Self-induced docking site of a deeply embedded peripheral membrane protein

Biophysical Journal

Volumn 92, Issue 2, 2007, Pages 517-524

  Jaud, Simon ^a   Tobias, Douglas J ^a   Falke, Joseph J ^c   White, Stephen H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 PALMITOYL 2 OLEOYL PHOSPHATIDYLCHOLINE; CALCIUM ION; MEMBRANE PROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

ARTICLE; BILAYER MEMBRANE; CALCIUM BINDING; CRYSTAL STRUCTURE; ELECTRON SPIN RESONANCE; MOLECULAR DYNAMICS; SIMULATION;

EID: 33846451059     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.106.090704     Document Type: Article

References (31)

1. Leslie, C. C. 2004. Regulation of the specific release of arachidonic acid by cytosolic phospholipase A2. Prostaglandins Leukot. Essent. Fatty Acids. 70:373-376.
2. Clark, J. D., A. R. Schievella, E. A. Nalefski, and L.-L. Lin. 1995. Cytosolic phospholipase A2. J. Lipid Mediat. Cell Signal. 12:83-117.
3. Dessen, A., J. Tang, H. Schmidt, M. Stahl, J. D. Clark, J. Seehra, and W. S. Somers. 1999. Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism. Cell. 97:349-360.
4. Cho, W., and R. V. Stahelin. 2005. Membrane-protein interactions in cell signaling and membrane trafficking. Annu. Rev. Biophys. Biomol. Struct. 34:119-151.
5. Bai, J., and E. R. Chapman. 2004. The C2 domains of synaptotagmin - partners in exocytosis. Trends Biochem. Sci. 29:143-151.
6. Hurley, J. H., and S. Misra. 2000. Signaling and subcellular targeting by membrane-binding domains. Annu. Rev. Biophys. Biomol. Struct. 29:49-79.
7. Rizo, J., and T. C. Südhof. 1998. C2-domains, structure and function of a universal Ca2+-binding domain. J. Biol. Chem. 273:15879-15882.
8. Nalefski, E. A., M. M. Slazas, and J. J. Falke. 1997. Ca2+-signaling cycle of a membrane-docking C2 domain. Biochemistry. 36:12011-12018.
9. Perisic, O., S. Fong, D. E. Lynch, M. Bycroft, and R. L. Williams. 1998. Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2. J. Biol. Chem. 273:1596-1604.
10. 2. J. Mol. Biol. 280:485-500.
11. Perisic, O., H. F. Paterson, G. Mosedale, S. Lara-González, and R. L. Williams. 1999. Mapping the phospholipid-binding surface and translocation determinants of the C2 domain from cytosolic phospholipase A2. J. Biol. Chem. 274:14979-14987.
12. 2+ signaling pathways display functional and mechanistic diversity. Biochemistry. 40:3089-3100.
13. 2+-activated C2 domain of cytosoic phospholipase A2. Biochemistry. 37:17642-17650.
14. Frazier, A. A., M. A. Wisner, N. J. Malmberg, K. G. Victor, G. E. Fanucci, E. A. Nalefski, J. J. Falke, and D. S. Cafiso. 2002. Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry. 41:6282-6292.
15. Nielsen, R. D., K. Che, M. H. Gelb, and B. H. Robinson. 2005. A ruler for determining the position of proteins in membranes. J. Am. Chem. Soc. 127:6430-6442.
16. Malmberg, N. J., D. R. Van Buskirk, and J. J. Falke. 2003. Membrane-docking loops of the cPLA2 C2 domain: Detailed structural analysis of the protein-membrane interface via site-directed spin-labeling. Biochemistry. 42:13227-13240.
17. Málková, S., F. Long, R. V. Stahelin, S. V. Pingali, D. Murray, W. Cho, and M. L. Schlossman. 2005. X-ray reflectivity studies of cPLA2α-C2 domains adsorbed onto Langmuir monolayers of SOPC. Biophys. J. 89:1861-1873.
18. Freites, J. A., D. J. Tobias, G. von Heijne, and S. H. White. 2005. Interface connections of a transmembrane voltage sensor. Proc. Natl. Acad. Sci. USA. 102:15059-15064.
19. Tuckerman, M., and B. J. Berne. 1992. Reversible multiple time scale molecular dynamics. J. Chem. Phys. 97:1990-2001.
20. Grubmüller, H., H. Heller, A. Windemuth, and K. Schulten. 1991. Generalized Verlet algorithm for efficient molecular dynamics simulations with long-range interactions. Mol. Simul. 6:121-142.
21. Ryckaert, J.-P., G. Ciccotti, and H. J. C. Berendsen. 1977. Numerical integration of the Cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes. J. Comput. Phys. 23:327-341.
22. Darden, T., D. York, and L. Pedersen. 1993. Particle mesh Ewald: An N·log(N) method for Ewald sums in large systems. J. Chem. Phys. 98:10089-10092.
23. Martyna, G. J., D. J. Tobias, and M. L. Klein. 1994. Constant-pressure molecular-dynamics algorithms. J. Chem. Phys. 101:4177-4189.
24. Feller, S. E., Y. Zhang, R. W. Pastor, and B. R. Brooks. 1995. Constant pressure molecular dynamics simulation: the Langevin piston method. J. Chem. Phys. 103:4613-4621.
25. Kalé, L., R. Skeel, M. Bhandarkar, R. Brunner, A. Gursoy, N. Krawetz, J. Phillips, A. Shinozaki, K. Varadarajan, and K. Schulten. 1999. NAMD2: Greater scalability for parallel molecular dynamics. J. Comput. Phys. 151:283-312.
26. MacKerell, A. D. Jr., D. Bashford, M. Bellott, R. L. Dunbrack Jr., J. D. Evanseck, M. J. Field, S. Fischer, J. Gao, H. Guo, S. Ha, D. Joseph-McCarthy, L. Kuchnir, et al. 1998. All-atom empirical potential for molecular modeling and dynamics studies of proteins. J. Phys. Chem. B. 102:3586-3616.
27. Feller, S. E., and A. D. MacKerell Jr. 2000. An improved empirical potential energy function for molecular simulations of phospholipids. J. Phys. Chem. B. 104:7510-7515.
28. Murray, D., and B. Honig. 2002. Electrostatic control of the membrane targeting of C2 domains. Mol. Cell. 9:145-154.
29. Wiener, M. C., and S. H. White. 1992. Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. III. Complete structure. Biophys. J. 61:434-447.
30. Humphrey, W., W. Dalke, and K. Schulten. 1996. VMD: visual molecular dynamics. J. Mol. Graph. 14:33-38.
31. Flyvbjerg, H., and H. G. Petersen. 1989. Error estimates on averages of correlated data. J. Chem. Phys. 91:461-466.