메뉴 건너뛰기




Volumn 360, Issue 6, 1999, Pages 609-615

Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus

Author keywords

Bilobalide; Choline; Hippocampus; Microdialysis; NMDA; Phospholipase A2

Indexed keywords

BILOBALIDE; CHOLINE; N METHYL DEXTRO ASPARTIC ACID; PHOSPHOLIPASE A2;

EID: 0033394501     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002109900131     Document Type: Article
Times cited : (113)

References (47)
  • 1
    • 0344142394 scopus 로고    scopus 로고
    • Inhibition of serum deprivation-and staurosporine-induced neuronal apoptosis by Ginkgo biloba extract and some of its constituents
    • Ahlemeyer B, Möwes A, Krieglstein J (1999) Inhibition of serum deprivation-and staurosporine-induced neuronal apoptosis by Ginkgo biloba extract and some of its constituents. Eur J Pharmacol 367:423-430
    • (1999) Eur J Pharmacol , vol.367 , pp. 423-430
    • Ahlemeyer, B.1    Möwes, A.2    Krieglstein, J.3
  • 3
    • 0024822252 scopus 로고
    • Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells
    • Barbour B, Szatkowski M, Ingledew N, Attwell D (1989) Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature 342:918-920
    • (1989) Nature , vol.342 , pp. 918-920
    • Barbour, B.1    Szatkowski, M.2    Ingledew, N.3    Attwell, D.4
  • 4
  • 5
    • 0014935332 scopus 로고
    • Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain
    • Bazan NG Jr (1970) Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain. Biochim Biophys Acta 218:1-10
    • (1970) Biochim Biophys Acta , vol.218 , pp. 1-10
    • Bazan N.G., Jr.1
  • 6
    • 0028802503 scopus 로고
    • Mediators of injury in neurotrauma: Intracellular signal transduction and gene expression
    • Bazan NG, Rodriguez De Turco EB, Allan G (1995) Mediators of injury in neurotrauma: intracellular signal transduction and gene expression. J Neurotrauma 12:791-814
    • (1995) J Neurotrauma , vol.12 , pp. 791-814
    • Bazan, N.G.1    Rodriguez De Turco, E.B.2    Allan, G.3
  • 7
    • 0024231988 scopus 로고
    • Platelet-activating factor antagonist BN52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock
    • Birkle DL, Kurian P, Braquet P, Bazan NG (1988) Platelet-activating factor antagonist BN52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock. J Neurochem 51:1900-1905
    • (1988) J Neurochem , vol.51 , pp. 1900-1905
    • Birkle, D.L.1    Kurian, P.2    Braquet, P.3    Bazan, N.G.4
  • 8
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 10
    • 0032429754 scopus 로고    scopus 로고
    • Glycine and N-methyl-D-aspartate receptors: Physiological significance and possible therapeutic applications
    • Danysz W, Parsons CG (1998) Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications. Pharmacol Rev 50:597-664
    • (1998) Pharmacol Rev , vol.50 , pp. 597-664
    • Danysz, W.1    Parsons, C.G.2
  • 12
    • 0023797159 scopus 로고
    • NMDA receptors activate the arachidonic acid cascade system in striatal neurons
    • Dumuis A, Sebben M, Haynes L, Pin J-P, Bockaert J (1988) NMDA receptors activate the arachidonic acid cascade system in striatal neurons. Nature 336:68-70
    • (1988) Nature , vol.336 , pp. 68-70
    • Dumuis, A.1    Sebben, M.2    Haynes, L.3    Pin, J.-P.4    Bockaert, J.5
  • 15
    • 0023511571 scopus 로고
    • Concomitant increases in the levels of choline and free fatty acids in rat brain: Evidence supporting the seizure-induced hydrolysis of phosphatidylcholine
    • Flynn CJ, Wecker L (1987) Concomitant increases in the levels of choline and free fatty acids in rat brain: evidence supporting the seizure-induced hydrolysis of phosphatidylcholine. J Neurochem 48:1178-1184
    • (1987) J Neurochem , vol.48 , pp. 1178-1184
    • Flynn, C.J.1    Wecker, L.2
  • 16
    • 0029016057 scopus 로고
    • Pharmacokinetic properties of bilobalide and ginkgolides A and B in healthy subjects after intravenous and oral administration of Gingko biloba extract (EGb 761)
    • Fourtillan JB, Brisson AM, Girault J, Ingrand I, Decourt JP, Drieu K, Jouenne P, Biber A (1995) Pharmacokinetic properties of Bilobalide and Ginkgolides A and B in healthy subjects after intravenous and oral administration of Gingko biloba extract (EGb 761). Thérapie 50:137-144
    • (1995) Thérapie , vol.50 , pp. 137-144
    • Fourtillan, J.B.1    Brisson, A.M.2    Girault, J.3    Ingrand, I.4    Decourt, J.P.5    Drieu, K.6    Jouenne, P.7    Biber, A.8
  • 17
    • 4243236399 scopus 로고    scopus 로고
    • Antagonistic action of bilobalide at the N-methyl-D-aspartate receptor: In vivo evidence from microdialysis experiments
    • Hilgert MW, Weichel O, Chatterjee SS, Klein J (1999) Antagonistic action of bilobalide at the N-methyl-D-aspartate receptor: in vivo evidence from microdialysis experiments. Naunyn-Schmiedeberg's Arch Pharmacol 359 [Suppl 3]:R95
    • (1999) Naunyn-Schmiedeberg's Arch Pharmacol , vol.359 , Issue.SUPPL. 3
    • Hilgert, M.W.1    Weichel, O.2    Chatterjee, S.S.3    Klein, J.4
  • 18
    • 0022544202 scopus 로고
    • Polyphosphoinositides as a probable source of brain free fatty acids accumulated at the onset of ischemia
    • Ikeda M, Yoshida S, Busto R, Santiso M, Ginsberg MD (1986) Polyphosphoinositides as a probable source of brain free fatty acids accumulated at the onset of ischemia. J Neurochem 47: 123-132
    • (1986) J Neurochem , vol.47 , pp. 123-132
    • Ikeda, M.1    Yoshida, S.2    Busto, R.3    Santiso, M.4    Ginsberg, M.D.5
  • 19
    • 0020328121 scopus 로고
    • Application to mammalian tissues of the chemiluminescent method for detecting acetylcholine
    • Israel M, Lesbats B (1982) Application to mammalian tissues of the chemiluminescent method for detecting acetylcholine. J Neurochem 39:248-250
    • (1982) J Neurochem , vol.39 , pp. 248-250
    • Israel, M.1    Lesbats, B.2
  • 20
    • 0028838803 scopus 로고
    • Protection of hypoxia-induced ATP decrease in endothelial cells by Ginkgo biloba extract and bilobalide
    • Janssens D, Michiels C, Delaive E, Fliaers F, Drieu K, Remacle J (1995) Protection of hypoxia-induced ATP decrease in endothelial cells by Ginkgo biloba extract and bilobalide. Biochem Pharmacol 50:991-999
    • (1995) Biochem Pharmacol , vol.50 , pp. 991-999
    • Janssens, D.1    Michiels, C.2    Delaive, E.3    Fliaers, F.4    Drieu, K.5    Remacle, J.6
  • 22
    • 0028009698 scopus 로고
    • Inhibition of the early phase of free fatty acid liberation during cerebral ischemia by excitatory amino acid antagonist administered by microdialysis
    • Katayama Y, Kawamata T, Maeda T, Ishikawa K, Tsubokawa T (1994) Inhibition of the early phase of free fatty acid liberation during cerebral ischemia by excitatory amino acid antagonist administered by microdialysis. Brain Res 635:331-334
    • (1994) Brain Res , vol.635 , pp. 331-334
    • Katayama, Y.1    Kawamata, T.2    Maeda, T.3    Ishikawa, K.4    Tsubokawa, T.5
  • 25
    • 0026508924 scopus 로고
    • Uptake and metabolism of choline by rat brain after acute choline administration
    • Klein J, Köppen A, Löffelholz K, Schmitthenner J (1992) Uptake and metabolism of choline by rat brain after acute choline administration. J Neurochem 58:870-876
    • (1992) J Neurochem , vol.58 , pp. 870-876
    • Klein, J.1    Köppen, A.2    Löffelholz, K.3    Schmitthenner, J.4
  • 26
    • 0027499332 scopus 로고
    • Free choline and choline metabolites in rat brain and body fluids: Sensitive determination and implications for choline supply to the brain
    • Klein J, Gonzalez R, Köppen A, Löffelholz K (1993) Free choline and choline metabolites in rat brain and body fluids: sensitive determination and implications for choline supply to the brain. Neurochem Int 22:293-300
    • (1993) Neurochem Int , vol.22 , pp. 293-300
    • Klein, J.1    Gonzalez, R.2    Köppen, A.3    Löffelholz, K.4
  • 27
    • 0030907753 scopus 로고    scopus 로고
    • Phospholipid breakdown and choline release under hypoxic conditions: Inhibition by bilobalide, a constituent of Ginkgo biloba
    • Klein J, Chatterjee SS, Löffelholz K (1997) Phospholipid breakdown and choline release under hypoxic conditions: inhibition by bilobalide, a constituent of Ginkgo biloba. Brain Res 755: 347-350
    • (1997) Brain Res , vol.755 , pp. 347-350
    • Klein, J.1    Chatterjee, S.S.2    Löffelholz, K.3
  • 28
    • 0031906593 scopus 로고    scopus 로고
    • Glutamatergic activation of hippocampal phospholipase D: Postnatal fading and receptor desensitization
    • Klein J, Vakil M, Bergman F, Holler T, Iovino M, Löffelholz K (1998) Glutamatergic activation of hippocampal phospholipase D: postnatal fading and receptor desensitization. J Neurochem 70:1679-1685
    • (1998) J Neurochem , vol.70 , pp. 1679-1685
    • Klein, J.1    Vakil, M.2    Bergman, F.3    Holler, T.4    Iovino, M.5    Löffelholz, K.6
  • 30
    • 0028944269 scopus 로고
    • N-methyl-D-aspartate-evoked release of cyclooxygenase products in rabbit hippocampus: An in vivo microdialysis study
    • Lazarewicz JW, Salinska E (1995) N-methyl-D-aspartate-evoked release of cyclooxygenase products in rabbit hippocampus: an in vivo microdialysis study. J Neurosci Res 40:660-666
    • (1995) J Neurosci Res , vol.40 , pp. 660-666
    • Lazarewicz, J.W.1    Salinska, E.2
  • 31
    • 0023933548 scopus 로고
    • Activation of N-methyl-D-aspartate-sensitive receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells
    • Lazarewicz JW, Wroblewski JT, Palmer ME, Costa E (1988) Activation of N-methyl-D-aspartate-sensitive receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells. Neuropharmacology 27:765-769
    • (1988) Neuropharmacology , vol.27 , pp. 765-769
    • Lazarewicz, J.W.1    Wroblewski, J.T.2    Palmer, M.E.3    Costa, E.4
  • 32
    • 0030770927 scopus 로고    scopus 로고
    • 2: Variation of the substituents in positions 1, 3, and 5
    • 2: variation of the substituents in positions 1, 3, and 5. J Med Chem 40:3381-3392
    • (1997) J Med Chem , vol.40 , pp. 3381-3392
    • Lehr, M.1
  • 33
    • 0343990077 scopus 로고    scopus 로고
    • Animal models of intractable epilepsy
    • Löscher W (1997) Animal models of intractable epilepsy. Prog Neurobiol 53:239-258
    • (1997) Prog Neurobiol , vol.53 , pp. 239-258
    • Löscher, W.1
  • 38
    • 0025999922 scopus 로고
    • Release of arachidonic acid by NMDA-receptor activation in the rat hippocampus
    • Pellerin L, Wolfe LS (1991) Release of arachidonic acid by NMDA-receptor activation in the rat hippocampus. Neurochem Res 16:983-989
    • (1991) Neurochem Res 16 , pp. 983-989
    • Pellerin, L.1    Wolfe, L.S.2
  • 39
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation. II. Motor seizure
    • Racine RJ (1972) Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol 32:281-294
    • (1972) Electroencephalogr Clin Neurophysiol , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 40
    • 0027435235 scopus 로고
    • Decreased electroconvulsive-shock-induced diacylglycerol and free fatty acid accumulation in the rat brain by Ginkgo biloba extract (EGb 761): Selective effect in hippocampus as compared with cerebral cortex
    • Rodriguez De Turco EB, Droy-Lefaix MT, Bazan NG (1993) Decreased electroconvulsive-shock-induced diacylglycerol and free fatty acid accumulation in the rat brain by Ginkgo biloba extract (EGb 761): selective effect in hippocampus as compared with cerebral cortex. J Neurochem 61:1438-1444
    • (1993) J Neurochem , vol.61 , pp. 1438-1444
    • Rodriguez De Turco, E.B.1    Droy-Lefaix, M.T.2    Bazan, N.G.3
  • 41
    • 0025924314 scopus 로고
    • 2) activity in gerbil brain: Enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion
    • 2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion. J Neurosci 11:1829-1836
    • (1991) J Neurosci , vol.11 , pp. 1829-1836
    • Rordorf, G.1    Uemura, Y.2    Bonventre, J.V.3
  • 42
    • 0028872674 scopus 로고
    • Excitotoxicity and the NMDA receptor: Still lethal after eight years
    • Rothman SM, Olney JW (1995) Excitotoxicity and the NMDA receptor: still lethal after eight years. Trends Neurosci 18:299-302
    • (1995) Trends Neurosci , vol.18 , pp. 299-302
    • Rothman, S.M.1    Olney, J.W.2
  • 43
    • 0025125612 scopus 로고
    • Exposure to N-methyl-D-aspartate increases release of arachidonic acid in primary cultures of rat hippocampal neurons and not in astrocytes
    • Sanfeliu C, Hunt A, Patel AJ (1990) Exposure to N-methyl-D-aspartate increases release of arachidonic acid in primary cultures of rat hippocampal neurons and not in astrocytes. Brain Res 526:241-248
    • (1990) Brain Res , vol.526 , pp. 241-248
    • Sanfeliu, C.1    Hunt, A.2    Patel, A.J.3
  • 44
    • 0025152991 scopus 로고
    • Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes
    • Santiago M, Westerink BHC (1990) Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes. Naunyn-Schmiedeberg's Arch Pharmacol 342:407-414
    • (1990) Naunyn-Schmiedeberg's Arch Pharmacol , vol.342 , pp. 407-414
    • Santiago, M.1    Westerink, B.H.C.2
  • 46
    • 0032513545 scopus 로고    scopus 로고
    • Neurodegeneration induced by reverse microdialysis of NMDA: A quantitative model for excitotoxicity in vivo
    • Vanicky I, Marsala M, Yaksh TL (1998) Neurodegeneration induced by reverse microdialysis of NMDA: a quantitative model for excitotoxicity in vivo. Brain Res 789:347-350
    • (1998) Brain Res , vol.789 , pp. 347-350
    • Vanicky, I.1    Marsala, M.2    Yaksh, T.L.3
  • 47
    • 0032525089 scopus 로고    scopus 로고
    • Region-specific and calcium-dependent increase in dialysate choline levels by NMDA
    • Zapata A, Capdevila JL, Trullas R (1998) Region-specific and calcium-dependent increase in dialysate choline levels by NMDA. J Neurosci 18:3597-3605
    • (1998) J Neurosci , vol.18 , pp. 3597-3605
    • Zapata, A.1    Capdevila, J.L.2    Trullas, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.