A novel azaindolizinone derivative ZSET1446 (spiro[imidazo[1,2-a]pyridine- 3,2-indan]-2(3H)-one) improves methamphetamine-induced impairment of recognition memory in mice by activating extracellular signal-regulated kinase 1/2

Journal of Pharmacology and Experimental Therapeutics

Volumn 320, Issue 2, 2007, Pages 819-827

  Ito, Yukio ^a   Takuma, Kazuhiro ^a   Mizoguchi, Hiroyuki ^a   Nagai, Taku ^a   Yamada, Kiyofumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALPHA [AMINO (4 AMINOPHENYLTHIO)METHYLENE] 2 (TRIFLUOROMETHYL)PHENYLACETONITRILE; DIZOCILPINE; DIZOCILPINE MALEATE; INDOLIZINE DERIVATIVE; METHAMPHETAMINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RACLOPRIDE; SL 327; SPIRO[IMIDAZO[1,2 A]PYRIDINE 3,2 INDAN] 2 (3H) ONE; UNCLASSIFIED DRUG; ZSET 1446;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; MALE; MEMORY DISORDER; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RECOGNITION;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; COGNITION; DIZOCILPINE MALEATE; ENZYME ACTIVATION; INDANS; LONG-TERM POTENTIATION; MALE; METHAMPHETAMINE; MICE; MICE, INBRED ICR; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PREFRONTAL CORTEX; SPIRO COMPOUNDS;

EID: 33846446398     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.114108     Document Type: Article

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