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Volumn 19, Issue 4, 2006, Pages 703-719

Sarcopenia: Age-related skeletal muscle changes from determinants to physical disability

Author keywords

Elderly; Inflammation; Sarcopenia; Signaling pathways

Indexed keywords

ANABOLIC AGENT; CORTICOSTEROID; CYTOKINE; GROWTH HORMONE; HYDROCORTISONE; LEPTIN; MUSCLE PROTEIN; OXYGEN RADICAL; PLACEBO; PRASTERONE SULFATE; SEX HORMONE; SOMATOMEDIN C; TESTOSTERONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 33846409030     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200601900401     Document Type: Review
Times cited : (49)

References (64)
  • 1
    • 0023856536 scopus 로고
    • What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men
    • Lexell J., C.C. Taylor and M. Sjostrom. 1988. What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. J. Neurol. Sci. 84:275.
    • (1988) J. Neurol. Sci , vol.84 , pp. 275
    • Lexell, J.1    Taylor, C.C.2    Sjostrom, M.3
  • 2
    • 33645141176 scopus 로고    scopus 로고
    • Influence of sarcopenia on the development of physical disability: The Cardiovascular Health Study
    • Janssen I. 2006. Influence of sarcopenia on the development of physical disability: the Cardiovascular Health Study. J. Am. Geriatr. Soc. 54:56.
    • (2006) J. Am. Geriatr. Soc , vol.54 , pp. 56
    • Janssen, I.1
  • 3
    • 0036246979 scopus 로고    scopus 로고
    • Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    • Janssen I., S.B. Heymsfield and R. Ross. 2002. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J. Am. Geriatr. Soc. 50:889.
    • (2002) J. Am. Geriatr. Soc , vol.50 , pp. 889
    • Janssen, I.1    Heymsfield, S.B.2    Ross, R.3
  • 6
    • 0036904691 scopus 로고    scopus 로고
    • Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women
    • Iannuzzi-Sucich M., K.M. Prestwood and A.M. Kenny. 2002. Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. J. Gerontol. A. Biol. Sci. Med. Sci. 57:772.
    • (2002) J. Gerontol. A. Biol. Sci. Med. Sci , vol.57 , pp. 772
    • Iannuzzi-Sucich, M.1    Prestwood, K.M.2    Kenny, A.M.3
  • 8
    • 0345447513 scopus 로고    scopus 로고
    • Sarcopenia: Effects on body composition and function
    • Roubenoff R. 2003. Sarcopenia: effects on body composition and function. J. Gerontol. A Biol. Sci. Med Sci. 58:1012.
    • (2003) J. Gerontol. A Biol. Sci. Med Sci , vol.58 , pp. 1012
    • Roubenoff, R.1
  • 10
    • 0033560860 scopus 로고    scopus 로고
    • Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation
    • McKoy G., W. Ashley, J. Mander, S.Y. Yang, N. Williams, B. Russell and G. Goldspink. 1999. Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation. J. Physiol. 516:583.
    • (1999) J. Physiol , vol.516 , pp. 583
    • McKoy, G.1    Ashley, W.2    Mander, J.3    Yang, S.Y.4    Williams, N.5    Russell, B.6    Goldspink, G.7
  • 11
    • 0037440667 scopus 로고    scopus 로고
    • Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise
    • Hameed M., R.W. Orrell, M. Cobbold, G. Goldspink and S.D. Harridge. 2003. Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise. J. Physiol. 547:247.
    • (2003) J. Physiol , vol.547 , pp. 247
    • Hameed, M.1    Orrell, R.W.2    Cobbold, M.3    Goldspink, G.4    Harridge, S.D.5
  • 12
    • 23944456384 scopus 로고    scopus 로고
    • Skeletal muscle hypertrophy and atrophy signaling pathways
    • Glass D.J. 2005. Skeletal muscle hypertrophy and atrophy signaling pathways. Int. J. Biochem. Cell. Biol 37:1974.
    • (2005) Int. J. Biochem. Cell. Biol , vol.37 , pp. 1974
    • Glass, D.J.1
  • 13
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S., R. Loewith and M.N. Hall. 2006. TOR signaling in growth and metabolism. Cell 124:471.
    • (2006) Cell , vol.124 , pp. 471
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 14
    • 33746611524 scopus 로고    scopus 로고
    • Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle
    • Edstrom E., M. Altun, M. Hagglund and B. Ulfhake. 2006. Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. J. Gerontol. A Biol. Sci. Med Sci. 61:663.
    • (2006) J. Gerontol. A Biol. Sci. Med Sci , vol.61 , pp. 663
    • Edstrom, E.1    Altun, M.2    Hagglund, M.3    Ulfhake, B.4
  • 15
    • 23944480371 scopus 로고
    • Molecular determinants of skeletal muscle mass: Getting the "AKT" together
    • Nader G.A. 2005. Molecular determinants of skeletal muscle mass: getting the "AKT" together. Int. J. Biochem. Cell. Biol. 37:1985.
    • (1985) Int. J. Biochem. Cell. Biol , vol.37
    • Nader, G.A.1
  • 16
    • 13244298415 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway
    • Latres E., A.R. Amini, A.A. Amini, J. Griffiths, F.J. Martin, Y. Wei, H.C. Lin, G.D. Yancopoulos and D.J. Glass. 2005. Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway. J. Biol Chem. 280:2737.
    • (2005) J. Biol Chem , vol.280 , pp. 2737
    • Latres, E.1    Amini, A.R.2    Amini, A.A.3    Griffiths, J.4    Martin, F.J.5    Wei, Y.6    Lin, H.C.7    Yancopoulos, G.D.8    Glass, D.J.9
  • 17
    • 0034698695 scopus 로고    scopus 로고
    • Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger protein
    • Spencer J.A., S. Eliazer, R.L. Ilaria Jr., J.A. Richardson and E.N. Olson. 2000. Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger protein. J. Cell Biol. 150:771.
    • (2000) J. Cell Biol , vol.150 , pp. 771
    • Spencer, J.A.1    Eliazer, S.2    Ilaria Jr., R.L.3    Richardson, J.A.4    Olson, E.N.5
  • 18
    • 0036544533 scopus 로고    scopus 로고
    • Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1
    • McElhinny A.S., K. Kakinuma, H. Sorimachi, S. Labeit and C.C. Gregorio. 2002. Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1. J. Cell Biol. 157:125.
    • (2002) J. Cell Biol , vol.157 , pp. 125
    • McElhinny, A.S.1    Kakinuma, K.2    Sorimachi, H.3    Labeit, S.4    Gregorio, C.C.5
  • 19
    • 33745712387 scopus 로고    scopus 로고
    • Functional properties of the titin/connectin-associated proteins, the muscle-specific RING finger proteins (MURFs), in striated muscle
    • Gregorio C.C., C.N. Perry and A.S. McElhinny. 2005. Functional properties of the titin/connectin-associated proteins, the muscle-specific RING finger proteins (MURFs), in striated muscle. J. Muscle Res. Cell Motil. 26:389.
    • (2005) J. Muscle Res. Cell Motil , vol.26 , pp. 389
    • Gregorio, C.C.1    Perry, C.N.2    McElhinny, A.S.3
  • 21
    • 32144457727 scopus 로고    scopus 로고
    • Intracellular signaling during skeletal muscle atrophy
    • Kandarian S.C. and R.W. Jackman. 2006. Intracellular signaling during skeletal muscle atrophy. Muscle Nerve 33:155.
    • (2006) Muscle Nerve , vol.33 , pp. 155
    • Kandarian, S.C.1    Jackman, R.W.2
  • 22
    • 1842339868 scopus 로고    scopus 로고
    • Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles
    • Tawa N.E. Jr., R. Odessey and A.L. Goldberg. 1997. Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles. J. Clin. Invest. 100:197.
    • (1997) J. Clin. Invest , vol.100 , pp. 197
    • Tawa Jr., N.E.1    Odessey, R.2    Goldberg, A.L.3
  • 23
    • 0346727127 scopus 로고    scopus 로고
    • Protein degradation and protection against misfolded or damaged proteins
    • Goldberg A.L. 2003. Protein degradation and protection against misfolded or damaged proteins. Nature 426:895.
    • (2003) Nature , vol.426 , pp. 895
    • Goldberg, A.L.1
  • 25
    • 0041343008 scopus 로고    scopus 로고
    • Di Iorio A., L. Ferrucci, E. Sparvieri, A. Cherubini, S. Volpato, A. Corsi, M. Bonafe, C. Franceschi, G. Abate and R. Paganelli. 2003. Serum IL-1beta levels in health and disease: a population-based study. 'The In CHIANTI study'. Cytokine 22:198.
    • Di Iorio A., L. Ferrucci, E. Sparvieri, A. Cherubini, S. Volpato, A. Corsi, M. Bonafe, C. Franceschi, G. Abate and R. Paganelli. 2003. Serum IL-1beta levels in health and disease: a population-based study. 'The In CHIANTI study'. Cytokine 22:198.
  • 32
    • 0036136997 scopus 로고    scopus 로고
    • Aging of the human neuromuscular system
    • Vandervoort A.A. 2002. Aging of the human neuromuscular system. Muscle Nerve 25:17.
    • (2002) Muscle Nerve , vol.25 , pp. 17
    • Vandervoort, A.A.1
  • 34
    • 33748095030 scopus 로고    scopus 로고
    • When sparks get old
    • Melzer W. 2006. When sparks get old. J. Cell Biol. 174:613.
    • (2006) J. Cell Biol , vol.174 , pp. 613
    • Melzer, W.1
  • 35
    • 24144489118 scopus 로고    scopus 로고
    • Cellular and molecular signatures of muscle regeneration: Current concepts and controversies in adult myogenesis
    • Wagers A.J. and I.M. Conboy. 2005. Cellular and molecular signatures of muscle regeneration: current concepts and controversies in adult myogenesis. Cell 122:659.
    • (2005) Cell , vol.122 , pp. 659
    • Wagers, A.J.1    Conboy, I.M.2
  • 36
    • 6944224363 scopus 로고    scopus 로고
    • Growth factors and muscle ageing
    • Goldspink G. and S.D. Harridge. 2004. Growth factors and muscle ageing. Exp. Gerontol. 39:1433.
    • (2004) Exp. Gerontol , vol.39 , pp. 1433
    • Goldspink, G.1    Harridge, S.D.2
  • 37
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron A.C., A.M. Lawler and S.J. Lee. 1997. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387:83.
    • (1997) Nature , vol.387 , pp. 83
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 38
    • 25444478907 scopus 로고    scopus 로고
    • Aging, stem cells and tissue regeneration: Lessons from muscle
    • Conboy I.M. and T.A. Rando. 2005. Aging, stem cells and tissue regeneration: lessons from muscle. Cell Cycle 4:407.
    • (2005) Cell Cycle , vol.4 , pp. 407
    • Conboy, I.M.1    Rando, T.A.2
  • 39
    • 0344827208 scopus 로고    scopus 로고
    • Notch-mediated restoration of regenerative potential to aged muscle
    • Conboy I.M., M.J. Conboy, G.M. Smythe and T.A. Rando. 2003. Notch-mediated restoration of regenerative potential to aged muscle. Science 302:1575,
    • (2003) Science , vol.302 , pp. 1575
    • Conboy, I.M.1    Conboy, M.J.2    Smythe, G.M.3    Rando, T.A.4
  • 40
    • 0036758313 scopus 로고    scopus 로고
    • Diagnosis of hypogonadism in the aging male
    • Vermeulen A. and J.M. Kaufman. 2002. Diagnosis of hypogonadism in the aging male. Aging Male 5:170.
    • (2002) Aging Male , vol.5 , pp. 170
    • Vermeulen, A.1    Kaufman, J.M.2
  • 44
    • 20144368778 scopus 로고    scopus 로고
    • Stress, glucocorticoids and ageing of the immune system
    • Bauer M.E. 2005. Stress, glucocorticoids and ageing of the immune system. Stress 8:69.
    • (2005) Stress , vol.8 , pp. 69
    • Bauer, M.E.1
  • 45
    • 3042712411 scopus 로고    scopus 로고
    • Of worms and women: Sarcopenia and its role in disability and mortality
    • Fisher A.L. 2004. Of worms and women: sarcopenia and its role in disability and mortality. J. Am. Geriatr. Soc. 52:1185.
    • (2004) J. Am. Geriatr. Soc , vol.52 , pp. 1185
    • Fisher, A.L.1
  • 46
    • 13944283022 scopus 로고    scopus 로고
    • Longevity and lineages: Toward the integrative biology of degenerative diseases in heart, muscle and bone
    • Chien K.R. and G. Karsenty. 2005. Longevity and lineages: toward the integrative biology of degenerative diseases in heart, muscle and bone. Cell 120:533.
    • (2005) Cell , vol.120 , pp. 533
    • Chien, K.R.1    Karsenty, G.2
  • 47
    • 0032416479 scopus 로고    scopus 로고
    • Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function
    • Barton-Davis E.R., D.I. Shoturma, A. Musaro, N. Rosenthal and H.L. Sweeney. 1998. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc. Natl. Acad. Sci USA 95:15603.
    • (1998) Proc. Natl. Acad. Sci USA , vol.95 , pp. 15603
    • Barton-Davis, E.R.1    Shoturma, D.I.2    Musaro, A.3    Rosenthal, N.4    Sweeney, H.L.5
  • 49
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee S.J. 2004. Regulation of muscle mass by myostatin. Annu. Rev. Cell Dev. Biol. 20:61.
    • (2004) Annu. Rev. Cell Dev. Biol , vol.20 , pp. 61
    • Lee, S.J.1
  • 50
    • 13944253348 scopus 로고    scopus 로고
    • Calorie restriction-the SIR2 connection
    • Guarente L. and F. Picard. 2005. Calorie restriction-the SIR2 connection. Cell 120:473.
    • (2005) Cell , vol.120 , pp. 473
    • Guarente, L.1    Picard, F.2
  • 52
    • 4644335766 scopus 로고    scopus 로고
    • Physical frailty and body composition in obese elderly men and women
    • Villareal D.T., M. Banks, C. Siener, D.R. Sinacore and S. Klein. 2004. Physical frailty and body composition in obese elderly men and women. Obes. Res. 12:913.
    • (2004) Obes. Res , vol.12 , pp. 913
    • Villareal, D.T.1    Banks, M.2    Siener, C.3    Sinacore, D.R.4    Klein, S.5
  • 53
    • 0031012270 scopus 로고    scopus 로고
    • Disability in older adults: Evidence regarding significance, etiology and risk
    • Fried L.P. and J.M. Guralnik. 1997. Disability in older adults: evidence regarding significance, etiology and risk. J. Am. Geriatr. Soc. 45:92.
    • (1997) J. Am. Geriatr. Soc , vol.45 , pp. 92
    • Fried, L.P.1    Guralnik, J.M.2
  • 54
    • 0032896456 scopus 로고    scopus 로고
    • Association of comorbidity with disability in older women: The Women's Health and Aging Study
    • Fried L.P., K. Bandeen-Roche, J.D. Kasper and J.M. Guralnik. 1999. Association of comorbidity with disability in older women: the Women's Health and Aging Study. J. Clin. Epidemiol. 52:27.
    • (1999) J. Clin. Epidemiol , vol.52 , pp. 27
    • Fried, L.P.1    Bandeen-Roche, K.2    Kasper, J.D.3    Guralnik, J.M.4
  • 55
    • 0036843564 scopus 로고    scopus 로고
    • Physical activity as a determinant of change in mobility performance: The Longitudinal Aging Study Amsterdam
    • Visser M., S.M. Pluijm, V.S. Stel, R.J. Bosscher and D.J. Deeg. 2002. Physical activity as a determinant of change in mobility performance: the Longitudinal Aging Study Amsterdam. J. Am. Geriatr. Soc. 50:1774.
    • (2002) J. Am. Geriatr. Soc , vol.50 , pp. 1774
    • Visser, M.1    Pluijm, S.M.2    Stel, V.S.3    Bosscher, R.J.4    Deeg, D.J.5
  • 57
    • 0025090868 scopus 로고
    • Function, morphology and protein expression of ageing skeletal muscle: A cross-sectional study of elderly men with different training backgrounds
    • Klitgaard H., M. Mantoni, S. Schiaffino, S. Ausoni, L. Gorza, C. Laurent-Winter, P. Schnohr and B. Saltin. 1990. Function, morphology and protein expression of ageing skeletal muscle: a cross-sectional study of elderly men with different training backgrounds. Acta Physiol. Scand. 140:41.
    • (1990) Acta Physiol. Scand , vol.140 , pp. 41
    • Klitgaard, H.1    Mantoni, M.2    Schiaffino, S.3    Ausoni, S.4    Gorza, L.5    Laurent-Winter, C.6    Schnohr, P.7    Saltin, B.8
  • 58
    • 29344473757 scopus 로고    scopus 로고
    • Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality
    • Mitnitski A., X. Song, I. Skoog, G. Broe, J.L. Cox, E. Grunfeld and K. Rockwood. 2005. Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J. Am. Geriatr. Soc. 53:2184.
    • (2005) J. Am. Geriatr. Soc , vol.53 , pp. 2184
    • Mitnitski, A.1    Song, X.2    Skoog, I.3    Broe, G.4    Cox, J.L.5    Grunfeld, E.6    Rockwood, K.7
  • 62
    • 0036904906 scopus 로고    scopus 로고
    • Exercise in the oldest old: Some new insights and unanswered questions
    • Fiatarone Singh M.A. 2002. Exercise in the oldest old: some new insights and unanswered questions. J. Am. Geriatr. Soc. 50:2089.
    • (2002) J. Am. Geriatr. Soc , vol.50 , pp. 2089
    • Fiatarone Singh, M.A.1
  • 63
    • 0024319271 scopus 로고
    • Dietary protein requirements and body protein metabolism in endurance-trained men
    • Meredith C.N., M.J. Zackin, W.R. Frontera and W.J. Evans. 1989. Dietary protein requirements and body protein metabolism in endurance-trained men. J. Appl Physiol. 66:2850.
    • (1989) J. Appl Physiol , vol.66 , pp. 2850
    • Meredith, C.N.1    Zackin, M.J.2    Frontera, W.R.3    Evans, W.J.4


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