A method for therapeutic dose selection in a phase II clinical trial using contrast statistics

Statistics in Medicine

Volumn 26, Issue 3, 2007, Pages 498-511

  Wakana, Akira ^a   Yoshimura, Isao ^a   Hamada, Chikuma ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Clinical trial; Contrast; Dose response; Phase II; Response pattern; Therapeutic dose

Indexed keywords

LEUKOTRIENE RECEPTOR BLOCKING AGENT; PLACEBO;

ANALYSIS OF COVARIANCE; ARTICLE; ASTHMA; CLINICAL RESEARCH; CLINICAL TRIAL; DATA ANALYSIS; DRUG EFFICACY; DRUG RESEARCH; DRUG RESPONSE; DRUG SAFETY; HUMAN; PHASE 2 CLINICAL TRIAL; STATISTICAL ANALYSIS; VIRUS LOAD;

ASTHMA; CLINICAL TRIALS, PHASE II; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LEUKOTRIENE ANTAGONISTS; MODELS, STATISTICAL; PEAK EXPIRATORY FLOW RATE;

EID: 33846421062     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.2552     Document Type: Article

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