A comprehensive gene expression analysis of human hepatocellular carcinoma cell lines as components of a bioartificial liver using a radial flow bioreactor

Liver International

Volumn 27, Issue 1, 2007, Pages 101-108

  Kosuge, Makoto ^a   Takizawa, Hiroko ^a   Maehashi, Haruka ^a   Matsuura, Tomokazu ^a   Matsufuji, Senya ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bioartificial liver; Gene expression analysis; Hepatocellular carcinoma; Human cell line; Micro array; Radial flow bioreactor

Indexed keywords

ALBUMIN; ALPHA FETOPROTEIN; AMMONIA; CYTOCHROME P450;

ARTICLE; BIOARTIFICIAL LIVER; BIOREACTOR; CANCER CELL CULTURE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CLUSTER ANALYSIS; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENETIC CODE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LIVER FUNCTION; METABOLIC PARAMETERS; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION;

ALBUMINS; ALPHA-FETOPROTEINS; BIOREACTORS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER, ARTIFICIAL;

EID: 33846426486     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2006.01410.x     Document Type: Article

References (27)

1. van de Kerkhove MP, Hoekstra R, Chamuleau RA, van Gulik TM. Clinical application of bioartificial liver support systems. Ann Surg 2004; 240: 216-30.
2. Nagamori S, Hasumura S, Matsuura T, Aizaki H, Kawada M. Developments in bioartificial liver research: Concepts, performance, and applications. J Gastroenterol 2000; 35: 493-503.
3. te Velde AA, Ladiges NC, Flendrig LM, Chamuleau RA. Functional activity of isolated pig hepatocytes attached to different extracellular matrix substrates. Implication for application of pig hepatocytes in a bioartificial liver. J Hepatol 1995; 23: 184-92.
4. Morsiani E, Brogli M, Galavotti D, et al. Long-term expression of highly differentiated functions by isolated porcine hepatocytes perfused in a radial-flow bioreactor. Artif Organs 2001; 25: 740-8.
5. Rozga J, Podesta L, LePage E, et al. Control of cerebral oedema by total hepatectomy and extracorporeal liver support in fulminant hepatic failure. Lancet 1993; 342: 898-9.
6. Neuzil DF, Rozga J, Moscioni AD, et al. Use of a novel bioartificial liver in a patient with acute liver insufficiency. Surgery 1993; 113: 340-3.
7. Sussman NL, Finegold MJ, Barish JP, Kelly JH. A case of syncytial giant-cell hepatitis treated with an extracorporeal liver assist device. Am J Gastroenterol 1994; 89: 1077-82.
8. Yamashita Y, Shimada M, Tsujita E, et al. Polyurethane form/spheroid culture system using human hepatoblastoma cell line (HepG2) as a possible new hybrid artificial liver. Cell Transplant 2001; 10: 717-22.
9. Takahashi M, Ishikura H, Takahashi C, et al. Immunologic considerations in the use of cultured porcine hepatocytes as a hybrid artificial liver. Anti-porcine hepatocyte human serum. ASAIO J 1993; 39: M242-6.
10. van der Laan LJ, Lockey C, Griffeth BC, et al. Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice. Nature 2000; 407: 90-4.
11. Fujise K, Nagamori S, Hasumura S, et al. Integration of hepatitis B virus DNA into cells of six established human hepatocellular carcinoma cell lines. Hepato Gastroenterol 1990; 37: 457-60.
12. Iwahori T, Matsuura T, Maehashi H, et al. CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartificial liver. Hepatology 2003; 37: 665-73.
13. Kawada M, Nagamori S, Aizaki H, et al. Massive culture of human liver cancer cells in a newly developed radial flow bioreactor system: ultrafine structure of functionally enhanced hepatocarcinoma cell lines. In Vitro Cell Dev Biol 1998; 34: 109-15.
14. Aizaki H, Nagamori S, Matsuda M, et al. Production and release of infectious hepatitis C virus from human liver cell cultures in the three-dimensional radial-flow bioreactor. Virology 2003; 314: 16-25.
15. Eisen BM, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 1998; 95: 14863-8.
16. Gorlin JB, Yamin R, Egan S, et al. Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): A molecular leaf spring. J Cell Biol 1990; 111: 1089-105.
17. Hasegawa H, Utsunomiya Y, Kishimoto K, Yanagisawa K, Fujita S. SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily. J Virol 1996; 70: 3258-263.
18. Zhang XA, Kazarov AR, Yang X, Bontrager AL, Stipp CS, Hemler ME. Function of the tetraspanin CD151-α6β1 integrin complex during cellular morphogenesis. Mol Biol Cell 2002; 13: 1-11.
19. Wu HK, Heng HH, Shi XM, et al. Differential expression of a basic helix-loop-helix phosphoprotein gene, G0S8, in acute leukemia and localization to human chromosome 1q31. Leukemia 1995; 9: 1291-8.
20. Nakamura M, Inufusa H, Adachi T, et al. Involvement of galectin-3 expression in colorectal cancer progression and metastasis. Int J Oncol 1999; 15: 143-8.
21. Wenger RH, Rolfs A, Marti HH, Bauer C, Gassmann M. Hypoxia, a novel inducer of acute phase gene expression in a human hepatoma cell line. J Biol Chem 1995; 270: 27865-70.
22. McClure D, Miller MR, Shiman R. Cell density dependent regulation of phenylalanine hydroxylase activity in hepatoma cells. Evidence for both an active and inactive enzyme form. Exp Cell Res 1976; 98: 223-36.
23. Tateishi T, Kumai T, Watanabe M, Tanaka M, Kobayashi S. A comparison of the effect of five phenothiazines on hepatic CYP isoenzymes in rats. Pharmacol Toxicol 1999; 85: 252-6.
24. +-ATPase inhibitors and other xenobiotics. Xenobiotica 2003; 33: 107-18.
25. Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB J 1996; 10: 267-82.
26. Kuo CJ, Conley PB, Chen L, Sladek FM, Darnell JE Jr, Crabtree GR. A transcriptional hierarchy involved in mammalian cell-type specification. Nature 1992; 355: 457-61.
27. Späth GF, Weiss MC. Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells. J Cell Biol 1998; 140: 935-46.