2185-2191
5. Dingley J., Tooley J., Porter H., and Thoresen M. Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia. Stroke 37 (2006) 501-506
6. Feng Y., Paul I.A., and LeBlanc M.H. Nicotinamide reduces hypoxic ischemic brain injury in the newborn rat. Brain Res. Bull 69 (2006) 117-122
7. Fiehler J., Foth M., Kucinski T., Knab R., Von B.M., Weiller C., Zeumer H., and Rother J. Severe ADC decreases do not predict irreversible tissue damage in humans. Stroke 33 (2002) 79-86
8. Hasegawa Y., Latour L.L., Formato J.E., Sotak C.H., and Fisher M. Spreading waves of a reduced diffusion coefficient of water in normal and ischemic rat brain. J. Cereb. Blood Flow Metab. 15 (1995) 179-187
9. Hoehn-Berlage M., Norris D.G., Kohno K., Mies G., Leibfritz D., and Hossmann K.A. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: the relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances. J. Cereb. Blood Flow Metab. 15 (1995) 1002-1011
10. Jatana M., Singh I., Singh A.K., and Jenkins D. Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats. Pediatr. Res. 59 (2006) 684-689
11. Loubinoux I., Volk A., Borredon J., Guirimand S., Tiffon B., Seylaz J., and Meric P. Spreading of vasogenic edema and cytotoxic edema assessed by quantitative diffusion and T2 magnetic resonance imaging. Stroke 28 (1997) 419-426
12. Meng S., Qiao M., Lin L., Del Bigio M.R., Tomanek B., and Tuor U.I. Correspondence of AQP4 expression and hypoxic-ischaemic brain oedema monitored by magnetic resonance imaging in the immature and juvenile rat. Eur. J. Neurosci. 19 (2004) 2261-2269
13. Meng X., Fisher M., Shen Q., Sotak C.H., and Duong T.Q. Characterizing the diffusion/perfusion mismatch in experimental focal cerebral ischemia. Ann. Neurol. 55 (2004) 207-212
14. Miyasaka N., Nagaoka T., Kuroiwa T., Akimoto H., Haku T., Kubota T., and Aso T. Histopathologic correlates of temporal diffusion changes in a rat model of cerebral hypoxia/ischemia. AJNR Am. J. Neuroradiol. 21 (2000) 60-66
15. Nedelcu J., Klein M.A., Aguzzi A., Boesiger P., and Martin E. Biphasic edema after hypoxic-ischemic brain injury in neonatal rats reflects early neuronal and late glial damage. Pediatr. Res. 46 (1999) 297-304
16. Nedelcu J., Klein M.A., Aguzzi A., and Martin E. Resuscitative hypothermia protects the neonatal rat brain from hypoxic-ischemic injury. Brain Pathol. 10 (2000) 61-71
17. Ning G., Malisza K.L., Del Bigio M.R., Bascaramurty S., Kozlowski P., and Tuor U.I. Magnetic resonance imaging during cerebral hypoxia-ischemia: T2 increases in 2-week-old but not 4-week-old rats. Pediatr. Res. 45 (1999) 173-179
18. Olah L., Wecker S., and Hoehn M. Secondary deterioration of apparent diffusion coefficient after 1 h transient focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 20 (2000) 1474-1482
19. Olah L., Wecker S., and Hoehn M. Relation of apparent diffusion coefficient changes and metabolic disturbances after 1 h of focal cerebral ischemia and at different reperfusion phases in rats. J. Cereb. Blood Flow Metab. 21 (2001) 430-439
20. Ozsunar Y., Grant P.E., Huisman T.A., Schaefer P.W., Wu O., Sorensen A.G., Koroshetz W.J., and Gonzalez R.G. Evolution of water diffusion and anisotropy in hyperacute stroke: significant correlation between fractional anisotropy and T2. AJNR Am. J. Neuroradiol. 25 (2004) 699-705
21. Park W.S., Sung D.K., Kang S., Koo S.H., Kim Y.J., Lee J.H., Chang Y.S., and Lee M. Neuroprotective effect of cycloheximide on hypoxic-ischemic brain injury in neonatal rats. J. Korean Med. Sci. 21 (2006) 337-341
22. Qiao M., Malisza K.L., Del Bigio M.R., and Tuor U.I. Correlation of cerebral hypoxic-ischemic T2 changes with tissue alterations in water content and protein extravasation. Stroke 32 (2001) 958-963
23. +-adenosine triphosphatase and cytochrome oxidase activity. Radiology 223 (2002) 65-75
24. Ringer T.M., Neumann-Haefelin T., Sobel R.A., Moseley M.E., and Yenari M.A. Reversal of early diffusion-weighted magnetic resonance imaging abnormalities does not necessarily reflect tissue salvage in experimental cerebral ischemia. Stroke 32 (2001) 2362-2369
25. Rumpel H., Buchli R., Gehrmann J., Aguzzi A., Illi O., and Martin E. Magnetic resonance imaging of brain edema in the neonatal rat: a comparison of short and long term hypoxia-ischemia. Pediatr. Res. 38 (1995) 113-118
26. Rumpel H., Nedelcu J., Aguzzi A., and Martin E. Late glial swelling after acute cerebral hypoxia-ischemia in the neonatal rat: a combined magnetic resonance and histochemical study. Pediatr. Res. 42 (1997) 54-59
27. Shen Q., Meng X., Fisher M., Sotak C.H., and Duong T.Q. Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging. J. Cereb. Blood Flow Metab. 23 (2003) 1479-1488
28. Shin D.H., Bae Y.C., Kim-Han J.S., Lee J.H., Choi I.Y., Son K.H., Kang S.S., Kim W.K., and Han B.H. Polyphenol amentoflavone affords neuroprotection against neonatal hypoxic-ischemic brain damage via multiple mechanisms. J. Neurochem. 96 (2006) 561-572
29. Tuor U.I., Kozlowski P., Del Bigio M.R., Ramjiawan B., Su S., Malisza K., and Saunders J.K. Diffusion- and T2-weighted increases in magnetic resonance images of immature brain during hypoxia-ischemia: transient reversal posthypoxia. Exp. Neurol. 150 (1998) 321-328
30. Tutak E., Satar M., Zorludemir S., Erdogan S., Yapicioglu H., and Narli N. Neuroprotective effects of indomethacin and aminoguanidine in the newborn rats with hypoxic-ischemic cerebral injury. Neurochem. Res. 30 (2005) 937-942
31. Vannucci R.C. Hypoxic-ischemic encephalopathy. Am. J. Perinatol. 17 (2000) 113-120
32. Vannucci R.C., and Vannucci S.J. Perinatal hypoxic-ischemic brain damage: evolution of an animal model. Dev. Neurosci. 27 (2005) 81-86
33. Wagner B.P., Nedelcu J., and Martin E. Delayed postischemic hypothermia improves long-term behavioral outcome after cerebral hypoxia-ischemia in neonatal rats. Pediatr. Res. 51 (2002) 354-360
34. Wang Y., Cheung P.T., Shen G.X., Wu E.X., Cao G., Bart I., Wong W.H., and Khong P.L. Hypoxic-ischemic brain injury in the neonatal rat model: relationship between lesion size at early MR imaging and irreversible infarction. AJNR Am. J. Neuroradiol. 27 (2006) 51-54
35. Xia W.J., Yang M., Fok T.F., Li K., Chan W.Y., Ng P.C., Ng H.K., Chik K.W., Wang C.C., Gu G.J., Woo K.S., and Fung K.P. Partial neuroprotective effect of pretreatment with tanshinone IIA on neonatal hypoxia-ischemia brain damage. Pediatr. Res. 58 (2005) 784-790