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Volumn 53, Issue 1, 2007, Pages 59-69

Effect of rapamycin on hepatocyte function and proliferation induced by growth factors

Author keywords

Albumin; Fibrinogen; Hepatocyte growth factor; Rapamycin; Transforming growth factor ; Wortmannin

Indexed keywords

ALBUMIN; DNA; FIBRINOGEN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RAPAMYCIN; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; WORTMANNIN;

EID: 33846435319     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000098420     Document Type: Article
Times cited : (5)

References (43)
  • 1
    • 0016724057 scopus 로고
    • Rapamycin (AY-22,989), a new antifungal antibiotic. 1. Taxonomy of the producing streptomycete and isolation of the active principle
    • Vezina C, Kudelski A, Sehgal SN: Rapamycin (AY-22,989), a new antifungal antibiotic. 1. Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot 1975;28:721-726.
    • (1975) J Antibiot , vol.28 , pp. 721-726
    • Vezina, C.1    Kudelski, A.2    Sehgal, S.N.3
  • 2
    • 0016713286 scopus 로고
    • Rapamycin (AY-22,989), a new antifungal antibiotic. 2. Fermentation, isolation and characterization
    • Sehgal SN, Baker H, Vezina C: Rapamycin (AY-22,989), a new antifungal antibiotic. 2. Fermentation, isolation and characterization. J Antibiot 1975;28:727-732.
    • (1975) J Antibiot , vol.28 , pp. 727-732
    • Sehgal, S.N.1    Baker, H.2    Vezina, C.3
  • 3
    • 2342545519 scopus 로고    scopus 로고
    • Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
    • Fingar DC, Blenis J: Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 2004;23:3151-3171.
    • (2004) Oncogene , vol.23 , pp. 3151-3171
    • Fingar, D.C.1    Blenis, J.2
  • 4
    • 8344281974 scopus 로고    scopus 로고
    • Targeting the molecular target of rapamycin (mTOR)
    • Rowinsky EK: Targeting the molecular target of rapamycin (mTOR). Curr Opin Oncol 2004;16:564-575.
    • (2004) Curr Opin Oncol , vol.16 , pp. 564-575
    • Rowinsky, E.K.1
  • 5
    • 0037468694 scopus 로고    scopus 로고
    • New immunosuppressive agent: Expectations and controversies
    • Alsina J, Grinyo JM: New immunosuppressive agent: expectations and controversies. Transplantation 2003;75:741-742.
    • (2003) Transplantation , vol.75 , pp. 741-742
    • Alsina, J.1    Grinyo, J.M.2
  • 6
    • 7944223834 scopus 로고    scopus 로고
    • Targeting the mammalian target of rapamycin (mTOR): A new approach to treating cancer
    • Chan S: Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer. Br J Cancer 2004;91:1420-1424.
    • (2004) Br J Cancer , vol.91 , pp. 1420-1424
    • Chan, S.1
  • 8
    • 0037207525 scopus 로고    scopus 로고
    • Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin
    • Decker T, Hipp S, Ringshausen I, Bogner C, Oelsner M, Schneller F, Peschel C: Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin. Blood 2003;101:278-285.
    • (2003) Blood , vol.101 , pp. 278-285
    • Decker, T.1    Hipp, S.2    Ringshausen, I.3    Bogner, C.4    Oelsner, M.5    Schneller, F.6    Peschel, C.7
  • 9
    • 7044262774 scopus 로고    scopus 로고
    • Drug-eluting stents: A mechanical and pharmacologic approach to coronary artery disease
    • Dobesh PP, Stacy ZA, Ansara AJ, Enders JM: Drug-eluting stents: a mechanical and pharmacologic approach to coronary artery disease. Pharmacotherapy 2004;24:1554-1577.
    • (2004) Pharmacotherapy , vol.24 , pp. 1554-1577
    • Dobesh, P.P.1    Stacy, Z.A.2    Ansara, A.J.3    Enders, J.M.4
  • 10
    • 3042797865 scopus 로고    scopus 로고
    • Novel approaches to reduce restenosis
    • Beyar R: Novel approaches to reduce restenosis. Ann N Y Acad Sci 2004;1015:367-378.
    • (2004) Ann N Y Acad Sci , vol.1015 , pp. 367-378
    • Beyar, R.1
  • 11
    • 0001925425 scopus 로고    scopus 로고
    • Hepatic regeneration; in Zakim D, Boyer TD (eds): Hepatology
    • ed 3. Philadelphia, Saunders
    • Fausto N: Hepatic regeneration; in Zakim D, Boyer TD (eds): Hepatology. A Text Book of Liver Disease, ed 3. Philadelphia, Saunders, 1996, pp 32-58.
    • (1996) A Text Book of Liver Disease , pp. 32-58
    • Fausto, N.1
  • 13
    • 0035179267 scopus 로고    scopus 로고
    • Influence of antiestrogens on NIH-3T3-fibroblast-induced motility of breast cancer cells
    • Rajah TT, Rambo DJ, Dmytryk JJ, Pento JT: Influence of antiestrogens on NIH-3T3-fibroblast-induced motility of breast cancer cells. Chemotherapy 2001;47:56-69.
    • (2001) Chemotherapy , vol.47 , pp. 56-69
    • Rajah, T.T.1    Rambo, D.J.2    Dmytryk, J.J.3    Pento, J.T.4
  • 15
    • 0022550757 scopus 로고
    • Transcriptional switch from albumin to alpha-fetoprotein and changes in transcription of other genes during carbon tetrachloride induced liver regeneration
    • Panduro A, Shalaby F, Weiner FR, Biempica L, Zern MA, Shafritz DA: Transcriptional switch from albumin to alpha-fetoprotein and changes in transcription of other genes during carbon tetrachloride induced liver regeneration. Biochemistry 1986;25:1414-1420.
    • (1986) Biochemistry , vol.25 , pp. 1414-1420
    • Panduro, A.1    Shalaby, F.2    Weiner, F.R.3    Biempica, L.4    Zern, M.A.5    Shafritz, D.A.6
  • 16
    • 0031883558 scopus 로고    scopus 로고
    • Enhancement of albumin production by hepatocyte growth factor in rat hepatocytes: Distinction in mode of action from stimulation of DNA synthesis
    • Yamaoka M, Hirata K, Ogata I, Tomiya T, Nagoshi S, Mochida S, Fujiwara K: Enhancement of albumin production by hepatocyte growth factor in rat hepatocytes: distinction in mode of action from stimulation of DNA synthesis. Liver 1998;18:52-59.
    • (1998) Liver , vol.18 , pp. 52-59
    • Yamaoka, M.1    Hirata, K.2    Ogata, I.3    Tomiya, T.4    Nagoshi, S.5    Mochida, S.6    Fujiwara, K.7
  • 17
    • 0026792940 scopus 로고
    • Cell density-dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor
    • Takehara T, Matsumoto K, Nakamura T: Cell density-dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor. J Biochem 1992;112:330-334.
    • (1992) J Biochem , vol.112 , pp. 330-334
    • Takehara, T.1    Matsumoto, K.2    Nakamura, T.3
  • 18
    • 0026484294 scopus 로고
    • Direct evidence that hepatocyte growth factor is a hepatotropic factor for liver regeneration and has a potent antihepatitis effect in vivo
    • Ishiki Y, Ohnishi H, Muto Y, Matsumoto K, Nakamura T: Direct evidence that hepatocyte growth factor is a hepatotropic factor for liver regeneration and has a potent antihepatitis effect in vivo. Hepatology 1992;16:1227-1235.
    • (1992) Hepatology , vol.16 , pp. 1227-1235
    • Ishiki, Y.1    Ohnishi, H.2    Muto, Y.3    Matsumoto, K.4    Nakamura, T.5
  • 20
    • 0028040336 scopus 로고
    • In vivo response of hepatocytes to growth factors requires an initial priming stimulus
    • Webber EM, Godowski PJ, Fausto N: In vivo response of hepatocytes to growth factors requires an initial priming stimulus. Hepatology 1994;19:489-497.
    • (1994) Hepatology , vol.19 , pp. 489-497
    • Webber, E.M.1    Godowski, P.J.2    Fausto, N.3
  • 21
    • 0041531109 scopus 로고
    • Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism
    • Mead JE, Fausto N: Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc Natl Acad Sci USA 1989;86:1558-1562.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1558-1562
    • Mead, J.E.1    Fausto, N.2
  • 23
    • 0027331503 scopus 로고
    • Transforming growth factor-alpha expression during liver regeneration after partial hepatectomy and toxic injury, and potential interactions between transforming growth factor-alpha and hepatocyte growth factor
    • Webber EM, FitzGerald MJ, Brown PI, Bartlett MH, Fausto N: Transforming growth factor-alpha expression during liver regeneration after partial hepatectomy and toxic injury, and potential interactions between transforming growth factor-alpha and hepatocyte growth factor. Hepatology 1993;18:1422-1431.
    • (1993) Hepatology , vol.18 , pp. 1422-1431
    • Webber, E.M.1    FitzGerald, M.J.2    Brown, P.I.3    Bartlett, M.H.4    Fausto, N.5
  • 24
    • 0031685201 scopus 로고    scopus 로고
    • Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration
    • Tomiya T, Ogata I, Fujiwara K: Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration. Am J Pathol 1998;153:955-961.
    • (1998) Am J Pathol , vol.153 , pp. 955-961
    • Tomiya, T.1    Ogata, I.2    Fujiwara, K.3
  • 25
    • 0026712354 scopus 로고
    • Serum hepatocyte growth factor levels in hepatectomized and nonhepatectomized surgical patients
    • Tomiya T, Tani M, Yamada S, Hayashi S, Umeda N, Fujiwara K: Serum hepatocyte growth factor levels in hepatectomized and nonhepatectomized surgical patients. Gastroenterology 1992;103:1621-1624.
    • (1992) Gastroenterology , vol.103 , pp. 1621-1624
    • Tomiya, T.1    Tani, M.2    Yamada, S.3    Hayashi, S.4    Umeda, N.5    Fujiwara, K.6
  • 26
    • 0026601033 scopus 로고
    • Significance of serum human hepatocyte growth factor levels in patients with hepatic failure
    • Tomiya T, Nagoshi S, Fujiwara K: Significance of serum human hepatocyte growth factor levels in patients with hepatic failure. Hepatology 1992;15:1-4.
    • (1992) Hepatology , vol.15 , pp. 1-4
    • Tomiya, T.1    Nagoshi, S.2    Fujiwara, K.3
  • 27
    • 0027218227 scopus 로고
    • Serum levels of transforming growth factor-alpha in patients after partial hepatectomy as determined with an enzyme-linked immunosorbent assay
    • Tomiya T, Fujiwara K: Serum levels of transforming growth factor-alpha in patients after partial hepatectomy as determined with an enzyme-linked immunosorbent assay. Hepatology 1993;18:304-308.
    • (1993) Hepatology , vol.18 , pp. 304-308
    • Tomiya, T.1    Fujiwara, K.2
  • 28
    • 0030939743 scopus 로고    scopus 로고
    • Serum transforming growth factor alpha level can be a parameter for evaluating liver regeneration after partial hepatectomy in patients with liver cancer
    • Tomiya T, Hayashi S, Yanase M, Umeda N, Tani M, Yamada S, Masaki N, Ogata I, Fujiwara K: Serum transforming growth factor alpha level can be a parameter for evaluating liver regeneration after partial hepatectomy in patients with liver cancer. Semin Oncol 1997;24:14-17.
    • (1997) Semin Oncol , vol.24 , pp. 14-17
    • Tomiya, T.1    Hayashi, S.2    Yanase, M.3    Umeda, N.4    Tani, M.5    Yamada, S.6    Masaki, N.7    Ogata, I.8    Fujiwara, K.9
  • 29
    • 0030042425 scopus 로고    scopus 로고
    • Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor alpha levels
    • Tomiya T, Fujiwara K: Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor alpha levels. Hepatology 1996;23:253-257.
    • (1996) Hepatology , vol.23 , pp. 253-257
    • Tomiya, T.1    Fujiwara, K.2
  • 30
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen PO: Preparation of isolated rat liver cells. Methods Cell Biol 1976;13:29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 31
    • 27544495547 scopus 로고    scopus 로고
    • Effect of the farnesyl transferase inhibitor L-744,832 on the colon cancer cell line DLD-1 and its combined use with radiation and 5-FU
    • Kavgaci H, Ozdemir F, Ovali E, Yavuz A, Yavuz M, Aydin F: Effect of the farnesyl transferase inhibitor L-744,832 on the colon cancer cell line DLD-1 and its combined use with radiation and 5-FU. Chemotherapy 2005;51:319-323.
    • (2005) Chemotherapy , vol.51 , pp. 319-323
    • Kavgaci, H.1    Ozdemir, F.2    Ovali, E.3    Yavuz, A.4    Yavuz, M.5    Aydin, F.6
  • 32
    • 0025787867 scopus 로고
    • Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: Cloning of its cDNA, purification and characterization of recombinant protein
    • Shima N, Nagao M, Ogaki F, Tsuda E, Murakami A, Higashio K: Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: cloning of its cDNA, purification and characterization of recombinant protein. Biochem Biophys Res Commun 1991;180:1151-1158.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 1151-1158
    • Shima, N.1    Nagao, M.2    Ogaki, F.3    Tsuda, E.4    Murakami, A.5    Higashio, K.6
  • 35
    • 0029905271 scopus 로고    scopus 로고
    • The hepatocyte growth factor regulates the synthesis of acute-phase proteins in human hepatocytes: Divergent effect on interleukin-6-stimulated genes
    • Guillen MI, Gomez-Lechon MJ, Nakamura T, Castell JV: The hepatocyte growth factor regulates the synthesis of acute-phase proteins in human hepatocytes: divergent effect on interleukin-6-stimulated genes. Hepatology 1996;23:1345-1352.
    • (1996) Hepatology , vol.23 , pp. 1345-1352
    • Guillen, M.I.1    Gomez-Lechon, M.J.2    Nakamura, T.3    Castell, J.V.4
  • 36
    • 0020285970 scopus 로고
    • Synthesis and secretion of plasma proteins by isolated hepatocytes of analbuminemic rats
    • Sugiyama K, Emori T, Nagase S: Synthesis and secretion of plasma proteins by isolated hepatocytes of analbuminemic rats. J Biochem 1982;92:775-779.
    • (1982) J Biochem , vol.92 , pp. 775-779
    • Sugiyama, K.1    Emori, T.2    Nagase, S.3
  • 37
    • 0034968334 scopus 로고    scopus 로고
    • Transcriptional control mechanism of fibrinogen gene expression
    • Fuller GM, Zhang Z: Transcriptional control mechanism of fibrinogen gene expression. Ann N Y Acad Sci 2001;936:469-479.
    • (2001) Ann N Y Acad Sci , vol.936 , pp. 469-479
    • Fuller, G.M.1    Zhang, Z.2
  • 38
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
    • Chung J, Kuo CJ, Crabtree GR, Blenis J: Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 1992;69:1227-1236.
    • (1992) Cell , vol.69 , pp. 1227-1236
    • Chung, J.1    Kuo, C.J.2    Crabtree, G.R.3    Blenis, J.4
  • 39
    • 0036440779 scopus 로고    scopus 로고
    • Regulation of mammalian translation factors by nutrients
    • Proud CG: Regulation of mammalian translation factors by nutrients. Eur J Biochem 2002;269:5338-5349.
    • (2002) Eur J Biochem , vol.269 , pp. 5338-5349
    • Proud, C.G.1
  • 40
    • 0346996344 scopus 로고    scopus 로고
    • Regulation of global and specific mRNA translation by oral administration of branched-chain amino acids
    • Kimball SR, Jefferson LS: Regulation of global and specific mRNA translation by oral administration of branched-chain amino acids. Biochem Biophys Res Commun 2004;313:423-427.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 423-427
    • Kimball, S.R.1    Jefferson, L.S.2
  • 41
    • 0347627142 scopus 로고    scopus 로고
    • Regulation of protein synthesis by branched-chain amino acids in vivo
    • Yoshizawa F: Regulation of protein synthesis by branched-chain amino acids in vivo. Biochem Biophys Res Commun 2004;313:417-422.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 417-422
    • Yoshizawa, F.1
  • 42
    • 0032054816 scopus 로고    scopus 로고
    • The mRNA 5′ cap-binding protein eIF4E and control of cell growth
    • Sonenberg N, Gingras AC: The mRNA 5′ cap-binding protein eIF4E and control of cell growth. Curr Opin Cell Biol 1998;10:268-275.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 268-275
    • Sonenberg, N.1    Gingras, A.C.2
  • 43
    • 0029118603 scopus 로고
    • Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
    • Ui M, Okada T, Hazeki K, Hazeki O: Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 1995;20:303-307.
    • (1995) Trends Biochem Sci , vol.20 , pp. 303-307
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4


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