Clozapine preferentially increases dopamine release in the rhesus monkey prefrontal cortex compared with the caudate nucleus

Neuropsychopharmacology

Volumn 20, Issue 5, 1999, Pages 403-412

  Youngren, Kenneth D ^a   Inglis, Fiona M ^a   Pivirotto, Philip J ^a   Jedema, Hank P ^a   Bradberry, Charles W ^a   Goldman Rakic, Patricia S ^a   Roth, Robert H ^a   Moghaddam, Bita ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antipsychotic drugs; Haloperidol; Microdialysis; Schizophrenia; Striatum

Indexed keywords

CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINE RELEASE; MICRODIALYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; RHESUS MONKEY; SCHIZOPHRENIA;

ANIMALS; ANTIPSYCHOTIC AGENTS; CAUDATE NUCLEUS; CLOZAPINE; DOPAMINE; DOPAMINE ANTAGONISTS; EXTRACELLULAR SPACE; HALOPERIDOL; MACACA MULATTA; MAGNETIC RESONANCE IMAGING; MALE; MICRODIALYSIS; NEUROTRANSMITTER AGENTS; PREFRONTAL CORTEX;

EID: 0033136167     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(98)00082-7     Document Type: Article

References (38)

1. Ashby C.R. Jr., Wang R.Y. Pharmacological actions of the atypical antipsychotic drug clozapine. a review Synapse. 24:1996;349-394.
2. Berger B., Casper P., Verney C. Dopaminergic innervation of the cerebral cortex. unexpected differences between rodents and primates TINS. 14:1991;21-27.
3. Bourdelais A.J., Deutch A.Y. The effects of haloperidol and clozapine on extracellular GABA levels in the prefrontal cortex of the rat. an in vivo microdialysis study Cereb Cortex. 4:1994;69-77.
4. Creese I., Burt D.R., Snyder S.H. Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity. Science. 197:1977;596-598.
5. Daly D.A., Moghaddam B. Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats. Neurosci Lett. 152:1993;61-64.
6. Davis K.L., Kahn R.S., Ko G., Davidson M. Dopamine in schizophrenia. a review and reconceptualization Am J Psychiatry. 148:1991;1474-1486.
7. Jakab R.L., Goldman-Rakic P.S. 5-hydroxytryptamine(2A) serotonin receptors in the primate cerebral cortex - possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites. Proc Natl Acad Sci. 95:1998;735-740.
8. Jentsch J.D., Redmond Jr D.E., Elsworth J.D., Taylor J.R., Youngren K.D., Roth R.H. Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine. Science. 277:1997;953-955.
9. Kane J., Honigfeld G., Singer J., Meltzer H. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch Gen Psychiatry. 45:1988;789-796.
10. Kane J.M., Woerner M.G., Pollack S., Safferman A.Z., Lieberman J.A. Does clozapine cause tardive dyskinesia? J Clin Psychiatry. 54:1993;327-330.
11. Karreman M., Moghaddam B. The prefrontal cortex regulates the basal release of dopamine in the limbic striatum. an effect mediated by ventral tegmental area J Neurochem. 66:1996;589-598.
12. Kolachana B.S., Saunders R.C., Weinberger D.R. An improved methodology for routine in vivo microdialysis in non-human primates. J Neurosci Methods. 55:1994;1-6.
13. Kolachana B.S., Saunders R.C., Weinberger D.R. Augmentation of prefrontal cortical monoaminergic activity inhibits dopamine release in the caudate nucleus. an in vivo neurochemical assessment in the rhesus monkey Neuroscience. 69:1995;859-868.
14. Lee M.A., Thompson P.A., Meltzer H.Y. Effects of clozapine on cognitive function in schizophrenia. J Clin Psychiatry. 55:1994;82-87.
15. Lidow M.S., Elsworth J., Goldman-Rakic P.S. Down-regulation of the D1 and D5 dopamine receptors in the primate prefrontal cortex by chronic treatment with antipsychotic drugs. J Pharmacol Exp Ther. 281:1997;597-603.
16. Lidow M.S., Goldman-Rakic P.S. A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex. Proc Natl Acad Sci USA. 91:1994;4353-4356.
17. Machida C.A., Searles R.P., Nipper V., Brown J.A., Kozell L.B., Neve K.A. Molecular cloning and expression of the rhesus macaque D1 dopamine receptor gene. Mol Pharmacol. 41:1992;652-659.
18. Moghaddam B., Berridge C.W., Goldman-Rakic P.S., Bunney B.S., Roth R.H. In vivo assessment of basal and drug-induced dopamine release in cortical and subcortical regions of the anesthetized primate. Synapse. 13:1993;215-222.
19. Moghaddam B., Bunney B.S. Acute effects of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens, and striatum of the rat. an in vivo microdialysis study J Neurochem. 54:1990;1755-1760.
20. Mrzljak L., Bergson C., Pappy M., Huff R., Levenson R., Goldman-Rakic P.S. Localization of dopamine D4 receptors in GABAergic neurons of the primate brain. Nature. 381:1996;245-248.
21. Pehek E.A. Local infusion of the serotonin antagonists ritanserin or ICS 205,930 increases in vivo dopamine release in the rat medial prefrontal cortex. Synapse. 24:1996;12-18.
22. Pehek E.A., Meltzer H.Y., Yamamoto B.K. The atypical antipsychotic drug amperozide enhances rat cortical and striatal dopamine efflux. Eur J Pharmacol. 240:1993;107-109.
23. Preuss T.M., Goldman-Rakic P.S. Ipsilateral cortical connections of granular frontal cortex in the strepsirhine primate Galago, with comparative comments on anthropoid primates. J Comp Neurol. 310:1991;507-549.
24. 1a agonist ±8-OH-DPAT modulates basal and stress-induced changes in medial prefrontal cortical dopamine. Synapse. 18:1994;218-224.
25. Rollema H., Lu Y., Schmidt A.W., Zorn S.H. Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation. Eur J Pharmacol. 338:1997;R3-R5.
26. Saunders R.C., Kolachana B.S., Bachevalier J., Weinberger D.R. Neonatal lesions of the medial temporal lobe disrupt prefrontal cortical regulation of striatal dopamine. Nature. 393:1998;169-171.
27. Schmidt C.J., Fadayel G.M. The selective 5-HT2A receptor antagonist, MDL 100,907, increases dopamine efflux in the prefrontal cortex of the rat. Eur J Pharmacol. 273:1995;273-279.
28. Seeman P., Lee T., Chau-Wong M., Tedesco J., Wong K. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature. 261:1976;717-719.
29. Seeman P. Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4. Neuropsychopharmacol. 7:1992;261-284.
30. Taber M.T., Das S., Fibiger H.C. Cortical regulation of subcortical dopamine release. mediation via the ventral tegmental area J Neurochem. 65:1995;1407-1410.
31. Uylings HBM, van Eden CG (1990): Qualitative and quantitative comparison of the prefrontal cortex in rat and in primates, including humans. In Uylings HBM, van Eden CG, De Bruin JPC, Corner MA, Feenstra MGP (eds), Progress in Brain Research, Vol 85. Amsterdam: Elsevier, pp 31-62.
32. van Tol H.H., Bunzow J.R., Guan H.-C., Sunahara R.K., Seeman P., Niznik H.B., Civelli O. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature. 350:1991;610-614.
33. Wang J., Skirboll S., Aigner T.G., Saunders R.C., Hsiao J., Bankiewicz K.S. Methodology of microdialysis of neostriatum in hemiparkinsonian nonhuman primates. Exp Neurol. 110:1990;181-186.
34. Weinberger D.R., Berman K.F., Zec R.F. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry. 43:1986;114-124.
35. Williams GV, Rao SG, Franowitz M, Romanski L, Goldman-Rakic PS (1996): Ritanserin reduces activity of prefrontal pyramidal neurons recorded during working memory tasks. Soc Neurosci Abstr 22:1936.
36. Williams S.M., Goldman-Rakic P.S. Characterization of the dopaminergic innervation of the primate frontal cortex using a dopamine-specific antibody. Cereb Cortex. 3:1993;199-222.
37. Yamamoto B.K., Cooperman M.A. Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations. J Neurosci. 14:1994;4159-4166.
38. Youngren K.D., Moghaddam B., Bunney B.S., Roth R.H. Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment. Neurosci Lett. 165:1994;41-44.