-
1
-
-
0016724057
-
Rapamycin (AY-22,989), a new antifungal antibiotic. 1. Taxonomy of the producing streptomycete and isolation of the active principle
-
Vezina C, Kudelski A, Sehgal SN: Rapamycin (AY-22,989), a new antifungal antibiotic. 1. Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot 1975;28:721-726.
-
(1975)
J Antibiot
, vol.28
, pp. 721-726
-
-
Vezina, C.1
Kudelski, A.2
Sehgal, S.N.3
-
2
-
-
0016713286
-
Rapamycin (AY-22,989), a new antifungal antibiotic. 2. Fermentation, isolation and characterization
-
Sehgal SN, Baker H, Vezina C: Rapamycin (AY-22,989), a new antifungal antibiotic. 2. Fermentation, isolation and characterization. J Antibiot 1975;28:727-732.
-
(1975)
J Antibiot
, vol.28
, pp. 727-732
-
-
Sehgal, S.N.1
Baker, H.2
Vezina, C.3
-
3
-
-
2342545519
-
Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
-
Fingar DC, Blenis J: Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 2004;23:3151-3171.
-
(2004)
Oncogene
, vol.23
, pp. 3151-3171
-
-
Fingar, D.C.1
Blenis, J.2
-
4
-
-
8344281974
-
Targeting the molecular target of rapamycin (mTOR)
-
Rowinsky EK: Targeting the molecular target of rapamycin (mTOR). Curr Opin Oncol 2004;16:564-575.
-
(2004)
Curr Opin Oncol
, vol.16
, pp. 564-575
-
-
Rowinsky, E.K.1
-
5
-
-
0037468694
-
New immunosuppressive agent: Expectations and controversies
-
Alsina J, Grinyo JM: New immunosuppressive agent: expectations and controversies. Transplantation 2003;75:741-742.
-
(2003)
Transplantation
, vol.75
, pp. 741-742
-
-
Alsina, J.1
Grinyo, J.M.2
-
6
-
-
7944223834
-
Targeting the mammalian target of rapamycin (mTOR): A new approach to treating cancer
-
Chan S: Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer. Br J Cancer 2004;91:1420-1424.
-
(2004)
Br J Cancer
, vol.91
, pp. 1420-1424
-
-
Chan, S.1
-
7
-
-
17444440115
-
Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone
-
Stromberg T, Dimberg A, Hammarberg A, Carlson K, Osterborg A, Nilsson K, Jernberg-Wiklund H: Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone. Blood 2004;103:3138-3147.
-
(2004)
Blood
, vol.103
, pp. 3138-3147
-
-
Stromberg, T.1
Dimberg, A.2
Hammarberg, A.3
Carlson, K.4
Osterborg, A.5
Nilsson, K.6
Jernberg-Wiklund, H.7
-
8
-
-
0037207525
-
Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin
-
Decker T, Hipp S, Ringshausen I, Bogner C, Oelsner M, Schneller F, Peschel C: Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin. Blood 2003;101:278-285.
-
(2003)
Blood
, vol.101
, pp. 278-285
-
-
Decker, T.1
Hipp, S.2
Ringshausen, I.3
Bogner, C.4
Oelsner, M.5
Schneller, F.6
Peschel, C.7
-
9
-
-
7044262774
-
Drug-eluting stents: A mechanical and pharmacologic approach to coronary artery disease
-
Dobesh PP, Stacy ZA, Ansara AJ, Enders JM: Drug-eluting stents: a mechanical and pharmacologic approach to coronary artery disease. Pharmacotherapy 2004;24:1554-1577.
-
(2004)
Pharmacotherapy
, vol.24
, pp. 1554-1577
-
-
Dobesh, P.P.1
Stacy, Z.A.2
Ansara, A.J.3
Enders, J.M.4
-
10
-
-
3042797865
-
Novel approaches to reduce restenosis
-
Beyar R: Novel approaches to reduce restenosis. Ann N Y Acad Sci 2004;1015:367-378.
-
(2004)
Ann N Y Acad Sci
, vol.1015
, pp. 367-378
-
-
Beyar, R.1
-
11
-
-
0001925425
-
Hepatic regeneration; in Zakim D, Boyer TD (eds): Hepatology
-
ed 3. Philadelphia, Saunders
-
Fausto N: Hepatic regeneration; in Zakim D, Boyer TD (eds): Hepatology. A Text Book of Liver Disease, ed 3. Philadelphia, Saunders, 1996, pp 32-58.
-
(1996)
A Text Book of Liver Disease
, pp. 32-58
-
-
Fausto, N.1
-
13
-
-
0035179267
-
Influence of antiestrogens on NIH-3T3-fibroblast-induced motility of breast cancer cells
-
Rajah TT, Rambo DJ, Dmytryk JJ, Pento JT: Influence of antiestrogens on NIH-3T3-fibroblast-induced motility of breast cancer cells. Chemotherapy 2001;47:56-69.
-
(2001)
Chemotherapy
, vol.47
, pp. 56-69
-
-
Rajah, T.T.1
Rambo, D.J.2
Dmytryk, J.J.3
Pento, J.T.4
-
14
-
-
0024992594
-
Gene expression in regenerating and acute-phase rat liver
-
Milland J, Tsykin A, Thomas T, Aldred AR, Cole T, Schreiber G: Gene expression in regenerating and acute-phase rat liver. Am J Physiol 1990;259:G340-G347.
-
(1990)
Am J Physiol
, vol.259
-
-
Milland, J.1
Tsykin, A.2
Thomas, T.3
Aldred, A.R.4
Cole, T.5
Schreiber, G.6
-
15
-
-
0022550757
-
Transcriptional switch from albumin to alpha-fetoprotein and changes in transcription of other genes during carbon tetrachloride induced liver regeneration
-
Panduro A, Shalaby F, Weiner FR, Biempica L, Zern MA, Shafritz DA: Transcriptional switch from albumin to alpha-fetoprotein and changes in transcription of other genes during carbon tetrachloride induced liver regeneration. Biochemistry 1986;25:1414-1420.
-
(1986)
Biochemistry
, vol.25
, pp. 1414-1420
-
-
Panduro, A.1
Shalaby, F.2
Weiner, F.R.3
Biempica, L.4
Zern, M.A.5
Shafritz, D.A.6
-
16
-
-
0031883558
-
Enhancement of albumin production by hepatocyte growth factor in rat hepatocytes: Distinction in mode of action from stimulation of DNA synthesis
-
Yamaoka M, Hirata K, Ogata I, Tomiya T, Nagoshi S, Mochida S, Fujiwara K: Enhancement of albumin production by hepatocyte growth factor in rat hepatocytes: distinction in mode of action from stimulation of DNA synthesis. Liver 1998;18:52-59.
-
(1998)
Liver
, vol.18
, pp. 52-59
-
-
Yamaoka, M.1
Hirata, K.2
Ogata, I.3
Tomiya, T.4
Nagoshi, S.5
Mochida, S.6
Fujiwara, K.7
-
17
-
-
0026792940
-
Cell density-dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor
-
Takehara T, Matsumoto K, Nakamura T: Cell density-dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor. J Biochem 1992;112:330-334.
-
(1992)
J Biochem
, vol.112
, pp. 330-334
-
-
Takehara, T.1
Matsumoto, K.2
Nakamura, T.3
-
18
-
-
0026484294
-
Direct evidence that hepatocyte growth factor is a hepatotropic factor for liver regeneration and has a potent antihepatitis effect in vivo
-
Ishiki Y, Ohnishi H, Muto Y, Matsumoto K, Nakamura T: Direct evidence that hepatocyte growth factor is a hepatotropic factor for liver regeneration and has a potent antihepatitis effect in vivo. Hepatology 1992;16:1227-1235.
-
(1992)
Hepatology
, vol.16
, pp. 1227-1235
-
-
Ishiki, Y.1
Ohnishi, H.2
Muto, Y.3
Matsumoto, K.4
Nakamura, T.5
-
19
-
-
0027375855
-
Stimulation of liver growth by exogenous human hepatocyte growth factor in normal and partially hepatectomized rats
-
Fujiwara K, Nagoshi S, Ohno A, Hirata K, Ohta Y, Mochida S, Tomiya T, Higashio, K, Kurokawa K: Stimulation of liver growth by exogenous human hepatocyte growth factor in normal and partially hepatectomized rats. Hepatology 1993;18:1443-1449.
-
(1993)
Hepatology
, vol.18
, pp. 1443-1449
-
-
Fujiwara, K.1
Nagoshi, S.2
Ohno, A.3
Hirata, K.4
Ohta, Y.5
Mochida, S.6
Tomiya, T.7
Higashio, K.8
Kurokawa, K.9
-
20
-
-
0028040336
-
In vivo response of hepatocytes to growth factors requires an initial priming stimulus
-
Webber EM, Godowski PJ, Fausto N: In vivo response of hepatocytes to growth factors requires an initial priming stimulus. Hepatology 1994;19:489-497.
-
(1994)
Hepatology
, vol.19
, pp. 489-497
-
-
Webber, E.M.1
Godowski, P.J.2
Fausto, N.3
-
21
-
-
0041531109
-
Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism
-
Mead JE, Fausto N: Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc Natl Acad Sci USA 1989;86:1558-1562.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 1558-1562
-
-
Mead, J.E.1
Fausto, N.2
-
22
-
-
0025783985
-
Expression of hepatocyte growth factor mRNA in regenerating rat liver after partial hepatectomy
-
Zarnegar R, DeFrances MC, Kost DP, Lindroos P, Michalopoulos G: Expression of hepatocyte growth factor mRNA in regenerating rat liver after partial hepatectomy. Biochem Biophys Res Commun 1991;177:559-565.
-
(1991)
Biochem Biophys Res Commun
, vol.177
, pp. 559-565
-
-
Zarnegar, R.1
DeFrances, M.C.2
Kost, D.P.3
Lindroos, P.4
Michalopoulos, G.5
-
23
-
-
0027331503
-
Transforming growth factor-alpha expression during liver regeneration after partial hepatectomy and toxic injury, and potential interactions between transforming growth factor-alpha and hepatocyte growth factor
-
Webber EM, FitzGerald MJ, Brown PI, Bartlett MH, Fausto N: Transforming growth factor-alpha expression during liver regeneration after partial hepatectomy and toxic injury, and potential interactions between transforming growth factor-alpha and hepatocyte growth factor. Hepatology 1993;18:1422-1431.
-
(1993)
Hepatology
, vol.18
, pp. 1422-1431
-
-
Webber, E.M.1
FitzGerald, M.J.2
Brown, P.I.3
Bartlett, M.H.4
Fausto, N.5
-
24
-
-
0031685201
-
Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration
-
Tomiya T, Ogata I, Fujiwara K: Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration. Am J Pathol 1998;153:955-961.
-
(1998)
Am J Pathol
, vol.153
, pp. 955-961
-
-
Tomiya, T.1
Ogata, I.2
Fujiwara, K.3
-
25
-
-
0026712354
-
Serum hepatocyte growth factor levels in hepatectomized and nonhepatectomized surgical patients
-
Tomiya T, Tani M, Yamada S, Hayashi S, Umeda N, Fujiwara K: Serum hepatocyte growth factor levels in hepatectomized and nonhepatectomized surgical patients. Gastroenterology 1992;103:1621-1624.
-
(1992)
Gastroenterology
, vol.103
, pp. 1621-1624
-
-
Tomiya, T.1
Tani, M.2
Yamada, S.3
Hayashi, S.4
Umeda, N.5
Fujiwara, K.6
-
26
-
-
0026601033
-
Significance of serum human hepatocyte growth factor levels in patients with hepatic failure
-
Tomiya T, Nagoshi S, Fujiwara K: Significance of serum human hepatocyte growth factor levels in patients with hepatic failure. Hepatology 1992;15:1-4.
-
(1992)
Hepatology
, vol.15
, pp. 1-4
-
-
Tomiya, T.1
Nagoshi, S.2
Fujiwara, K.3
-
27
-
-
0027218227
-
Serum levels of transforming growth factor-alpha in patients after partial hepatectomy as determined with an enzyme-linked immunosorbent assay
-
Tomiya T, Fujiwara K: Serum levels of transforming growth factor-alpha in patients after partial hepatectomy as determined with an enzyme-linked immunosorbent assay. Hepatology 1993;18:304-308.
-
(1993)
Hepatology
, vol.18
, pp. 304-308
-
-
Tomiya, T.1
Fujiwara, K.2
-
28
-
-
0030939743
-
Serum transforming growth factor alpha level can be a parameter for evaluating liver regeneration after partial hepatectomy in patients with liver cancer
-
Tomiya T, Hayashi S, Yanase M, Umeda N, Tani M, Yamada S, Masaki N, Ogata I, Fujiwara K: Serum transforming growth factor alpha level can be a parameter for evaluating liver regeneration after partial hepatectomy in patients with liver cancer. Semin Oncol 1997;24:14-17.
-
(1997)
Semin Oncol
, vol.24
, pp. 14-17
-
-
Tomiya, T.1
Hayashi, S.2
Yanase, M.3
Umeda, N.4
Tani, M.5
Yamada, S.6
Masaki, N.7
Ogata, I.8
Fujiwara, K.9
-
29
-
-
0030042425
-
Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor alpha levels
-
Tomiya T, Fujiwara K: Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor alpha levels. Hepatology 1996;23:253-257.
-
(1996)
Hepatology
, vol.23
, pp. 253-257
-
-
Tomiya, T.1
Fujiwara, K.2
-
30
-
-
0017101039
-
Preparation of isolated rat liver cells
-
Seglen PO: Preparation of isolated rat liver cells. Methods Cell Biol 1976;13:29-83.
-
(1976)
Methods Cell Biol
, vol.13
, pp. 29-83
-
-
Seglen, P.O.1
-
31
-
-
27544495547
-
Effect of the farnesyl transferase inhibitor L-744,832 on the colon cancer cell line DLD-1 and its combined use with radiation and 5-FU
-
Kavgaci H, Ozdemir F, Ovali E, Yavuz A, Yavuz M, Aydin F: Effect of the farnesyl transferase inhibitor L-744,832 on the colon cancer cell line DLD-1 and its combined use with radiation and 5-FU. Chemotherapy 2005;51:319-323.
-
(2005)
Chemotherapy
, vol.51
, pp. 319-323
-
-
Kavgaci, H.1
Ozdemir, F.2
Ovali, E.3
Yavuz, A.4
Yavuz, M.5
Aydin, F.6
-
32
-
-
0025787867
-
Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: Cloning of its cDNA, purification and characterization of recombinant protein
-
Shima N, Nagao M, Ogaki F, Tsuda E, Murakami A, Higashio K: Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: cloning of its cDNA, purification and characterization of recombinant protein. Biochem Biophys Res Commun 1991;180:1151-1158.
-
(1991)
Biochem Biophys Res Commun
, vol.180
, pp. 1151-1158
-
-
Shima, N.1
Nagao, M.2
Ogaki, F.3
Tsuda, E.4
Murakami, A.5
Higashio, K.6
-
35
-
-
0029905271
-
The hepatocyte growth factor regulates the synthesis of acute-phase proteins in human hepatocytes: Divergent effect on interleukin-6-stimulated genes
-
Guillen MI, Gomez-Lechon MJ, Nakamura T, Castell JV: The hepatocyte growth factor regulates the synthesis of acute-phase proteins in human hepatocytes: divergent effect on interleukin-6-stimulated genes. Hepatology 1996;23:1345-1352.
-
(1996)
Hepatology
, vol.23
, pp. 1345-1352
-
-
Guillen, M.I.1
Gomez-Lechon, M.J.2
Nakamura, T.3
Castell, J.V.4
-
36
-
-
0020285970
-
Synthesis and secretion of plasma proteins by isolated hepatocytes of analbuminemic rats
-
Sugiyama K, Emori T, Nagase S: Synthesis and secretion of plasma proteins by isolated hepatocytes of analbuminemic rats. J Biochem 1982;92:775-779.
-
(1982)
J Biochem
, vol.92
, pp. 775-779
-
-
Sugiyama, K.1
Emori, T.2
Nagase, S.3
-
37
-
-
0034968334
-
Transcriptional control mechanism of fibrinogen gene expression
-
Fuller GM, Zhang Z: Transcriptional control mechanism of fibrinogen gene expression. Ann N Y Acad Sci 2001;936:469-479.
-
(2001)
Ann N Y Acad Sci
, vol.936
, pp. 469-479
-
-
Fuller, G.M.1
Zhang, Z.2
-
38
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
-
Chung J, Kuo CJ, Crabtree GR, Blenis J: Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 1992;69:1227-1236.
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
39
-
-
0036440779
-
Regulation of mammalian translation factors by nutrients
-
Proud CG: Regulation of mammalian translation factors by nutrients. Eur J Biochem 2002;269:5338-5349.
-
(2002)
Eur J Biochem
, vol.269
, pp. 5338-5349
-
-
Proud, C.G.1
-
40
-
-
0346996344
-
Regulation of global and specific mRNA translation by oral administration of branched-chain amino acids
-
Kimball SR, Jefferson LS: Regulation of global and specific mRNA translation by oral administration of branched-chain amino acids. Biochem Biophys Res Commun 2004;313:423-427.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 423-427
-
-
Kimball, S.R.1
Jefferson, L.S.2
-
41
-
-
0347627142
-
Regulation of protein synthesis by branched-chain amino acids in vivo
-
Yoshizawa F: Regulation of protein synthesis by branched-chain amino acids in vivo. Biochem Biophys Res Commun 2004;313:417-422.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 417-422
-
-
Yoshizawa, F.1
-
42
-
-
0032054816
-
The mRNA 5′ cap-binding protein eIF4E and control of cell growth
-
Sonenberg N, Gingras AC: The mRNA 5′ cap-binding protein eIF4E and control of cell growth. Curr Opin Cell Biol 1998;10:268-275.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 268-275
-
-
Sonenberg, N.1
Gingras, A.C.2
-
43
-
-
0029118603
-
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
-
Ui M, Okada T, Hazeki K, Hazeki O: Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 1995;20:303-307.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 303-307
-
-
Ui, M.1
Okada, T.2
Hazeki, K.3
Hazeki, O.4
|